{"id":57349,"date":"2018-01-19T14:23:51","date_gmt":"2018-01-19T13:23:51","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=57349"},"modified":"2018-01-19T14:56:41","modified_gmt":"2018-01-19T13:56:41","slug":"un-nou-material-promou-la-generacio-de-nous-vasos-sanguinis","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/un-nou-material-promou-la-generacio-de-nous-vasos-sanguinis\/","title":{"rendered":"Un nou material promou la generaci\u00f3 de nous vasos sanguinis"},"content":{"rendered":"<p>Encara que les hMSC poden promoure la neovascularizaci\u00f3 per si mateixes, quan es dipositen en un teixit la seva taxa de superviv\u00e8ncia \u00e9s molt baixa. No obstant aix\u00f2, en encapsular-les en un hidrogel de polietilenglicol biodegradable, la seva viabilitat es mant\u00e9 constant al llarg del temps. <\/p>\n<h6 class=\"caption\" style=\"float: left; width: 39%; padding: 0px 30px 10px 0px;\">Imatge: C\u00e8l\u00b7lules mare mesenquimals humanes formant xarxes dins d&#8217;un hidrogel de polietilenglicol funcionalitzat que cont\u00e9 part\u00edcules de fosfat de calci.<\/h6>\n<p>&nbsp;<br \/>\n&nbsp;<br \/>\n&nbsp;<br \/>\n&nbsp;<br \/>\n&nbsp;<\/p>\n<p>A m\u00e9s a m\u00e9s, les part\u00edcules vitrocer\u00e0miques proporcionen la quantitat correcta i sostinguda de calci necess\u00e0ria per estimular l&#8217;angiog\u00e8nesi, el proc\u00e9s a trav\u00e9s del qual es formen nous vasos sanguinis a partir de vasos preexistents.<\/p>\n<p>&#8220;Aquesta combinaci\u00f3 de hMSCs i part\u00edcules alliberadores de calci representa una nova forma d&#8217;aconseguir el creixement estable de vasos sanguinis, que \u00e9s un factor clau en la regeneraci\u00f3 dels teixits del cos&#8221;, diu la Claudia Navarro, primera autora de l&#8217;estudi i estudiant de doctorat en el grup de l&#8217;IBEC. &#8220;Aquest estudi podria inspirar nous tractaments per a trastorns com la arteriopatia perif\u00e8rica, l&#8217;infart de miocardi o les ferides cr\u00f2niques, tots els quals presenten un subministrament sanguini restringit al teixit que dificulta la seva reparaci\u00f3 i promou la seva degeneraci\u00f3&#8221;.<\/p>\n<p>&#8212;<\/p>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1742706117307651\">Article de refer\u00e8ncia<\/a>: Navarro-Requena, C, Weaver, JD, Clark, AY, Clift, DA, P\u00e9rez-Amodio, S, Casta\u00f1o, \u00d3, Zhou, DW, Garc\u00eda, AJ, &amp; Engel, E. (2017). PEG hydrogel containing calcium-releasing particles and mesenchymal stromal cells promote vessel maturation. Acta Biomater. S1742-7061 (17) 30765-1<\/p>\n","protected":false},"excerpt":{"rendered":"<h3><a href=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2018\/01\/OscarClaudia_ActaBiom_NdP.jpg\"><img decoding=\"async\" class=\"left size-full wp-image-57065 lazyload\" data-src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2018\/01\/OscarClaudia_ActaBiom_NdP.jpg\" alt=\"\" width=\"340\" height=\"276\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 340px; --smush-placeholder-aspect-ratio: 340\/276;\" \/><\/a>En el seu esfor\u00e7 per aconseguir biomaterials funcionals per a la regeneraci\u00f3 de teixits, el grup de l&#8217;IBEC Biomaterials for Regenerative Therapies ha dissenyat un nou material que promou la formaci\u00f3 i maduraci\u00f3 de vasos sanguinis <em>in vivo<\/em>. <\/h3>\n<p>A l&#8217;article, publicat en Acta Biomaterialia a finals de l&#8217;any passat, el grup i els seus col\u00b7laboradors del Georgia Institute of Technology presenten un nou hidrogel implantable que cont\u00e9 c\u00e8l\u00b7lules mare mesenquimals humanes (hMSC, de l&#8217;angl\u00e8s human mesenchymal stromal cells) i micropart\u00edcules alliberadores de calci.<\/p>\n","protected":false},"author":4,"featured_media":57317,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96],"tags":[],"post_formats":[],"class_list":["post-57349","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-de-recerca"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Un nou material promou la generaci\u00f3 de nous vasos sanguinis - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/un-nou-material-promou-la-generacio-de-nous-vasos-sanguinis\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Un nou material promou la generaci\u00f3 de nous vasos sanguinis - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"En el seu esfor\u00e7 per aconseguir biomaterials funcionals per a la regeneraci\u00f3 de teixits, el grup de l&#039;IBEC Biomaterials for Regenerative Therapies ha dissenyat un nou material que promou la formaci\u00f3 i maduraci\u00f3 de vasos sanguinis in vivo.   A l&#039;article, publicat en Acta Biomaterialia a finals de l&#039;any passat, el grup i els seus col\u00b7laboradors del Georgia Institute of Technology presenten un nou hidrogel implantable que cont\u00e9 c\u00e8l\u00b7lules mare mesenquimals humanes (hMSC, de l&#039;angl\u00e8s human mesenchymal stromal cells) i micropart\u00edcules alliberadores de calci.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ibecbarcelona.eu\/ca\/un-nou-material-promou-la-generacio-de-nous-vasos-sanguinis\/\" \/>\n<meta property=\"og:site_name\" content=\"Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"article:published_time\" content=\"2018-01-19T13:23:51+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2018-01-19T13:56:41+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2018\/01\/OscarClaudia_ActaBiom_NdP.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"450\" \/>\n\t<meta property=\"og:image:height\" content=\"449\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"\u00c0ngels L\u00f3pez\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrit per\" \/>\n\t<meta name=\"twitter:data1\" content=\"\u00c0ngels L\u00f3pez\" \/>\n\t<meta name=\"twitter:label2\" content=\"Temps estimat de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minut\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/un-nou-material-promou-la-generacio-de-nous-vasos-sanguinis\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/un-nou-material-promou-la-generacio-de-nous-vasos-sanguinis\\\/\"},\"author\":{\"name\":\"\u00c0ngels L\u00f3pez\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/person\\\/c212c6b589546130be67986b9290e2b8\"},\"headline\":\"Un nou material promou la generaci\u00f3 de nous vasos sanguinis\",\"datePublished\":\"2018-01-19T13:23:51+00:00\",\"dateModified\":\"2018-01-19T13:56:41+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/un-nou-material-promou-la-generacio-de-nous-vasos-sanguinis\\\/\"},\"wordCount\":263,\"publisher\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/un-nou-material-promou-la-generacio-de-nous-vasos-sanguinis\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2018\\\/01\\\/OscarClaudia_ActaBiom_NdP.jpg\",\"articleSection\":[\"Not\u00edcies de recerca\"],\"inLanguage\":\"ca\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/un-nou-material-promou-la-generacio-de-nous-vasos-sanguinis\\\/\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/un-nou-material-promou-la-generacio-de-nous-vasos-sanguinis\\\/\",\"name\":\"Un nou material promou la generaci\u00f3 de nous vasos sanguinis - 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