{"id":9869,"date":"2014-11-20T11:16:03","date_gmt":"2014-11-20T11:16:03","guid":{"rendered":"http:\/\/ibecbarcelona.eu\/new\/?p=9869"},"modified":"2015-10-19T15:50:16","modified_gmt":"2015-10-19T15:50:16","slug":"sistema-olfactiu-que-segrega-les-dades-de-lolor-en-el-moment-de-lentrada","status":"publish","type":"post","link":"https:\/\/ibecbarcelona.eu\/ca\/sistema-olfactiu-que-segrega-les-dades-de-lolor-en-el-moment-de-lentrada\/","title":{"rendered":"Sistema olfactiu que segrega les dades de l\u2019olor en el moment de l\u2019entrada"},"content":{"rendered":"<h6 class=\"caption\" style=\"width: 230px; float: left; padding-right: 10px; padding-bottom: 10px;\"><em>Imatge: C\u00e8l\u00b7lules mitrals i c\u00e8l\u00b7lules en plomall \u00a9 Brain Institute and Department of Physiology, University of Utah School of Medicine<\/em><\/h6>\n<p>El grup de Processament de Senyals per a Sistemes Sensorials del IBEC ha descobert la forma en la que identifiquem les olors incl\u00f2s quan les seves concentracions s\u00f3n molt baixes, essencialment el que fem \u00e9s segregat la informaci\u00f3 sobre la identificaci\u00f3 i la concentraci\u00f3 amb la finalitat de ser capa\u00e7os de recon\u00e8ixer una determinada olor.<\/p>\n<p>Per a descobrir aix\u00f2 el que es va fer va ser mirar en la primera etapa del bulb olfactiu \u2013 la capa glomerular, que \u00e9s l\u2019etapa \u201cd\u2019entrada\u201d de les olors \u2013 per a veure si all\u00ed es duia a terme la segregaci\u00f3 de la informaci\u00f3. Juntament amb els seus col\u00b7laboradors a Roma, el grup va construir un model neuronal computacional de l\u2019\u00e0rea basat en les connexions anat\u00f2miques conegudes i el van testar amb dues simulacions experimentals. En el primer experiment, el model va ser exposat a un conjunt de dades d\u2019est\u00edmuls olfactius composades per sis olors diferents, totes a diferents concentracions; el segon va ser un experiment \u2018d\u2019olor mutant\u2019 on una olor pura es converteix en una segona olor diferent a trav\u00e9s de 19 passos graduals.<\/p>\n<p>\u201cHem trobat que la capa glomerular o etapa d\u2019entrada, on la informaci\u00f3 d\u2019identitat i la concentraci\u00f3 de l\u2019olor es barregen quan entra \u00e9s, de fet, l\u2019origen de l\u2019incre\u00efble capacitat del sistema olfactiu per identificar r\u00e0pidament les olors i al mateix tems conservar la informaci\u00f3 sobre la seva concentraci\u00f3\u201d explica Agust\u00ed Guti\u00e9rrez, investigador s\u00e8nior en el grup del IBEC i autor principal de l\u2019article, publicat recentment a PlosOne. \u201cPer a aix\u00f2 s\u2019utilitzen dos tipus diferents de neurones \u2013 les c\u00e8l\u00b7lules mitrals (MC) i les c\u00e8l\u00b7lules externes en plomall (ETs). Les MCs estan a c\u00e0rrec de codificar la identitat de la olor mentre que les Ets se centren en la seva concentraci\u00f3 \u2013 no a causa de les seves difer\u00e8ncies morfol\u00f2giques, sin\u00f3 degut a que els dos tipus de neurones tenen diferents maneres d\u2019actuar amb la xarxa glomerular. Ambd\u00f3s tipus cel\u00b7lulars projecten tota la seva informaci\u00f3 al c\u00f2rtex olfactiu (piriforme) per a la descodificaci\u00f3\u201d.<\/p>\n<p>\u00c9s la primera vegada que s\u2019atribueix a la capa glomerular aquesta important segregaci\u00f3 de la informaci\u00f3 en el processament de la olor, capa que ja era coneguda per realitzar altres tasques com la millora del contrast.<\/p>\n<p>&#8212;<\/p>\n<p><em><strong>Article de refer\u00e8ncia:\u00a0<\/strong><\/em>Davide Polese, Eugenio Martinelli, Santiago Marco, Corrado Di Natale &amp; Agustin Gutierrez (2014). <a href=\"http:\/\/www.plosone.org\/article\/info%3Adoi%2F10.1371%2Fjournal.pone.0109716\" target=\"_blank\"> \u201cUnderstanding Odor Information Segregation in the Olfactory Bulb by Means of Mitral and Tufted Cells\u201d.<\/a> <em>PLoS ONE<\/em> 9(10): e109716<\/p>\n","protected":false},"excerpt":{"rendered":"<h3><img decoding=\"async\" class=\"left lazyload\" data-src=\"https:\/\/ibecbarcelona.eu\/wp-content\/uploads\/2014\/11\/mcs_340.jpg\" border=\"0\" style=\"--smush-placeholder-width: 340px; --smush-placeholder-aspect-ratio: 340\/210;margin-top: 4px;\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" \/>Tots sabem com d\u2019emotius poden ser les olors; nom\u00e9s la subtil olor del cot\u00f3 de sucre o de la plastilina ens pot transportar d\u00e8cades en un moment. <\/h3>\n<p>Per\u00f2, de quina manera el nostre sistema olfactiu \u00e9s capa\u00e7 de recon\u00e8ixer les olors incl\u00f2s en dosis molt baixes?<\/h3>\n","protected":false},"author":4,"featured_media":8543,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[96],"tags":[],"post_formats":[],"class_list":["post-9869","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticies-de-recerca"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Sistema olfactiu que segrega les dades de l\u2019olor en el moment de l\u2019entrada - Institute for Bioengineering of Catalonia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ibecbarcelona.eu\/ca\/sistema-olfactiu-que-segrega-les-dades-de-lolor-en-el-moment-de-lentrada\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sistema olfactiu que segrega les dades de l\u2019olor en el moment de l\u2019entrada - Institute for Bioengineering of Catalonia\" \/>\n<meta property=\"og:description\" content=\"Tots sabem com d\u2019emotius poden ser les olors; nom\u00e9s la subtil olor del cot\u00f3 de sucre o de la plastilina ens pot transportar d\u00e8cades en un moment.  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