{"id":92687,"date":"2022-01-19T09:00:00","date_gmt":"2022-01-19T08:00:00","guid":{"rendered":"https:\/\/testweb.ibecbarcelona.eu\/?p=92687"},"modified":"2022-03-22T12:17:48","modified_gmt":"2022-03-22T11:17:48","slug":"tres-investigadors-de-libec-guanyen-beques-de-la-fundacio-la-caixa-per-a-joves-liders-cientifics","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/tres-investigadors-de-libec-guanyen-beques-de-la-fundacio-la-caixa-per-a-joves-liders-cientifics\/","title":{"rendered":"Tres investigadors de l’IBEC guanyen beques de la Fundaci\u00f3 \u201cLa Caixa\u201d per a joves l\u00edders cient\u00edfics"},"content":{"rendered":"\n

Veronika Magdanz, del Grup de Nano Dispositius Intel\u00b7ligents liderat per Samuel S\u00e1nchez, aix\u00ed com Iris Batalha i Mohit Kumar del grup \u201cMolecular Bionics\u201d liderat per Giuseppe Battaglia, han estat seleccionats entre m\u00e9s de 700 candidats per a una beca dins de la convocat\u00f2ria competitiva de postdoctorat per a joves l\u00edders cient\u00edfics de la Fundaci\u00f3 \u201cLa Caixa\u201d. Gr\u00e0cies a aquestes beques, els investigadors treballaran en innovadors sistemes micro i nano que busquen contribuir a una millor comprensi\u00f3, ia solucions, a problemes de salut.<\/h4>\n\n\n\n
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Guanyadors de la beca Fundaci\u00f3<\/span> “La Caixa”<\/span><\/span><\/figcaption><\/figure><\/div>\n\n\n\n

La Fundaci\u00f3 \u201cLa Caixa\u201d ha donat a con\u00e8ixer els guanyadors d’una beca dins de la convocat\u00f2ria competitiva de\u00a0postdoctorat per a joves l\u00edders cient\u00edfics<\/a>.\u00a0<\/p>\n\n\n\n

A aquesta convocat\u00f2ria s’hi han presentat m\u00e9s de 700 persones per optar a una de les beques. Dels 45 investigadors seleccionats, 3 pertanyen a l’Institut de Bioenginyeria de Catalunya (IBEC). Veronika Magdanz, del\u00a0Grup Nano Dispositius Biol\u00f2gics Intel\u00b7ligents<\/a>, liderat per Samuel S\u00e1nchez, aix\u00ed com Iris Batalha i Mohit Kumar del grup \u201cMolecular Bionics<\/a>\u201d liderat per Giuseppe Battaglia, treballaran els pr\u00f3xims\u00a0tres anys en la investigaci\u00f3 de sistemes micro i nano que puguin contribuir a solucions a problemes de salut.\u00a0<\/p>\n\n\n\n

Veronika\u00a0Magdanz:\u00a0microrobots\u00a0inspirats en la natura per a aplicacions biom\u00e8diques<\/strong>\u00a0<\/strong><\/h3>\n\n\n\n

<\/p>\n\n\n\n

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Nascuda a\u00a0Rathenow\u00a0(Alemanya) el 1985, va estudiar biotecnologia a la TU\u00a0Braunschweig\u00a0entre 2004 i 2010 i enginyeria qu\u00edmica a la Universitat de\u00a0Waterloo\u00a0(Canad\u00e0) entre 2007 i 2008 com a estudiant d’intercanvi ISAP. Es va doctorar en biologia el 2016 a la TU Dresden despr\u00e9s de fer un treball pioner sobre\u00a0microrobots\u00a0bioh\u00edbrids\u00a0a l’Institut de\u00a0Nanoci\u00e8ncies\u00a0Integratives de l’Institut Leibniz de Recerca de l’Estat S\u00f2lid i els Materials de Dresden (IFW). Del 2017 al 2020, va dur a terme estudis metab\u00f2lics i cin\u00e8tics en espermatozoides de diverses esp\u00e8cies com a investigaci\u00f3 de\u00a0postdoctorat\u00a0de tema obert a la c\u00e0tedra de zoologia aplicada de la TU Dresden, a m\u00e9s de continuar la seva investigaci\u00f3 sobre els\u00a0microrobots\u00a0h\u00edbrids d’esperma. El 2020, va rebre una beca\u00a0Feodor-Lynen\u00a0de la Fundaci\u00f3 Alexander von\u00a0Humboldt\u00a0per unir-se al grup de Nano\u00a0Biodispositius\u00a0intel\u00b7ligents de l’IBEC.\u00a0<\/p>\n<\/div><\/div>\n\n\n\n

M’inspirar\u00e9 en la natura per crear\u00a0microrobots\u00a0que s’impulsin gr\u00e0cies a camps magn\u00e8tics. \u00a0<\/strong><\/p>Veronika\u00a0Magdanz\u00a0<\/em><\/cite><\/blockquote>\n\n\n\n

La creaci\u00f3 i el control de\u00a0microrobots\u00a0intel\u00b7ligents i aut\u00f2noms \u00e9s un dels fascinants objectius de la seva investigaci\u00f3 actual. Sovint aquest camp de la\u00a0microrob\u00f2tica\u00a0s’inspira en la natura. En el projecte Junior\u00a0Leader\u00a0de la Fundaci\u00f3 \u201dla Caixa\u201d,\u00a0Veronika\u00a0Magdanz\u00a0investigar\u00e0 el comportament cooperatiu dels espermatozoides, que els ajuda a nedar de manera m\u00e9s r\u00e0pida i efica\u00e7 formant grups que en fer-ho com a c\u00e8l\u00b7lules individuals. A m\u00e9s, aplicar\u00e0 aquests coneixements al disseny de nedadors flagel\u00b7lats que siguin flexibles i multifuncionals i s’impulsin mitjan\u00e7ant l’efecte de camps magn\u00e8tics oscil\u00b7lants. Per \u00faltim, explorar\u00e0\u00a0les aplicacions biom\u00e8diques d’aquests robots flexibles per a l’administraci\u00f3 de c\u00e8l\u00b7lules, f\u00e0rmacs i teixits. Aquest camp de recerca es nodreix de coneixements d\u2019enginyeria, aix\u00ed com de biologia, ci\u00e8ncia dels materials, qu\u00edmica i biof\u00edsica.\u00a0<\/p>\n\n\n\n

Mohit\u00a0Kumar: materials similars a sistemes vius per generar\u00a0nanof\u00e0rmacs\u00a0<\/strong><\/strong><\/h3>\n\n\n\n
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Va n\u00e9ixer a\u202fMunger\u202f(\u00cdndia) el 1986 i va realitzar un m\u00e0ster en qu\u00edmica a l’\u00cdndia. Va rebre una prestigiosa beca de doctorat del govern indi. Va\u202fdur a terme\u202fel doctorat amb el\u202fProf.\u202fSubi\u202fGeorge al Centre de Recerca Cient\u00edfica Avan\u00e7ada\u202fJawaharlal\u202fNehru\u202fi va\u00a0rebre el premi a la millor tesi doctoral (equivalent a\u00a0cum\u00a0laude) el 2014. El 2015, es va traslladar a la City\u202fUniversity\u202fde Nova York (Estats Units) per\u202fdur a terme\u202fun\u202fpostdoctorat\u202famb el\u202fProf.\u202fRein\u202fUlijn. Tamb\u00e9 va rebre una beca de recerca de\u202fla US-Israel\u202fBinational\u202fScience\u202fFoundation. \u00c9s autor de 22 publicacions i posseeix una patent nord-americana (>1000 cites, \u00edndex h de 14). \u00c9s autor principal de diversos articles publicats en revistes com\u202fNature\u202fChemistry<\/em>\u202fi\u202fNature\u202fCommunications<\/em>,\u202fincloent-hi\u202ftres articles com a autor per a correspond\u00e8ncia. Ha impartit confer\u00e8ncies a congressos internacionals i ha estat mentor d’alumnes de m\u00e0ster i doctorat. En resum, \u00e9s un qu\u00edmic consumat i amb experi\u00e8ncia internacional que ha creat un n\u00ednxol cient\u00edfic per abordar reptes socials en mat\u00e8ria de salut i energia.\u00a0<\/p>\n<\/div><\/div>\n\n\n\n

Dissenyar\u00e9 un material org\u00e0nic capa\u00e7 d’adaptar-se que ens ajudi a administrar f\u00e0rmacs de forma m\u00e9s eficient.<\/p>

<\/p>Mohit\u00a0Kumar<\/em><\/cite><\/blockquote>\n\n\n\n

Els sistemes vius s\u00f3n molt din\u00e0mics i les seves estructures\u00a0autoacoblades\u00a0es formen i es descomponen constantment a trav\u00e9s del consum\u202fd’energia\u202fqu\u00edmica. Aix\u00f2\u00a0d\u00f3na\u00a0lloc a funcions \u00faniques com\u202fl’adaptaci\u00f3\u202fi la motilitat, entre altres. El funcionament biol\u00f2gic \u00e9s clarament diferent del de la majoria dels materials sint\u00e8tics, que no tenen la capacitat de canviar per adaptar-s’hi. Aix\u00f2 crea un desajust entre els sistemes vius i els materials sint\u00e8tics, per la qual cosa resulta dif\u00edcil desenvolupar\u202fbiointerf\u00edcies\u202fsint\u00e8tiques per a la\u00a0nanomedicina. Aquesta proposta incorporar\u00e0 els principis de funcionament de la natura al disseny de materials de fabricaci\u00f3 humana per adquirir funcions d’adaptabilitat i\u00a0reconfiguraci\u00f3. En el seu projecte, el Dr.\u202fKumar\u202fdissenyar\u00e0 un material org\u00e0nic capa\u00e7 d’adaptar-se mitjan\u00e7ant un proc\u00e9s continu de formaci\u00f3\/degradaci\u00f3 i el consum d’energia qu\u00edmica. D’aquesta manera, es crearan 1) ves\u00edcules lip\u00eddiques com a interf\u00edcie cel\u00b7lular adaptable per a l’administraci\u00f3 dirigida de f\u00e0rmacs a les c\u00e8l\u00b7lules canceroses, i 2) un dispositiu reconfigurable per a la detecci\u00f3 i el diagn\u00f2stic\u202fmultianalit\u202fsota demanda. Aix\u00ed doncs,\u202ffar\u00e9\u202fun material amb funcions similars a les de la vida per a la propera generaci\u00f3 de\u202fnanof\u00e0rmacs.\u00a0<\/p>\n\n\n\n

Iris\u00a0Batalha:\u00a0Nanobi\u00f2tics\u00a0multivalents i\u00a0superselectius\u00a0contra la tuberculosi\u00a0<\/strong><\/strong><\/h3>\n\n\n\n
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Va n\u00e9ixer a\u00a0\u00c9vora\u00a0(Portugal) el 1984. \u00c9s graduada en qu\u00edmica aplicada i t\u00e9 un m\u00e0ster en biotecnologia per la Facultat de Ci\u00e8ncies i Tecnologia de la Universitat Nova de Lisboa (FCT\u202fNOVA), aix\u00ed com un doctorat en sistemes de bioenginyeria pel Programa MIT -Portugal. Del 2014 al 2017, va ser investigadora\u00a0postdoctoral\u00a0al Departament d’Enginyeria Qu\u00edmica i Biotecnologia de la Universitat de\u00a0Cambridge\u202fi a\u202fl’empresa\u00a0biofarmac\u00e8utica\u202fMedImmune\/Astrazeneca. Del 2017 al 2020, va ser investigadora associada en un projecte de recerca conjunt entre el Centre de\u00a0Nanoci\u00e8ncia\u00a0del Departament d’Enginyeria i la Unitat d’Immunitat Molecular del Departament de Medicina de la Universitat de\u00a0Cambridge. Actualment, \u00e9s directora d’un curs de\u202fnanoter\u00e0pies\u202fa l’Institut d’Educaci\u00f3 Cont\u00ednua de la Universitat de\u00a0Cambridge, consultora s\u00e8nior freelance en estrat\u00e8gies d’innovaci\u00f3 a\u202fInspiralia\u202f(Espanya i els Estats Units), cofundadora, directora i redactora en cap de l’organitzaci\u00f3 sense \u00e0nim de lucre\u202fWomen\u202fAhead\u202fof\u202fTheir\u202fTime\u202f(WATT), i membre del\u202fPeterhouse\u202fCollege,\u00a0Cambridge.\u00a0<\/p>\n<\/div><\/div>\n\n\n\n

La meva ambici\u00f3 \u00e9s descobrir nous mecanismes moleculars d’infecci\u00f3 bacteriana i el desenvolupament de resist\u00e8ncia als medicaments, i crear nanopart\u00edcules terap\u00e8utiques\u00a0bioinspirades\u00a0i dirigides espec\u00edficament a les c\u00e8l\u00b7lules humanes infectade.<\/strong><\/p>

<\/p>Iris\u00a0Batalha<\/em><\/cite><\/blockquote>\n\n\n\n

Cada minut moren tres persones per infecci\u00f3 de M. tuberculosis<\/em>. Els tractaments actuals requereixen l’administraci\u00f3 d’altes concentracions d’un c\u00f2ctel d’antibi\u00f2tics, i nom\u00e9s una petita quantitat arriba al lloc de destinaci\u00f3 al cos. Aix\u00f2 provoca una s\u00e8rie d’efectes adversos als pacients, que deixen de prendre la medicaci\u00f3 a meitat del tractament i, en \u00faltima inst\u00e0ncia, condueix al desenvolupament de resist\u00e8ncies als antibi\u00f2tics. La meva feina se centra en el desenvolupament de\u00a0nanof\u00e0rmacs\u00a0constitu\u00efts per conjugats d’antibi\u00f2tics i pol\u00edmers per a l’administraci\u00f3 dirigida de f\u00e0rmacs espec\u00edficament als llocs d’infecci\u00f3. El meu objectiu \u00e9s actuar directament a les c\u00e8l\u00b7lules humanes infectades mitjan\u00e7ant el disseny de lligands pept\u00eddics a trav\u00e9s de la t\u00e8cnica de presentaci\u00f3 en\u00a0fags\u00a0(Phage\u00a0display<\/em>). Aquests lligands reconeixen i s’uneixen selectivament a receptors de la superf\u00edcie de les \u201cc\u00e8l\u00b7lules hoste\u201d que presenten notables alteracions durant la infecci\u00f3. En concret, pretenc actuar sobre el sistema de presentaci\u00f3 d’ant\u00edgens relacionat amb el complex major d’histocompatibilitat de classe I (MR1 o MHC1-related), el qual est\u00e0\u00a0altament conservat entre esp\u00e8cies. L’MR1 resideix a l’interior de la c\u00e8l\u00b7lula humana hoste i \u00e9s transportat a la superf\u00edcie quan s’uneix a metab\u00f2lits bacterians que es troben dins de la c\u00e8l\u00b7lula humana, de manera que funciona com un interruptor molecular i realitza un mostreig de l’entorn intracel\u00b7lular de l’hoste infectat.\u00a0<\/p>\n\n\n\n

\n\n\n\n

Sobre el programa de\u00a0postdoctorat\u00a0Junior\u00a0Leader<\/strong>\u00a0<\/strong><\/p>\n\n\n\n

Cofinan\u00e7at per la Comissi\u00f3 Europea a trav\u00e9s de l’Acci\u00f3\u202fMarie\u202fSk\u0142odowska-Curie\u202fCOFUND\u202fen el marc d’Horitz\u00f3 2020, aquest programa est\u00e0 destinat a la contractaci\u00f3 d’investigadors excel\u00b7lents de qualsevol nacionalitat que vulguin continuar la seva carrera investigadora en territori espanyol o portugu\u00e8s a les \u00e0rees de les ci\u00e8ncies de la salut i de la vida, la tecnologia, la f\u00edsica,\u202fl’enginyeria\u202fi les matem\u00e0tiques.
A aquesta convocat\u00f2ria s’hi han presentat m\u00e9s de 700 persones per optar a una de les beques. Dels 45 investigadors seleccionats, 20 s\u00f3n espanyols (de 14 prov\u00edncies diferents) i 25 estrangers (procedents de 14 pa\u00efsos).
Aquestes beques de\u202fpostdoctorat, que tenen una durada de\u202ftres\u202fanys i una dotaci\u00f3 de 305.100 euros per beca, inclouen un programa de formaci\u00f3 complement\u00e0ria la finalitat del qual \u00e9s consolidar les habilitats de recerca i fomentar la carrera cient\u00edfica independent com a opci\u00f3 de futur professional, tractant temes com el lideratge, la resoluci\u00f3 de conflictes o la comunicaci\u00f3.<\/p>\n","protected":false},"excerpt":{"rendered":"

Veronika Magdanz, del Grup de Nano Dispositius Intel\u00b7ligents liderat per Samuel S\u00e1nchez, aix\u00ed com Iris Batalha i Mohit Kumar del grup \u201cMolecular Bionics\u201d liderat per Giuseppe Battaglia, han estat seleccionats entre m\u00e9s de 700 candidats per a una beca dins de la convocat\u00f2ria competitiva de postdoctorat per a joves l\u00edders cient\u00edfics de la Fundaci\u00f3 \u201cLa Caixa\u201d. Gr\u00e0cies a aquestes beques, els investigadors treballaran en innovadors sistemes micro i nano que busquen contribuir a una millor comprensi\u00f3, ia solucions, a problemes de salut. <\/h3>\n","protected":false},"author":4,"featured_media":92684,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[98],"tags":[1104,1140],"post_formats":[],"class_list":["post-92687","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-institucionals","tag-giuseppe-battaglia-ca","tag-samuel-sanchez-ca"],"yoast_head":"\nTres investigadors de l'IBEC guanyen beques de la Fundaci\u00f3 \u201cLa Caixa\u201d per a joves l\u00edders cient\u00edfics - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/tres-investigadors-de-libec-guanyen-beques-de-la-fundacio-la-caixa-per-a-joves-liders-cientifics\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tres investigadors de l'IBEC guanyen beques de la Fundaci\u00f3 \u201cLa Caixa\u201d per a joves l\u00edders cient\u00edfics - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Veronika Magdanz, del Grup de Nano Dispositius Intel\u00b7ligents liderat per Samuel S\u00e1nchez, aix\u00ed com Iris Batalha i Mohit Kumar del grup \u201cMolecular Bionics\u201d liderat per Giuseppe Battaglia, han estat seleccionats entre m\u00e9s de 700 candidats per a una beca dins de la convocat\u00f2ria competitiva de postdoctorat per a joves l\u00edders cient\u00edfics de la Fundaci\u00f3 \u201cLa Caixa\u201d. 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