{"id":23528,"date":"2016-06-23T09:46:57","date_gmt":"2016-06-23T07:46:57","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=23528"},"modified":"2016-07-07T12:42:36","modified_gmt":"2016-07-07T10:42:36","slug":"micobacterias-en-aceite-de-oliva-para-el-tratamiento-del-cancer-2","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/micobacterias-en-aceite-de-oliva-para-el-tratamiento-del-cancer-2\/","title":{"rendered":"Micobacteris en oli d’oliva per al tractament del c\u00e0ncer"},"content":{"rendered":"

Aquesta formaci\u00f3 de grumolls pot interferir amb la interacci\u00f3 de les c\u00e8l\u00b7lules micobacterianes i les c\u00e8l\u00b7lules de l’organisme i disminuir els efectes antitumorals.<\/p>\n

Despr\u00e9s d’anunciar el descobriment, l’any passat, que les c\u00e8l\u00b7lules de Mycobacterium<\/span> brumae<\/span> ofereixen una alternativa que millora els tractaments actuals per al c\u00e0ncer de bufeta, com el BCG<\/span> que pot causar infeccions, els col\u00b7laboradors \u2013 liderats per Esther<\/span> Juli\u00e1n<\/span> en la UAB \u2013 han buscat la manera per millorar l’activitat inmunoterapeutica<\/span> de M. Brumae<\/span>. Per a aix\u00f2, han dissenyat diferents emulsions que poden augmentar l’homogene\u00eftat i l’estabilitat, i per tant l’efic\u00e0cia, de les solucions de Mycobacterium<\/span> quan s’introdueix en el cos.<\/p>\n

“De les emulsions que vam provar, la que est\u00e0 basada en l’oli d’oliva indueix una resposta immune important tan in vitro com in<\/span> vivo<\/span>. A m\u00e9s aquesta emulsi\u00f3 es caracteritza per conservar la viabilitat dels micobacteris i proporcionar taxes de antiaglutinaci\u00f3<\/span> m\u00e9s elevades, aquestes caracter\u00edstiques indiquen que les condicions s\u00f3n favorables per aconseguir l’epiteli de la bufeta”, diu Eduard Torrents, responsable de grup del IBEC<\/span>, que va contribuir a l’estudi. “Els resultats posen de manifest el potencial d’aquesta emulsi\u00f3 en base d’oli d’oliva com un vehicle de subministrament prometedor per al tractament amb micobacteris del c\u00e0ncer de bufeta.”<\/p>\n

El treball ha estat dut a terme per investigadors del Departament de Gen\u00e8tica i Microbiologia de la Facultat de Ci\u00e8ncies Biol\u00f2giques, del Departament de Medicina i Cirurgia Animal de la Facultat de Veterin\u00e0ria, i del Servei de Microbiologia de la UAB, i el grup d’Eduard Torrents, Infeccions Bacterianes: Ter\u00e0pies antimicrobianes del IBEC<\/span>.<\/p>\n

—<\/p>\n

Article de refer\u00e8ncia:<\/em><\/strong> Estela Noguera-Ortega, N\u00faria Blanco-Cabra, Rosa Maria Rabanal, Alejandro S\u00e1nchez-Chardi, M\u00f3nica Rold\u00e1n, Sandra Guallar-Garrido, Eduard Torrents, Marina Luquin & Esther Juli\u00e1n (2016). \u201cMycobacteria emulsified in olive oil-in-water trigger a robust immune response in bladder cancer treatment.\u201d Scientific Reports<\/em>, 6:27232. http:\/\/www.nature.com\/articles\/srep27232<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

\"micobacteris\"<\/a>Investigadors de la UAB i de l’Institut de Bioenginyeria de Catalunya (IBEC) han descobert una manera efectiva d’administrar el micobacteri M. brumae necess\u00e0ri pel tractament de c\u00e0ncer de bufeta en humans<\/h3>\n

Els investigadors han trobat una forma de reduir la formaci\u00f3 dels grumolls naturals que es produeixen quan s’introdueix els micobacteris, que posseeixen un alt contingut de l\u00edpids en les seves parets, en les solucions aquoses que habitualment s’utilitzen per a la instil\u00b7laci\u00f3 intravesical \u2013 l’aplicaci\u00f3 directa de medicament mitjan\u00e7ant degoteig -en pacients amb c\u00e0ncer de bufeta. <\/p>\n","protected":false},"author":4,"featured_media":23517,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96],"tags":[],"post_formats":[],"class_list":["post-23528","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-de-recerca"],"yoast_head":"\nMicobacteris en oli d'oliva per al tractament del c\u00e0ncer - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, 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