{"id":63793,"date":"2018-12-19T11:26:44","date_gmt":"2018-12-19T10:26:44","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=63793"},"modified":"2018-12-11T14:32:38","modified_gmt":"2018-12-11T13:32:38","slug":"el-projecte-de-libec-que-desafia-la-barrera-hematoencefalica-premiat-en-una-convocatoria-altament-competitiva","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/el-projecte-de-libec-que-desafia-la-barrera-hematoencefalica-premiat-en-una-convocatoria-altament-competitiva\/","title":{"rendered":"El projecte de l\u2019IBEC que desafia la barrera hematoencef\u00e0lica premiat en una convocat\u00f2ria altament competitiva"},"content":{"rendered":"<p>\u201cPoder accedir al cervell \u00e9s clau per estudiar el seu funcionament i patologies, aix\u00ed com per fer diagn\u00f2stics i accions amb finalitats terap\u00e8utiques, per\u00f2 la barrera hematoencef\u00e0lica ho impedeix\u201d, diu la S\u00edlvia, professora de recerca a l\u2019ICREA. \u201cQuan s\u2019han desenvolupat portadors de f\u00e0rmacs \u2014o c\u00e0rregues\u2014 molts dels esfor\u00e7os s\u2019han dedicat als aspectes qu\u00edmics i d\u2019enginyeria. Per\u00f2 si en canvi ens centrem en la seva regulaci\u00f3 biol\u00f2gica, podrem complementar amb els coneixements previs disponibles i podrem ser capa\u00e7os d\u2019optimitzar aquests sistemes que poden travessar aquesta barrera de forma m\u00e9s eficient\u201d.<\/p>\n<p>N\u2019\u00e9s un exemple el fet que les c\u00e8l\u00b7lules de la barrera hematoencef\u00e0lica circulen amb les mateixes c\u00e0rregues i hi arriben des del torrent sanguini en dues direccions: cap al seu interior i a trav\u00e9s del seu cos, fet que ha estat en gran part ignorat, aix\u00ed com la seva regulaci\u00f3 biol\u00f2gica, tamb\u00e9 en gran mesura desconeguda. Aix\u00f2 podria ser clau per millorar els sistemes d\u2019administraci\u00f3 de medicaments, de manera que puguin travessar, en comptes d\u2019absorbir-se en la barrera hematoencef\u00e0lica.<\/p>\n<p>Les convocat\u00f2ries <a href=\"http:\/\/www.ciencia.gob.es\/stfls\/eSede\/Ficheros\/2018\/Resolucion_Definitiva_Explora_2017.pdf\" target=\"_blank\" rel=\"noopener\">\u00abExplora Ciencia\u00bb i \u00abExplora Tecnolog\u00eda\u00bb<\/a> han concedit un total de 5 milions d\u2019euros a projectes duts a terme a universitats i centres de recerca. Les subvencions promouen, especialment, projectes que reavaluen paradigmes establerts i cerquen nous conceptes o solucions, aix\u00ed com el desenvolupament d\u2019aplicacions innovadores en diferents disciplines cient\u00edfiques.<\/p>\n","protected":false},"excerpt":{"rendered":"<h3><img decoding=\"async\" class=\"left size-full wp-image-55930 lazyload\" data-src=\"http:\/\/www.ibecbarcelona.eu\/wp-content\/uploads\/2017\/11\/silviamuro1.jpg\" alt=\"\" width=\"500\" height=\"369\" data-srcset=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2017\/11\/silviamuro1.jpg 500w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2017\/11\/silviamuro1-300x221.jpg 300w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2017\/11\/silviamuro1-176x130.jpg 176w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2017\/11\/silviamuro1-150x111.jpg 150w\" data-sizes=\"(max-width: 500px) 100vw, 500px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 500px; --smush-placeholder-aspect-ratio: 500\/369;\" \/><\/a>La prof. S\u00edlvia Muro, l\u00edder del seu grup a l\u2019IBEC, ha rebut un finan\u00e7ament de les convocat\u00f2ries \u00abExplora Ciencia\u00bb i \u00abExplora Tecnolog\u00eda\u00bb 2017 del MINECO.<\/h3>\n<p>\u00c9s la primera subvenci\u00f3 competitiva per a la S\u00edlvia i el seu grup des de que es va incorporar a l\u2019IBEC a finals de 2017, i una dels nom\u00e9s 97 projectes de recerca finan\u00e7ats d\u2019entre les 1.594 propostes presentades, \u00e9s a dir, un percentatge d\u2019\u00e8xit de nom\u00e9s un 6 %.<\/p>\n<p>El projecte \u00abControlling the differential transport of therapeutic cargoes into versus across the BBB (BBB2GATE)\u00bb, t\u00e9 per objectiu desenvolupar portadors de f\u00e0rmacs que puguin travessar la barrera hematoencef\u00e0lica utilitzant les vies naturals que les subst\u00e0ncies corporals fan servir per superar aquest obstacle.<\/p>\n","protected":false},"author":4,"featured_media":63795,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[24,98],"tags":[],"post_formats":[],"class_list":["post-63793","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-institutional-news","category-noticies-institucionals"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>El projecte de l\u2019IBEC que desafia la barrera hematoencef\u00e0lica premiat en una convocat\u00f2ria altament competitiva - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/el-projecte-de-libec-que-desafia-la-barrera-hematoencefalica-premiat-en-una-convocatoria-altament-competitiva\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"El projecte de l\u2019IBEC que desafia la barrera hematoencef\u00e0lica premiat en una convocat\u00f2ria altament competitiva - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"La prof. S\u00edlvia Muro, l\u00edder del seu grup a l\u2019IBEC, ha rebut un finan\u00e7ament de les convocat\u00f2ries \u00abExplora Ciencia\u00bb i \u00abExplora Tecnolog\u00eda\u00bb 2017 del MINECO. \u00c9s la primera subvenci\u00f3 competitiva per a la S\u00edlvia i el seu grup des de que es va incorporar a l\u2019IBEC a finals de 2017, i una dels nom\u00e9s 97 projectes de recerca finan\u00e7ats d\u2019entre les 1.594 propostes presentades, \u00e9s a dir, un percentatge d\u2019\u00e8xit de nom\u00e9s un 6 %. El projecte \u00abControlling the differential transport of therapeutic cargoes into versus across the BBB (BBB2GATE)\u00bb, t\u00e9 per objectiu desenvolupar portadors de f\u00e0rmacs que puguin travessar la barrera hematoencef\u00e0lica utilitzant les vies naturals que les subst\u00e0ncies corporals fan servir per superar aquest obstacle.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ibecbarcelona.eu\/ca\/el-projecte-de-libec-que-desafia-la-barrera-hematoencefalica-premiat-en-una-convocatoria-altament-competitiva\/\" \/>\n<meta property=\"og:site_name\" content=\"Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"article:published_time\" content=\"2018-12-19T10:26:44+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2017\/11\/silviamuro1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"500\" \/>\n\t<meta property=\"og:image:height\" content=\"369\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"\u00c0ngels L\u00f3pez\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrit per\" \/>\n\t<meta name=\"twitter:data1\" content=\"\u00c0ngels L\u00f3pez\" \/>\n\t<meta name=\"twitter:label2\" content=\"Temps estimat de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minut\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/el-projecte-de-libec-que-desafia-la-barrera-hematoencefalica-premiat-en-una-convocatoria-altament-competitiva\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/el-projecte-de-libec-que-desafia-la-barrera-hematoencefalica-premiat-en-una-convocatoria-altament-competitiva\\\/\"},\"author\":{\"name\":\"\u00c0ngels L\u00f3pez\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#\\\/schema\\\/person\\\/c212c6b589546130be67986b9290e2b8\"},\"headline\":\"El projecte de l\u2019IBEC que desafia la barrera hematoencef\u00e0lica premiat en una convocat\u00f2ria altament competitiva\",\"datePublished\":\"2018-12-19T10:26:44+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/el-projecte-de-libec-que-desafia-la-barrera-hematoencefalica-premiat-en-una-convocatoria-altament-competitiva\\\/\"},\"wordCount\":267,\"publisher\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/el-projecte-de-libec-que-desafia-la-barrera-hematoencefalica-premiat-en-una-convocatoria-altament-competitiva\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ibecbarcelona.eu\\\/wp-content\\\/uploads\\\/2017\\\/11\\\/silviamuro1.jpg\",\"articleSection\":[\"Institutional news\",\"Not\u00edcies institucionals\"],\"inLanguage\":\"ca\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/el-projecte-de-libec-que-desafia-la-barrera-hematoencefalica-premiat-en-una-convocatoria-altament-competitiva\\\/\",\"url\":\"https:\\\/\\\/ibecbarcelona.eu\\\/ca\\\/el-projecte-de-libec-que-desafia-la-barrera-hematoencefalica-premiat-en-una-convocatoria-altament-competitiva\\\/\",\"name\":\"El projecte de l\u2019IBEC que desafia la barrera hematoencef\u00e0lica premiat en una convocat\u00f2ria altament competitiva - 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