{"id":12170,"date":"2015-01-29T11:44:06","date_gmt":"2015-01-29T10:44:06","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/new\/?p=12170"},"modified":"2015-02-03T16:13:59","modified_gmt":"2015-02-03T16:13:59","slug":"la-cientifica-dels-mini-ronyons-suneix-al-ibec-amb-una-subvencio-erc","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/la-cientifica-dels-mini-ronyons-suneix-al-ibec-amb-una-subvencio-erc\/","title":{"rendered":"La cient\u00edfica dels “mini-ronyons” s’uneix al IBEC amb una subvenci\u00f3 ERC"},"content":{"rendered":"

Al seu anterior lloc de treball, al Centre de Medicina Regenerativa de Barcelona (CMRB), la Dra. Montserrat era part del equip que inclo\u00efa a investigadors del Hospital Cl\u00ednic de Barcelona liderat pel Dr. Joan Carlos Izpisua del Salk Institute de Calif\u00f2rnia qui va anunciar la primera creaci\u00f3 de “mini-ronyons” en 3D a partir de c\u00e8l\u2022lules mare humanes pluripotents al 2013. Fins aleshores, els cient\u00edfics havien tingut un \u00e8xit limitat en produir c\u00e8l\u2022lules de rony\u00f3 de pacients en cultius, pel que el nou estudi va significar una revoluci\u00f3 cient\u00edfica, facilitant l’estudi de les malalties del rony\u00f3 i el descobriment de nous f\u00e0rmacs, i va anunciar un pas cap a la posada en marxa de ter\u00e0pies basades en c\u00e8l\u2022lules mare.<\/p>\n

Al IBEC la Dra. Montserrat utilitzar\u00e0 els seus cinc anys de Starting Grant del ERC – que s’atorga a joves investigadors que mostren el seu potencial de desenvolupar projectes de recerca ambiciosos, d’alt risc i d’alt guany – per construir els seus estudis sobre c\u00e8l\u2022lules mare pluripotents indu\u00efdes (iPSCs), diferenciaci\u00f3 cel\u2022lular, modelatge de malalties, edici\u00f3 de gens i regeneraci\u00f3 d\u2019\u00f2rgans. Espec\u00edficament, el seu objectiu ser\u00e0 desenvolupar m\u00e8todes per atorgar a les c\u00e8l\u2022lules mare pluripotents indu\u00efdes (iPSCs) i c\u00e8l\u2022lules mare embrion\u00e0ries humanes (hESCs) amb el potencial cl\u00ednic per regenerar el rony\u00f3. A m\u00e9s a m\u00e9s, tamb\u00e9 t\u00e9 com objectiu promoure la regeneraci\u00f3 del rony\u00f3 mitjan\u00e7ant la reactivaci\u00f3 de programes moleculars end\u00f2gens que aparentment estan presents als ronyons de mam\u00edfers poc despr\u00e9s del naixement.<\/p>\n

La Dra. Montserrat va obtenir el seu doctorat al 2006, en el que va estudiar la insulina i els factors de creixement similars a la insulina en el creixement muscular i en el seu desenvolupament. Va fer un post doctorat a l’Hospital de la Santa Creu i de Sant Pau al 2007-2008, focalitzant-se en la transici\u00f3 de l’epiteli a mes\u00e8nquima en la g\u00e8nesi del desenvolupament del carcinoma endometrial, la carrera de recerca e la Dra. Montserrat s’ha focalitzat en la reprogramaci\u00f3 som\u00e0tica, en la generaci\u00f3 de protocols per a la derivaci\u00f3 de c\u00e8l\u2022lules espec\u00edfiques especialitzades (ex. c\u00e8l\u2022lules progenitores de rony\u00f3) de c\u00e8l\u2022lules mares pluripotents, i en els mecanismes moleculars que condueixen a la regeneraci\u00f3 d\u2019\u00f2rgans en mam\u00edfers.<\/p>\n

“Estem encantats de que la N\u00faria s’uneixi a nosaltres, tant pel seu r\u00e8cord exemplar en la recerca en c\u00e8l\u2022lules mare, modelatge de malalties i en regeneraci\u00f3 d\u2019\u00f2rgans com per les seves col\u2022laboracions amb importants centres internacionals com el Salk Institute, que ens complementa i ens ajuda a desenvolupar el nostre ambient de recerca interdisciplinari,” diu el director del IBEC Josep Samitier. “Tamb\u00e9 pot ensenyar-nos molt de les seves col\u2022laboracions amb metges cl\u00ednics, com en l\u2019Hospital Cl\u00ednic. Un dels objectius estrat\u00e8gics del IBEC \u00e9s establir relacions entre investigadors i hospitals, permetent aix\u00ed que la societat es pugui beneficiar abans de la nostra recerca i de les noves tecnologies.”<\/p>\n","protected":false},"excerpt":{"rendered":"

\"nmontserrat\"Una nova investigadora principal porta al IBEC una de les subvencions m\u00e9s prestigioses, una ERC Starting Grant, per continuar la seva recerca en regeneraci\u00f3 de rony\u00f3<\/h3>\n

N\u00faria Montserrat (Barcelona, 1978) \u00e9s una de les vuit investigadores joves a Catalunya en haver rebut la prestigiosa Starting Grant del Consell Europeu de Recerca (de l’angl\u00e8s ERC) al 2014. La Dra. Montserrat, que aquest mes comen\u00e7a com a Investigadora Principal al Institut de Bioenginyeria de Catalunya (IBEC), estudiar\u00e0 les maneres de generar c\u00e8l\u00b7lules i recursos moleculars amb potencial cl\u00ednic per al tractament de malalties del rony\u00f3.<\/p>\n","protected":false},"author":4,"featured_media":12062,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[98],"tags":[],"post_formats":[],"class_list":["post-12170","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-institucionals"],"yoast_head":"\nLa cient\u00edfica dels "mini-ronyons" s'uneix al IBEC amb una subvenci\u00f3 ERC - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/la-cientifica-dels-mini-ronyons-suneix-al-ibec-amb-una-subvencio-erc\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"La cient\u00edfica dels "mini-ronyons" s'uneix al IBEC amb una subvenci\u00f3 ERC - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Una nova investigadora principal porta al IBEC una de les subvencions m\u00e9s prestigioses, una ERC Starting Grant, per continuar la seva recerca en regeneraci\u00f3 de rony\u00f3 N\u00faria Montserrat (Barcelona, 1978) \u00e9s una de les vuit investigadores joves a Catalunya en haver rebut la prestigiosa Starting Grant del Consell Europeu de Recerca (de l'angl\u00e8s ERC) al 2014. 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