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X-ORIGINAL-URL:https://ibecbarcelona.eu/ca/
X-WR-CALDESC:Esdeveniments per Institute for Bioengineering of Catalonia
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DTSTART:20150101T000000
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BEGIN:VEVENT
DTSTART;TZID=UTC:20160311T100000
DTEND;TZID=UTC:20160311T110000
DTSTAMP:20260506T033617
CREATED:20160229T091313Z
LAST-MODIFIED:20160229T091313Z
UID:21728-1457690400-1457694000@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Samuel Ojosnegros
DESCRIPTION:Imaging Eph/ephrin cell-cell communication through Enhanced Number and Brightness: a novel method for the study of protein aggregation\nDr. Samuel Ojosnegros\, Centre de Medicina Regenerativa de Barcelona (CMRB)\nProteins constantly interact with each other assembling a variety of molecular species\, including small oligomers\, fibers of dynamic polymerization or high-order clusters\, among others. However\, current methods discriminate poorly the stoichiometry of protein interactions in living cells. To overcome these impediments we developed an enhanced version of Number & Brightness (eN&B)\, a powerful live imaging technique with capability to investigate multiple domains of information.  eN&B determines the distribution of protein aggregates present inside every pixel in an image during time-lapse movies. It can reach unprecedented level of space and time resolution compared to FRET-based or FCS-based methods. When studying EphB2 receptor activation\, the eN&B allowed us to resolve simultaneously the aggregation state of 40 different oligomers in 3 dimensions (x\, y\, t) and pixel depth. We found that Eph oligomerization follows a sophisticated dynamics consistent with a nucleated polymerization process\, where activation and clustering are decoupled processes. This decoupling endows the receptor with high sensitivity for low ligand concentrations while at the same time allows to provide a proportional response to a wide range of ligand concentrations. In summary\, I will present a novel imaging tool with capability to determine the stoichiometry of receptor-ligand interactions and potentially\, many other instances or protein aggregation.
URL:https://ibecbarcelona.eu/ca/event/ibec-seminar-samuel-ojosnegros/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20160311T100000
DTEND;TZID=UTC:20160311T110000
DTSTAMP:20260506T033617
CREATED:20160229T091313Z
LAST-MODIFIED:20160229T091313Z
UID:95898-1457690400-1457694000@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Samuel Ojosnegros
DESCRIPTION:Imaging Eph/ephrin cell-cell communication through Enhanced Number and Brightness: a novel method for the study of protein aggregation\nDr. Samuel Ojosnegros\, Centre de Medicina Regenerativa de Barcelona (CMRB)\nProteins constantly interact with each other assembling a variety of molecular species\, including small oligomers\, fibers of dynamic polymerization or high-order clusters\, among others. However\, current methods discriminate poorly the stoichiometry of protein interactions in living cells. To overcome these impediments we developed an enhanced version of Number & Brightness (eN&B)\, a powerful live imaging technique with capability to investigate multiple domains of information.  eN&B determines the distribution of protein aggregates present inside every pixel in an image during time-lapse movies. It can reach unprecedented level of space and time resolution compared to FRET-based or FCS-based methods. When studying EphB2 receptor activation\, the eN&B allowed us to resolve simultaneously the aggregation state of 40 different oligomers in 3 dimensions (x\, y\, t) and pixel depth. We found that Eph oligomerization follows a sophisticated dynamics consistent with a nucleated polymerization process\, where activation and clustering are decoupled processes. This decoupling endows the receptor with high sensitivity for low ligand concentrations while at the same time allows to provide a proportional response to a wide range of ligand concentrations. In summary\, I will present a novel imaging tool with capability to determine the stoichiometry of receptor-ligand interactions and potentially\, many other instances or protein aggregation.
URL:https://ibecbarcelona.eu/ca/event/ibec-seminar-samuel-ojosnegros-2/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20160315T080000
DTEND;TZID=UTC:20160316T170000
DTSTAMP:20260506T033617
CREATED:20160311T103533Z
LAST-MODIFIED:20170801T130622Z
UID:21844-1458028800-1458147600@ibecbarcelona.eu
SUMMARY:IX Conferencia Anual de las Plataformas Tecnológicas de Investigación Biomédica
DESCRIPTION:En esta Conferencia Anual\, se persigue dar respuesta a los nuevos retos que se plantean en la investigación biomédica. Algunos\, llegan de la mano de un nuevo marco normativo como el Real Decreto 1090/2015 de Ensayos Clínicos\, que supone un cambio significativo en el país y permitirá una adaptación rápida y competitiva a las nuevas exigencias cuando entre en vigor el nuevo Reglamento Europeo sobre la materia. Además\, se tratarán de resolver otros retos\, como la  reutilización de datos para la investigación biomédica\, salvaguardando las cuestiones éticas y legales\, al mismo tiempo que se permite el avance científico. Todo ello desde una perspectiva nacional e internacional de colaboración público-privada. \nAgenda
URL:https://ibecbarcelona.eu/ca/event/ix-conferencia-anual-de-las-plataformas-tecnologicas-de-investigacion-biomedica/
LOCATION:Hotel Crowne Plaza\, Avinguda de Rius i Taulet 1-3\, Barcelona\, Spain
CATEGORIES:External symposium / conference / congress
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20160315T080000
DTEND;TZID=UTC:20160316T170000
DTSTAMP:20260506T033617
CREATED:20160311T103533Z
LAST-MODIFIED:20160311T103533Z
UID:95900-1458028800-1458147600@ibecbarcelona.eu
SUMMARY:IX Conferencia Anual de las Plataformas Tecnológicas de Investigación Biomédica
DESCRIPTION:En esta Conferencia Anual\, se persigue dar respuesta a los nuevos retos que se plantean en la investigación biomédica. Algunos\, llegan de la mano de un nuevo marco normativo como el Real Decreto 1090/2015 de Ensayos Clínicos\, que supone un cambio significativo en el país y permitirá una adaptación rápida y competitiva a las nuevas exigencias cuando entre en vigor el nuevo Reglamento Europeo sobre la materia. Además\, se tratarán de resolver otros retos\, como la  reutilización de datos para la investigación biomédica\, salvaguardando las cuestiones éticas y legales\, al mismo tiempo que se permite el avance científico. Todo ello desde una perspectiva nacional e internacional de colaboración público-privada. \nAgenda
URL:https://ibecbarcelona.eu/ca/event/ix-conferencia-anual-de-las-plataformas-tecnologicas-de-investigacion-biomedica-2/
LOCATION:Hotel Crowne Plaza\, Avinguda de Rius i Taulet 1-3\, Barcelona\, Spain
CATEGORIES:External symposium / conference / congress
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20160318T100000
DTEND;TZID=UTC:20160318T110000
DTSTAMP:20260506T033617
CREATED:20160229T090903Z
LAST-MODIFIED:20160311T103315Z
UID:21726-1458295200-1458298800@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Mateu Pla
DESCRIPTION:What can we do with our 3D Bioprinter?\nDr. Mateu Pla\, Coordinator of Nanotechnology Platform\nA 3D bioprinter (3D-Discovery from RegenHU ) has recently arrived at IBEC\, and the first training courses have already started. \n3D Bioprinters allow us to generate 3D scaffolds combining biomaterials and cell-laden hydrogels. The applications of this 3D constructs spans from 3D cellular models for drug screening (i.e. dermis)\, scaffolds for regenerative medicine or\, at a more advanced stage\, organ-printing. \nDuring this presentation\, an introduction to bioprinting and the current and future capabilities of IBEC’s 3D bioprinter will be presented.
URL:https://ibecbarcelona.eu/ca/event/ibec-seminar-mateu-pla/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20160318T100000
DTEND;TZID=UTC:20160318T110000
DTSTAMP:20260506T033617
CREATED:20160229T090903Z
LAST-MODIFIED:20160229T090903Z
UID:95897-1458295200-1458298800@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Mateu Pla
DESCRIPTION:What can we do with our 3D Bioprinter?\nDr. Mateu Pla\, Coordinator of Nanotechnology Platform\nA 3D bioprinter (3D-Discovery from RegenHU ) has recently arrived at IBEC\, and the first training courses have already started. \n3D Bioprinters allow us to generate 3D scaffolds combining biomaterials and cell-laden hydrogels. The applications of this 3D constructs spans from 3D cellular models for drug screening (i.e. dermis)\, scaffolds for regenerative medicine or\, at a more advanced stage\, organ-printing. \nDuring this presentation\, an introduction to bioprinting and the current and future capabilities of IBEC’s 3D bioprinter will be presented.
URL:https://ibecbarcelona.eu/ca/event/ibec-seminar-mateu-pla-2/
CATEGORIES:IBEC Seminar
END:VEVENT
END:VCALENDAR