{"id":92647,"date":"2022-01-14T11:59:58","date_gmt":"2022-01-14T10:59:58","guid":{"rendered":"https:\/\/testweb.ibecbarcelona.eu\/?p=92647"},"modified":"2022-03-22T11:08:24","modified_gmt":"2022-03-22T10:08:24","slug":"ultims-avencos-de-la-nanomedicina-europea-contra-la-malaria-explicats-en-un-nou-video","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/ultims-avencos-de-la-nanomedicina-europea-contra-la-malaria-explicats-en-un-nou-video\/","title":{"rendered":"\u00daltims aven\u00e7os de la nanomedicina europea contra la mal\u00e0ria explicats en un nou v\u00eddeo"},"content":{"rendered":"\n<h4 class=\"wp-block-heading\">La mal\u00e0ria mata m\u00e9s de 500.000 persones cada any. En els darrers tres anys, els investigadors del Projecte NANOpheles van treballar en el desenvolupament de nanovectors dirigits als par\u00e0sits Plasmodium dins del mosquit vector. Xavier Fern\u00e0ndez-Busquets, coordinador del projecte finan\u00e7at per la UE, explica els aven\u00e7os en un nou v\u00eddeo.<\/h4>\n\n\n<p><img decoding=\"async\" class=\"alignleft wp-image-89951 lazyload\" data-src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/close-up-mosquito-sucking-blood-from-human-arm_peq_-300x170.jpg\" alt=\"\" width=\"451\" height=\"255\" data-srcset=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/close-up-mosquito-sucking-blood-from-human-arm_peq_-300x170.jpg 300w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/close-up-mosquito-sucking-blood-from-human-arm_peq_-1024x579.jpg 1024w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/close-up-mosquito-sucking-blood-from-human-arm_peq_-768x434.jpg 768w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/close-up-mosquito-sucking-blood-from-human-arm_peq_-1536x868.jpg 1536w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/close-up-mosquito-sucking-blood-from-human-arm_peq_-2048x1157.jpg 2048w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/close-up-mosquito-sucking-blood-from-human-arm_peq_-230x130.jpg 230w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/close-up-mosquito-sucking-blood-from-human-arm_peq_-150x85.jpg 150w\" data-sizes=\"(max-width: 451px) 100vw, 451px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 451px; --smush-placeholder-aspect-ratio: 451\/255;\" \/><\/p>\n<p><span class=\"TextRun SCXW145233532 BCX8\" lang=\"CA-ES\" xml:lang=\"CA-ES\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW145233532 BCX8\">Mentre que els enfocaments\u00a0<\/span><span class=\"NormalTextRun SpellingErrorV2 SCXW145233532 BCX8 DefaultHighlightTransition\">nanom\u00e8dics<\/span><span class=\"NormalTextRun SCXW145233532 BCX8\">\u00a0per curar malalties prevalen als pa\u00efsos desenvolupats, hi ha una sorprenent falta de\u00a0<\/span><span class=\"NormalTextRun SpellingErrorV2 SCXW145233532 BCX8\">nanomedicines<\/span><span class=\"NormalTextRun SCXW145233532 BCX8\">\u00a0enfocades a tractar les malalties infeccioses, principal causa de mort a les \u00e0rees m\u00e9s pobres del planeta, entre les quals destaca la mal\u00e0ria, tamb\u00e9 coneguda com a paludisme. El 2020, les morts per paludisme van augmentar un 12% en comparaci\u00f3 del 2019, arribant a un nombre estimat de casos de 627.000.<\/span><\/span><span class=\"EOP SCXW145233532 BCX8\" data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:360}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">En els darrers tres anys, la unitat mixta de\u202fNanomal\u00e0ria\u202fde l&#8217;Institut de Bioenginyeria de Catalunya (IBEC) i Institut de Salut Global de Barcelona (ISGlobal), dirigida per\u202fFern\u00e0ndez-Busquets, juntament amb socis internacionals, ha estat explorant solucions innovadores que contribueixin a\u202ferradicar\u202faquesta malaltia. En el marc del projecte finan\u00e7at amb fons europeus, el consorci va treballar en el desenvolupament\u00a0de\u202fnanovectors\u202fper a la distribuci\u00f3 selectiva d&#8217;agents que bloquegen el desenvolupament de par\u00e0sits\u202f<\/span><i><span data-contrast=\"none\">Plasmodium<\/span><\/i><span data-contrast=\"none\">\u202fdins de mosquits\u202f<\/span><i><span data-contrast=\"none\">Anopheles<\/span><\/i><span data-contrast=\"none\">, vector de la malaltia.<\/span><\/p>\n<p><span data-contrast=\"none\">NANOpheles\u202funeix grups de recerca l\u00edders en s\u00edntesi de nanopart\u00edcules, administraci\u00f3 dirigida de f\u00e0rmacs a c\u00e8l\u00b7lules infectades per\u202f<\/span><i><span data-contrast=\"none\">Plasmodium<\/span><\/i><span data-contrast=\"none\">, biologia cel\u00b7lular i molecular del patogen, models de ratol\u00ed i mosquits vectors de la mal\u00e0ria, i els aspectes cl\u00ednics de la malaltia.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:360}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Els resultats del projecte han proporcionat (i) diversos\u202fnanotransportadors\u202fdirigits espec\u00edficament a les etapes de desenvolupament de\u202fPlasmodium\u202fal mosquit vector i l&#8217;epiteli de l&#8217;intest\u00ed mitj\u00e0 de l&#8217;insecte que el par\u00e0sit ha de travessar per una ruta\u202ftranscel\u00b7lular, cosa que representa una c\u00e8l\u00b7lula diana ideal per als antipal\u00fadics, (ii) un nou f\u00e0rmac antipal\u00fadic pertanyent a una nova fam\u00edlia qu\u00edmica que actua a trav\u00e9s d&#8217;un mecanisme no descrit anteriorment, i que tamb\u00e9 \u00e9s actiu sobre el patogen als estadis dins del mosquit, i (iii) un nou\u202fnanotransportador\u202fpolim\u00e8ric capa\u00e7 de potenciar fins a un mili\u00f3 de vegades la solubilitat en medi aqu\u00f3s de f\u00e0rmacs\u00a0lipof\u00edlics, d&#8217;aplicabilitat a una \u00e0mplia gamma de malalties incloent c\u00e0ncer, malalties metab\u00f2liques i trastorns neurol\u00f2gics. Els resultats\u202fd&#8217;aquest\u202fprojecte han donat lloc a la presentaci\u00f3 de dues sol\u00b7licituds de patent\u202fi a\u202fdiverses publicacions cient\u00edfiques.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:360}\">\u00a0<\/span><\/p>\n<p><span class=\"TextRun Highlight SCXW222362107 BCX8\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW222362107 BCX8\">Descobreix m\u00e9s en aquest v\u00eddeo:<\/span><\/span><span class=\"EOP CommentStart SCXW222362107 BCX8\" data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:360}\">\u00a0<\/span><\/p>\n<p><iframe title=\"NANOpheles Project\" width=\"1200\" height=\"675\" data-src=\"https:\/\/www.youtube.com\/embed\/xN8w33T7-ZM?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" data-load-mode=\"1\"><\/iframe><\/p>\n<p><img decoding=\"async\" class=\"alignnone wp-image-89966 lazyload\" data-src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/Logo-EU-horizontal-300x47.png\" alt=\"\" width=\"396\" height=\"62\" data-srcset=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/Logo-EU-horizontal-300x47.png 300w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/Logo-EU-horizontal-1024x160.png 1024w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/Logo-EU-horizontal-768x120.png 768w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/Logo-EU-horizontal-1536x240.png 1536w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/Logo-EU-horizontal-2048x320.png 2048w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/Logo-EU-horizontal-150x23.png 150w\" data-sizes=\"(max-width: 396px) 100vw, 396px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 396px; --smush-placeholder-aspect-ratio: 396\/62;\" \/> <img decoding=\"async\" class=\"alignnone wp-image-89969 lazyload\" data-src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/Logo-Nanopheles-300x105.png\" alt=\"\" width=\"232\" height=\"81\" data-srcset=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/Logo-Nanopheles-300x105.png 300w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/Logo-Nanopheles-150x53.png 150w, https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2022\/01\/Logo-Nanopheles.png 675w\" data-sizes=\"(max-width: 232px) 100vw, 232px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 232px; --smush-placeholder-aspect-ratio: 232\/81;\" \/><\/p>\n<p>\u00a0<\/p>\n<p><em><span class=\"TextRun SCXW163700823 BCX8\" lang=\"ES-ES\" xml:lang=\"ES-ES\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW163700823 BCX8\">Financiaci\u00f3n\u00a0<\/span><span class=\"NormalTextRun SpellingErrorV2 SCXW163700823 BCX8\">NANOpheles<\/span><span class=\"NormalTextRun SCXW163700823 BCX8\">:\u00a0<\/span><span class=\"NormalTextRun SCXW163700823 BCX8\">ERA-NET\u00a0<\/span><span class=\"NormalTextRun SpellingErrorV2 SCXW163700823 BCX8\">Cofund<\/span><span class=\"NormalTextRun SCXW163700823 BCX8\">\u00a0EURONANOMED (<\/span><span class=\"NormalTextRun SCXW163700823 BCX8\">n\u00famero de proyecto<\/span><span class=\"NormalTextRun SCXW163700823 BCX8\">\u00a02017-178)<\/span><\/span><span class=\"EOP SCXW163700823 BCX8\" data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:360}\">\u00a0<\/span><\/em><\/p>","protected":false},"excerpt":{"rendered":"<h3> La mal\u00e0ria mata m\u00e9s de 500.000 persones cada any. En els darrers tres anys, els investigadors del Projecte NANOpheles van treballar en el desenvolupament de nanovectors dirigits als par\u00e0sits Plasmodium dins del mosquit vector. Xavier Fern\u00e0ndez-Busquets, coordinador del projecte finan\u00e7at per la UE, explica els aven\u00e7os en un nou v\u00eddeo. <\/h3>\n","protected":false},"author":4,"featured_media":89950,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[98],"tags":[1112],"post_formats":[],"class_list":["post-92647","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-institucionals","tag-xavier-fernandez-busquets-ca"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u00daltims aven\u00e7os de la nanomedicina europea contra la mal\u00e0ria explicats en un nou v\u00eddeo - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/ultims-avencos-de-la-nanomedicina-europea-contra-la-malaria-explicats-en-un-nou-video\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u00daltims aven\u00e7os de la nanomedicina europea contra la mal\u00e0ria explicats en un nou v\u00eddeo - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"La mal\u00e0ria mata m\u00e9s de 500.000 persones cada any. 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