Staff member


George Altankov

Group Leader / ICREA Research Professor
Molecular Dynamics at Cell-Biomaterial Interface
galtankov@ibecbarcelona.eu
+34 934 039 709
CV Summary

George Altankov received his MD in 1974 from the Medical University of Varna (Bulgaria) where he also started his research career as Assistant Professor of Physiology. After obtaining his PhD he joined a research team at the Institute of Biophysics, Bulgarian Academy of Sciences, advancing to Associate Professor (1995) and Full Professor (2004) as well as Head of the Cell Adhesion Department (2004-2007) and Research Director of the institute (2004-2006). In 2003 he obtained a Doctor of Sciences degree in Cell Biology. In 1991-1993 he joined the group of Fred Grinnell in Southwestern Medical Center at Dallas and later visited several leading laboratories in Europe, including Humboldt University, GKSS Research Center (Berlin), Technical University of Barcelona and others, working on joint projects. He was awarded a Marie Curie senior EU fellowship and a Sabbatical Grant of the Spanish Ministry (2006). He has published more than 100 original papers and filed several patents in the field of cell-biomaterials interaction and tissue engineering. Since April 2007 he has been an ICREA Research Professor at the Institute for Bioengineering of Catalonia (IBEC), continuing his research in the field with emphasis on the organization of extracellular matrix at biomaterials interfaces.

Staff member publications

Gugutkov, D., Gustavsson, J., Cantini, M., Salmeron-Sánchez, M., Altankov, G., (2017). Electrospun fibrinogen-PLA nanofibres for vascular tissue engineering Journal of Tissue Engineering and Regenerative Medicine ,

Gugutkov, D., Awaja, F., Belemezova, K., Keremidarska, M., Krasteva, N., Kuyrkchiev, S., GallegoFerrer, G., Seker, S., Elcin, A. E., Elcin, Y. M., Altankov, G., (2017). Osteogenic differentiation of mesenchymal stem cells using hybrid nanofibers with different configurations and dimensionality Journal of Biomedical Materials Research - Part A ,

Zhao, M., Altankov, G., Grabiec, U., Bennett, M., Salmeron-Sanchez, M., Dehghani, F., Groth, T., (2016). Molecular composition of GAG-collagen I multilayers affects remodeling of terminal layers and osteogenic differentiation of adipose-derived stem cells Acta Biomaterialia 41, 86-99

Forget, J., Awaja, F., Gugutkov, D., Gustavsson, J., Gallego Ferrer, G., Coelho-Sampaio, T., Hochman-Mendez, C., Salmeron-Sánchez, M., Altankov, G., (2016). Differentiation of human mesenchymal stem cells toward quality cartilage using fibrinogen-based nanofibers Macromolecular Bioscience 16, (9), 1348-1359

Coelho, N. M., Llopis-Hernández, V., Salmerón-Sánchez, M., Altankov, G., (2016). Dynamic reorganization and enzymatic remodeling of type IV collagen at cell–biomaterial interface Academic Press 105, 81-104

Toromanov, Georgi, Gugutkov, Dencho, Gustavsson, Johan, Planell, Josep, Salmerón-Sánchez, Manuel, Altankov, George, (2015). Dynamic behavior of vitronectin at the cell-material interface ACS Biomaterials Science & Engineering 1, (10), 927-934

Keremidarska, M., Gugutkov, D., Altankov, G., Krasteva, N., (2015). Impact of electrospun nanofibres orientation on mesenchymal stem cell adhesion and morphology Comptes Rendus de L'Academie Bulgare des Sciences 68, (10), 1271-1276

Rico, P., Cantini, M., Altankov, G., Sanchez, M. , (2015). Matrix-protein interactions with synthetic surfaces John Wiley & Sons Inc , 91-146

Groth, T., Guduru, D., Altankov, George, Zenoby-Wong, M., Millan, C., Cavalli, E., Kesti, M., (2014). Procedure for making scaffold structures for tissue engineering applications, implants and surgery grafts by means of layer-by-layer method Martin Lutter University-Halle-Wittenberg; Fundació Institut de Bioenginyeria de Catalunya; Eidgenoessische Technische Hochschule Zuerich , (DE 10 2014 017 950.8),

Perez, Roman A., Riccardi, Kiara, Altankov, George, Ginebra, Maria-Pau, (2014). Dynamic cell culture on calcium phosphate microcarriers for bone tissue engineering applications Journal of Tissue Engineering 5, 2041731414543965

Gugutkov, Dencho, Gustavsson, Johan, Ginebra, Maria Pau, Altankov, George, (2013). Fibrinogen nanofibers for guiding endothelial cell behavior Biomaterials Science 1, (10), 1065-1073

Coelho, Nuno Miranda, Salmeron-Sanchez, Manuel, Altankov, George, (2013). Fibroblasts remodeling of type IV collagen at a biomaterials interface Biomaterials Science 1, (5), 494-502

Llopis-Hernández, V., Rico, P., Moratal, D., Altankov, George, Salmeron-Sanchez, Manuel, (2013). Role of material-driven fibronectin fibrillogenesis in protein remodeling BioResearch Open Access 2, (5), 364-373

Perez, R. A., Altankov, G., Jorge-Herrero, E., Ginebra, M. P., (2013). Micro- and nanostructured hydroxyapatite-collagen microcarriers for bone tissue-engineering applications Journal of Tissue Engineering and Regenerative Medicine 7, (5), 353-361

González-García, C., Cantini, M., Moratal, D., Altankov, G., Salmerón-Sánchez, M., (2013). Vitronectin alters fibronectin organization at the cell-material interface Colloids and Surfaces B: Biointerfaces 111, 618-625

Pecheva, E., Pramatarova, L., Hikov, T., Hristova, K., Altankov, G., Montgomery, P., Hanawa, T., (2012). Electrodeposition of hydroxyapatite-nanodiamond composite coating on metals, interaction with proteins and osteoblast-like cells Nova Publishers Electrical Engineering Developments, 233-253

Miranda Coelho, Nuno, Gonzalez-Garcia, Cristina, Salmeron-Sanchez, Manuel, Altankov, George, (2011). Arrangement of type IV collagen and laminin on substrates with controlled density of -OH groups Tissue Engineering Part A 17, (17-18), 2245-2257

Miranda Coelho, Nuno, Gonzalez-Garcia, Cristina, Salmeron-Sanchez, Manuel, Altankov, George, (2011). Arrangement of type IV collagen on NH(2) and COOH functionalized surfaces Biotechnology and Bioengineering 108, (12), 3009-3018

Gugutkov, Dencho, Gonzalez-Garcia, Cristina, Altankov, George, Salmeron-Sanchez, Manuel, (2011). Fibrinogen organization at the cell-material interface directs endothelial cell behavior Journal of Bioactive and Compatible Polymers 26, (4), 375-387

Hristova, K., Pecheva, E., Pramatarova, L., Altankov, G., (2011). Improved interaction of osteoblast-like cells with apatite-nanodiamond coatings depends on fibronectin Journal of Materials Science: Materials in Medicine 22, (8), 1891-1900

Perez, R. A., Del Valle, S., Altankov, G., Ginebra, M. P., (2011). Porous hydroxyapatite and gelatin/hydroxyapatite microspheres obtained by calcium phosphate cement emulsion Journal of Biomedical Materials Research - Part B: Applied Biomaterials 97B, (1), 156-166

Coelho, N. M., Gonzalez-Garcia, C., Planell, J. A., Salmeron-Sanchez, M., Altankov, G., (2010). Different assembly of type iv collagen on hydrophilic and hydrophobic substrata alters endothelial cells interaction European Cells & Materials 19, 262-272

Pegueroles, M., Aparicio, C., Bosio, M., Engel, E., Gil, F. J., Planell, J. A., Altankov, G., (2010). Spatial organization of osteoblast fibronectin matrix on titanium surfaces: Effects of roughness, chemical heterogeneity and surface energy Acta Biomaterialia 6, (1), 291-301

Toromanov, Georgi, González-García, Cristina, Altankov, George, Salmerón-Sánchez, Manuel, (2010). Vitronectin activity on polymer substrates with controlled -OH density Polymer 51, (11), 2329-2336

Gugutkov, D., Altankov, G., Hernandez, J. C. R., Pradas, M. M., Sanchez, M. S., (2010). Fibronectin activity on substrates with controlled -OH density Journal of Biomedical Materials Research - Part A 92A, (1), 322-331

Krasteva, N. A., Toromanov, G., Hristova, K. T., Radeva, E. I., Pecheva, E. V., Dimitrova, R. P., Altankov, G. P., Pramatarova, L. D., (2010). Initial biocompatibility of plasma polymerized hexamethyldisiloxane films with different wettability Journal of Physics: Conference Series IOP Publishing Ltd. 253, (1), 012079 (7 pp.)

Pramatarova, L. D., Krasteva, N. A., Radeva, E. I., Pecheva, E. V., Dimitrova, R. P., Hikov, T. A., Mitev, D. P., Hristova, K. T., Altankov, G., (2010). Study of detonation nanodiamond - Plasma polymerized hexamethildisiloxan composites for medical application Journal of Physics: Conference Series IOP Publishing Ltd. 253, (1), 012078 (7 pp.)

Salmeron-Sanchez, M., Altankov, G., (2010). Cell-Protein-Material interaction in tissue engineering Intech , 77-102

Altankov, George, Groth, Thomas, Engel, Elisabeth, Gustavsson, Jonas, Pegueroles, Marta, Aparicio, Conrado, Gil, Francesc J., Ginebra, Maria-Pau, Planell, Josep A., (2010). Development of provisional extracellular matrix on biomaterials interface: Lessons from in vitro cell culture NATO Science for Peace and Security Series A: Chemistry and Biology Springer Netherlands , 19-43

Planell, Josep A., Navarro, Melba, Altankov, George, Aparicio, Conrado, Engel, Elisabeth, Gil, Javier, Ginebra, Maria Pau, Lacroix, Damien, (2010). Materials surface effects on biological interactions NATO Science for Peace and Security Series A: Chemistry and Biology Springer Netherlands , 233-252

Gugutkov, Dencho, Gonzalez-Garcia, Cristina, Rodriguez Hernandez, Jose Carlos, Altankov, George, Salmeron-Sanchez, Manuel, (2009). Biological activity of the substrate-induced fibronectin network: insight into the third dimension through electrospun fibers Langmuir 25, (18), 10893-10900

Kostadinova, A., Seifert, B., Albrecht, W., Malsch, G., Groth, T., Lendlein, A., Altankov, G., (2009). Novel polymer blends for the preparation of membranes for biohybrid liver systems Journal of Biomaterials Science, Polymer Edition 20, (5-6), 821-839

Rico, P., Rodriguez Hernandez, J. C., Moratal, D., Altankov, G., Monleon Pradas, M., Salmeron-Sanchez, M., (2009). Substrate-induced assembly of fibronectin into networks. Influence of surface chemistry and effect on osteoblast adhesion Tissue Engineering Part A 15, (00), 1-11

Kirchhof, K., Hristova, K., Krasteva, N., Altankov, G., Groth, T., (2009). Multilayer coatings on biomaterials for control of MG-63 osteoblast adhesion and growth Journal of Materials Science: Materials in Medicine 20, (4), 897-907

Engel, E., Del Valle, S., Aparicio, C., Altankov, G., Asin, L., Planell, J. A., Ginebra, M. P., (2008). Discerning the role of topography and ion exchange in cell response of bioactive tissue engineering scaffolds Tissue Engineering Part A 14, (8), 1341-1351

Maneva-Radicheva, L., Ebert, U., Dimoudis, N., Altankov, G., (2008). Fibroblast remodeling of adsorbed collagen type IV is altered in contact with cancer cells Histology and Histopathology 23, (7), 833-842

Manara, S., Paolucci, F., Palazzo, B., Marcaccio, M., Foresti, E., Tosi, G., Sabbatini, S., Sabatino, P., Altankov, G., Roveri, N., (2008). Electrochemically-assisted deposition of biomimetic hydroxyapatite-collagen coatings on titanium plate Inorganica Chimica Acta 361, (6), 1634-1645

Gustavsson, J., Altankov, G., Errachid, A., Samitier, J., Planell, J. A., Engel, E., (2008). Surface modifications of silicon nitride for cellular biosensor applications Journal of Materials Science-Materials in Medicine 19, (4), 1839-1850

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