{"id":80625,"date":"2020-12-18T17:56:20","date_gmt":"2020-12-18T16:56:20","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=80625"},"modified":"2020-12-23T11:43:36","modified_gmt":"2020-12-23T10:43:36","slug":"libec-participa-en-un-projecte-europeu-amb-lobjectiu-daccelerar-la-investigacio-clinica-per-a-la-discapacitat-visual","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/libec-participa-en-un-projecte-europeu-amb-lobjectiu-daccelerar-la-investigacio-clinica-per-a-la-discapacitat-visual\/","title":{"rendered":"L&#8217;IBEC participa en un projecte europeu amb l&#8217;objectiu d&#8217;accelerar la investigaci\u00f3 cl\u00ednica per a la discapacitat visual"},"content":{"rendered":"<p><img decoding=\"async\" class=\"alignleft size-large wp-image-80482 lazyload\" data-src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/12\/ecabox-1024x1024.png\" alt=\"\" width=\"900\" height=\"900\" data-srcset=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/12\/ecabox-1024x1024.png 1024w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/12\/ecabox-300x300.png 300w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/12\/ecabox-150x150.png 150w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/12\/ecabox-768x768.png 768w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/12\/ecabox-45x45.png 45w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2020\/12\/ecabox.png 1298w\" data-sizes=\"(max-width: 900px) 100vw, 900px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 900px; --smush-placeholder-aspect-ratio: 900\/900;\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><span data-contrast=\"auto\">La discapacitat visual afecta m\u00e9s de 250 milions de persones a tot el m\u00f3n, i trenta-sis milions de persones s\u00f3n cegues. La degeneraci\u00f3 de la retina sovint \u00e9s incurable i l&#8217;envelliment de la poblaci\u00f3 a tot el m\u00f3n \u00e9s un desafiament social i econ\u00f2mic important.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">A causa de les limitacions tecnol\u00f2giques actuals, els ulls nom\u00e9s poden mantenir-se a 4<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u00baC durant un per\u00edode de 48 hores abans d&#8217;una degradaci\u00f3 irreversible. Aix\u00f2 limita en gran m<\/span><span data-contrast=\"auto\">anera<\/span><span data-contrast=\"auto\">\u00a0el seu \u00fas per a l&#8217;experimentaci\u00f3, particularment per provar l&#8217;efectivitat de nous medicaments i tractaments.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Ara, un consorci interdisciplinari compost per set centres de recerca internacionals treballar\u00e0 per trobar noves solucions en el marc del Projecte Europeu\u00a0<\/span><span data-contrast=\"auto\">ECaBOX<\/span><span data-contrast=\"auto\">. El projecte ha estat premiat amb 3,5 milions d&#8217;euros pel programa d&#8217;investigaci\u00f3 &#8220;<\/span><span data-contrast=\"auto\">Future<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">and<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Emerging<\/span><span data-contrast=\"auto\">\u00a0Technologies Open\u00a0<\/span><span data-contrast=\"auto\">research<\/span><span data-contrast=\"auto\">\u00a0FET-Open&#8221; de la Uni\u00f3 Europea, que finan\u00e7a tecnologies radicalment noves.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">El projecte\u00a0<\/span><span data-contrast=\"auto\">ECaBOX<\/span><span data-contrast=\"auto\">\u00a0ser\u00e0 coordinat per Pia\u00a0<\/span><span data-contrast=\"auto\">Cosma<\/span><span data-contrast=\"auto\">\u00a0al CRG en col\u00b7laboraci\u00f3 amb altres dos centres de recerca catalans: Ricardo\u00a0<\/span><span data-contrast=\"auto\">Casaroli<\/span><span data-contrast=\"auto\">\u00a0de la Universitat de Barcelona i\u00a0<\/span><b><span data-contrast=\"auto\">N\u00faria Montserrat, professora d&#8217;investigaci\u00f3 ICREA i l\u00edder de grup de l&#8217;Institut de Bioenginyeria de Catalunya (IBEC).<\/span><\/b><span data-contrast=\"auto\">\u00a0Altres col\u00b7laboradors internacionals inclouen King &#8216;s\u00a0<\/span><span data-contrast=\"auto\">College<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">London<\/span><span data-contrast=\"auto\">\u00a0(KCL) al Regne Unit, l&#8217;Associaci\u00f3 per a l&#8217;Avan\u00e7 de l&#8217;Enginyeria de Teixits i Tecnologies i Ter\u00e0pies Basades en C\u00e8l\u00b7lules (A4TEC) a Portugal, AFERETICA a It\u00e0lia i la Universitat de\u00a0<\/span><span data-contrast=\"auto\">BarIlan<\/span><span data-contrast=\"auto\">\u00a0(BIU) en Israel.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<h2><strong><span lang=\"ES-ES\" xml:lang=\"ES-ES\" data-contrast=\"auto\"> <span lang=\"CA-ES\" xml:lang=\"CA-ES\" data-contrast=\"auto\">El Projecte\u00a0<\/span><span lang=\"CA-ES\" xml:lang=\"CA-ES\" data-contrast=\"auto\">ECaBOX<\/span><span lang=\"CA-ES\" xml:lang=\"CA-ES\" data-contrast=\"auto\">\u00a0i el dispositiu<\/span>\u00a0<\/span><\/strong><\/h2>\n<p><span data-contrast=\"auto\">Si b\u00e9 els aven\u00e7os en\u00a0<\/span><span data-contrast=\"auto\">organoides<\/span><span data-contrast=\"auto\">\u00a0humans (models cel\u00b7lulars que simulen la complexitat d&#8217;aquests \u00f2rgans a la placa de cultiu) estan imitant amb \u00e8xit la funci\u00f3 de l&#8217;ull, encara presenten limitacions a<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">l<\/span><span data-contrast=\"auto\">\u2019<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">encapsular la complexitat fisiol\u00f2gica de l&#8217;ull,\u00a0<\/span><span data-contrast=\"auto\">aix\u00ed\u00a0<\/span><span data-contrast=\"auto\">com el<\/span><span data-contrast=\"auto\">\u00a0seu<\/span><span data-contrast=\"auto\">\u00a0sistem<\/span><span data-contrast=\"auto\">a<\/span><span data-contrast=\"auto\">\u00a0immun<\/span><span data-contrast=\"auto\">itari<\/span><span data-contrast=\"auto\">, vascular i metab\u00f2lic.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">El nou m\u00e8tode desenvolupat dins el projecte\u00a0<\/span><span data-contrast=\"auto\">ECaBOX<\/span><span data-contrast=\"auto\">\u00a0evitar\u00e0 aquestes limitacions revivint els ulls i mantenint-<\/span><span data-contrast=\"auto\">los\u00a0<\/span><span data-contrast=\"auto\">sans durant a<\/span><span data-contrast=\"auto\">l menys un mes, ajudant els investigadors a avaluar l&#8217;efic\u00e0cia, efici\u00e8ncia i seguretat de les noves ter\u00e0pies regeneratives i les proves de f\u00e0rmacs. Utilitza<\/span><span data-contrast=\"auto\">r<\/span><span data-contrast=\"auto\">\u00a0ulls ressuscitats tamb\u00e9 pot eludir diverses restriccions \u00e8tiques de les proves\u00a0<\/span><span data-contrast=\"auto\">precl\u00edniques<\/span><span data-contrast=\"auto\">\u00a0amb animals, aix\u00ed com l&#8217;experimentaci\u00f3 amb humans.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">El dispositiu, anomenat\u00a0<\/span><span data-contrast=\"auto\">ECaBox<\/span><span data-contrast=\"auto\">, ser\u00e0 una caixa c\u00fabica transparent que imitar\u00e0 les condicions de l&#8217;ull hum\u00e0 viu, mantenint la temperatura de l&#8217;ull i els nivells de pH mentre\u00a0<\/span><span data-contrast=\"auto\">evita els co\u00e0guls de sang i elimina les deixalles metab\u00f2li<\/span><span data-contrast=\"auto\">que<\/span><span data-contrast=\"auto\">s i les toxines. S&#8217;espera que es construeixi un prototip d&#8217;hora del dispositiu a finals de 2023.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0<\/p>\n<h3>Nuria Montserrat y su equipo en el IBEC participan en un consorcio internacional que tiene como objetivo desarrollar un dispositivo para acelerar la investigaci\u00f3n cl\u00ednica de enfermedades oculares, a partir de ojos humanos de donantes. <\/h3>\n","protected":false},"author":4,"featured_media":80483,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[98],"tags":[708,1123],"post_formats":[],"class_list":["post-80625","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-institucionals","tag-collaboracions-cliniques","tag-nuria-montserrat-ca-2"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>L&#039;IBEC participa en un projecte europeu amb l&#039;objectiu d&#039;accelerar la investigaci\u00f3 cl\u00ednica per a la discapacitat visual - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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