{"id":119322,"date":"2024-07-11T12:00:00","date_gmt":"2024-07-11T10:00:00","guid":{"rendered":"https:\/\/ibecbarcelona.eu\/?p=119322"},"modified":"2024-07-11T16:04:16","modified_gmt":"2024-07-11T14:04:16","slug":"nanorobots-capable-of-travelling-through-synovial-fluid-to-fight-arthritis","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/nanorobots-capacos-de-travessar-els-fluids-articulars-per-combatre-artritis","title":{"rendered":"Nanorobots capa\u00e7os de travessar els fluids articulars per combatre l’artritis"},"content":{"rendered":"\n

Samuel S\u00e1nchez, professor de recerca ICREA a l’Institut de Bioenginyeria de Catalunya (IBEC) liderar\u00e0 el projecte OrthoBots enfocat en el tractament de malalties articulars mitjan\u00e7ant l’\u00fas de nanorobots. Per dur a terme el projecte, S\u00e1nchez ha estat guardonat amb una “ERC Proof of Concept Grant”, una prestigiosa subvenci\u00f3 que concedeix el Consell Europeu d’Investigaci\u00f3.<\/strong><\/strong><\/p>\n\n\n\n

\"Samuel<\/figure>\n\n\n\n
<\/div>\n\n\n\n

Samuel S\u00e1nchez, professor de recerca ICREA a l’Institut de Bioenginyeria de Catalunya (IBEC) liderar\u00e0 el projecte OrthoBots enfocat en el tractament de malalties articulars mitjan\u00e7ant l’\u00fas de nanorobots. Aquest projecte s’inicia amb part dels resultats derivats de la tesi doctoral de Noelia Ruiz Gonz\u00e1lez, del grup de Samuel S\u00e1nchez, publicats recentment en Small<\/a><\/em>. En ell, Ruiz estudia el disseny i desenvolupament de nanorobots propulsats per enzims per al seu \u00fas en el tractament de la de malalties articulars, com l’artritis.<\/p>\n\n\n\n

L’artritis, una condici\u00f3 inflamat\u00f2ria que afecta milions de persones a tot el m\u00f3n, es caracteritza principalment per l’osteoartritis, una malaltia cr\u00f2nica degenerativa que s’agreuja amb l’edat i representa una c\u00e0rrega econ\u00f2mica significativa per als sistemes de salut.<\/p>\n\n\n\n

Una alternativa prometedora als tractaments actuals \u00e9s la ter\u00e0pia amb plasma ric en plaquetes (PRP). El PRP utilitza el potencial regeneratiu de factors de creixement, prote\u00efnes presents a la sang que s\u00f3n clau en la reparaci\u00f3 de lesions, per estimular els processos de reparaci\u00f3 tissular, especialment en c\u00e8l\u00b7lules de cart\u00edlag i ossos. No obstant aix\u00f2, \u00e9s habitual que aquestes prote\u00efnes es degradin r\u00e0pidament en entrar en contacte amb el l\u00edquid sinovial, limitant la seva efic\u00e0cia terap\u00e8utica i distribuci\u00f3.<\/p>\n\n\n\n

Per superar aquests obstacles, els cient\u00edfics estan explorant sistemes avan\u00e7ats d’alliberament de f\u00e0rmacs que utilitzen nanopart\u00edcules com transportadors. Tot i que prometedora, la difusi\u00f3 passiva de nanopart\u00edcules a trav\u00e9s de barreres biol\u00f2giques viscoses, com els fluids articulars, continua sent un obstacle significatiu.<\/p>\n\n\n\n

\n

Aquest enfocament innovador t\u00e9 un potencial transformador, possiblement revolucionant la ter\u00e0pia per a l’artritis en superar les limitacions actuals i oferir estrat\u00e8gies de tractament m\u00e9s efectives i personalitzades.<\/p>\nSamuel S\u00e1nchez<\/cite><\/blockquote>\n\n\n\n

OrthoBots es presenta com una resposta a aquest problema. El projecte busca desenvolupar nanopart\u00edcules propulsades gr\u00e0cies a enzims, coneguts com a nanorobots, amb l’objectiu de millorar el transport i la distribuci\u00f3 d’aquests factors de creixement, facilitant la regeneraci\u00f3 dirigida del cart\u00edlag.<\/p>\n\n\n\n

“Aquest enfocament innovador t\u00e9 un potencial transformador, possiblement revolucionant la ter\u00e0pia per a l’artritis en superar les limitacions actuals i oferir estrat\u00e8gies de tractament m\u00e9s efectives i personalitzades.”, destaca Samuel S\u00e1nchez, l\u00edder del projecte. A trav\u00e9s d’estudis sistem\u00e0tics in vitro<\/em> i demostracions de concepte in vivo<\/em>, OrthoBots busca aplanar el cam\u00ed per a la pr\u00f2xima generaci\u00f3 de ter\u00e0pies per a l’artritis, abordant necessitats cl\u00edniques no cobertes i millorant els resultats per als pacients.<\/p>\n\n\n\n

Per dur a terme el projecte, S\u00e1nchez ha estat guardonat amb una “ERC Proof of Concept Grant”. Es tracta d’una prestigiosa subvenci\u00f3 que concedeix el Consell Europeu de Recerca (ERC, per les seves sigles en angl\u00e8s) amb el d’objectiu explorar el potencial comercial i social de projectes de recerca que estan o han estat finan\u00e7ats pr\u00e8viament per l’ERC. Els i les sol\u00b7licitants utilitzen aquest tipus de finan\u00e7ament per verificar la viabilitat de conceptes cient\u00edfics, explorar oportunitats de negoci o preparar sol\u00b7licituds de patents. Ja \u00e9s la sisena subvenci\u00f3 que Samuel S\u00e1nchez aconsegueix per part del Consell Europeu d’Investigaci\u00f3, i la tercera en la categoria “Proof of Concept”.<\/p>\n","protected":false},"excerpt":{"rendered":"

Samuel S\u00e1nchez, professor de recerca ICREA a l’Institut de Bioenginyeria de Catalunya (IBEC) liderar\u00e0 el projecte OrthoBots enfocat en el tractament de malalties articulars mitjan\u00e7ant l’\u00fas de nanorobots. Per dur a terme el projecte, S\u00e1nchez ha estat guardonat amb una “ERC Proof of Concept Grant”, una prestigiosa subvenci\u00f3 que concedeix el Consell Europeu d’Investigaci\u00f3.<\/p>\n","protected":false},"author":37,"featured_media":119315,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[98],"tags":[2009,1140,1818],"post_formats":[],"class_list":["post-119322","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-institucionals","tag-nanobots-ca","tag-samuel-sanchez-ca","tag-smart-nano-bio-devices-ca"],"yoast_head":"\nNanorobots capa\u00e7os de travessar els fluids articulars per combatre l'artritis - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/nanorobots-capacos-de-travessar-els-fluids-articulars-per-combatre-artritis\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nanorobots capa\u00e7os de travessar els fluids articulars per combatre l'artritis - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Samuel S\u00e1nchez, professor de recerca ICREA a l'Institut de Bioenginyeria de Catalunya (IBEC) liderar\u00e0 el projecte OrthoBots enfocat en el tractament de malalties articulars mitjan\u00e7ant l'\u00fas de nanorobots. 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