{"id":129977,"date":"2025-11-21T11:59:08","date_gmt":"2025-11-21T10:59:08","guid":{"rendered":"https:\/\/ibecbarcelona.eu\/?p=129977"},"modified":"2025-11-21T12:11:47","modified_gmt":"2025-11-21T11:11:47","slug":"ibec-receives-funding-from-the-la-caixa-foundations-health-research-2025-call-to-study-new-treatments-for-spinal-cord-injuries","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/ibec-rep-financament-de-la-convocatoria-health-research-2025-de-la-fundacio-la-caixa-per-estudiar-nous-tractament-per-les-lesions-medulars","title":{"rendered":"L\u2019IBEC rep finan\u00e7ament de la Convocat\u00f2ria Health Research 2025 de la Fundaci\u00f3 \u201cla Caixa\u201d per estudiar nous tractament per les lesions medul\u00b7lars"},"content":{"rendered":"\n

Zaida \u00c1lvarez Pinto, Investigadora principal de l\u2019IBEC, liderar\u00e0 un projecte de recerca biom\u00e8dica seleccionat en l\u2019edici\u00f3 2025 de la convocat\u00f2ria d\u2019Investigaci\u00f3 en Salut de la Fundaci\u00f3 \u201dla Caixa\u201d. El projecte s\u2019enfocar\u00e0 en el desenvolupament d\u2019una nova plataforma d\u2019assaig de tractaments per a les lesions medul\u00b7lars i es portar\u00e0 a terme en consorci amb l\u2019IDIBELL, la UB, la Fundaci\u00f3n Hospital Nacional de Parapl\u00e9jicos \u00a0i la Fundacion Lesionados Medulares.<\/strong><\/strong><\/p>\n\n\n\n

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D’esquerra a dreta: Eloi Monta\u00f1ez, J.Alberto Moreno, Zaida \u00c1lvarez i Elena S\u00e1nchez.<\/figcaption><\/figure>\n\n\n\n

L\u2019Institut de Bioenginyeria de Catalunya (IBEC) liderar\u00e0 un dels 34 projectes de recerca biom\u00e8dica puntera seleccionats en l\u2019edici\u00f3 2025 de la convocat\u00f2ria d\u2019Investigaci\u00f3 en Salut de la Fundaci\u00f3 \u201dla Caixa\u201d. L\u2019objectiu d\u2019aquesta convocat\u00f2ria \u00e9s identificar i impulsar iniciatives prometedores, d’excel\u00b7l\u00e8ncia cient\u00edfica i amb valor potencial i impacte social, sigui en recerca b\u00e0sica, cl\u00ednica o translacional.<\/p>\n\n\n\n

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This project is particularly significant for me and my team as it enables us to implement an idea that we have been developing for years: the necessity of creating highly representative human models to improve our understanding of spinal cord injuries and develop more effective therapies<\/em>.<\/p>\n\n\n\n

Zaida \u00c1lvarez Pinto<\/p>\n<\/blockquote>\n\n\n\n

El projecte, denominat \u201cPlataforma basada en organoides humans vascularitzats de medul\u00b7la espinal per al descobriment de f\u00e0rmacs davant lesions traum\u00e0tiques\u201d, estar\u00e0 coordinat des de l\u2019IBEC, de la m\u00e0 de Zaida \u00c1lvarez Pinto<\/strong>, investigadora principal del grup de Biomaterials per a la regeneraci\u00f3 neural de l\u2019IBEC<\/a> i comptar\u00e0 amb altres quatre organitzacions associades: l\u2019Institut d\u2019Investigaci\u00f3 Biom\u00e8dica de Bellvitge (IDIBELL<\/strong>), amb J. Alberto Ortega <\/strong>com a investigador principal; la Universitat de Barcelona (UB<\/strong>), amb Elena S\u00e1nchez<\/strong> com a investigadora principal; la Fundaci\u00f3n Hospital Nacional de Parapl\u00e9jicos para la Investigaci\u00f3n y la Integraci\u00f3n<\/strong>, amb Antonio Oliviero<\/strong> com a investigador principal; i la Fundaci\u00f3n del Lesionado Medular (FLM<\/strong>).<\/p>\n\n\n\n

Al voltant d\u2019aquest nou repte cient\u00edfic, Zaida \u00c1lvarez Pinto <\/strong>destaca que \u201caquest projecte t\u00e9 un significat especial per a mi i per al meu equip, perqu\u00e8 ens permet portar a la pr\u00e0ctica una idea que fa anys que madura: la necessitat de models humans realment representatius que ens ajudin a entendre millor les lesions de la medul\u00b7la espinal i a desenvolupar ter\u00e0pies m\u00e9s eficaces. \u00c9s una oportunitat extraordin\u00e0ria per integrar tecnologia, biologia humana i anys de coneixement en regeneraci\u00f3 neural en una \u00fanica plataforma amb potencial real d\u2019impacte cl\u00ednic<\/em>\u201d.<\/p>\n\n\n\n

La convocat\u00f2ria, que destina aquest any un total de 26 milions d\u2019euros a investigacions biom\u00e8diques d\u2019excel\u00b7l\u00e8ncia, ha concedit una subvenci\u00f3 de 999.559,03 \u20ac al consorci d\u2019investigaci\u00f3 que liderar\u00e0 \u00c1lvarez Pinto.<\/p>\n\n\n\n

Ahir, dijous 20 de novembre, va tenir lloc l\u2019acte de lliurament dels ajuts al museu de la Ci\u00e8ncia CosmoCaixa. En ella que es va comptar amb els testimonis de Zaida \u00c1lvarez i Ana Paula P\u00eago, de l’Institut de Recerca i Innovaci\u00f3 en Salut de Porto, com a l\u00edders de grup j\u00fanior i s\u00e8nior, respectivament. Ambdues van compartir els reptes i les oportunitats futures a les quals s’enfronten en la seva labor investigadora.<\/p>\n\n\n\n

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<\/div>\n\n\n\n

Nova plataforma d\u2019assaig de tractaments per a les lesions medul\u00b7lars<\/strong><\/strong><\/h4>\n\n\n\n

Les lesions de la medul\u00b7la espinal afecten centenars de milers de persones cada any i amb freq\u00fc\u00e8ncia causen par\u00e0lisi permanent o problemes f\u00edsics i emocionals tota la vida. Tot i d\u00e8cades de recerca, continua sent dif\u00edcil trobar tractaments efica\u00e7os, en gran part perqu\u00e8 els models actuals no reflecteixen amb precisi\u00f3 la biologia humana. Aquest projecte pret\u00e9n canviar la situaci\u00f3 actual mitjan\u00e7ant la creaci\u00f3 d\u2019un nou model basat en l\u2019\u00e9sser hum\u00e0 per estudiar les lesions medul\u00b7lars i assajar possibles tractaments.<\/p>\n\n\n\n

Els investigadors del projecte estan desenvolupant medul\u00b7les espinals humanes en miniatura (organoides), cultivades a partir de c\u00e8l\u00b7lules mare i combinades amb organoides vasculars per imitar millor el teixit real. Aquests organoides es col\u00b7loquen en un dispositiu impr\u00e8s en 3D i dissenyat espec\u00edficament que permet simular lesions mitjan\u00e7ant un sistema de forces <\/del>controlades per ordinador. Aquest disseny permet fer estudis precisos i repetibles sobre com es produeixen les lesions medul\u00b7lars i com respon en teixit.<\/p>\n\n\n\n

En el projecte tamb\u00e9 s\u2019assajaran dos f\u00e0rmacs comercialitzats, riluzol i minociclina, que s\u2019administraran directament al teixit lesionat mitjan\u00e7ant nanopart\u00edcules avan\u00e7ades. Aquests medicaments han demostrat ser prometedors  <\/strong>tant en estudis amb animals com en assajos cl\u00ednics amb humans, i la nova plataforma contribuir\u00e0 a determinar-ne l\u2019efic\u00e0cia en condicions similars a les humanes. L\u2019objectiu final \u00e9s crear un sistema fiable i sense necessitat d\u2019experimentaci\u00f3 animal per provar f\u00e0rmacs que sigui capa\u00e7 d\u2019accelerar el desenvolupament de tractaments per a les lesions medul\u00b7lars i altres trastorns neurol\u00f2gics.<\/p>\n","protected":false},"excerpt":{"rendered":"

Zaida \u00c1lvarez Pinto, Investigadora principal de l\u2019IBEC, liderar\u00e0 un projecte de recerca biom\u00e8dica seleccionat en l\u2019edici\u00f3 2025 de la convocat\u00f2ria d\u2019Investigaci\u00f3 en Salut de la Fundaci\u00f3 \u201dla Caixa\u201d. El projecte s\u2019enfocar\u00e0 en el desenvolupament d\u2019una nova plataforma d\u2019assaig de tractaments per a les lesions medul\u00b7lars i es portar\u00e0 a terme en consorci amb l\u2019IDIBELL, la UB, la Fundaci\u00f3n Hospital Nacional de Parapl\u00e9jicos i la Fundacion Lesionados Medulares.<\/p>\n","protected":false},"author":37,"featured_media":129968,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[98],"tags":[1965,2124,1817,1970],"post_formats":[],"class_list":["post-129977","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-institucionals","tag-biomaterials-for-neural-regeneration-group-ca","tag-caixahealth-ca","tag-premi","tag-zaida-alvarez-ca"],"yoast_head":"\nL\u2019IBEC rep finan\u00e7ament de la Convocat\u00f2ria Health Research 2025 de la Fundaci\u00f3 \u201cla Caixa\u201d per estudiar nous tractament per les lesions medul\u00b7lars - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/ibec-rep-financament-de-la-convocatoria-health-research-2025-de-la-fundacio-la-caixa-per-estudiar-nous-tractament-per-les-lesions-medulars\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"L\u2019IBEC rep finan\u00e7ament de la Convocat\u00f2ria Health Research 2025 de la Fundaci\u00f3 \u201cla Caixa\u201d per estudiar nous tractament per les lesions medul\u00b7lars - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Zaida \u00c1lvarez Pinto, Investigadora principal de l\u2019IBEC, liderar\u00e0 un projecte de recerca biom\u00e8dica seleccionat en l\u2019edici\u00f3 2025 de la convocat\u00f2ria d\u2019Investigaci\u00f3 en Salut de la Fundaci\u00f3 \u201dla Caixa\u201d. 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