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X-WR-CALNAME:Institute for Bioengineering of Catalonia
X-ORIGINAL-URL:https://ibecbarcelona.eu
X-WR-CALDESC:Events for Institute for Bioengineering of Catalonia
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DTSTART:20191027T010000
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DTSTART:20200329T010000
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DTSTART:20201025T010000
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200508T100000
DTEND;TZID=Europe/Madrid:20200508T120000
DTSTAMP:20260426T023135
CREATED:20200421T095637Z
LAST-MODIFIED:20200429T141022Z
UID:73634-1588932000-1588939200@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Elena Martínez
DESCRIPTION:Development of biomimetic models of intestinal tissue: guiding cellular self-organization through biofabrication techniques\n\nElena Martínez \, IBEC \nEpithelial tissues contain three-dimensional (3D) microstructures that guide cell self-organization at the tissue level. In the small intestine\, crypts and finger-like villi microstructures improve its absorbance function\, provides specific microenvironments and compartmentalizes cell types. Despite its physiological relevance\, tissue architecture and multicellular population are neglected in the standard in vitro models\, thus compromising their predictive capabilities. Our efforts in addressing these shortcomings by including key elements to mimic the native tissue in vitro will be discussed in this talk. First\, this will include strategies to promote cell’s self-organization capabilities giving rise to crypt-villus domains on 2D monolayers\, and strategies to engineer cell spatial positioning through micropatterning. Then\, our approach to include the 3D architecture of the tissue will be addressed. In here\, light-based biofabrication techniques to produce 3D villus-like structures will be discussed. Finally\, I will introduce our biofabrication proposal to produce tissue engineered models that include the epithelial and the stromal compartments. Improving the prediction capabilities of cell-based assays is a growing strategy to lead to more efficient drug development processes. As 2D-based systems are showing their limits\, new 3D strategies are gaining acceptance among the scientific community. Our approaches aim to further accelerate this trend by providing feasible strategies to routinely incorporate 3D multicellular structures at the tissue level in cell culture systems. \nThe seminar will take place online at the GoToMeeting Platform \nKnow more about Elena Martínez’s research here
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-elena-martinez/
CATEGORIES:IBEC Seminar
ORGANIZER;CN="IBEC":MAILTO:www.ibecbarcelona.eu
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200515T100000
DTEND;TZID=Europe/Madrid:20200515T120000
DTSTAMP:20260426T023135
CREATED:20200504T102025Z
LAST-MODIFIED:20200508T102953Z
UID:73823-1589536800-1589544000@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Gabriel Gomila
DESCRIPTION:Multiscale approach to bioelectricity\n \nGabriel Gomila \, IBEC \nUnderstanding how electricity is generated and propagated in living systems is key to understand many physiological processes and to develop medical instruments for diagnosis\, monitoring and therapy. \nIn this seminar I will present the multiscale approach to bioelectricity developed in our research group at IBEC\, which covers from multicellular systems to single biomolecules\, with an emphasis on passive electrical properties. Topics will include novel devices for electrophysiological recordings\, novel routes and structures for extracellular electron transfer in bacterial cells\, on-chip impedance flow cytometry\, label-free electrical methods for microbiology and nanoscale electrical mapping of single cells. \nThe seminar will take place online at the GoToMeeting Platform \nKnow more about Gabriel Gomila’s research here
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-gabriel-gomila/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200529T100000
DTEND;TZID=Europe/Madrid:20200529T120000
DTSTAMP:20260426T023135
CREATED:20200504T102344Z
LAST-MODIFIED:20200525T070522Z
UID:73832-1590746400-1590753600@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Giuseppe Battaglia
DESCRIPTION:Bionics at the molecular level: copying Nature to control Nature\n\n\nGiuseppe Battaglia \, IBEC \n\nA very established approach in medicine involves the replacement of organs or other malfunctioning body parts by synthetic versions\, engineered to mimic (or even augment it\, if you allow the sci-fi digression) the original function. Bionics is a very established medical discipline where engineering spouses the life sciences\, creating exquisite combinations. With the help of nanoscience and nanotechnology\, we can now push such an effort down to the molecular level. In our group\, we fabricate synthetic surrogates of trafficking vesicles\, viruses and\, one day perhaps\, even a whole cell. Such molecular bionic units offer more efficient solutions to deliver drugs\, to probe life at the nanoscale\, and to act as a model to understand biological complexity. \n\n\nOur efforts are intrinsically multidisciplinary\, and we mix chemistry\, physics and biology in all we do. We typically start studying biological complexity\, with a strong focus on transport\, trafficking and multivalent interactions (Physical Biology). To help this\, we develop new tools to look at biological systems in four dimensions capturing life’s spatiotemporal patterns (Microscopy). We thus apply a constructionist approach where we mimic biological complexity in the form of design principles such as compartmentalisation\, multivalency and taxis\, to produce functional units from simple building blocks and their interactions (Molecular Engineering).​ Finally\, we apply the resulting constructs to tackle disorders such as cancer\, neurodegeneration\, inflammation\, and infections (Nanomedicine). \n\n\nToday\, I start introducing our research activities giving a few examples of each segment\, to eventually focus my seminar on one of the latest and most exciting developments\, our understanding of multivalent interaction and how these control crucial biological processes\, such as cellular selectivity and trafficking. \n\nThe seminar will take place online at the GoToMeeting Platform \nKnow more about Giuseppe Battaglia’s research here
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-giuseppe-battaglia/
CATEGORIES:IBEC Seminar
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