{"id":134402,"date":"2026-06-26T10:59:32","date_gmt":"2026-06-26T08:59:32","guid":{"rendered":"https:\/\/ibecbarcelona.eu\/ibec-participates-in-three-projects-that-have-contributed-to-covid-19-advances-driven-by-la-marato-2020\/"},"modified":"2026-06-26T11:24:51","modified_gmt":"2026-06-26T09:24:51","slug":"ibec-participa-en-tres-projectes-que-han-contribuit-als-avencos-en-covid-19-impulsats-per-la-marato-2020","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/ibec-participa-en-tres-projectes-que-han-contribuit-als-avencos-en-covid-19-impulsats-per-la-marato-2020\/","title":{"rendered":"L\u2019IBEC participa en tres projectes que han contribu\u00eft als aven\u00e7os en covid-19 impulsats per La Marat\u00f3 2020"},"content":{"rendered":"\n

El passat 18 de juny es van fer p\u00fablics els resultats dels 36 projectes de recerca finan\u00e7ats per La Marat\u00f3 de 3Cat en la convocat\u00f2ria extraordin\u00e0ria del 2020, dedicada a la covid-19. L\u2019Institut de Bioenginyeria de Catalunya (IBEC) va participar en tres d\u2019aquests projectes, centrats a aprofundir en el coneixement de la malaltia i a millorar-ne el diagn\u00f2stic i el seguiment cl\u00ednic.<\/strong><\/strong><\/p>\n\n\n\n

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L\u2019Institut de Bioenginyeria de Catalunya (IBEC) va participar en tres dels 36 projectes de recerca finan\u00e7ats per La Marat\u00f3 de 3Cat en la convocat\u00f2ria extraordin\u00e0ria del 2020, dedicada a la covid-19. Sis anys despr\u00e9s, la Fundaci\u00f3 La Marat\u00f3 va fer p\u00fablics els resultats d\u2019aquesta inversi\u00f3 hist\u00f2rica, que va mobilitzar prop de 14 milions d\u2019euros i va implicar 98 equips de recerca.<\/p>\n\n\n\n

Els projectes amb participaci\u00f3 de l\u2019IBEC van contribuir a millorar el coneixement dels mecanismes biol\u00f2gics del SARS-CoV-2 i a desenvolupar noves eines per al diagn\u00f2stic i el seguiment de la malaltia, especialment en pacients amb afectaci\u00f3 respirat\u00f2ria greu.<\/p>\n\n\n\n

Nous models per entendre la infecci\u00f3 i identificar dianes terap\u00e8utiques<\/strong><\/strong><\/h4>\n\n\n\n
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Un dels projectes, SYSTORG<\/strong>, ha estat coordinat per la Dra. N\u00faria Montserrat<\/strong> (professora de investigaci\u00f3 ICREA a l\u2019IBEC i l\u00edder del grup de Puripot\u00e8ncia per a la regeneraci\u00f3 d\u2019\u00f2rgans<\/a> en el moment de l\u2019estudi) i va reunir un consorci internacional amb els equips del Dr. Josef Penninger<\/strong> (Medical Univeristy of Vienna) i el Dr. Ali Mirazimi<\/strong> (Karolinska Institute Stockholm LABMED) per estudiar com diferents condicions sist\u00e8miques afectaven la infecci\u00f3 per SARS-CoV-2. Utilitzant organoides derivats de c\u00e8l\u00b7lules mare pluripotents humanes i eines d\u2019enginyeria gen\u00e8tica, l\u2019equip va desenvolupar models avan\u00e7ats que replicaven millor la complexitat del teixit hum\u00e0.<\/p>\n\n\n\n

Els resultats van demostrar que processos metab\u00f2lics associats a la diabetis augmentaven la susceptibilitat a la infecci\u00f3 i van permetre identificar receptors cel\u00b7lulars i biomarcadors clau en les primeres fases de la malaltia. A m\u00e9s, el projecte va contribuir a validar un compost terap\u00e8utic actualment en assaig cl\u00ednic i va obrir noves vies per al desenvolupament de ter\u00e0pies personalitzades.<\/p>\n\n\n\n

Monitoratge no invasiu del patr\u00f3 respiratori<\/strong><\/strong><\/h4>\n\n\n\n
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El segon projecte, coordinat per la Dra. Arantxa Mas<\/strong> (Institut de Recerca Hospital de la Santa Creu i Sant Pau) i de la Dra. Beatriz Giraldo<\/strong> (investigadora s\u00e8nior del grup de\u00a0Processament i interpretaci\u00f3 de senyals biom\u00e8dics (BIOSPIN)<\/a>\u00a0de l\u2019IBEC), es va centrar en la monitoritzaci\u00f3 cont\u00ednua i no invasiva del patr\u00f3 respiratori en pacients amb pneum\u00f2nia greu per covid-19.<\/p>\n\n\n\n

L\u2019estudi va demostrar que la temperatura de l\u2019aire mesurada dins d\u2019una m\u00e0scara permetia inferir par\u00e0metres clau com la freq\u00fc\u00e8ncia respirat\u00f2ria i el volum corrent. Els investigadors tamb\u00e9 van observar que una disminuci\u00f3 en la variabilitat del patr\u00f3 respiratori podia actuar com a predictor preco\u00e7 de mala evoluci\u00f3 cl\u00ednica.<\/p>\n\n\n\n

Aquests resultats van representar un pas endavant cap a sistemes de monitoritzaci\u00f3 m\u00e9s accessibles i continus, amb potencial per millorar el seguiment dels pacients i optimitzar les decisions cl\u00edniques, tot i que encara es requereixen estudis addicionals per a la seva implementaci\u00f3 en la pr\u00e0ctica habitual.<\/a><\/p>\n\n\n\n

Predicci\u00f3 del pron\u00f2stic en pacients cr\u00edtics<\/strong><\/strong><\/h4>\n\n\n\n
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Finalment, el projecte CoRespiRomics<\/strong>, liderat pel Dr. Joan Ramon Masclans<\/strong> (Institut Hospital del Mar d’Investigacions M\u00e8diques) i el Dr. Santiago Marco <\/strong>(investigador principal del grup de Processament de Senyals i Informaci\u00f3 per a Sistemes Sensors<\/a> de l\u2019IBEC), va abordar la necessitat de predir l\u2019evoluci\u00f3 dels pacients greus amb covid-19 sotmesos a ter\u00e0pies respirat\u00f2ries no invasives.<\/p>\n\n\n\n

Els investigadors van identificar un conjunt de nou biomarcadors metabol\u00f2mics, combinats amb dos criteris cl\u00ednics, que permetien predir amb m\u00e9s precisi\u00f3 la resposta al tractament que els indicadors utilitzats fins al moment. Aquesta aproximaci\u00f3 podia ajudar a identificar preco\u00e7ment els pacients amb risc de mala evoluci\u00f3 i a prendre decisions cl\u00edniques m\u00e9s r\u00e0pides, com la necessitat d\u2019intubaci\u00f3, millorant aix\u00ed el pron\u00f2stic.<\/p>\n\n\n\n

Recerca impulsada per la solidaritat<\/strong><\/strong><\/h4>\n\n\n\n

La Marat\u00f3 2020 va aconseguir una recaptaci\u00f3 excepcional de 13,8 milions d\u2019euros en un context marcat per la pand\u00e8mia, fet que va permetre impulsar la primera gran inversi\u00f3 en una malaltia infecciosa emergent. Els 36 projectes finan\u00e7ats van implicar m\u00e9s de 850 investigadors i investigadores amb l\u2019objectiu com\u00fa d\u2019avan\u00e7ar en el diagn\u00f2stic, el tractament i la prevenci\u00f3 de la covid-19.<\/p>\n\n\n\n

Els resultats presentats evidencien com la recerca impulsada per la solidaritat ciutadana va generar aven\u00e7os significatius en un temps r\u00e8cord i va contribuir a millorar la resposta davant d\u2019una crisi sanit\u00e0ria global sense precedents.<\/p>\n\n\n\n

Amb la seva participaci\u00f3 en tres d\u2019aquests projectes, l\u2019IBEC consolida el seu paper en la recerca interdisciplin\u00e0ria en bioenginyeria aplicada a la salut i contribueix al progr\u00e9s cient\u00edfic en la lluita contra la covid-19.<\/p>\n\n\n\n

Per saber-ne m\u00e9s del projectes, consultar la web de La Marat\u00f3<\/a>.<\/pre>\n\n\n\n
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El passat 18 de juny es van fer p\u00fablics els resultats dels 36 projectes de recerca finan\u00e7ats per La Marat\u00f3 de 3Cat en la convocat\u00f2ria extraordin\u00e0ria del 2020, dedicada a la covid-19. L\u2019Institut de Bioenginyeria de Catalunya (IBEC) va participar en tres d\u2019aquests projectes, centrats a aprofundir en el coneixement de la malaltia i a millorar-ne el diagn\u00f2stic i el seguiment cl\u00ednic.<\/p>\n","protected":false},"author":37,"featured_media":134386,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[98],"tags":[2066,923,1123,1780,1817,1116,1118,1778],"post_formats":[],"class_list":["post-134402","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-institucionals","tag-biomedical-signal-processing-and-interpretation-ca","tag-covid-ca","tag-nuria-montserrat-ca-2","tag-pluripotency-for-organ-regeneration-ca","tag-premi","tag-raimon-jane-ca","tag-santiago-marco-ca","tag-signal-and-information-processing-for-sensing-systems-ca"],"yoast_head":"\nL\u2019IBEC participa en tres projectes que han contribu\u00eft als aven\u00e7os en covid-19 impulsats per La Marat\u00f3 2020 - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/ibec-participa-en-tres-projectes-que-han-contribuit-als-avencos-en-covid-19-impulsats-per-la-marato-2020\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"L\u2019IBEC participa en tres projectes que han contribu\u00eft als aven\u00e7os en covid-19 impulsats per La Marat\u00f3 2020 - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"El passat 18 de juny es van fer p\u00fablics els resultats dels 36 projectes de recerca finan\u00e7ats per La Marat\u00f3 de 3Cat en la convocat\u00f2ria extraordin\u00e0ria del 2020, dedicada a la covid-19. 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