{"id":27052,"date":"2017-01-11T11:26:37","date_gmt":"2017-01-11T10:26:37","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=27052"},"modified":"2017-01-11T13:02:14","modified_gmt":"2017-01-11T12:02:14","slug":"libec-coordinara-un-projecte-de-set-milions-deuros-per-desenvolupar-terapies-contra-el-cancer-i-altres-malalties","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/libec-coordinara-un-projecte-de-set-milions-deuros-per-desenvolupar-terapies-contra-el-cancer-i-altres-malalties\/","title":{"rendered":"L&#8217;IBEC coordinar\u00e0 un projecte de set milions d&#8217;euros per desenvolupar ter\u00e0pies contra el c\u00e0ncer i altres malalties"},"content":{"rendered":"<p>MECHANOCONTROL\u00a0forma part del programa\u00a0<a href=\"http:\/\/www.h2020.md\/en\/12-new-fet-proactive-projects-defy-bounds-innovation\" target=\"_blank\">FET Proactive<\/a>\u00a0de\u00a0Horizon\u00a02020, que promociona el desenvolupament de noves comunitats d&#8217;investigadors multidisciplinaris. En particular, el projecte busca desxifrar i controlar com les c\u00e8l\u00b7lules transmeten i detecten les forces mec\u00e0niques.<\/p>\n<p>\u201cLa majoria dels tumors s\u00f2lids sofreixen alteracions en les seves propietats mec\u00e0niques, per exemple augmentant la seva rigidesa respecte a la del teixit sa. L&#8217;enduriment promou la progressi\u00f3 del tumor\u201d, explica Pere Roca-Cusachs. \u201cAix\u00f2 no solament fa refer\u00e8ncia al c\u00e0ncer, altres malalties com la\u00a0fibrosi\u00a0tamb\u00e9 depenen de l&#8217;augment de rigidesa del teixit. Si aconseguim entendre i controlar aquest proc\u00e9s, els nostres avan\u00e7os podrien tenir un gran impacte en el desenvolupament de noves ter\u00e0pies per a moltes d&#8217;aquestes malalties\u201d.<\/p>\n<p>Les forces mec\u00e0niques i la rigidesa s\u00f3n detectades a trav\u00e9s d&#8217;enlla\u00e7os moleculars d&#8217;escala\u00a0nanom\u00e8trica. Posteriorment, aquestes s\u00f3n integrades primer a escala cel\u00b7lular,\u00a0despr\u00e9s\u00a0a escala de teixit i finalment en els \u00f2rgans i l&#8217;organisme. \u201cEntendre aquest proc\u00e9s a totes aquestes escales \u00e9s un objectiu ambici\u00f3s que requereix harmonitzar\u00a0moltes disciplines\u201d, diu Pere Roca-Cusachs. \u201cMECHANOCONTROL\u00a0persegueix exactament aix\u00f2, reunir un equip de bi\u00f2legs, biof\u00edsics, enginyers, f\u00edsics te\u00f2rics i qu\u00edmics per entendre i controlar la mec\u00e0nica cel\u00b7lular des de l&#8217;escala molecular fins al nivell d&#8217;organisme complet\u201d.<\/p>\n<p>A m\u00e9s del grup de Pere Roca-Cusachs\u00a0en el\u00a0IBEC, tamb\u00e9 participen en el consorci del\u00a0MECHANOCONTROL\u00a0la UPC i el grup\u00a0Mind\u00a0theByte S-L. a Espanya, la\u00a0Universitair Medisch Centrum\u00a0Utrecht\u00a0i\u00a0Noviocell\u00a0B.V a Holanda, el Leibniz-Institut\u00a0a Alemanya i el King\u2019s\u00a0College\u00a0a Londres.<\/p>\n<p>\u201cEntendre la mec\u00e0nica cel\u00b7lular i els seus efectes tamb\u00e9 \u00e9s crucial per al disseny de biomaterials i en aplicacions de medicina regenerativa\u201d afegeix Pere, que ha estat seleccionat recentment <a href=\"https:\/\/ibecbarcelona.eu\/ca\/pere-roca-cusachs-primer-jove-investigador-embo-de-libec\/\" target=\"_blank\">Jove Investigador<\/a> per\u00a0l&#8217;Organitzaci\u00f3 Europea de Biologia Molecular (EMBO, per les seves sigles en angl\u00e8s) i finalista del <a href=\"https:\/\/ibecbarcelona.eu\/ca\/premi-internacional-per-a-pere-roca-cusachs-com-a-lider-emergent-en-ciencia\/\" target=\"_blank\">premi\u00a0Gibco\u00a0al l\u00edder emergent<\/a> convocat per la\u00a0American\u00a0Society\u00a0for Cell\u00a0Biology\u00a0(ASCB).<\/p>\n<p>Entre totes les convocat\u00f2ries del programa\u00a0FET que hi ha hagut fins avui, aquest\u00a0\u00e9s un de solament quatre projectes coordinats a Espanya.<\/p>\n","protected":false},"excerpt":{"rendered":"<h3><img decoding=\"async\" class=\"size-full wp-image-27037 left lazyload\" data-src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2017\/01\/mechanocontrolschema_web.jpg\" alt=\"mechanocontrolschema_web\" width=\"500\" height=\"131\" data-srcset=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2017\/01\/mechanocontrolschema_web.jpg 500w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2017\/01\/mechanocontrolschema_web-300x79.jpg 300w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2017\/01\/mechanocontrolschema_web-230x60.jpg 230w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2017\/01\/mechanocontrolschema_web-150x39.jpg 150w\" data-sizes=\"(max-width: 500px) 100vw, 500px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 500px; --smush-placeholder-aspect-ratio: 500\/131;\" \/>MECHANOCONTROL\u00a0\u00e9s un dels 12 projectes seleccionats entre les 210 sol\u00b7licituds presentades en tota Europa. Amb un finan\u00e7ament de 7 milions d&#8217;euros a 5 anys vista, aquesta subvenci\u00f3 triplica la quantitat que s&#8217;assigna amb cadascuna de les prestigioses beques del\u00a0European\u00a0Research Council\u00a0(ERC).\u00a0 <\/h3>\n<p> Coordinat\u00a0per Pere Roca-Cusachs, investigador principal de l\u2019IBEC\u00a0i professor agregat de la UB, aquest projecte europeu \u00e9s el major assignat a l\u2019IBEC\u00a0fins avui.<\/p>\n","protected":false},"author":4,"featured_media":27039,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[98],"tags":[],"post_formats":[],"class_list":["post-27052","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-institucionals"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>L&#039;IBEC coordinar\u00e0 un projecte de set milions d&#039;euros per desenvolupar ter\u00e0pies contra el c\u00e0ncer i altres malalties - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/libec-coordinara-un-projecte-de-set-milions-deuros-per-desenvolupar-terapies-contra-el-cancer-i-altres-malalties\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"L&#039;IBEC coordinar\u00e0 un projecte de set milions d&#039;euros per desenvolupar ter\u00e0pies contra el c\u00e0ncer i altres malalties - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"MECHANOCONTROL\u00a0\u00e9s un dels 12 projectes seleccionats entre les 210 sol\u00b7licituds presentades en tota Europa. 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