{"id":23426,"date":"2016-06-10T10:08:05","date_gmt":"2016-06-10T10:08:05","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=23426"},"modified":"2016-06-13T08:23:32","modified_gmt":"2016-06-13T08:23:32","slug":"lus-de-la-impressio-3d-per-produir-eines-crucials-per-a-la-recerca","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/lus-de-la-impressio-3d-per-produir-eines-crucials-per-a-la-recerca\/","title":{"rendered":"L’\u00fas de la impressi\u00f3 3D per produir eines crucials per a la recerca"},"content":{"rendered":"

Aquestes s\u00f3n eines crucials en moltes \u00e0rees de la recerca biom\u00e8dica, com l’an\u00e0lisi d’ADN, la tecnologia del laboratori-en-un-xip, un sistema que permet als bi\u00f2legs cel\u00b7lulars controlar l’entorn cel\u00b7lular complet.<\/p>\n

L’estudi, Publicat en Lab<\/span> on a Xip, descriu una millora important en la manera en la qual es poden produir sistemes microflu\u00eddics<\/span>. Fins ara, la majoria s’han modelat en poli<\/span> (dimetilsilox\u00e0<\/span>), o PDMS<\/span>, per un m\u00e8tode conegut com a litografia tova. Encara que el PDMS<\/span> ofereix les propietats requerides per als sistemes microflu\u00eddics<\/span> – \u00e9s biocompatible, elastom\u00e8ric, transparent, permeable al gas, de baix cost, i lliure de drets d’autor – la t\u00e8cnica \u00e9s lenta i complexa.<\/p>\n

Utilitzant un tipus diferent de resina, poli<\/span> (etilenglicol) diacrilat<\/span> o PEG<\/span>–DA<\/span>, i un m\u00e8tode d’impressi\u00f3 en 3D conegut com a estereolitografia<\/span>, els investigadors han estat capa\u00e7os de construir un dispositiu transparent amb una impresa en 3D- perqu\u00e8 els sistemes microflu\u00eddics<\/span> necessiten tenir una excel\u00b7lent visibilitat – en el qual les c\u00e8l\u00b7lules poden conrear-se durant diversos dies.<\/p>\n

“Amb aquesta nova resina biocompatible i el nou proc\u00e9s d’impressi\u00f3 3D, evitem els inconvenients dels dispositius PDMS<\/span>, que a m\u00e9s de ser tediosos de fer, eren propensos a fallades de muntatge i, conseq\u00fcentment, dificultaven la difusi\u00f3 de la recerca i la pr\u00e0ctica cl\u00ednica”, explica el director de l’IBEC<\/span> Josep Samitier, l’estudiant del qual de doctorat, Luis<\/span> G. Rigat<\/span>, va fer una estada de recerca a la Universitat de Washington per aprendre dels investigadors que ja treballen amb la impressi\u00f3 en 3D i portar el seu nou coneixement a l’IBEC<\/span>. “Mitjan\u00e7ant l’\u00fas de la estereolitografia<\/span>, que \u00e9s automatitzat, m\u00e9s barat, lliure de muntatge i m\u00e9s r\u00e0pid, tamb\u00e9 hem millorat el procediment de fabricaci\u00f3, que solia estar limitada als dissenys simples, en capes. Ara podem fer estructures 3D molt m\u00e9s complexes.” El nou proc\u00e9s tamb\u00e9 es pot aplicar en altres \u00e0rees, com en la producci\u00f3 de dispositius biom\u00e8dics no microflu\u00eddics<\/span>.<\/p>\n

Aquest descobriment ja comen\u00e7a a transformar la forma de treball dels investigadors, oferint millors m\u00e8todes com aquest, les impressores 3D – i especialment les bioimpressores<\/span> 3D, com de la qual disposa l’IBEC<\/span> – ofereixen una manera r\u00e0pida i d’alt rendiment per produir constructes tals com a bastides o implants que mantenen la funci\u00f3 i la viabilitat cel\u00b7lular, per la qual cosa representen un gran avan\u00e7 cap a la possibilitat de produir teixits d’escala humana amb integritat estructural.<\/p>\n

—<\/p>\n

Article de refer\u00e8ncia: <\/strong>Arturo Urrios, Cesar Parra-Cabrera, Nirveek Bhattacharjee, Alan M Gonzalez-Suarez, Luis Guillermo Rigat Brugarolas, Umashree Nallapati, Josep Samitier, Cole DeForest, Francesc Posas, Jose L Garcia-Cordero and Albert Folch (2016). 3D-Printing of Transparent Bio-Microfluidic Devices in PEG-DA.<\/a> Lab Chip<\/em>, 16, 2287-2294<\/p>\n","protected":false},"excerpt":{"rendered":"

\"samluis\"<\/a>Amb la impressi\u00f3 3D es revolucionar\u00e0 la recerca, els investigadors de l’IBEC han estat explorant les possibilitats que ofereix la nova tecnologia per millorar els seus processos i m\u00e8todes.<\/h3>\n

Recentment l’IBEC s’ha convertit en la llar de la primera bioimpressora 3D de Catalunya, que promet obrir noves vies en el camp de regeneraci\u00f3 de teixits i \u00f2rgans. No obstant aix\u00f2, en una col\u00b7laboraci\u00f3 amb la UPF, el CINVESTAV-Monterrey, a M\u00e8xic, i la Universitat de Washington, els cient\u00edfics amb seu a Barcelona, van desenvolupar una nova forma de produir dispositius microflu\u00eddics – sistemes en qu\u00e8 obtenen baixos volums de fluids.<\/p>\n","protected":false},"author":4,"featured_media":23411,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96],"tags":[],"post_formats":[],"class_list":["post-23426","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-de-recerca"],"yoast_head":"\nL'\u00fas de la impressi\u00f3 3D per produir eines crucials per a la recerca - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/lus-de-la-impressio-3d-per-produir-eines-crucials-per-a-la-recerca\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"L'\u00fas de la impressi\u00f3 3D per produir eines crucials per a la recerca - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Amb la impressi\u00f3 3D es revolucionar\u00e0 la recerca, els investigadors de l'IBEC han estat explorant les possibilitats que ofereix la nova tecnologia per millorar els seus processos i m\u00e8todes. 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