{"id":77759,"date":"2020-10-02T11:12:50","date_gmt":"2020-10-02T09:12:50","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=77759"},"modified":"2020-11-13T20:27:30","modified_gmt":"2020-11-13T19:27:30","slug":"bioenginyeria-per-lluitar-contra-la-covid-19","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/bioenginyeria-per-lluitar-contra-la-covid-19\/","title":{"rendered":"Bioenginyeria per lluitar contra la Covid-19"},"content":{"rendered":"<p><img decoding=\"async\" class=\"wp-image-77745 alignleft lazyload\" data-src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/10\/minirrinon-ibec-300x300.png\" alt=\"\" width=\"354\" height=\"354\" data-srcset=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/10\/minirrinon-ibec-300x300.png 300w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/10\/minirrinon-ibec-150x150.png 150w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/10\/minirrinon-ibec-45x45.png 45w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/10\/minirrinon-ibec.png 470w\" data-sizes=\"(max-width: 354px) 100vw, 354px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 354px; --smush-placeholder-aspect-ratio: 354\/354;\" \/>La pand\u00e8mia del SARS-CoV-2 s&#8217;ha cobrat la vida de centenars de milers de persones a tot el m\u00f3n i s&#8217;ha convertit en una c\u00e0rrega sense precedents per a la salut p\u00fablica, la nostra societat i l&#8217;economia global. Per proporcionar ter\u00e0pies efectives per a la pand\u00e8mia actual i futurs brots d&#8217;altres tipus de coronavirus, el projecte MAD-CoV-2 ha reunit un equip multidisciplinari d&#8217;investigadors internacionals i empreses que treballaran junts durant quatre anys amb un finan\u00e7ament total de 6.405.168,75\u20ac, dels quals la Comissi\u00f3 Europea aportar\u00e0 un total de 3.749. 668.75 \u20ac i la resta per empreses privades.<\/p>\n<p>El projecte est\u00e0 compost per 9 socis, l&#8217;Institut Nacional de Veterin\u00e0ria a Su\u00e8cia, que lidera el projecte, juntament amb l&#8217;Inserm Transfert SA de Fran\u00e7a, l&#8217;Institut Fuer Molekulare Biotechnologie Gmgh, el Health GmbH i APEIRON Biologics AG, els tres d&#8217;\u00c0ustria, el Justus-Liebig-Universitaet Giessen a Alemanya, STEMCELL Technologies UK LTD del Regne Unit i Vironova AB de Su\u00e8cia. N\u00faria Montserrat i el seu equip s&#8217;uneixen a aquest consorci com un grup reconegut pel seu treball en enginyeria de teixits i desenvolupament d&#8217;organoides humans &#8211; models cel\u00b7lulars que simulen la complexitat d&#8217;aquests \u00f2rgans a la placa de cultiu- a partir de c\u00e8l\u00b7lules mare indu\u00efdes.<\/p>\n<p>MAD-CoV identificar\u00e1 noves dianes terap\u00e8utiques per al desenvolupament r\u00e0pid de nous antivirals contra el SARS-CoV-2 i tamb\u00e9 realitzar\u00e0 una detecci\u00f3 d&#8217;alt rendiment per identificar els factors d&#8217;interacci\u00f3 entre el virus i les c\u00e8l\u00b7lules infectades, que s\u00f3n cr\u00edtics per a la replicaci\u00f3 viral. Com a resultat, ser\u00e0 possible traduir r\u00e0pidament aquest coneixement en noves ter\u00e0pies per combatre el brot actual i de futurs de coronavirus.<\/p>\n<h4><strong>Usant la tecnologia d&#8217;organoides 3D com a model d&#8217;infecci\u00f3<\/strong><\/h4>\n<p>N\u00faria Montserrat i el seu equip se centraran en la caracteritzaci\u00f3 i validaci\u00f3 dels interactors cel\u00b7lulars recentment identificats, com a dianes terap\u00e8utiques mitjan\u00e7ant l&#8217;\u00fas d&#8217;organoides de rony\u00f3. Espec\u00edficament, es treballar\u00e0 en la identificaci\u00f3 de p\u00e8ptids i compostos antivirals que interactuen amb la prote\u00efna S de virus SARS-CoV-2. Gr\u00e0cies a l&#8217;experi\u00e8ncia del consorci en la generaci\u00f3 d&#8217;organoides a partir de c\u00e8l\u00b7lules mare adultes i de c\u00e8l\u00b7lules mare pluripotencials, s&#8217;avaluar\u00e0 l&#8217;efectivitat dels compostos mitjan\u00e7ant l&#8217;\u00fas de models d&#8217;organoides de pulm\u00f3, c\u00f2lon i rony\u00f3.<\/p>\n<p>A m\u00e9s, es duran a terme m\u00e9s investigacions per prevenir possibles futures epid\u00e8mies causades per altres coronavirus per identificar el tal\u00f3 d&#8217;Aquil\u00b7les com\u00fa i, per tant, desenvolupar medicaments i estrat\u00e8gies disruptives per a combatre-les.<\/p>\n<p>Aquest projecte va n\u00e9ixer com a part de la resposta de la UE a l&#8217;actual pand\u00e8mia causada pel coronavirus com a part del programa H2020. La &#8220;Iniciativa de Medicaments Innovadors&#8221; (IMI) va anunciar aquesta nova convocat\u00f2ria d&#8217;una inversi\u00f3 de 45 milions d&#8217;euros en fons d&#8217;investigaci\u00f3 per a aquells equips que poden demostrar la seva capacitat per desenvolupar proves i\/o tractaments per a la COVID-19 que puguin arribar al mercat el m\u00e9s r\u00e0pid possible. Finalment, es van presentar 144 projectes i degut a l\u2019alta qualitat de les propostes rebudes, l\u2019IMI va decidir augmentar el finan\u00e7ament fins als 72 milions d\u2019euros, gr\u00e0cies a la participaci\u00f3 de les empreses de l\u2019<a href=\"https:\/\/www.efpia.eu\/about-us\/\" target=\"_blank\" rel=\"noopener noreferrer\">EFPIA<\/a> i d\u2019altres organitzacions, que aniran destinats als 8 projectes seleccionats.<\/p>\n","protected":false},"excerpt":{"rendered":"<h3>Ahir va tenir lloc la reuni\u00f3 de llan\u00e7ament del projecte europeu MAD-CoV 2 en el que participa el grup dirigit per la professora d&#8217;investigaci\u00f3 ICREA N\u00faria Montserrat a l&#8217;IBEC.<\/h3>\n<p> Sota el nom d'&#8221;Enfocaments moderns per al desenvolupament d&#8217;antivirals contra el SARS-CoV 2&#8243; (MAD-CoV 2 per les seves sigles en angl\u00e8s), el projecte se centrar\u00e0 a desenvolupar i proporcionar eines terap\u00e8utiques per a l&#8217;actual brot de COVID-19. <\/p>\n","protected":false},"author":4,"featured_media":77745,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[98],"tags":[1244,866,923],"post_formats":[],"class_list":["post-77759","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-institucionals","tag-bioengineering-ca","tag-bioenginyeria-ca","tag-covid-ca"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Bioenginyeria per lluitar contra la Covid-19 - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/bioenginyeria-per-lluitar-contra-la-covid-19\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bioenginyeria per lluitar contra la Covid-19 - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Ahir va tenir lloc la reuni\u00f3 de llan\u00e7ament del projecte europeu MAD-CoV 2 en el que participa el grup dirigit per la professora d&#039;investigaci\u00f3 ICREA N\u00faria Montserrat a l&#039;IBEC. 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