Staff member

Pau Gorostiza Langa
Group Leader / ICREA Research Professor
Nanoprobes and Nanoswitches
+34 934 020 208
Staff member publications

Gómez-Santacana, Xavier, Pittolo, Silvia, Rovira, Xavier, Lopez, Marc, Zussy, Charleine, Dalton, James A. R., Faucherre, Adèle, Jopling, Chris, Pin, Jean-Philippe, Ciruela, Francisco, Goudet, Cyril, Giraldo, Jesús, Gorostiza, Pau, Llebaria, Amadeu, (2017). Illuminating phenylazopyridines to photoswitch metabotropic glutamate receptors: From the flask to the animals ACS Central Science 3, (1), 81-91 [Open Access]

Gómez-Santacana, Xavier, Dalton, James A. R., Rovira, Xavier, Pin, Jean Philippe, Goudet, Cyril, Gorostiza, Pau, Giraldo, Jesús, Llebaria, Amadeu, (2017). Positional isomers of bispyridine benzene derivatives induce efficacy changes on mGlu5 negative allosteric modulation European Journal of Medicinal Chemistry 127, 567-576

Rovira, Xavier, Trapero, Ana, Pittolo, Silvia, Zussy, Charleine, Faucherre, Adèle, Jopling, Chris, Giraldo, Jesús, Pin, Jean-Philippe, Gorostiza, Pau, Goudet, Cyril, Llebaria, Amadeu, (2016). OptoGluNAM4.1, a Photoswitchable allosteric antagonist for real-time control of mGlu4 receptor activity Cell Chemical Biology 23, (8), 929-934

Izquierdo-Serra, M., Bautista-Barrufet, A., Trapero, A., Garrido-Charles, A., Diaz-Tahoces, A., Camarero, N., Pittolo, S., Valbuena, S., Perez-Jimenez, A., Gay, M., Garcia-Moll, A., Rodriguez-Escrich, C., Lerma, J., De La Villa, P., Fernandez, E., Pericas, M. A., Llebaria, A., Gorostiza, P., (2016). Optical control of endogenous receptors and cellular excitability using targeted covalent photoswitches Nature Communications 7, 12221

A. R. Dalton, J., Lans, I., Rovira, X., Malhaire, F., Gómez-Santacana, X., Pittolo, S., Gorostiza, P., Llebaria, A., Goudet, C., Pin, J-P., Giraldo, J., (2016). Shining light on an mGlu5 photoswitchable NAM: A theoretical perspective Current Neuropharmacology 14, (5), 441-454

Martín-Quirós, Andrés, Nevola, Laura, Eckelt, Kay, Madurga, Sergio, Gorostiza, Pau, Giralt, Ernest, (2015). Absence of a stable secondary structure is not a limitation for photoswitchable inhibitors of Chemistry & Biology 22, (1), 31-37

Gascón-Moya, Marta, Pejoan, Arnau, Izquierdo-Serra, M., Pittolo, Silvia, Cabrè, Gisela, Hernando, Jordi, Alibés, Ramon, Gorostiza, Pau, Busque, Felix, (2015). An optimized glutamate receptor photoswitch with sensitized azobenzene isomerization Journal of Organic Chemistry 80, (20), 9915-9925

Giannotti, Marina I., Cabeza de Vaca, Israel, Artés, Juan Manuel, Sanz, Fausto, Guallar, Victor, Gorostiza, Pau, (2015). Direct measurement of the nanomechanical stability of a redox protein active site and its dependence upon metal binding Journal of Physical Chemistry B 119, (36), 12050-12058

Eckelt, Kay, Masanas, Helena, Llobet, Artur, Gorostiza, P., (2014). Automated high-throughput measurement of body movements and cardiac activity of Xenopus tropicalis tadpoles Journal of Biological Methods 1, (2), e9

Pittolo, Silvia, Gómez-Santacana, Xavier, Eckelt, Kay, Rovira, Xavier, Dalton, James, Goudet, Cyril, Pin, Jean-Philippe, Llobet, Artur, Giraldo, Jesús, Llebaria, Amadeu, Gorostiza, Pau, (2014). An allosteric modulator to control endogenous G protein-coupled receptors with light Nature Chemical Biology 10, (10), 813-815

Izquierdo-Serra, M., Gascón-Moya, Marta, Hirtz, Jan J., Pittolo, Silvia, Poskanzer, Kira E., Ferrer, Eric, Alibés, Ramon, Busque, Felix, Yuste, Rafael, Hernando, Jordi, Gorostiza, Pau, (2014). Two-photon neuronal and astrocytic stimulation of azobenzene-based photoswitches Journal of the American Chemical Society American Chemical Society 136, (24), 8693-8701

Bautista-Barrufet, A., López-Gallego, F., Rojas-Cervellera, V., Rovira, C., Pericàs, M. A., Guisán, J. M., Gorostiza, P., (2014). Optical control of enzyme enantioselectivity in solid phase ACS Catalysis 4, (3), 1004-1009

Artés, Juan M., López-Martínez, Montserrat, Díez-Pérez, Ismael, Sanz, Fausto, Gorostiza, Pau, (2014). Conductance switching in single wired redox proteins Small 10, (13), 2537-2541

Lagunas, A., Garcia, A., Artés, J. M., Vida, Y., Collado, D., Pérez-Inestrosa, E., Gorostiza, P., Claros, S., Andrades, J. A., Samitier, J., (2014). Large-scale dendrimer-based uneven nanopatterns for the study of local arginine-glycine-aspartic acid (RGD) density effects on cell adhesion Nano Research 7, (3), 399-409

Bahamonde, María Isabel, Taura, Jaume, Paoletta, Silvia, Gakh, Andrei Alexandrovich, Chakraborty, Saibal, Hernando, Jordi, Fernández-Dueñas, Víctor, Jacobson, Kenneth A., Gorostiza, Pau, Ciruela, Francisco, (2014). Photomodulation of G protein-coupled adenosine receptors by a novel light-switchable ligand Bioconjugate Chemistry American Chemical Society 25, (10), 1847-1854

Artés, J. M., López-Martínez, M., Díez-Pérez, I., Sanz, F., Gorostiza, P., (2014). Nanoscale charge transfer in redox proteins and DNA: Towards biomolecular electronics Electrochimica Acta 140, 83-95

Gomez-Santacana, X., Rovira, X., Dalton, J. A., Goudet, C., Pin, J. P., Gorostiza, P., Giraldo, J., Llebaria, A., (2014). A double effect molecular switch leads to a novel potent negative allosteric modulator of metabotropic glutamate receptor 5 MedChemComm 5, (10), 1548-1554

Bautista-Barrufet, Antoni, Izquierdo-Serra, M., Gorostiza, Pau, (2014). Photoswitchable Ion Channels and Receptors Advances in Atom and Single Molecule Machines Springer Berlin Heidelberg , 169-188

Gorostiza, Pau, Arosio, Daniele, Bregestovski, Piotr, (2013). Molecular probes and switches for functional analysis of receptors, ion channels and synaptic networks Frontiers in Molecular Neuroscience 6, (Article 48), 1-2

Izquierdo-Serra, Mercè, Trauner, Dirk, Llobet, Artur, Gorostiza, Pau, (2013). Optical modulation of neurotransmission using calcium photocurrents through the ion channel LiGluR Frontiers in Molecular Neuroscience 6, (Article 3), 1-6

Nevola, L., Martín-Quirós, A., Eckelt, K., Camarero, N., Tosi, S., Llobet, A., Giralt, E., Gorostiza, P., (2013). Light-regulated stapled peptides to inhibit protein-protein interactions involved in clathrin-mediated endocytosis Angewandte Chemie - International Edition 52, (30), 7704-7708

Izquierdo-Serra, Mercè, Trauner, Dirk, Llobet, Artur, Gorostiza, Pau, (2013). Optical control of calcium-regulated exocytosis Biochimica et Biophysica Acta (BBA) - General Subjects 1830, (3), 2853-2860

Raster, P., Späth, A., Bultakova, S., Gorostiza, P., König, B., Bregestovski, P., (2013). New GABA amides activating GABAA-receptors Beilstein Journal of Organic Chemistry 9, 406-410

Gorostiza, Pau, (2012). Control celular mediante luz Investigación y Ciencia 433, 11-12

Artés, Juan M., Díez-Pérez, Ismael, Gorostiza, Pau, (2012). Transistor-like behavior of single metalloprotein junctions Nano Letters 12, (6), 2679-2684

Artés, Juan M., López-Martínez, Montserrat, Giraudet, Arnaud, Díez-Pérez, Ismael, Sanz, Fausto, Gorostiza, Pau, (2012). Current–Voltage characteristics and transition voltage spectroscopy of individual redox proteins Journal of the American Chemical Society 134, (50), 20218-20221

Simao, C., Mas-Torrent, M., Crivillers, N., Lloveras, V., Artés, Juan Manuel, Gorostiza, Pau, Veciana, Jaume, Rovira, C., (2011). A robust molecular platform for non-volatile memory devices with optical and magnetic responses Nature Chemistry 3, (5), 359-364

Artés, Juan M., Díez-Pérez, Ismael, Sanz, Fausto, Gorostiza, Pau, (2011). Direct measurement of electron transfer distance decay constants of single redox proteins by electrochemical tunneling spectroscopy ACS Nano 5, (3), 2060-2066

Gorostiza, P., Isacoff, E.Y., (2011). Photoswitchable ligand-gated ion channels Springer 55, 267-285

Caballero-Briones, F., Artes, J. M., Diez-Perez, I., Gorostiza, P., Sanz, F., (2009). Direct observation of the valence band edge by in situ ECSTM-ECTS in p-type Cu2O layers prepared by copper anodization Journal of Physical Chemistry C 113, (3), 1028-1036

Gorostiza, P., Isacoff, E. Y., (2008). Optical switches for remote and noninvasive control of cell signaling Science 322, (5900), 395-399

Gorostiza, P., Isacoff, E. Y., (2008). Nanoengineering ion channels for optical control Physiology 23, (5), 238-247

Díez-Pérez, Ismael, Guell, Aleix Garcia, Sanz, Fausto, Gorostiza, Pau, (2006). Conductance maps by electrochemical tunneling spectroscopy to fingerprint the electrode electronic structure Analytical Chemistry 78, (20), 7325-7329

Díez-Pérez, Ismael, Sanz, Fausto, Gorostiza, Pau, (2006). Electronic barriers in the iron oxide film govern its passivity and redox behavior: Effect of electrode potential and solution pH Electrochemistry Communications 8, (10), 1595-1602

Díez-Pérez, Ismael, Vericat, Carolina, Gorostiza, Pau, Sanz, Fausto, (2006). The iron passive film breakdown in chloride media may be mediated by transient chloride-induced surface states located within the band gap Electrochemistry Communications 8, (4), 627-632

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