{"id":71336,"date":"2020-02-12T11:50:06","date_gmt":"2020-02-12T10:50:06","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?page_id=71336"},"modified":"2020-02-12T11:50:46","modified_gmt":"2020-02-12T10:50:46","slug":"big-data-methods-for-electric-functional-scanning-probe-microscopies-in-biology","status":"publish","type":"page","link":"https:\/\/ibecbarcelona.eu\/for-students\/doing-your-phd\/ibec-international-phd-programme\/big-data-methods-for-electric-functional-scanning-probe-microscopies-in-biology\/","title":{"rendered":"Big data methods for electric functional scanning probe microscopies in Biology"},"content":{"rendered":"<p><em>Group: Nanoscale bioelectric characterization<br \/>\n<\/em><em>Grou<\/em>p leader: Gabriel Gomila (ggomila@ibecbarcelona.eu)<\/p>\n<p>The passive electrical properties of biological systems, such as the electric charge, conductivity or electrical polarization play a fundamental role in several physiological processes such as cellular communication, adherence to surfaces, internalization of nutrients, molecules or particles and cellular growth. Due to this relevance, several techniques have been developed along the years to probe the electrical properties in biological systems. However, in most cases, these techniques only provide a spatial resolution in the micrometer range, what does not allow accessing the very local electrical properties at the nanoscale, which are fundamental in most electrophysiological phenomena. To address these properties at this scale specific innovative methods are required to acquire, process and analyze huge volume of data. The objective of the present project is to develop big data methods, including machine learning methods, adapted to electric scanning probe microscopes, to produce the first electrical functional images of living cells at high spatial resolution (sub-100 nm).<\/p>\n<p><em> <img decoding=\"async\" class=\"size-full wp-image-71337 alignleft lazyload\" data-src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/02\/ggomila.png\" alt=\"\" width=\"431\" height=\"306\" data-srcset=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/02\/ggomila.png 431w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/02\/ggomila-300x213.png 300w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/02\/ggomila-150x106.png 150w\" data-sizes=\"(max-width: 431px) 100vw, 431px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 431px; --smush-placeholder-aspect-ratio: 431\/306;\" \/><\/em><\/p>\n<p><em>Checa, Marti, Mill\u00e1n, Rub\u00e9n, Blanco, N\u00faria, Torrents, Eduard, Fabregas, Rene, Gomila, Gabriel, (2019).\u00a0<a href=\"http:\/\/dx.doi.org\/10.1039\/C9NR07659J\">Mapping the dielectric constant of a single bacterial cell at the nanoscale with scanning dielectric force volume microscopy<\/a>\u00a0Nanoscale\u00a011, 20809-20819<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Group: Nanoscale bioelectric characterization Group leader: Gabriel Gomila (ggomila@ibecbarcelona.eu) The passive electrical properties of biological systems, such as the electric charge, conductivity or electrical polarization play a fundamental role in &#8230; <a title=\"Big data methods for electric functional scanning probe microscopies in Biology\" class=\"read-more\" href=\"https:\/\/ibecbarcelona.eu\/for-students\/doing-your-phd\/ibec-international-phd-programme\/big-data-methods-for-electric-functional-scanning-probe-microscopies-in-biology\/\" aria-label=\"More on Big data methods for electric functional scanning probe microscopies in Biology\">Read more<\/a><\/p>\n","protected":false},"author":4,"featured_media":0,"parent":24978,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"tags":[],"class_list":["post-71336","page","type-page","status-publish"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Big data methods for electric functional scanning probe microscopies in Biology - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/for-students\/doing-your-phd\/ibec-international-phd-programme\/big-data-methods-for-electric-functional-scanning-probe-microscopies-in-biology\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Big data methods for electric functional scanning probe microscopies in Biology - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Group: Nanoscale bioelectric characterization Group leader: Gabriel Gomila (ggomila@ibecbarcelona.eu) The passive electrical properties of biological systems, such as the electric charge, conductivity or electrical polarization play a fundamental role in ... 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