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DTSTART;TZID=Europe/Madrid:20210709T100000
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CREATED:20210628T090521Z
LAST-MODIFIED:20210628T105718Z
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SUMMARY:Online IBEC Seminar: Xavier Fernàndez-Busquets
DESCRIPTION:Nanomalaria group: 20 years at IBEC\nXavier Fernàndez-Busques\, group leader of the Nanomalaria group at IBEC \nWe will start by briefly looking at the origins of our group back in 2001 as part of IBEC’s embryo\, the Research Center for Bioelectronics and Nanobioscience. Our current activities integrate two decades of cumulative research oriented to the development of targeted nanocarriers for parasitic diseases with focus on malaria but currently expanding to leishmaniasis. \nBecause eventual antimalarial nanomedicines need to be deployed in low per capita income regions\, their final components must take into account this particular economic landscape. Liposomes and polymeric nanocarriers offer advantages and suffer from limitations depending on the severity of the disease in each particular clinical case. Entering erythrocytes\, the host cell of Plasmodium in the blood circulation\, is a challenge in itself due to their lack of endocytic processes. Antibodies\, polysaccharides like heparin\, synthetic polymers and DNA aptamers have been used to target and eventually penetrate red blood cells. \nFinally\, we have recently launched an effort to discover new antimalarial drugs that should constitute the third and final element in the design of targeted nanocarriers for malaria. The know-how acquired in the development of nanocapsules\, targeting elements and drugs has the capacity of being exported to other infectious diseases. Because\, no matter how cost-efficient you can make a nanomedicine\, clinical trials will significantly increase its cost\, we are exploring a radical alternative: designing nanocarriers to target the parasites in their arthropod vectors. \nMore information about Xavier’s research here \nThis seminar will be held using the TEAMS app \n 
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-xavier-fernandez-busquets/
CATEGORIES:IBEC Seminar
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DTSTART;TZID=Europe/Madrid:20210716T100000
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CREATED:20210628T090824Z
LAST-MODIFIED:20210628T105106Z
UID:85642-1626429600-1626436800@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Pau Gorostiza
DESCRIPTION:Electrochemically Gated Charge Transport in Redox Proteins and Photosynthetic Complexes\n\nPau Gorostiza\, group leader of the Nanoprobes and nanoswitches group at IBEC \nInterprotein electron transport is an essential process in cell respiration and photosynthesis. It takes place between redox proteins and complexes\, and it displays an outstanding efficiency and environmental adaptability. Although the biochemistry of electron transport processes is well characterized\, nanoscale experimental methods are needed to understand electronic pathways in these redox protein structures\, both for fundamental and for technological purposes. Electrochemical scanning tunneling microscopy (ECSTM) is an excellent tool to study electronic materials and redox molecules including proteins. It offers single molecule resolution and allows working in aqueous solution\, in nearly physiological conditions in the case of proteins\, and under full electrochemical control. ECSTM also allows performing conductance measurements by current-potential and current-distance tunneling spectroscopy. An overview of these methods and current projects in the laboratory will be presented\, with special emphasis on cytochromes of the respiratory chain and on photosystem I complexes. \nMore information about Pau Gorostiza’s research here \nThis seminar will be held using the TEAMS app
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-pau-gorostiza/
CATEGORIES:IBEC Seminar
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