{"id":103053,"date":"2022-12-22T17:08:50","date_gmt":"2022-12-22T16:08:50","guid":{"rendered":"https:\/\/ibecbarcelona.eu\/?p=103053"},"modified":"2022-12-22T17:45:57","modified_gmt":"2022-12-22T16:45:57","slug":"nanoscale-discovery-reveals-how-phosphorylation-affects-electron-transport-in-mitochondria","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris","title":{"rendered":"Descobriment nanosc\u00f2pic revela com la fosforilaci\u00f3 afecta al transport d’electrons en els mitocondris"},"content":{"rendered":"\n

Investigadors de l’Institut de Bioenginyeria de Catalunya (IBEC) i del CIBER-BBN, han aconseguit obtenir una visi\u00f3 nanosc\u00f2pica de la transfer\u00e8ncia d’electrons que t\u00e9 lloc dins dels mitocondris, la qual cosa permet entendre millor el proc\u00e9s de regulaci\u00f3 de la respiraci\u00f3 cel\u00b7lular. El treball, liderat per les investigadores de l’IBEC Anna Lagunas i Marina I. Giannotti, s\u2019ha publicat en la revista cient\u00edfica Nature Communications i obre noves possibilitats en la recerca d’aquesta important funci\u00f3 biol\u00f2gica.\u00a0<\/h4>\n\n\n\n
\"\"
Marina I. Giannotti i Anna Lagunas (d’esquerra a dreta)<\/figcaption><\/figure>\n\n\n\n

Els mitocondris, coneguts com el motor de les c\u00e8l\u00b7lules pel seu paper en la producci\u00f3 d’energia, s\u00f3n org\u00e0nuls units a la membrana que es troben en gaireb\u00e9 totes les c\u00e8l\u00b7lules eucariotes (animals, plantes i fongs). La seva funci\u00f3 principal en les c\u00e8l\u00b7lules animals \u00e9s convertir els nutrients en energia qu\u00edmica, emmagatzemada en forma de mol\u00e8cules de trifosfat d’adenosina (ATP), a trav\u00e9s de l’anomenada respiraci\u00f3 cel\u00b7lular, que inclou un proc\u00e9s altament regulat de transport d’electrons entre prote\u00efnes. A m\u00e9s d’aquesta funci\u00f3, els mitocondris tamb\u00e9 s\u00f3n responsables d’altres funcions, com la inducci\u00f3 de la mort cel\u00b7lular en resposta a esdeveniments estressants. La disfunci\u00f3 dels mitocondris s’ha relacionat amb una s\u00e8rie de malalties, com la dem\u00e8ncia i les malalties card\u00edaques. <\/p>\n\n\n\n

Un nou estudi liderat per l’Institut de Bioenginyeria de Catalunya (IBEC) ha utilitzat t\u00e8cniques nanosc\u00f2piques d’avantguarda per a obtenir una visi\u00f3 sense precedents de la regulaci\u00f3 del transport d’electrons entre les prote\u00efnes que impulsen els processos mitocondrials. Aquest treball ha demostrat que la fosforilaci\u00f3, el proc\u00e9s mitjan\u00e7ant el qual s’afegeix un grup fosfato i que permet l’ajust de la funci\u00f3 de prote\u00efnes, afecta tamb\u00e9 al transport d’electrons en la cadena respirat\u00f2ria mitocondrial. A causa de l’important paper que exerceix aquest org\u00e0nul cel\u00b7lular tant en els estats de salut com de malaltia, aquest estudi \u00e9s clau per a la comprensi\u00f3 de la funci\u00f3 d’aquesta estructura a nivell molecular. <\/p>\n\n\n\n

L’estudi, publicat recentment en la revista Nature Communications, ha estat realitzat per Anna Lagunas, investigadora s\u00e8nior del grup de Nanobioenginyeria de l’IBEC liderat per Josep Samitier, i Marina I. Giannotti, investigadora s\u00e8nior del grup de Nanosondes i Nanocommutadors de l’IBEC liderat per Pau Gorostiza. Ambdues s\u00f3n investigadores del CIBBER-BBN. En aquest estudi tamb\u00e9 han contribu\u00eft els investigadors de l’IBEC Alexandre M. J. Gomila, Laura Casas-Ferrer i Sthefany Ortiz-Tescari, aix\u00ed com els equips de recerca de la Prof. Irene D\u00edaz-Moreno de l’Institut de Recerques Qu\u00edmiques (IIQ-cicCartuja, Universitat de Sevilla-CSIC) i de la Prof. Carme Rovira de l’Institut de Qu\u00edmica Te\u00f2rica i Computacional de la Universitat de Barcelona. <\/p>\n\n\n\n

Regulaci\u00f3 del transport d\u2019electrons<\/strong> <\/p>\n\n\n\n

La respiraci\u00f3 cel\u00b7lular \u00e9s el proc\u00e9s mitjan\u00e7ant el qual les c\u00e8l\u00b7lules converteixen els nutrients en energia qu\u00edmica i alliberen productes de deixalla. Aquest proc\u00e9s t\u00e9 lloc mitjan\u00e7ant un conjunt de reaccions bioqu\u00edmiques, algunes de les quals s\u00f3n reaccions redox, que impliquen la transfer\u00e8ncia d’electrons entre prote\u00efnes. En els mitocondris, el citocrom c i el citocrom bc1 s\u00f3n dos de les prote\u00efnes que participen en aquest proc\u00e9s. Un estudi anterior realitzat per Anna Lagunas i liderat per Pau Gorostiza de l’IBEC va demostrar que aquestes dues prote\u00efnes poden transferir electrons a una certa dist\u00e0ncia a trav\u00e9s d’un conducte de c\u00e0rrega que s’estableix entre elles, la qual cosa implica que no \u00e9s necess\u00e0ria la formaci\u00f3 d’un complex fortament unit en el reconeixement molecular, permetent aix\u00ed mantenir l’especificitat en un proc\u00e9s que ha de ser altament eficient. \u201cEn aquest nou estudi, vol\u00edem comprendre millor com la fosforilaci\u00f3 regula aquest proc\u00e9s\u201d, comenta Giannotti. <\/p>\n\n\n\n

Aquest treball combina l’an\u00e0lisi del transport d’electrons a nivell molecular amb la mesura de les forces d’interacci\u00f3 entre prote\u00efnes, la qual cosa ha perm\u00e8s als investigadors comprendre millor els efectes de la fosforilaci\u00f3 del citocrom c en la regulaci\u00f3 molecular de la cadena respirat\u00f2ria mitocondrial. S’ha descobert que la fosforilaci\u00f3 altera el transport d’electrons bloquejant el conducte de c\u00e0rrega i augmentant l’afinitat entre citocrom c i citocrom c1, la qual cosa donaria lloc a la formaci\u00f3 de colls d’ampolla en el proc\u00e9s alentint el flux d’electrons en la cadena. <\/p>\n\n\n\n

\n

\u201cLa fosforilaci\u00f3 del citocrom c exerceix un paper crucial en la regulaci\u00f3 de la respiraci\u00f3 mitocondrial i en el metabolisme cel\u00b7lular en general\u201d, explica Lagunas. <\/p>\n<\/blockquote>\n\n\n\n

\u201cNosaltres observem que, a causa de la fosforilaci\u00f3, el conducte de c\u00e0rrega entre citocrom c i citocrom c1 es desorganitza i la interacci\u00f3 entre totes dues prote\u00efnes es refor\u00e7a i s’allunya de l’equilibri d’uni\u00f3\/desuni\u00f3 en les condicions de l’experiment. Aix\u00f2 altera la via de difusi\u00f3 de les mol\u00e8cules de citocrom c, alentint el proc\u00e9s i afectant per tant el flux d’electrons en la cadena respirat\u00f2ria, alentint la respiraci\u00f3 mitocondrial\u201d.\u00a0<\/p>\n\n\n\n

Encara que aquest estudi es va centrar en dues prote\u00efnes espec\u00edfiques, el citocrom c i el citocrom c1, el mecanisme de regulaci\u00f3 descobert podria aplicar-se a altres prote\u00efnes involucrades en processos de transfer\u00e8ncia electr\u00f2nica, aix\u00ed com a altres funcions biol\u00f2giques i tipus de regulaci\u00f3 mitjan\u00e7ant fosforilaci\u00f3. \u201cAquest \u00e9s el primer estudi que mesura tant la for\u00e7a de la interacci\u00f3 com el transport de c\u00e0rrega entre aquestes dues prote\u00efnes a\u00efllades; en combinar totes dues mesures, hem aconseguit una visi\u00f3 nanosc\u00f2pica de la interacci\u00f3 entre prote\u00efnes en les cadenes de transport d’electrons i els seus mecanismes de regulaci\u00f3”, conclou Giannotti.\u00a0<\/em><\/p>\n\n\n\n

Reference article:<\/strong><\/p>\n\n\n\n

Alexandre M. J. Gomila, Gonzalo P\u00e9rez-Mej\u00edas, Alba Nin-Hill, Alejandra Guerra-Castellano, Laura Casas-Ferrer, Sthefany Ortiz-Tescari, Antonio D\u00edaz-Quintana, Josep Samitier, Carme Rovira, Miguel A. De la Rosa, Irene D\u00edaz-Moreno, Pau Gorostiza, Marina I. Giannotti & Anna Lagunas. Phosphorylation disrupts long-distance electron transport in cytochrome c<\/a>. <\/em>Nature Communications, volume 13, Article number: 7100 (2022)<\/em><\/strong> <\/p>\n","protected":false},"excerpt":{"rendered":"

Investigadors de l’Institut de Bioenginyeria de Catalunya (IBEC) i del CIBER-BBN, han aconseguit obtenir una visi\u00f3 nanosc\u00f2pica de la transfer\u00e8ncia d’electrons que t\u00e9 lloc dins dels mitocondris, la qual cosa … Read more<\/a><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96],"tags":[1877,1878,1879],"post_formats":[],"class_list":["post-103053","post","type-post","status-publish","format-standard","hentry","category-noticies-de-recerca","tag-mitochondria-ca","tag-nanobioengineering-ca","tag-nanoprobes-and-nanoswitches-ca"],"yoast_head":"\nDescobriment nanosc\u00f2pic revela com la fosforilaci\u00f3 afecta al transport d'electrons en els mitocondris - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/com-la-fosforilacio-afecta-al-transport-d'electrons-en-els-mitocondris\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Descobriment nanosc\u00f2pic revela com la fosforilaci\u00f3 afecta al transport d'electrons en els mitocondris - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Investigadors de l’Institut de Bioenginyeria de Catalunya (IBEC) i del CIBER-BBN, han aconseguit obtenir una visi\u00f3 nanosc\u00f2pica de la transfer\u00e8ncia d’electrons que t\u00e9 lloc dins dels mitocondris, la qual cosa ... Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ibecbarcelona.eu\/ca\/com-la-fosforilacio-afecta-al-transport-d'electrons-en-els-mitocondris\/\" \/>\n<meta property=\"og:site_name\" content=\"Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"article:published_time\" content=\"2022-12-22T16:08:50+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-12-22T16:45:57+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/12\/Gianotti_lagunas_web-1024x715.jpg\" \/>\n<meta name=\"author\" content=\"\u00c0ngels L\u00f3pez\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrit per\" \/>\n\t<meta name=\"twitter:data1\" content=\"\u00c0ngels L\u00f3pez\" \/>\n\t<meta name=\"twitter:label2\" content=\"Temps estimat de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minuts\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\\\/\"},\"author\":{\"name\":\"\u00c0ngels L\u00f3pez\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/person\\\/c212c6b589546130be67986b9290e2b8\"},\"headline\":\"Descobriment nanosc\u00f2pic revela com la fosforilaci\u00f3 afecta al transport d’electrons en els mitocondris\",\"datePublished\":\"2022-12-22T16:08:50+00:00\",\"dateModified\":\"2022-12-22T16:45:57+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\\\/\"},\"wordCount\":1016,\"publisher\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2022\\\/12\\\/Gianotti_lagunas_web-1024x715.jpg\",\"keywords\":[\"Mitochondria\",\"Nanobioengineering\",\"Nanoprobes and nanoswitches\"],\"articleSection\":[\"Not\u00edcies de recerca\"],\"inLanguage\":\"ca\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\\\/\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\\\/\",\"name\":\"Descobriment nanosc\u00f2pic revela com la fosforilaci\u00f3 afecta al transport d'electrons en els mitocondris - Institute for Bioengineering of Catalonia\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2022\\\/12\\\/Gianotti_lagunas_web-1024x715.jpg\",\"datePublished\":\"2022-12-22T16:08:50+00:00\",\"dateModified\":\"2022-12-22T16:45:57+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\\\/#breadcrumb\"},\"inLanguage\":\"ca\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"ca\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\\\/#primaryimage\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2022\\\/12\\\/Gianotti_lagunas_web-1024x715.jpg\",\"contentUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2022\\\/12\\\/Gianotti_lagunas_web-1024x715.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Descobriment nanosc\u00f2pic revela com la fosforilaci\u00f3 afecta al transport d’electrons en els mitocondris\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#website\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/\",\"name\":\"Institute for Bioengineering of Catalonia\",\"description\":\"Bioengineering Solutions for Health\",\"publisher\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/ibecbarcelona.eu\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"ca\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#organization\",\"name\":\"Institute for Bioengineering of Catalonia\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"ca\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2026\\\/01\\\/cropped-IBEC_20ANYS_GRIS.png\",\"contentUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2026\\\/01\\\/cropped-IBEC_20ANYS_GRIS.png\",\"width\":696,\"height\":257,\"caption\":\"Institute for Bioengineering of Catalonia\"},\"image\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/person\\\/c212c6b589546130be67986b9290e2b8\",\"name\":\"\u00c0ngels L\u00f3pez\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"ca\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/09ad6ba116bea0b15c5511860f83b302579fd7404c1180e9dae55c3f11d988c6?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/09ad6ba116bea0b15c5511860f83b302579fd7404c1180e9dae55c3f11d988c6?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/09ad6ba116bea0b15c5511860f83b302579fd7404c1180e9dae55c3f11d988c6?s=96&d=mm&r=g\",\"caption\":\"\u00c0ngels L\u00f3pez\"},\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/author\\\/alopez\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Descobriment nanosc\u00f2pic revela com la fosforilaci\u00f3 afecta al transport d'electrons en els mitocondris - Institute for Bioengineering of Catalonia","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/ibecbarcelona.eu\/ca\/com-la-fosforilacio-afecta-al-transport-d'electrons-en-els-mitocondris\/","og_locale":"ca_ES","og_type":"article","og_title":"Descobriment nanosc\u00f2pic revela com la fosforilaci\u00f3 afecta al transport d'electrons en els mitocondris - Institute for Bioengineering of Catalonia","og_description":"Investigadors de l’Institut de Bioenginyeria de Catalunya (IBEC) i del CIBER-BBN, han aconseguit obtenir una visi\u00f3 nanosc\u00f2pica de la transfer\u00e8ncia d’electrons que t\u00e9 lloc dins dels mitocondris, la qual cosa ... Read more","og_url":"https:\/\/ibecbarcelona.eu\/ca\/com-la-fosforilacio-afecta-al-transport-d'electrons-en-els-mitocondris\/","og_site_name":"Institute for Bioengineering of Catalonia","article_published_time":"2022-12-22T16:08:50+00:00","article_modified_time":"2022-12-22T16:45:57+00:00","og_image":[{"url":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/12\/Gianotti_lagunas_web-1024x715.jpg","type":"","width":"","height":""}],"author":"\u00c0ngels L\u00f3pez","twitter_card":"summary_large_image","twitter_misc":{"Escrit per":"\u00c0ngels L\u00f3pez","Temps estimat de lectura":"5 minuts"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/ibecbarcelona.eu\/ca\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\/#article","isPartOf":{"@id":"https:\/\/ibecbarcelona.eu\/ca\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\/"},"author":{"name":"\u00c0ngels L\u00f3pez","@id":"https:\/\/ibecbarcelona.eu\/#\/schema\/person\/c212c6b589546130be67986b9290e2b8"},"headline":"Descobriment nanosc\u00f2pic revela com la fosforilaci\u00f3 afecta al transport d’electrons en els mitocondris","datePublished":"2022-12-22T16:08:50+00:00","dateModified":"2022-12-22T16:45:57+00:00","mainEntityOfPage":{"@id":"https:\/\/ibecbarcelona.eu\/ca\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\/"},"wordCount":1016,"publisher":{"@id":"https:\/\/ibecbarcelona.eu\/#organization"},"image":{"@id":"https:\/\/ibecbarcelona.eu\/ca\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\/#primaryimage"},"thumbnailUrl":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/12\/Gianotti_lagunas_web-1024x715.jpg","keywords":["Mitochondria","Nanobioengineering","Nanoprobes and nanoswitches"],"articleSection":["Not\u00edcies de recerca"],"inLanguage":"ca"},{"@type":"WebPage","@id":"https:\/\/ibecbarcelona.eu\/ca\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\/","url":"https:\/\/ibecbarcelona.eu\/ca\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\/","name":"Descobriment nanosc\u00f2pic revela com la fosforilaci\u00f3 afecta al transport d'electrons en els mitocondris - Institute for Bioengineering of Catalonia","isPartOf":{"@id":"https:\/\/ibecbarcelona.eu\/#website"},"primaryImageOfPage":{"@id":"https:\/\/ibecbarcelona.eu\/ca\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\/#primaryimage"},"image":{"@id":"https:\/\/ibecbarcelona.eu\/ca\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\/#primaryimage"},"thumbnailUrl":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/12\/Gianotti_lagunas_web-1024x715.jpg","datePublished":"2022-12-22T16:08:50+00:00","dateModified":"2022-12-22T16:45:57+00:00","breadcrumb":{"@id":"https:\/\/ibecbarcelona.eu\/ca\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\/#breadcrumb"},"inLanguage":"ca","potentialAction":[{"@type":"ReadAction","target":["https:\/\/ibecbarcelona.eu\/ca\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\/"]}]},{"@type":"ImageObject","inLanguage":"ca","@id":"https:\/\/ibecbarcelona.eu\/ca\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\/#primaryimage","url":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/12\/Gianotti_lagunas_web-1024x715.jpg","contentUrl":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/12\/Gianotti_lagunas_web-1024x715.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/ibecbarcelona.eu\/ca\/com-la-fosforilacio-afecta-al-transport-d%27electrons-en-els-mitocondris\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/ibecbarcelona.eu\/ca\/"},{"@type":"ListItem","position":2,"name":"Descobriment nanosc\u00f2pic revela com la fosforilaci\u00f3 afecta al transport d’electrons en els mitocondris"}]},{"@type":"WebSite","@id":"https:\/\/ibecbarcelona.eu\/#website","url":"https:\/\/ibecbarcelona.eu\/","name":"Institute for Bioengineering of Catalonia","description":"Bioengineering Solutions for Health","publisher":{"@id":"https:\/\/ibecbarcelona.eu\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/ibecbarcelona.eu\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"ca"},{"@type":"Organization","@id":"https:\/\/ibecbarcelona.eu\/#organization","name":"Institute for Bioengineering of Catalonia","url":"https:\/\/ibecbarcelona.eu\/","logo":{"@type":"ImageObject","inLanguage":"ca","@id":"https:\/\/ibecbarcelona.eu\/#\/schema\/logo\/image\/","url":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/01\/cropped-IBEC_20ANYS_GRIS.png","contentUrl":"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/01\/cropped-IBEC_20ANYS_GRIS.png","width":696,"height":257,"caption":"Institute for Bioengineering of Catalonia"},"image":{"@id":"https:\/\/ibecbarcelona.eu\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/ibecbarcelona.eu\/#\/schema\/person\/c212c6b589546130be67986b9290e2b8","name":"\u00c0ngels L\u00f3pez","image":{"@type":"ImageObject","inLanguage":"ca","@id":"https:\/\/secure.gravatar.com\/avatar\/09ad6ba116bea0b15c5511860f83b302579fd7404c1180e9dae55c3f11d988c6?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/09ad6ba116bea0b15c5511860f83b302579fd7404c1180e9dae55c3f11d988c6?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/09ad6ba116bea0b15c5511860f83b302579fd7404c1180e9dae55c3f11d988c6?s=96&d=mm&r=g","caption":"\u00c0ngels L\u00f3pez"},"url":"https:\/\/ibecbarcelona.eu\/ca\/author\/alopez\/"}]}},"AFP_featured_media_urls":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false},"AFP_attachments":{"full":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/12\/Gianotti_lagunas_web.jpg",1200,838,false],"thumbnail":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/12\/Gianotti_lagunas_web-150x150.jpg",150,150,true],"medium":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/12\/Gianotti_lagunas_web-300x210.jpg",300,210,true],"medium_large":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/12\/Gianotti_lagunas_web-768x536.jpg",768,536,true],"large":["https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/12\/Gianotti_lagunas_web-1024x715.jpg",1024,715,true]},"AFP_videos":[],"AFP_video_blocks":"","AFP_category_names":["Not\u00edcies de recerca"],"_links":{"self":[{"href":"https:\/\/ibecbarcelona.eu\/ca\/wp-json\/wp\/v2\/posts\/103053","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ibecbarcelona.eu\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ibecbarcelona.eu\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ibecbarcelona.eu\/ca\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/ibecbarcelona.eu\/ca\/wp-json\/wp\/v2\/comments?post=103053"}],"version-history":[{"count":10,"href":"https:\/\/ibecbarcelona.eu\/ca\/wp-json\/wp\/v2\/posts\/103053\/revisions"}],"predecessor-version":[{"id":103075,"href":"https:\/\/ibecbarcelona.eu\/ca\/wp-json\/wp\/v2\/posts\/103053\/revisions\/103075"}],"wp:attachment":[{"href":"https:\/\/ibecbarcelona.eu\/ca\/wp-json\/wp\/v2\/media?parent=103053"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ibecbarcelona.eu\/ca\/wp-json\/wp\/v2\/categories?post=103053"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ibecbarcelona.eu\/ca\/wp-json\/wp\/v2\/tags?post=103053"},{"taxonomy":"post_format","embeddable":true,"href":"https:\/\/ibecbarcelona.eu\/ca\/wp-json\/wp\/v2\/post_formats?post=103053"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}