BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Institute for Bioengineering of Catalonia - ECPv6.15.20//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-ORIGINAL-URL:https://ibecbarcelona.eu
X-WR-CALDESC:Events for Institute for Bioengineering of Catalonia
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:Europe/Madrid
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20230326T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20231029T010000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20240331T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20241027T010000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20250330T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20251026T010000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20240221T120000
DTEND;TZID=Europe/Madrid:20240221T133000
DTSTAMP:20260418T161111
CREATED:20240116T121948Z
LAST-MODIFIED:20240116T121948Z
UID:114154-1708516800-1708522200@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Ernesto Mejías
DESCRIPTION:Vaccinia in & as next-gen oncolytic virotherapy: exploiting the synergy between oncolysis and chemotherapy\nDr Ernesto Mejías Pérez Ramón y Cajal researcher Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC)\, Universidad de Córdoba. Dpto. de Biología Celular\, Fisiología e Inmunología \nIn the fight against cancer\, conventional treatments fall short of healthcare expectations. Oncolytic virotherapy is a versatile and robust alternative. With exceptional immunogenic features\, Vaccinia virus (VACV) is a standout oncolytic vector whose anti-tumor ability is usually enhanced by gene deletions for better safety and heterologous genes insertions for improved cytotoxicity. Yet\, VACV’s translation to effective anti-tumor treatments suffers from major shortcomings that warrant immediate solutions\, among those the limited efficacy as a standalone treatment need to be overcome. \nTo tackle this challenge head-on\, my laboratory is focused on developing next-generation synergistic therapeutic strategies towards strengthening the anti-tumor effects of the oncolytic virotherapy based on Vaccinia virus by boosting the infection efficacy and triggering a strong chemosensitization upon nucleoside analog treatment. This approach builds on the unique multifaceted role that SAMHD1 has at the interface oncolysis:chemotherapy.
URL:https://ibecbarcelona.eu/event/ibec-seminar-ernesto-mejias/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:IBEC Seminar
END:VEVENT
END:VCALENDAR