{"id":6187,"date":"2011-12-07T11:07:48","date_gmt":"2011-12-07T11:07:48","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/new\/exit-de-financament-per-a-dos-projectes-de-libec\/"},"modified":"2015-04-14T14:47:35","modified_gmt":"2015-04-14T14:47:35","slug":"exit-de-financament-per-a-dos-projectes-de-libec","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/exit-de-financament-per-a-dos-projectes-de-libec\/","title":{"rendered":"\u00c8xit de finan\u00e7ament per a dos projectes de l’IBEC"},"content":{"rendered":" En Josep Planell i en George Altankov coordinaran els projectes, que es centraran en solucions per a la pseudoartrosi i les patologies degeneratives de l’esquelet, respectivament. Aquesta \u00e9s la tercera convocat\u00f2ria de projectes d’aquesta iniciativa, i de les 41 propostes rebudes per l’EuroNanoMed, nom\u00e9s 8 varen ser seleccionades per a rebre finan\u00e7ament.<\/p>\n
El projecte \u2018Angiogenic nanostructured materials for non-consolidating bone fractures\u2019 (nAngioFrac), coordinat pel grup Interaccions Bio\/no-bio per a la Medicina Regenerativa d’en Josep Planell a l’IBEC, reuneix a altres quatre socis acad\u00e8mics, hospitalaris i industrials de Fran\u00e7a i Pol\u00f2nia. T\u00e9 com a objectiu desenvolupar bastides nanostructurades biodegradables i bioactives fetes a mida per assegurar l’alliberament correcte de calci, que juga un paper crucial en l’angiogenesi (la formaci\u00f3 de nous vasos sanguinis), per a promoure la reparaci\u00f3 tissular en la pseudoartrosis. Aquesta malaltia es produeix per la consolidaci\u00f3 inadequada d’una fractura \u00f2ssia i de vegades durant el creixement, i resulta en una ‘falsa articulaci\u00f3’.<\/p>\n
Una estrat\u00e8gia important en la regeneraci\u00f3 de teixits \u00e9s el desenvolupament de bastides ‘intel\u00b7ligents’ que puguin estimular les c\u00e8l\u00b7lules progenitores a colonitzar-les i activar el seu comportament natural, resultant en la regeneraci\u00f3 de nou teixit viu i sa. Actualment, una de les principals limitacions de les bastides \u00e9s la manca de vascularitzaci\u00f3 per suportar el creixement i la viabilitat d’aquests teixits regenerats. El consorci nAngioFrac dissenyar\u00e0, desenvolupar\u00e0 i caracteritzar\u00e0 cer\u00e0miques poroses nanostructurades completament inorg\u00e0niques de vidre CaP i bastides de nanofibra h\u00edbrides (de vidre PLA\/CaP), materials capa\u00e7os d’activar l’angiogenesi i la vascularitzaci\u00f3 amb l’alliberament d’ions de calci, i estudiar la seva resposta biol\u00f2gica in vitro i in vivo.<\/p>\n
El segon projecte, \u2018Nanostructured Gel for Cellular Therapy of Degenerative Skeletal Disorders\u2019 (STRUCTGEL), estar\u00e0 coordinat pel responsable del grup Din\u00e0miques Moleculars en l’Interf\u00edcie C\u00e8l\u00b7lula-biomaterial, en George Altankov, i hi participen socis d’Alemanya, Fran\u00e7a i Turquia. Amb l’objectiu d’afrontar les patologies degeneratives dels teixits esquel\u00e8tics com l’osteoartritis i l’osteoporosi, el consorci combinar\u00e0 matarials d’alta funcionalitat i la nanotecnologia avan\u00e7ada epr dissenyar un implant amb propietats \u00faniques que poden influir en la regeneraci\u00f3 tissular en punts concrets.<\/p>\n
La ‘caixa d’eines’ del projecte consisteix en l\u00e0mines d’hidrogel biocompatible amb propietats mec\u00e0niques i temps de degradaci\u00f3 controlats, combinades amb nanofibres per a proporcionar orientaci\u00f3 espacial a les c\u00e8l\u00b7lules. Es faran servir diferents t\u00e8cniques per a incorporar-hi mol\u00e8cules biol\u00f2gicament actives i per bastir l’estructura tridimensional de gel i nanofibres despr\u00e9s de sembrar-hi c\u00e8l\u00b7lules mare mesenquimals. Les l\u00e0mines individuals i les estructures completes d’os i cart\u00edlag es propagaran in vitro per demostrar biocompatibilitat i bioactivitat, i es duran a terme estudis de viabilitat in vivo. <\/p>\n
Sota el pla ERA-NET, els projectes els avalua un comit\u00e8 central de selecci\u00f3, per\u00f2 cada soci del projecte est\u00e0 finan\u00e7at pel seu propi pa\u00eds d’origen. Per tant, tot i que els projectes EuroNanoMed ja han estat seleccionats, cadascun haur\u00e0 de passar una convocat\u00f2ria nacional ad-hoc abans de comen\u00e7ar.<\/p>\n","protected":false},"excerpt":{"rendered":"
![](\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\")
Dos projectes de regeneraci\u00f3 de teixits encap\u00e7alats per l’IBEC han estat seleccionats per l’iniciativa EuroNanoMed de l’ERA-NET de la UE.<\/h3>\n","protected":false},"author":4,"featured_media":6183,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[98],"tags":[],"post_formats":[],"class_list":["post-6187","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-institucionals"],"yoast_head":"\n\u00c8xit de finan\u00e7ament per a dos projectes de l'IBEC - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/exit-de-financament-per-a-dos-projectes-de-libec\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta 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Dos projectes de regeneraci\u00f3 de teixits encap\u00e7alats per l’IBEC han estat seleccionats per l’iniciativa EuroNanoMed de l’ERA-NET de la UE.<\/h3>\n","protected":false},"author":4,"featured_media":6183,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[98],"tags":[],"post_formats":[],"class_list":["post-6187","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-institucionals"],"yoast_head":"\n