{"id":126036,"date":"2025-05-27T17:13:56","date_gmt":"2025-05-27T15:13:56","guid":{"rendered":"https:\/\/ibecbarcelona.eu\/ibec-co-organised-the-leading-international-symposium-on-mutational-scanning\/"},"modified":"2025-05-28T11:47:24","modified_gmt":"2025-05-28T09:47:24","slug":"ibec-co-organised-the-leading-international-symposium-on-mutational-scanning","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/ibec-coorganitza-el-simposi-internacional-de-referencia-en-escaneig-mutacional","title":{"rendered":"IBEC coorganitza el simposi internacional de refer\u00e8ncia en escaneig mutacional"},"content":{"rendered":"\n

M\u00e9s de 300 persones van assistir la passada setmana a la vuitena edici\u00f3 del Mutational Scanning Symposium, <\/em>celebratdel21 al 23 de maig al Parc de Recerca Biom\u00e8dica de Barcelona. Es tracta d’un esdeveniment internacional de refer\u00e8ncia per debatre els \u00faltims aven\u00e7os en tecnologies d’escaneig mutacional i Assaigs multiplexats sobre l’impacte de mutacions. Enguany, el simposi va ser coorganitzat per l’Institut de Bioenginyeria de Catalunya, el Centre de Regulaci\u00f3 Gen\u00f2mica i la iniciativa internacional Atlas of Variant Effects<\/em>.<\/strong><\/strong><\/p>\n\n\n\n

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Del 21 al 23 de maig de 2025, el Parc de Recerca Biom\u00e8dica de Barcelona (PRBB) va ser l’escenari de la vuitena edici\u00f3 del Mutational Scanning Symposium (MSS)<\/em>, un esdeveniment internacional de refer\u00e8ncia que va reunir 250 assistents presencials i 60 virtuals, de 20 pa\u00efsos diferents, per debatre els \u00faltims aven\u00e7os en tecnologies d’escaneig mutacional i Assaigs multiplexats sobre l’impacte de mutacions (MAVE, per les seves sigles en angl\u00e8s). El simposi va ser coorganitzat per l’Institut de Bioenginyeria de Catalunya (IBEC), el Centre de Regulaci\u00f3 Gen\u00f2mica (CRG) i la iniciativa internacional Atlas of Variant Effects<\/em>.<\/p>\n\n\n\n

“Aquest simposi exerceix un paper clau com a pont entre la comunitat cient\u00edfica i cl\u00ednica”, afirma Bendetta Bolognesi, investigadora principal a l’IBEC i membre del comit\u00e8 organitzador del MSS 2025.<\/p>\n\n\n\n

Durant dos dies i mig, experts i expertes en gen\u00f2mica funcional, ci\u00e8ncia de prote\u00efnes, medicina de precisi\u00f3, gen\u00e8tica computacional, machine learning <\/em>(aprenentatge autom\u00e0tic) i interpretaci\u00f3 de variants van intercanviar coneixements, van presentar els seus \u00faltims treballs i van discutir sobre el futur d’aquest camp en r\u00e0pida evoluci\u00f3. El programa va incloure m\u00e9s de 30 pon\u00e8ncies cient\u00edfiques, sessions de p\u00f2sters i dos tallers interactius orientats a la interpretaci\u00f3 de variants en la pr\u00e0ctica cl\u00ednica i al disseny de prote\u00efnes.<\/p>\n\n\n\n

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Aquest simposi exerceix un paper clau com a pont entre la comunitat cient\u00edfica i cl\u00ednica.<\/p>\n\n\n\n

Benedetta Bolognesi<\/p>\n<\/blockquote>\n\n\n\n

La jornada va comptar amb ponents de renom internacional, com Dave Dams (Wellcome Sanger Institute), Julien Gagneur (Technical University of Munich), J\u00falia Domingo (ALLO-X), Polly Fordyce (Stanford University), Patrick Hsu (ARC Institute), Ylva Ivarsson (Uppsala University), Kresten Lindorff-Larsen (University of copenhagen), Matthew Coelho (Wellcome Sanger Institute), Pascal Notin (Harvard University), Ju Zheng (BGI Research), Lars Velten (CRG), Nicola Whiffin (University of Oxford), Arvind Kumar (Illumina) i Nobuhiko Tokuriki (The University of British Columbia).<\/p>\n\n\n\n

L’IBEC tamb\u00e9 va acollir el dia previ al simposi el primer taller, centrat en la selecci\u00f3 de models per a la predicci\u00f3 d’efectes de variants i el disseny de prote\u00efnes; de la m\u00e0 de Noelia Ferruz i Albert Escobedo, del CRG, i pascal Notin, de la Universitat Harvard. L’esdeveniment va finalitzar el 23 de maig amb un segon taller orientat a la transfer\u00e8ncia de dades funcionals cap a l’\u00e0mbit cl\u00ednic, posant \u00e8mfasi en com compartir conjunts de dades MAVE de forma \u00fatil per a professionals de la salut; de la m\u00e0 de Lea Starita, Abbye Mcewen i Malvika Tejura, de la Universitat de Washington i Alan Rubin, del Walter and Eliza Hall Institute.<\/p>\n\n\n\n

\n
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Ju Zheng (BGI Research)<\/figcaption><\/figure>\n\n\n\n
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J\u00falia Domingo (ALLO-X)<\/figcaption><\/figure>\n\n\n\n
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Andrew Glazer (Vanderbilt University Medical Center)<\/figcaption><\/figure>\n\n\n\n
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Entre els temes tractats van destacar la interpretaci\u00f3 funcional de variants gen\u00e8tiques, les relacions entre seq\u00fc\u00e8ncia i estructura de prote\u00efnes, la intel\u00b7lig\u00e8ncia artificial aplicada al disseny de prote\u00efnes i el modelatge biof\u00edsic. A m\u00e9s, el simposi va oferir una panor\u00e0mica de les tecnologies emergents en s\u00edntesi d’ADN, mutag\u00e8nesi de saturaci\u00f3 i un enfocament important en els \u00faltims models de machine learning<\/em> aplicats a la investigaci\u00f3 biom\u00e8dica.<\/p>\n\n\n\n

L’\u00e8xit d’assist\u00e8ncia i participaci\u00f3 va consolidar aquesta trobada com una plataforma de refer\u00e8ncia global per a investigadors i investigadores que treballen en la comprensi\u00f3 funcional del genoma hum\u00e0 i el seu impacte en la salut de cada individu. L’edici\u00f3 d’enguany ha comptat amb el suport d’entitats l\u00edders del sector com Twist Bioscience, BioMarin la Chan Zuckerberg Initiative, Illumina, Brotman Baty Institute, AstraZeneca, Constantiam Biosciences, CaixaBank i GCATbio.<\/p>\n\n\n\n

L’IBEC, com a instituci\u00f3 coorganitzadora, reafirma el seu comprom\u00eds amb la recerca interdisciplin\u00e0ria i el seu paper destacat en l’avantguarda internacional de la bioenginyeria i la gen\u00f2mica funcional.<\/p>\n\n\n\n

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Comit\u00e8 organitzador (d’esquerra a dreta): Lea Starita (Univeristy of Washington), Mafalda Dias (CRG), Lara Muffley (University of Washington), Benedetta Bolognesi (IBEC), Ben Lehner (CRG) and Jonathan Frazer (CRG).<\/figcaption><\/figure>\n<\/figure>\n","protected":false},"excerpt":{"rendered":"

M\u00e9s de 300 persones van assistir la passada setmana a la vuitena edici\u00f3 del Mutational Scanning Symposium, celebrat del 21 al 23 de maig al Parc de Recerca Biom\u00e8dica de Barcelona. Es tracta d’un esdeveniment internacional de refer\u00e8ncia per debatre els \u00faltims aven\u00e7os en tecnologies d’escaneig mutacional i Assaigs multiplexats sobre l’impacte de mutacions. Enguany, el simposi va ser coorganitzat per l’Institut de Bioenginyeria de Catalunya, el Centre de Regulaci\u00f3 Gen\u00f2mica i la iniciativa internacional Atlas of Variant Effects.<\/p>\n","protected":false},"author":37,"featured_media":125997,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[98],"tags":[1107,1731,1871],"post_formats":[],"class_list":["post-126036","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-institucionals","tag-benedetta-bolognesi-ca","tag-esdeveniment","tag-mutacions-genetiques"],"yoast_head":"\nIBEC coorganitza el simposi internacional de refer\u00e8ncia en escaneig mutacional - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/ibec-coorganitza-el-simposi-internacional-de-referencia-en-escaneig-mutacional\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"IBEC coorganitza el simposi internacional de refer\u00e8ncia en escaneig mutacional - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"M\u00e9s de 300 persones van assistir la passada setmana a la vuitena edici\u00f3 del Mutational Scanning Symposium, celebrat del 21 al 23 de maig al Parc de Recerca Biom\u00e8dica de Barcelona. Es tracta d'un esdeveniment internacional de refer\u00e8ncia per debatre els \u00faltims aven\u00e7os en tecnologies d'escaneig mutacional i Assaigs multiplexats sobre l'impacte de mutacions. 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