{"id":28179,"date":"2017-03-13T15:41:39","date_gmt":"2017-03-13T14:41:39","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/ca\/?p=28179"},"modified":"2017-03-15T11:45:41","modified_gmt":"2017-03-15T10:45:41","slug":"millores-per-a-la-deteccio-de-pacients-amb-asma-i-malaltia-pulmonar-obstructiva","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/millores-per-a-la-deteccio-de-pacients-amb-asma-i-malaltia-pulmonar-obstructiva\/","title":{"rendered":"Millores per a la detecci\u00f3 de pacients amb asma i malaltia pulmonar obstructiva"},"content":{"rendered":"<h6 class=\"caption\">Imatge: Diagrama de flux del registre de sons respiratoris proposat i an\u00e0lisi CAS posterior.<\/h6>\n<p>&nbsp;<\/p>\n<p>L&#8217;estudi presenta nous algoritmes de processament de senyals per detectar i caracteritzar el CAS, tals com sibil\u00e0ncies, que poden ser diferents entre els asm\u00e0tics amb i sense una resposta broncodilatadora significativa (BDR, de l&#8217;angl\u00e8s <em>bronchodilator response<\/em>). La nova t\u00e8cnica avalua el CAS amb resultats que van m\u00e9s enll\u00e0 que els que actualment proporciona l&#8217;espirometria, que \u00e9s la forma habitual d&#8217;avaluar la BDR en aquests pacients.<\/p>\n<p>Quan l&#8217;obstrucci\u00f3 de les vies respirat\u00f2ries del pacient ha estat confirmada per espirometria, generalment es realitza una prova de BDR per a mesurar la variaci\u00f3 en la limitaci\u00f3 del flux aeri, sent l&#8217;alta variabilitat un dels principals components d&#8217;un diagn\u00f2stic d&#8217;asma. Si b\u00e9 una an\u00e0lisi completa del CAS pot proporcionar informaci\u00f3 clara i complement\u00e0ria sobre la resposta BDR, \u00e9s el criteri BDR est\u00e0ndard actual el que est\u00e0 en dubte, degut principalment a la baixa sensibilitat del m\u00e8tode de detecci\u00f3.<\/p>\n<p>Els pacients asm\u00e0tics que van acudir al Servei de Pneumologia de l&#8217;Hospital Germans Trias i Pujol per fer-se ex\u00e0mens regulars entre el 2011 i el 2015 es van fer la prova de BDR i van participar en l&#8217;estudi d&#8217;an\u00e0lisi i registre de so respiratori.<\/p>\n<p>Utilitzant la nova t\u00e8cnica, els investigadors van trobar canvis significatius en les caracter\u00edstiques del CAS de pacients amb asma, revelant alteracions en l&#8217;obstrucci\u00f3 de les vies respirat\u00f2ries que no van ser detectades per espirometria, i permetent classificar la resposta BDR en tres categories diferenciades.<\/p>\n<p>La nova t\u00e8cnica \u00e9s una eina altament sensible i no invasiva que defineix millor el llindar entre diferents nivells de BDR, a m\u00e9s d&#8217;oferir una aplicaci\u00f3 cl\u00ednica directa per a l&#8217;avaluaci\u00f3 i diagn\u00f2stic de pacients amb malalties pulmonars obstructives.<br \/>\n&#8212;<\/p>\n<p><em><strong>Article de refer\u00e8ncia:<\/strong><\/em> Lozano-Garc\u00eda M, Fiz JA, Mart\u00ednez-Rivera C, Torrents A, Ruiz-Manzano J, Jan\u00e9 R (2017). <a href=\"http:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0171455#sec023\" target=\"_blank\">Novell approach to continuous adventitious respiratory sound analysis for the assessment of bronchodilator response.<\/a> <em>PLoS ONE<\/em> 12(2): i0171455<\/p>\n","protected":false},"excerpt":{"rendered":"<h3> <img class=\"left tama\u00f1o-completo wp-image-28132 lazyload\" data-src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2017\/03\/plosoneraimon.jpg\" alt = \"\" width = \" 400 \"height =\" 249 \" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 400px; --smush-placeholder-aspect-ratio: 400\/249;\" \/> Diverses investigacions dutes a terme a l&#8217;IBEC i  publicades a <em> PlosOne <\/em> ofereixen un pas cap a un millor diagn\u00f2stic en pacients amb asma i malalties pulmonars obstructives. <\/h3>\n<p>El nou enfocament integrat per a l&#8217;an\u00e0lisi del so respiratori adventici continu (CAS, <em>de l&#8217;angl\u00e8s continuous adventitious respiratory sound)<\/em>, desenvolupat pel grup de Recerca i Interpretaci\u00f3 de Senyals Biom\u00e8dics de Raimon Jan\u00e9, en col\u00b7laboraci\u00f3 amb l&#8217;Institut de Recerca Hospital Germans Trias i Pujol (IGTP), facilita la detecci\u00f3 dels casos positius en la pr\u00e0ctica cl\u00ednica.<\/p>\n","protected":false},"author":4,"featured_media":28132,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96],"tags":[],"post_formats":[],"class_list":["post-28179","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-de-recerca"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Millores per a la detecci\u00f3 de pacients amb asma i malaltia pulmonar obstructiva - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/millores-per-a-la-deteccio-de-pacients-amb-asma-i-malaltia-pulmonar-obstructiva\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Millores per a la detecci\u00f3 de pacients amb asma i malaltia pulmonar obstructiva - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Diverses investigacions dutes a terme a l&#039;IBEC i publicades a PlosOne ofereixen un pas cap a un millor diagn\u00f2stic en pacients amb asma i malalties pulmonars obstructives.   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