{"id":137459,"date":"2026-11-09T10:05:23","date_gmt":"2026-11-09T09:05:23","guid":{"rendered":"https:\/\/ibecbarcelona.eu\/ibec-and-iqs-host-the-3rd-barcelona-blood-brain-barrier-conference\/"},"modified":"2026-11-09T10:26:32","modified_gmt":"2026-11-09T09:26:32","slug":"ibec-i-iqs-organitzen-la-tercera-edicio-de-la-barcelona-blood-brain-barrier-conference","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/ibec-i-iqs-organitzen-la-tercera-edicio-de-la-barcelona-blood-brain-barrier-conference\/","title":{"rendered":"L&#8217;IBEC i l&#8217;IQS organitzen la tercera edici\u00f3 de la Barcelona Blood-Brain Barrier Conference"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong><strong>La tercera edici\u00f3 de la Barcelona Blood-Brain Barrier (B4) Conference, organitzada conjuntament per l&#8217;Institut de Bioenginyeria de Catalunya (IBEC) i l&#8217;Institut Qu\u00edmic de Sarri\u00e0 (IQS), es va celebrar del 3 al 5 de novembre de 2026 al Parc de Recerca Biom\u00e8dica de Barcelona (PRBB). Durant tres dies, 200 investigadors i investigadores de tot el m\u00f3n van compartir els seus darrers treballs sobre la barrera hematoencef\u00e0lica (BBB, per les seves sigles en angl\u00e8s): des de com es forma i funciona fins al seu paper en la malaltia i les noves estrat\u00e8gies per fer arribar tractaments al cervell.<\/strong><\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1939\" height=\"1091\" src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/11\/Group-picture-Editada.jpg\" alt=\"\" class=\"wp-image-137453\"\/><\/figure>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">La BBB separa la circulaci\u00f3 sangu\u00ednia del teixit cerebral. Lluny de ser un mur est\u00e0tic, \u00e9s una interf\u00edcie molt din\u00e0mica que protegeix el cervell alhora que respon a les seves necessitats canviants. Tamb\u00e9 \u00e9s un dels principals obstacles perqu\u00e8 els f\u00e0rmacs arribin al cervell, cosa que la converteix en un tema central tant per comprendre les malalties neurol\u00f2giques com per desenvolupar nous tractaments. La confer\u00e8ncia va estar presidida per <strong>Daniel Gonzalez-Carter<\/strong>, investigador s\u00e8nior Ram\u00f3n y Cajal a l&#8217;IBEC; <strong>Benjam\u00ed Oller Salvia<\/strong>, cap de grup a l&#8217;IQS \u2013 Universitat Ramon Llull, i <strong>Giuseppe Battaglia<\/strong>, professor d&#8217;investigaci\u00f3 ICREA i l\u00edder del grup de <a href=\"https:\/\/ibecbarcelona.eu\/ca\/research-groups\/molecular-bionics\/\" target=\"_blank\" rel=\"noopener\">Bi\u00f2nica Molecular<\/a> de l&#8217;IBEC.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">El programa va combinar confer\u00e8ncies plen\u00e0ries, xerrades convidades, sessions orals paral\u00b7leles i tres sessions de p\u00f2sters, amb prop de 70 presentacions orals i m\u00e9s de 60 p\u00f2sters, i va reunir disciplines com la neuroci\u00e8ncia, la biologia vascular, l&#8217;enginyeria de prote\u00efnes, la bioenginyeria i la nanomedicina.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong><strong>Confer\u00e8ncies plen\u00e0ries<\/strong><\/strong><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Benoit Vanhollebeke<\/strong>, de la Universit\u00e9 libre de Bruxelles (ULB, B\u00e8lgica), va inaugurar la confer\u00e8ncia amb una pon\u00e8ncia sobre la regulaci\u00f3 a escala de c\u00e8l\u00b7lula individual de l&#8217;angiog\u00e8nesi cerebral i la formaci\u00f3 de la BBB, des dels mecanismes moleculars fins a les estrat\u00e8gies per reparar la barrera. El seu laboratori, finan\u00e7at pel Consell Europeu de Recerca (ERC), estudia les vies de senyalitzaci\u00f3 que controlen el creixement dels vasos sanguinis cerebrals i la integritat de la barrera.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">El segon dia, <strong>Feng Shao<\/strong>, investigador i director adjunt del National Institute of Biological Sciences (NIBS) de Pequ\u00edn (Xina), va presentar la seva recerca sobre com l&#8217;activaci\u00f3 de la prote\u00efna gasdermina D (GSDMD) a les c\u00e8l\u00b7lules endotelials cerebrals interv\u00e9 en la ruptura de la BBB durant la inflamaci\u00f3.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Viviana Gradinaru<\/strong>, catedr\u00e0tica de Neuroci\u00e8ncia i Enginyeria Biol\u00f2gica del California Institute of Technology (Caltech, Estats Units), va obrir l&#8217;\u00faltima jornada amb una xerrada sobre la BBB com a \u00abamiga i enemiga\u00bb: una defensa per al cervell i, alhora, una barrera per als tractaments. El seu laboratori estudia les interaccions entre el cervell i la resta del cos en la neurodegeneraci\u00f3 i desenvolupa tecnologies per fer arribar gens al cervell a trav\u00e9s del torrent sanguini, en lloc de fer-ho mitjan\u00e7ant cirurgia.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong><strong>Xerrades convidades i programa cient\u00edfic<\/strong><\/strong><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">El programa tamb\u00e9 va incloure nou xerrades convidades, a c\u00e0rrec de <strong>Miguel Castanho<\/strong> (Universitat de Lisboa, Portugal), <strong>Kylie Chew<\/strong> (Denali Therapeutics, Estats Units), <strong>Blanca D\u00edaz-Castro<\/strong> (UK Dementia Research Institute, Universitat d&#8217;Edimburg, Regne Unit), <strong>Kavi Devraj<\/strong> (BITS Pilani, campus d&#8217;Hyderabad, \u00cdndia), <strong>Simon McArthur<\/strong> (Queen Mary University of London, Regne Unit), <strong>Joseph Nicolazzo<\/strong> (Monash University, Austr\u00e0lia), <strong>Dominik Paquet<\/strong> (LMU de Munic, Alemanya), <strong>Carmen Ruiz de Almod\u00f3var<\/strong> (Universitat de Bonn, Alemanya) i <strong>Avi Schroeder<\/strong> (Technion \u2013 Israel Institute of Technology, Israel). Les pon\u00e8ncies van abastar des de les infeccions v\u00edriques del cervell i l&#8217;eix intest\u00ed-cervell fins a les interaccions entre astr\u00f2cits i vasculatura en la dem\u00e8ncia, els models 3D de teixit cerebral hum\u00e0 derivats de c\u00e8l\u00b7lules mare i l&#8217;\u00fas de la intel\u00b7lig\u00e8ncia artificial en el disseny de nanopart\u00edcules.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A les sessions paral\u00b7leles, les persones participants van debatre sobre el paper de la BBB en la malaltia d&#8217;Alzheimer i altres formes de dem\u00e8ncia, l&#8217;ictus, l&#8217;epil\u00e8psia, els tumors cerebrals i l&#8217;envelliment, com tamb\u00e9 sobre enfocaments d&#8217;enginyeria per travessar la barrera, com ara els nanotransportadors, les \u00abllan\u00e7adores cerebrals\u00bb basades en anticossos (<em>brain shuttles<\/em>), els dispositius de barrera hematoencef\u00e0lica en un xip (<em>BBB-on-a-chip<\/em>) i els models <em>in vitro<\/em> constru\u00efts a partir de c\u00e8l\u00b7lules mare pluripotents indu\u00efdes humanes (iPSC, per les seves sigles en angl\u00e8s).<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong><strong>Premis al talent investigador emergent<\/strong><\/strong><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Com en l&#8217;edici\u00f3 anterior, la confer\u00e8ncia va recon\u00e8ixer la feina d&#8217;investigadors i investigadores en les primeres etapes de la seva carrera amb premis als millors p\u00f2sters i presentacions orals, amb el suport de la International Brain Barriers Society (IBBS). En la categoria de p\u00f2ster, el primer premi va ser per a <strong>Clo\u00e9 Mo\u00eblo<\/strong>, del Karolinska Institutet (Su\u00e8cia), i el segon per a <strong>Georgios Tsafaras<\/strong>, del VIB-KU Leuven Center for Brain &amp; Disease Research (B\u00e8lgica). En la categoria de presentaci\u00f3 oral, el primer premi va ser per a <strong>Chiara Zamboni<\/strong>, de l&#8217;Institute for Translational Research (IRT, Su\u00efssa), i el segon per a <strong>Burcu Yaldiz<\/strong>, de l&#8217;IQS \u2013 Universitat Ramon Llull (Barcelona).<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/11\/Presentation-winners.jpg-Editada-scaled.jpg\" alt=\"\" class=\"wp-image-137456\"\/><\/figure>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Amb aquesta tercera edici\u00f3, la B4 Conference es consolida com a punt de trobada internacional de la comunitat cient\u00edfica dedicada a la BBB i refor\u00e7a els vincles entre disciplines i entre la recerca b\u00e0sica i la translacional.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/03\/S-WEB-Goal-03-1024x1024.png\" alt=\"\" class=\"wp-image-133028\" style=\"width:150px;height:auto\" srcset=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/03\/S-WEB-Goal-03-1024x1024.png 1024w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/03\/S-WEB-Goal-03-300x300.png 300w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/03\/S-WEB-Goal-03-150x150.png 150w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/03\/S-WEB-Goal-03-768x768.png 768w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/03\/S-WEB-Goal-03-1200x1200.png 1200w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/03\/S-WEB-Goal-03-600x600.png 600w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/03\/S-WEB-Goal-03.png 1500w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/05\/S-WEB-Goal-17-1024x1024.png\" alt=\"\" class=\"wp-image-133546\" style=\"width:150px;height:auto\" srcset=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/05\/S-WEB-Goal-17-1024x1024.png 1024w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/05\/S-WEB-Goal-17-300x300.png 300w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/05\/S-WEB-Goal-17-150x150.png 150w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/05\/S-WEB-Goal-17-768x768.png 768w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/05\/S-WEB-Goal-17-1200x1200.png 1200w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/05\/S-WEB-Goal-17-600x600.png 600w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2026\/05\/S-WEB-Goal-17.png 1500w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>La tercera edici\u00f3 de la Barcelona Blood-Brain Barrier (B4) Conference, organitzada conjuntament per l&#8217;Institut de Bioenginyeria de Catalunya (IBEC) i l&#8217;Institut Qu\u00edmic de Sarri\u00e0 (IQS), es va celebrar del 3 al 5 de novembre de 2026 al Parc de Recerca Biom\u00e8dica de Barcelona (PRBB). Durant tres dies, 200 investigadors i investigadores de tot el m\u00f3n van compartir els seus darrers treballs sobre la barrera hematoencef\u00e0lica (BBB, per les seves sigles en angl\u00e8s): des de com es forma i funciona fins al seu paper en la malaltia i les noves estrat\u00e8gies per fer arribar tractaments al cervell.<\/p>\n","protected":false},"author":37,"featured_media":137453,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[98],"tags":[1731,1104,2000],"post_formats":[],"class_list":["post-137459","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-institucionals","tag-esdeveniment","tag-giuseppe-battaglia-ca","tag-molecular-bionics-ca"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>L&#039;IBEC i l&#039;IQS organitzen la tercera edici\u00f3 de la Barcelona Blood-Brain Barrier Conference - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/ibec-i-iqs-organitzen-la-tercera-edicio-de-la-barcelona-blood-brain-barrier-conference\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"L&#039;IBEC i l&#039;IQS organitzen la tercera edici\u00f3 de la Barcelona Blood-Brain Barrier Conference - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"La tercera edici\u00f3 de la Barcelona Blood-Brain Barrier (B4) Conference, organitzada conjuntament per l&#039;Institut de Bioenginyeria de Catalunya (IBEC) i l&#039;Institut Qu\u00edmic de Sarri\u00e0 (IQS), es va celebrar del 3 al 5 de novembre de 2026 al Parc de Recerca Biom\u00e8dica de Barcelona (PRBB). 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