{"id":82361,"date":"2021-03-02T14:33:26","date_gmt":"2021-03-02T13:33:26","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/?p=82361"},"modified":"2021-03-02T20:56:10","modified_gmt":"2021-03-02T19:56:10","slug":"el-nou-programa-fundacio-la-caixa-bist-chemical-biology-impulsa-un-hub-per-al-disseny-de-nous-farmacs-a-barcelona","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/el-nou-programa-fundacio-la-caixa-bist-chemical-biology-impulsa-un-hub-per-al-disseny-de-nous-farmacs-a-barcelona\/","title":{"rendered":"El nou programa Fundaci\u00f3 \u201cla Caixa\u201d \u2013 BIST Chemical Biology impulsa un hub per al disseny de nous f\u00e0rmacs a Barcelona"},"content":{"rendered":"<p>La <a href=\"https:\/\/fundacionlacaixa.org\">Fundaci\u00f3 \u201cla Caixa\u201d<\/a> i el <a href=\"https:\/\/bist.eu\">Barcelona Institute of Science and Technology<\/a> (BIST), llancen el programa Fundaci\u00f3 &#8220;la Caixa&#8221; &#8211; BIST Chemical Biology destinat a impulsar la recerca en biologia qu\u00edmica i l\u2019obtenci\u00f3 de nous medicaments. Dos centres, <a href=\"http:\/\/www.ibecbarcelona.eu\/\">l\u2019Institut de Bioenginyeria de Catalunya<\/a> i <a href=\"https:\/\/www.irbbarcelona.org\/en\">l\u2019Institut de Recerca Biom\u00e8dica de Barcelona<\/a>, s\u2019uneixen a aquesta iniciativa, amb la incorporaci\u00f3 de dues noves l\u00edders de grup, les doctores Irene Marco-Rius (IBEC) i Cristina Mayor-Ruiz (IRB Barcelona), que dirigiran els seus propis grups d\u2019investigaci\u00f3 en biologia qu\u00edmica en els seus respectius centres, tot establint un marc de col\u00b7laboraci\u00f3 en recerca multidisciplin\u00e0ria.<\/p>\n<p>Els principals objectius del projecte s\u00f3n posar en marxa un <strong>potent programa de recerca en aquesta disciplina<\/strong> i <strong>atraure talent<\/strong>, tot creant un <em>hub<\/em> de biologia qu\u00edmica a la ciutat de Barcelona. Amb la col\u00b7laboraci\u00f3 dels dos centres referents, l\u2019IBEC i l\u2019IRB Barcelona, s\u2019afavoreix la recerca multidisciplin\u00e0ria i l\u2019establiment d\u2019un important nucli en aquesta ciutat, obrint la porta a noves col\u00b7laboracions entre centres i nous projectes en biologia qu\u00edmica.<\/p>\n<blockquote><p><strong>Amb aquest programa la Fundaci\u00f3 \u201cla Caixa\u201d fa un pas m\u00e9s en l\u2019aposta decidida per assegurar que els resultats de la investigaci\u00f3 en salut es traslladin a la societat. Des de fa m\u00e9s de 30 anys la instituci\u00f3 aposta per la recerca d\u2019excel\u00b7l\u00e8ncia, conven\u00e7uts que impulsar la investigaci\u00f3 en salut \u00e9s invertir en el benestar de les persones. Aix\u00ed, el suport a programes d\u2019investigaci\u00f3 i la innovaci\u00f3 esdev\u00e9 imprescindible per potenciar un ecosistema que fomenti la cerca de noves solucions i doni resposta a grans reptes actuals i futurs en l\u2019\u00e0mbit de la salut\u201d, assegura \u00c0ngel Font, Director Corporatiu d\u2019Investigaci\u00f3 i Salut de la Fundaci\u00f3 \u201dla Caixa.<\/strong><\/p><\/blockquote>\n<p><img decoding=\"async\" class=\"wp-image-82351 alignleft lazyload\" data-src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2021\/03\/Irene_Marco_1-scaled.jpg\" alt=\"\" width=\"464\" height=\"310\" data-srcset=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2021\/03\/Irene_Marco_1-scaled.jpg 2560w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2021\/03\/Irene_Marco_1-300x200.jpg 300w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2021\/03\/Irene_Marco_1-1024x683.jpg 1024w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2021\/03\/Irene_Marco_1-768x512.jpg 768w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2021\/03\/Irene_Marco_1-1536x1024.jpg 1536w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2021\/03\/Irene_Marco_1-2048x1365.jpg 2048w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2021\/03\/Irene_Marco_1-150x100.jpg 150w\" data-sizes=\"(max-width: 464px) 100vw, 464px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 464px; --smush-placeholder-aspect-ratio: 464\/310;\" \/>Per la seva banda, la <strong>Dra. Irene Marco-Rius<\/strong> explica que el seu grup es focalitzar\u00e0 en el desenvolupament de tecnologies innovadores d\u2019imatge molecular per diagnosticar malalties i avaluar la resposta al tractament de manera preco\u00e7. <em>\u201cLes c\u00e8l\u00b7lules del nostre cos s\u2019adapten r\u00e0pidament al seu entorn i canvien la manera com aconsegueixen els nutrients i l\u2019energia que els cal per sobreviure. El meu grup treballa amb una tecnologia que ens permet estudiar aquestes reaccions qu\u00edmiques dins el nostre cos, o fent servir bioenginyeria de teixits, i trobar marcadors de malalties o de resposta a un f\u00e0rmac abans que es produeixin canvis anat\u00f2mics. <\/em><\/p>\n<p><em>Per exemple, podem distingir entre c\u00e8l\u00b7lules cancer\u00edgenes i c\u00e8l\u00b7lules sanes dins el cos fent servir un aparell de resson\u00e0ncia magn\u00e8tica sense necessitat de fer una bi\u00f2psia i sense dolor.\u201d <\/em>La Dra. Marco-Rius comenta que \u201c<em>la recerca biom\u00e8dica \u00e9s molt multidisciplin\u00e0ria, i els grans aven\u00e7os necessiten d\u2019un nucli d\u2019excel\u00b7l\u00e8ncia que fomenti la col\u00b7laboraci\u00f3 i l\u2019intercanvi de coneixement. En aquest sentit, <\/em><em>Barcelona i el programa de la Fundaci\u00f3 \u201cla Caixa\u201d i el BIST s\u00f3n <\/em><em>una pe\u00e7a clau perqu\u00e8 puguem seguir fent recerca d\u2019avantguarda<\/em>.\u201d<\/p>\n<p>Per altra banda<strong>, la Dra. Mayor-Ruiz<\/strong> subratlla que <em>\u201cla biologia qu\u00edmica t\u00e9 un gran potencial traslacional, especialment per a la producci\u00f3 de nous f\u00e0rmacs, pel que resulta especialment interessant impulsar un nucli potent d\u2019aquesta disciplina en un entorn com Barcelona, amb una important ind\u00fastria farmac\u00e8utica\u201d<\/em>. El nou laboratori de Cristina Mayor-Ruiz treballa en degradaci\u00f3 dirigida de prote\u00efnes, una t\u00e8cnica innovadora amb aplicacions terap\u00e8utiques. <em>\u201cEl que fem \u00e9s utilitzar entitats qu\u00edmiques (f\u00e0rmacs) per a reprogramar mecanismes que les nostres c\u00e8l\u00b7lules empren de forma natural per a degradar prote\u00efnes. Nosaltres redirigim aquests mecanismes contra prote\u00efnes que tenen inter\u00e8s terap\u00e8utic, per exemple en el tractament del c\u00e0ncer i, en concret, en el de p\u00e0ncrees, per al qual no hi ha pr\u00e0cticament cap tractament disponible actualment\u201d.<\/em><\/p>\n<p>&nbsp;<\/p>\n<h2><strong>Biologia qu\u00edmica, una disciplina en auge<\/strong><\/h2>\n<p>La biologia qu\u00edmica \u00e9s la ci\u00e8ncia que estudia el comportament de petites mol\u00e8cules en sistemes vius, combinant les t\u00e8cniques quantitatives de la qu\u00edmica amb la import\u00e0ncia m\u00e8dica de la biologia. Una de les metes de la biologia qu\u00edmica \u00e9s l\u2019obtenci\u00f3 de <strong>nous medicaments<\/strong>, tal com descriu el Prof. Herbert Waldmann de l\u2019Institut Max Planck de Fisiologia Molecular: \u201c<em>La biologia qu\u00edmica t\u00e9 la capacitat inherent de contribuir a la millora de la vida humana, en particular inspirant i alimentant el desenvolupament de medicaments nous i millors, i millorant la nutrici\u00f3 humana.&#8221;<\/em><\/p>\n<p>Per\u00f2 tot i que en pa\u00efsos com Alemanya, on es troba l\u2019institut del Prof. Waldmann, la biologia qu\u00edmica \u00e9s una important disciplina d\u2019investigaci\u00f3, en el nostre pa\u00eds nom\u00e9s trobem grups de recerca a\u00efllats treballant-hi. D\u2019aqu\u00ed la import\u00e0ncia del programa Fundaci\u00f3 \u201cla Caixa\u201d \u2013 BIST Chemical Biology, que vol potenciar la investigaci\u00f3 en biologia qu\u00edmica en una ciutat, Barcelona, amb un potent sector biofarmac\u00e8utic. El programa de biologia qu\u00edmica, promogut pel BIST i la Fundaci\u00f3 \u201cla Caixa\u201d, \u00e9s una gran oportunitat d\u2019aprofitar infraestructures ja establertes a Barcelona per a avan\u00e7ar en aquest camp de manera local i internacional, establint una nova l\u00ednia de recerca multidisciplin\u00e0ria, inexistent en el nostre pa\u00eds.<\/p>\n<h2><strong>Un programa per impulsar el talent jove<\/strong><\/h2>\n<p>El programa ha perm\u00e8s la creaci\u00f3 de dues noves posicions de <em>Junior Group Leaders<\/em>, per a les quals han estat seleccionades les investigadores <strong>Cristina Mayor-Ruiz<\/strong> (IRB Barcelona) i <strong>Irene Marco-Rius<\/strong> (IBEC). La selecci\u00f3 de la <a href=\"https:\/\/www.irbbarcelona.org\/en\/profile\/cristina-mayor-ruiz\">Dra. Cristina Mayor-Ruiz<\/a> compleix amb un dels objectius del programa, l\u2019<strong>atracci\u00f3 de talent<\/strong>, ja que es tracta d\u2019una investigadora jove per\u00f2 que compta ja amb un important curr\u00edculum en biologia qu\u00edmica. El 2017 va obtenir el doctorat al Centre Nacional d\u2019Investigacions Oncol\u00f2giques (CNIO) de Madrid, per seguir despr\u00e9s la seva carrera al Centre de Recerca en Medicina Molecular (CeMM) de Viena, amb el suport de les beques postdoctorals EMBO i Marie Curie.<\/p>\n<p>La <a href=\"https:\/\/ibecbarcelona.eu\/member\/1553\/Irene%20Marco%20Rius\/\">Dra. Irene Marco<\/a>-Rius, per la seva part, representa un cas d\u2019excel\u00b7l\u00e8ncia en recerca amb experi\u00e8ncia internacional. Amb un m\u00e0ster a la Universitat de Heidelberg (Alemanya \u2013 beca de postgrau de \u201cla Caixa\u201d-DAAD), es va doctorar per la Universitat de Cambridge el 2014 (Regne Unit \u2013 beca Marie Curie ITN) i, despr\u00e9s d\u00b4un per\u00edode postdoctoral a la Universitat de Calif\u00f2rnia-San Francisco (EEUU) i el Centre d\u2019Investigaci\u00f3 pel C\u00e0ncer a Cambridge, es va incorporar a l\u00b4IBEC al 2018 com a investigadora dins del grup \u201cBiosensors per a Bioenginyeria\u201d (beca postdoctoral Junior Leader de la Caixa). Des del 2020, la Dra. Marco-Rius coordina el projecte europeu Bloc.<\/p>\n<p>La nova posici\u00f3 de la Dra. Marco-Rius \u00e9s tamb\u00e9 un significatiu cas d\u2019\u00e8xit del programa de lideratge <a href=\"https:\/\/bist.eu\/talent\/mothers-of-science\/\"><strong>To the Mothers of Science<\/strong><\/a>, impulsat pel BIST. La finalitat d\u2019aquest programa \u00e9s oferir suport a les mares que treballen en recerca per avan\u00e7ar en els seus camps d\u2019investigaci\u00f3 i dotar-les d\u2019eines per a assolir una posici\u00f3 de lideratge. Irene Marco-Rius va ser una de les guanyadores de l\u2019edici\u00f3 de 2020 i estrenar\u00e0 aquest any el seu laboratori de biologia qu\u00edmica a l\u2019IBEC.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<h3>La Fundaci\u00f3 \u201cla Caixa\u201d i el BIST creen el programa Chemical Biology per impulsar dos nous grups de recerca puntera a l\u2019IBEC i a l\u00b4IRB, dos centres membres del BIST. La iniciativa pret\u00e9n captar talent en l\u2019\u00e0mbit de la biologia qu\u00edmica i alhora promoure la creaci\u00f3 d\u2019un ecosistema que fomenti la investigaci\u00f3 d\u2019excel\u00b7l\u00e8ncia per millorar la salut de les persones.<\/h3>\n","protected":false},"author":4,"featured_media":82355,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[98],"tags":[1122],"post_formats":[],"class_list":["post-82361","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-institucionals","tag-irene-marco-rius-ca"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>El nou programa Fundaci\u00f3 \u201cla Caixa\u201d \u2013 BIST Chemical Biology impulsa un hub per al disseny de nous f\u00e0rmacs a Barcelona - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/el-nou-programa-fundacio-la-caixa-bist-chemical-biology-impulsa-un-hub-per-al-disseny-de-nous-farmacs-a-barcelona\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"El nou programa Fundaci\u00f3 \u201cla Caixa\u201d \u2013 BIST Chemical Biology impulsa un hub per al disseny de nous f\u00e0rmacs a Barcelona - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"La Fundaci\u00f3 \u201cla Caixa\u201d i el BIST creen el programa Chemical Biology per impulsar dos nous grups de recerca puntera a l\u2019IBEC i a l\u00b4IRB, dos centres membres del BIST. 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