{"id":87504,"date":"2021-09-30T16:27:06","date_gmt":"2021-09-30T14:27:06","guid":{"rendered":"https:\/\/ibecbarcelona.eu\/?p=87504"},"modified":"2021-10-04T11:30:25","modified_gmt":"2021-10-04T09:30:25","slug":"la-campanya-faster-future-contra-el-parkinson-culmina-amb-nous-avencos-cientifics","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/la-campanya-faster-future-contra-el-parkinson-culmina-amb-nous-avencos-cientifics\/","title":{"rendered":"La campanya Faster Future contra el Parkinson culmina amb nous aven\u00e7os cient\u00edfics"},"content":{"rendered":"

\"\"<\/p>\n

La malaltia de Parkinson \u00e9s una <\/span>patologia <\/span>neurodegenerativa, cr\u00f2nica i incurable, que afecta entre 7 i 10 milions de pacients al m\u00f3n. El Parkinson afecta principalment a persones majors de 65 anys (en un 70% dels casos), encara que al voltant d’un 15% dels afectats \u00e9s menor de 50, i \u00e9s una malaltia que afecta el sistema nervi\u00f3s central, provocant s\u00edmptomes com trastorns en l’equilibri i en caminar, tremolors i rigidesa muscular.<\/span>
\n<\/span>Actualment es desconeixen les causes de la malaltia de\u00a0Parkinson\u00a0i, per tant, tamb\u00e9 els mecanismes exactes per prevenir-la, per\u00f2 s\u00ed que es coneix un element clau que frena el\u00a0seu tractament: la dificultat dels medicaments existents per superar la barrera\u00a0hematoencef\u00e0lica, la protecci\u00f3 natural del cervell.<\/span>\u00a0<\/span><\/p>\n

En aquest context, el programa\u00a0<\/span><\/span>IBEC\u00a0<\/span>Faster<\/span>\u00a0<\/span>Future<\/span><\/span><\/a>\u00a0ha fet possible que durant els dos \u00faltims anys, i gr\u00e0cies als 28.957,20\u20ac recaptats amb les donacions, sota la direcci\u00f3 de la\u00a0<\/span><\/span>Professora d’Investigaci\u00f3 ICREA a\u00a0<\/span>l\u2019<\/span>IBEC S\u00edlvia Mur<\/span>o<\/span><\/span><\/a>\u00a0s’hagi estudiat l’\u00fas d’anticossos com a base d’un producte terap\u00e8utic que “obri el pany de la barrera\u00a0<\/span>hematoencef\u00e0lica<\/span>” i possibiliti el tractament de<\/span>l\u00a0<\/span>Parkinson<\/span>.<\/span><\/span>\u00a0<\/span><\/strong><\/p>\n

\"\"
Profesora Silvia Muro<\/figcaption><\/figure>\n

En concret, l’equip de la Professora Muro ha investigat la possibilitat de desenvolupar un antic\u00f2s universal que pugui unir-se a<\/span>l\u00a0<\/span>receptor endotelial d’inter\u00e8s, tant en animals de laboratori necessaris per a l’aven\u00e7 cl\u00ednic com en humans.<\/span> <\/span><\/span>\u00a0<\/span><\/p>\n

Durant el projecte, i entre altres objectius, els investigadors van identificar la regi\u00f3 m\u00e9s id\u00f2nia del receptor d’inter\u00e8s que servir\u00e0 com a diana per al desenvolupament de l’antic\u00f2s universal, i van aconseguir produir nous models cel\u00b7lulars que expressen el receptor endotelial d’inter\u00e8s d’hum\u00e0, ratol\u00ed, porc, gos i simi. Aquests models s\u00f3n imprescindibles per a la identificaci\u00f3 i caracteritzaci\u00f3 d’anticossos “universals” i serviran d’ajuda en el camp de la biologia i la ter\u00e0pia dirigida al receptor endotelial d’inter\u00e8s.<\/p>\n

Tots els detalls de la investigaci\u00f3 es poden consultar a l’<\/span><\/span>informe<\/span><\/span><\/a>\u00a0publicat a la p\u00e0gina\u00a0<\/span>d<\/span>\u2019<\/span><\/span>ibecbarcelona.org<\/span><\/span><\/a>. Anteriorment, i amb l’objectiu d’anar donant a con\u00e8ixer els objectius del projecte, la Professora Mur<\/span>o<\/span>\u00a0va realitzar una\u00a0<\/span><\/span>xerrada divulgativa<\/span><\/span><\/a>\u00a0amb l’<\/span><\/span>Associaci\u00f3 Catalana de\u00a0<\/span>Parkinson<\/span><\/span><\/a>. Durant\u00a0<\/span>aquesta<\/span>, no solament es va poder posar al dia als pacients de\u00a0<\/span>Parkinson<\/span>\u00a0dels aven\u00e7os cient\u00edfics que s’estaven desenvolupant en aquest camp, sin\u00f3 que tamb\u00e9 va oferir als investigadors i a l’IBEC l’oportunitat de con\u00e8ixer, de primera m\u00e0, les inquietuds de pacients de\u00a0<\/span>Parkinson<\/span>\u00a0i de les seves fam\u00edlies.<\/span><\/span>\u00a0<\/span><\/strong><\/p>\n

Les aportacions dels donants tamb\u00e9 van fer possible que la l\u00ednia d’investigaci\u00f3 de la Professora Mur<\/span>o<\/span>\u00a0aconsegu\u00eds finan\u00e7ament a trav\u00e9s de fons competitius p\u00fablics per a la investigaci\u00f3. Gr\u00e0cies a tot aix\u00f2, els investigadors seguiran treballant per intentar donar resposta a uns dels majors reptes de la medicina moderna: desenvolupar “vehicles” que\u00a0<\/span>facin possible el transport de medicaments a trav\u00e9s de la barrera\u00a0<\/span>hematoencef\u00e0lica<\/span>\u00a0i que ajudin a lluitar contra el\u00a0<\/span>Parkinson<\/span>.<\/span><\/span>\u00a0<\/span><\/p>\n

Aquestes generoses donacions han fet possible l’inici, i els passos m\u00e9s crucials, d’aquest nou projecte centrat\u00a0a\u00a0habilitar el pas de f\u00e0rmacs\u00a0al\u00a0cervell per al tractament del\u00a0Parkinson<\/span>\u00a0i altres malalties neurodegeneratives, causa amb la qual seguirem altament compromesos.<\/strong><\/p>\n

 <\/p>\n

Professora ICREA Silvia Muro, IBEC<\/strong><\/p>\n<\/blockquote>\n

 <\/p>\n

L’equip cient\u00edfic i administratiu de l’IBEC agraeix la implicaci\u00f3 i comprom\u00eds de tots els donants, tant individuals com institucionals, entre els quals es troben\u00a0<\/span><\/span>C<\/span>ementos<\/span>\u00a0Molins<\/span><\/span><\/a>,\u00a0<\/span><\/span>Zeiss<\/span><\/span><\/a>,\u00a0<\/span><\/span>Izasa<\/span>\u00a0<\/span>Scientific<\/span><\/span><\/a>,\u00a0<\/span><\/span>Eppendorf<\/span><\/span><\/a>,\u00a0<\/span><\/span>Seidor<\/span><\/span><\/a>,\u00a0<\/span><\/span>Barcelona Global<\/span><\/span><\/a>\u00a0i\u00a0<\/span><\/span>Proaudit<\/span><\/span><\/a>, que han fet possible aquest projecte<\/span><\/span>. <\/span><\/span><\/em>\u00a0<\/span><\/strong><\/p>\n

Per a m\u00e9s informaci\u00f3, i contribucions a altres projectes en marxa, es pot visitar la p\u00e0gina “<\/span><\/span>IBEC\u00a0<\/span>Faster<\/span>\u00a0<\/span>Future<\/span><\/span><\/a>“.<\/span><\/span>\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

El programa IBEC Faster Future ha fet possible, durant els dos \u00faltims anys, i gr\u00e0cies a les aportacions dels donants, l’estudi d’anticossos com a base d’un producte terap\u00e8utic per al tractament del Parkinson. Els investigadors presenten ara els aven\u00e7os cient\u00edfics, i seguiran treballant per intentar donar resposta a uns dels majors reptes de la medicina moderna: les patologies neurodegeneratives com el Parkinson.<\/h3>\n","protected":false},"author":4,"featured_media":87488,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[98],"tags":[1125],"post_formats":[],"class_list":["post-87504","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-institucionals","tag-silvia-muro-ca"],"yoast_head":"\nLa campanya Faster Future contra el Parkinson culmina amb nous aven\u00e7os cient\u00edfics - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/la-campanya-faster-future-contra-el-parkinson-culmina-amb-nous-avencos-cientifics\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"La campanya Faster Future contra el Parkinson culmina amb nous aven\u00e7os cient\u00edfics - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"El programa IBEC Faster Future ha fet possible, durant els dos \u00faltims anys, i gr\u00e0cies a les aportacions dels donants, l'estudi d'anticossos com a base d'un producte terap\u00e8utic per al tractament del Parkinson. 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