{"id":128947,"date":"2025-10-09T10:00:00","date_gmt":"2025-10-09T08:00:00","guid":{"rendered":"https:\/\/ibecbarcelona.eu\/?p=128947"},"modified":"2025-10-09T10:03:29","modified_gmt":"2025-10-09T08:03:29","slug":"ibec-one-of-the-centres-selected-by-the-pasqual-maragall-foundation-for-its-research-grants","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/ibec-uno-de-los-centros-seleccionados-por-la-fundacion-pasqual-maragall-para-sus-ayudas-a-la-investigacion","title":{"rendered":"L’IBEC, un dels centres seleccionats per la Fundaci\u00f3 Pasqual Maragall per als seus ajuts a la recerca"},"content":{"rendered":"\n

Amayra Hern\u00e1ndez-Vega, investigadora s\u00e8nior de l’IBEC, liderar\u00e0 un dels dos projectes seleccionats en la convocat\u00f2ria 2024 del Pasqual Maragall Researchers Programme, dedicada a finan\u00e7ar investigacions sobre l’Alzheimer i altres malalties neurodegeneratives. A m\u00e9s, l’IBEC celebra la participaci\u00f3 de Jordi Duran, investigador associat vinculat al grup de Neurobiotecnologia Molecular i Cel\u00b7lular de l’institut, com a col\u00b7laborador en el segon projecte seleccionat.<\/strong><\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n
<\/div>\n\n\n\n

El programa d’ajudes Pasqual Maragall Researchers Programme (PMRP) de la Fundaci\u00f3 Pasqual Maragall, finan\u00e7a projectes d’investigaci\u00f3 translacional o cl\u00ednica d’excel\u00b7l\u00e8ncia sobre l’Alzheimer o altres malalties neurodegeneratives relacionades amb l’edat.<\/p>\n\n\n\n

Recentment, s’han donat a con\u00e8ixer els dos projectes seleccionats en l’edici\u00f3 2024, que compta amb el suport de la Fundaci\u00f3 Adey. \u00c9s especialment destacable que tots dos inclouen la participaci\u00f3 de personal vinculat a l’Institut de Bioenginyeria de Catalunya (IBEC).<\/p>\n\n\n\n

Estudi de la Tau en la fase inicial<\/strong><\/h4>\n\n\n
\n
\"\"
Amayra Hern\u00e1ndez-Vega<\/figcaption><\/figure><\/div>\n\n\n

D’una banda, Amayra Hern\u00e1ndez-Vega<\/a>, investigadora s\u00e8nior del grup de Bi\u00f2nica Molecular de l’IBEC<\/a>, liderar\u00e0 el projecte MAPtoAD: Estudi de la Tau en la fase inicial de la seva transici\u00f3 de prote\u00efna associada a microt\u00fabuls a fibres s\u00f2lides per al tractament preco\u00e7 de la malaltia d’Alzheimer (EA).<\/p>\n\n\n\n

\n

Durant d\u00e8cades, la investigaci\u00f3 a Alzheimer s’ha centrat principalment en les fases simptom\u00e0tiques de la malaltia. El suport a aquest projecte reflecteix la visi\u00f3 pionera de la Fundaci\u00f3 en el que creiem que representa un canvi de paradigma en l’estrat\u00e8gia terap\u00e8utica<\/em><\/em>.<\/p>\n\n\n\n

Amayra Hern\u00e1ndez-Vega<\/p>\n<\/blockquote>\n\n\n\n

Se centrar\u00e0 en les fases m\u00e9s primerenques de l’Alzheimer, quan la prote\u00efna tau, clau en l’estructura neuronal, canvia el seu comportament i forma agregats patol\u00f2gics. Amb la col\u00b7laboraci\u00f3 de la Dra. Natalia Rodr\u00edguez-Muela, del Centre Alemany de Malalties Neurodegeneratives (DZNE), l’equip desenvolupar\u00e0 models reconstitu\u00efts in vitro<\/em> i models humans d’Alzheimer familiar per identificar factors desencadenants associats a l’edat i inhibidors que previnguin aquesta transici\u00f3, per tal de dissenyar estrat\u00e8gies d’intervenci\u00f3 preco\u00e7 abans de l’aparici\u00f3 de s\u00edmptomes cl\u00ednics.<\/p>\n\n\n\n

“Durant d\u00e8cades, la investigaci\u00f3 a Alzheimer s’ha centrat principalment en les fases simptom\u00e0tiques de la malaltia. El suport a aquest projecte reflecteix la visi\u00f3 pionera de la Fundaci\u00f3 en el que creiem que representa un canvi de paradigma en l’estrat\u00e8gia terap\u00e8utica”<\/em>, afegeix Amayra Hern\u00e1ndez-Vega.<\/p>\n\n\n\n

<\/div>\n\n\n\n

Reconeixement selectiu dels astr\u00f2cits<\/strong><\/h4>\n\n\n\n

D’altra banda, Jordi Duran, investigador principal i professor associat a l’Institut Qu\u00edmic de Sarri\u00e0 (IQS) \u2013 Universitat Ramon Llull (URL), ser\u00e0 col\u00b7laborador en el projecte STAR-AD: Reconeixement selectiu dels astr\u00f2cits: reprogramaci\u00f3 metab\u00f2lica en la malaltia d’Alzheimer, liderat per la professora Maite Solas, de la Universitat de Navarra (UNAV). Tot i que l’IBEC no participa directament en aquest projecte, es congratula de la implicaci\u00f3 de Duran, investigador associat al grup de Neurobiotecnologia Molecular i Cel\u00b7lular de l’IBEC<\/a>.<\/p>\n\n\n\n

El projecte se centrar\u00e0 a comprendre com els astr\u00f2cits, unes c\u00e8l\u00b7lules essencials per al correcte funcionament del cervell, modifiquen el seu metabolisme en el context de l’Alzheimer i com aquests canvis afecten processos clau com la senyalitzaci\u00f3 de la insulina o l’emmagatzematge de gluc\u00f2gen. L’equip pret\u00e9n esbrinar si intervenir en aquestes rutes metab\u00f2liques podria alentir la progressi\u00f3 de la malaltia o fins i tot revertir-la en les seves etapes inicials.<\/p>\n\n\n\n

La participaci\u00f3 de l’IBEC en aquest tipus de projectes subratlla el seu ferm comprom\u00eds amb la recerca en malalties neurodegeneratives. Des d’un enfocament interdisciplinari, l’institut treballa per comprendre els mecanismes fonamentals que subjauen a patologies com l’Alzheimer i per impulsar noves estrat\u00e8gies diagn\u00f2stiques i terap\u00e8utiques que millorin la qualitat de vida de les persones afectades i de les seves fam\u00edlies.<\/p>\n\n\n\n

M\u00e9s informaci\u00f3 sobre els projectes al web de la Fundaci\u00f3 Pasqual Maragall.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Amayra Hern\u00e1ndez-Vega, investigadora s\u00e8nior de l’IBEC, liderar\u00e0 un dels dos projectes seleccionats en la convocat\u00f2ria 2024 del Pasqual Maragall Researchers Programme, dedicada a finan\u00e7ar investigacions sobre l’Alzheimer i altres malalties neurodegeneratives. A m\u00e9s, l’IBEC celebra la participaci\u00f3 de Jordi Duran, investigador associat vinculat al grup de Neurobiotecnologia Molecular i Cel\u00b7lular de l’institut, com a col\u00b7laborador en el segon projecte seleccionat. <\/p>\n","protected":false},"author":37,"featured_media":128926,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[98],"tags":[1627,1104,1132,1581,2000],"post_formats":[],"class_list":["post-128947","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-institucionals","tag-alzheimer-ca-2","tag-giuseppe-battaglia-ca","tag-jose-antonio-del-rio-ca","tag-molecular-and-cellular-neurobiotechnology-group-ca","tag-molecular-bionics-ca"],"yoast_head":"\nL'IBEC, un dels centres seleccionats per la Fundaci\u00f3 Pasqual Maragall per als seus ajuts a la recerca - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/ibec-uno-de-los-centros-seleccionados-por-la-fundacion-pasqual-maragall-para-sus-ayudas-a-la-investigacion\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"L'IBEC, un dels centres seleccionats per la Fundaci\u00f3 Pasqual Maragall per als seus ajuts a la recerca - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Amayra Hern\u00e1ndez-Vega, investigadora s\u00e8nior de l'IBEC, liderar\u00e0 un dels dos projectes seleccionats en la convocat\u00f2ria 2024 del Pasqual Maragall Researchers Programme, dedicada a finan\u00e7ar investigacions sobre l'Alzheimer i altres malalties neurodegeneratives. 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