{"id":80978,"date":"2021-01-21T09:41:30","date_gmt":"2021-01-21T08:41:30","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=80978"},"modified":"2021-01-21T09:54:57","modified_gmt":"2021-01-21T08:54:57","slug":"forces-mecaniques-la-meitat-de-lalfabet-per-a-entendre-la-vida","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/forces-mecaniques-la-meitat-de-lalfabet-per-a-entendre-la-vida\/","title":{"rendered":"Forces mec\u00e0niques, la meitat de l’alfabet per a entendre la vida"},"content":{"rendered":"
\"\"
Embri\u00f3 de peix zebra. Cr\u00e8dits: Philipp Keller \/ HHMI Janelia Research Campus<\/span>\u00a0<\/span><\/figcaption><\/figure>\n

Durant les \u00faltimes dues d\u00e8cades, m\u00e9s cient\u00edfics han comen\u00e7at a prestar atenci\u00f3 a la import\u00e0ncia de la f\u00edsica en el desenvolupament d’\u00f2rgans i organismes. Els embrions en desenvolupament, per exemple, els d’aquest peix zebra de la imatge, depenen de les forces f\u00edsiques per esculpir<\/span>-se<\/span> a mesura que creixen. Per tant, els investigadors han comen\u00e7at a definir els mecanismes pels quals les c\u00e8l\u00b7lules detecten, responen i generen forces.<\/span>\u00a0<\/span><\/p>\n

Ara, l’escriptora cient\u00edfica <\/span>Amber<\/span> Dance<\/span>, ha preguntat a alguns dels investigadors m\u00e9s influents en el camp de la <\/span>mecanobiolog\u00eda<\/span> i ha escrit un article a la revista <\/span>Nature<\/span> sota el t\u00edtol de <\/span>\u00abLes forces secretes que estrenyen i donen forma a la vida<\/span><\/a>\u00ab.<\/span>\u00a0<\/span><\/p>\n

Un dels reconeguts experts consultats per <\/span>Amber<\/span> Dance<\/span> \u00e9s <\/span>Xavier Trepat<\/span><\/a>, <\/span>mecanobi<\/span>\u00f2leg<\/span> i enginyer de l’Institut de Bioenginyeria de Catalunya, on lidera el grup de recerca <\/span>Din\u00e0mica Integrativa de c\u00e8l\u00b7lules i teixits<\/span><\/a>.<\/span>\u00a0<\/span><\/p>\n

En paraules de Xavier Trepat, un dels investigadors m\u00e9s destacats en el camp: \u00abConsiderar nom\u00e9s gens i biomol\u00e8cules \u00e9s com si estiguessis tractant d’escriure un llibre amb <\/span>nom\u00e9s<\/span> la meitat de les lletres de l’alfabet\u00bb.<\/span>\u00a0<\/span><\/p>\n

De fet, Xavier Trepat, professor d’investigaci\u00f3 ICREA i l\u00edder de grup de l’IBEC, coneix molt b\u00e9 la import\u00e0ncia de la mec\u00e0nica en els sistemes biol\u00f2gics. Ell i el seu equip han desenvolupat diverses tecnologies per observar i mesurar a escala <\/span>nanom\u00e8trica<\/span> les propietats de les c\u00e8l\u00b7lules. Al fer-ho, Trepat i els seus col\u00b7legues han contribu\u00eft a una millor comprensi\u00f3 dels mecanismes biof\u00edsics fonamentals subjacents a la interacci\u00f3 i la comunicaci\u00f3 cel\u00b7lular. En el cam\u00ed, Trepat i els seus col\u00b7legues han informat de descobriments sorprenents com <\/span>c\u00e8l\u00b7lules s<\/span>u<\/span>perel\u00e0stiques<\/span><\/a>.<\/span>\u00a0<\/span><\/p>\n

Per\u00f2 Trepat tamb\u00e9 s’ha centrat en el paper de la f\u00edsica a les malalties. Com <\/span>se<\/span> senyala <\/span>en l’article <\/span>recent <\/span>publicat a<\/span> Nature<\/span><\/i>, les propietats mec\u00e0niques dels teixits tamb\u00e9 juguen un paper en el creixement cel\u00b7lular anormal, com en el c\u00e0ncer. En paraules de Trepat \u00abLa rigidesa fa que les c\u00e8l\u00b7lules canceroses siguin m\u00e9s malignes\u00bb.<\/span>\u00a0<\/span><\/p>\n

Aix\u00ed, les forces mec\u00e0niques determinen entitats biol\u00f2giques com ara c\u00e8l\u00b7lules i \u00f2rgans, tant en salut com en malaltia i per tant, com assenyala Trepat en un <\/span>tuit<\/span><\/a> recent vinculat a l’article de <\/span>Nature<\/span>: \u00abEntendre una c\u00e8l\u00b7lula sense f\u00edsica \u00e9s com intentar escriure un llibre amb nom\u00e9s la meitat de les lletres de l’alfabet\u00bb.<\/span>\u00a0<\/span><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Xavier Trepat i experts internacionals ens recorden en un article publicat al Journal Nature per l’escriptora cient\u00edfica Amber Dance, el paper crucial de la f\u00edsica per comprendre entitats biol\u00f2giques com c\u00e8l\u00b7lules i \u00f2rgans, tant en la salut com en la malaltia. En paraules de Trepat: \u00abEntendre una c\u00e8l\u00b7lula sense f\u00edsica \u00e9s com intentar escriure un llibre amb sol la meitat de les lletres de l’alfabet\u00bb. <\/h3>\n","protected":false},"author":4,"featured_media":80975,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96],"tags":[1367,1366,1143],"post_formats":[],"class_list":["post-80978","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-de-recerca","tag-cellules-superelastiques","tag-forces-mecaniques","tag-xavier-trepat-ca"],"yoast_head":"\nForces mec\u00e0niques, la meitat de l'alfabet per a entendre la vida - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/mechanical-forces-half-of-the-alphabet-to-understand-life\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Forces mec\u00e0niques, la meitat de l'alfabet per a entendre la vida - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Xavier Trepat i experts internacionals ens recorden en un article publicat al Journal Nature per l'escriptora cient\u00edfica Amber Dance, el paper crucial de la f\u00edsica per comprendre entitats biol\u00f2giques com c\u00e8l\u00b7lules i \u00f2rgans, tant en la salut com en la malaltia. 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