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DTSTART;TZID=Europe/Madrid:20260619T100000
DTEND;TZID=Europe/Madrid:20260619T110000
DTSTAMP:20260616T123335Z
CREATED:20260616T123335Z
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UID:134204-1781863200-1781866800@ibecbarcelona.eu
SUMMARY:Ibec Seminar. Ezequiel Coscueta
DESCRIPTION:Bioactives Beyond Screening: From Molecular Potential to Local Gut Function\nBioactive molecules are often selected through simplified screening assays\, where antioxidant\, antimicrobial\, anti-inflammatory or cytotoxic responses provide an initial indication of biological potential. However\, in the gastrointestinal context\, this potential can be profoundly reshaped by digestion\, solubility\, mucus\, microbiota metabolism\, epithelial interactions and the local biochemical conditions of health or disease. Moving beyond screening therefore requires asking not only whether a molecule is active\, but whether it can remain accessible\, transform into relevant metabolites\, interact with biological barriers and produce function where it is needed. \nThis talk will discuss how bioactives from complex biological matrices can be studied across this transition from molecular potential to gut-relevant function. Drawing on examples involving peptide-rich fractions\, peptidomics\, phenethyl isothiocyanate\, gastrointestinal simulation\, microbiota-oriented assays and delivery systems\, the talk will reflect on the experimental challenges of assigning biological meaning to bioactive molecules intended for local action in the gut. \nThe broader aim is to present a nutraceutical and molecular biotechnology perspective that connects naturally with current questions in gastrointestinal health\, local delivery and human-relevant models. In this context\, emerging biopolymeric and biocatalytic micro/nanosystems will be introduced as part of an ongoing effort to design bioactive-based strategies that respond more closely to the inflammatory gastrointestinal microenvironment. \n  \nEzequiel Coscueta is an Assistant Researcher at the Centro de Biotecnologia e Química Fina (CBQF) and an Invited Assistant Professor at the Faculty of Biotechnology\, Universidade Católica Portuguesa\, in Porto\, Portugal. He is currently undertaking a three-month research mobility at IBEC as a Visiting Researcher in the Smart Nano-Bio-Devices Group\, through an ongoing collaboration with the group leader\, Samuel Sánchez Ordóñez. He holds a PhD in Biological Sciences from Universidad Nacional de Rosario\, Argentina\, and a BSc in Biotechnology from Universidad Nacional del Litoral\, Argentina. His research combines molecular and analytical biotechnology\, peptidomics\, bioactive characterisation\, gastrointestinal digestion and colon fermentation models\, microbiota-oriented assays\, and bio-based delivery systems. \nHis scientific trajectory has evolved from bioprocessing and the study of complex biological matrices toward a broader interest in how bioactive molecules can become functionally relevant within the gastrointestinal environment. Rather than focusing only on simplified bioactivity screening\, his work addresses how digestion\, bioaccessibility\, microbial transformation\, biological barriers and local inflammatory conditions influence the functional potential of bioactives. \nHe is Principal Investigator of gBiOT\, a project funded by FCT\, the Fundação para a Ciência e a Tecnologia\, Portugal’s national public agency for science\, technology and innovation. He was also Co-Principal Investigator of GastroCure\, an ERDF-supported project\, funded through the European Regional Development Fund\, focused on bioactives for gastrointestinal inflammatory disorders. His current research explores bioactive-based strategies\, biopolymeric systems and biocatalytic micro/nanosystems designed for local action in inflammatory gastrointestinal microenvironments. In parallel\, he is working on bioactive peptides as modulators of the gut-skin axis\, with a particular focus on psoriasis\, expanding his research from local gastrointestinal function toward systemic inflammatory communication. Together\, these lines create natural points of contact with human-relevant models\, biological barriers\, local delivery and nanomedicine-oriented research.
URL:https://ibecbarcelona.eu/event/ibec-seminar-ezequiel-coscueta/
LOCATION:Baobab room\, Floor 11\, Tower 1
CATEGORIES:IBEC Seminar
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20260703T113000
DTEND;TZID=Europe/Madrid:20260703T123000
DTSTAMP:20260615T101020Z
CREATED:20260615T100943Z
LAST-MODIFIED:20260615T101020Z
UID:134198-1783078200-1783081800@ibecbarcelona.eu
SUMMARY:Ibec seminar. Dr Remy Chiaffarelli
DESCRIPTION:Hybrid PET/MR Imaging of Tumour Physiology: from Perfusion to Extracellular Lactate\nDr Remy Chiaffarelli\, Eberhard Karls University Tübingen \n\nTumour progression is driven by metabolic and vascular changes that shape the tumour microenvironment. We developed new hybrid PET/MRI probes to detect and quantify tumour physiology and its compartmentalization\, with a focus on extracellular lactate and perfusion. By combining responsive CEST MRI contrast agents with PET-based quantification\, these probes provide complementary functional and quantitative information for preclinical metabolic imaging. Our findings demonstrate the value of these approaches for characterising tumour heterogeneity and metabolic dynamics\, providing insights into cancer biology and supporting the development of more precise imaging biomarker.
URL:https://ibecbarcelona.eu/event/ibec-seminar-dr-remy-chiaffarelli/
LOCATION:Baobab room\, Floor 11\, Tower 1
CATEGORIES:IBEC Seminar
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20260917T143000
DTEND;TZID=Europe/Madrid:20260917T183000
DTSTAMP:20260910T110025Z
CREATED:20260701T104953Z
LAST-MODIFIED:20260910T110025Z
UID:134595-1789655400-1789669800@ibecbarcelona.eu
SUMMARY:Thematic Network. Final Retreat NET QUASI: Ways of Seeing
DESCRIPTION:Ways of Seeing \nNature is a master designer\, shaping molecules\, materials\, organisms\, and ecosystems through interactions across scales. Yet many of its most remarkable strategies remain hidden in plain sight\, waiting to be revealed through careful observation. Scientific discovery often begins not with a hypothesis\, but with a way of seeing: the ability to notice patterns\, ask unexpected questions\, and look at familiar phenomena from a different perspective. \nWith this retreat\, we would like to celebrate observation as a catalyst for curiosity\, understanding\, discovery\, and innovation. Together\, we will reflect on how attentiveness to the natural world inspires new ideas\, challenges existing assumptions\, and opens pathways to scientific and technological breakthroughs. Through the exchange of perspectives and experiences\, we hope to explore how careful observation can transform wonder into understanding\, and how insights from nature can inspire entirely new ways of designing \nAgenda: \n14:30 – 14:45 : Opening Remarks \n14:45 – 16:00: Keynote Lecture \n16:00–16:20 : Snack & Refreshments break \n16:20 – 17:50 : Documentary Screening: Observer. Director: Ian Cheney \n17:50 – 18:35: Round Table Discussion \nWays of Seeing: What Can Nature Still Teach Us? \n18:35: Closing Remarks \n  \nTo register click here.
URL:https://ibecbarcelona.eu/event/thematic-network-final-retreat-net-quasi-ways-of-seeing/
CATEGORIES:IBEC Seminar
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20260918T093000
DTEND;TZID=Europe/Madrid:20260918T153000
DTSTAMP:20260910T105831Z
CREATED:20260702T061239Z
LAST-MODIFIED:20260910T105831Z
UID:134616-1789723800-1789745400@ibecbarcelona.eu
SUMMARY:Thematic Network. NET-QUASI Workshop 4
DESCRIPTION:Constructing Biological Complexity: Engineering Interactions Across Scales\nBiological systems achieve remarkable functionality through interactions that span multiple scales\, from molecular assemblies and cellular compartments to tissues and complex microenvironments. Understanding how these interactions give rise to emergent behaviors is a central challenge in contemporary bioengineering and synthetic biology. \nThis workshop brings together researchers exploring how biological complexity can be reconstructed\, controlled\, and harnessed through engineering approaches. Topics range from the biochemical reconstitution of cellular processes and the design of synthetic cellular systems to mechanobiology\, collective cell behavior\, immune microenvironments\, and advanced therapeutic technologies. \nAgenda: \n09:30 – 09:40 Opening Remarks 09:40 – 10:35 Keynote Lecture I Prof. Dr. Germán Rivas (CIB Margarita Salas\, Spanish National Research Council (CSIC)\, Madrid\, Spain) Title: Synthetic Cell Division via Biochemical Reconstitution \n10:40 – 11:25 Invited Lecture I Dr. Margherita Staykova (Department of Physics\, Durham University\, UK) Title: Model lipid membranes for biophysical insights and for building living bio-hybrid systems \n11:25– 12:00 Coffee Break \n12:00 – 12:55 Keynote Lecture II Prof. Oskar Staufer (INM – Leibniz Institute for New Materials\, Saarbrücken\, Germany) Title: Building Immunity from the Bottom-Up: Synthetic Cell-Based Tumor Immune Microenvironments \n13:00 – 13:30 Early Career IBEC Lecture M.Sc. Inés Macías Tarrio (Institute for Bioengineering of Catalonia\, Spain) Title: Nanomotors Boost FGFR3-Targeted Therapy in Bladder Cancer \n13:30– 14:30 Lunch Break \n14:30 – 15:15 IBEC Lecture I Prof. Dr. Pere Roca-Cusachs (Institute for Bioengineering of Catalonia\, Spain) Title: Undertanding and controlling mechanotransduction through synthetic biology \n15:20 – 16:15 Keynote Lecture III Prof. Jerome Solon (Ikerbasque Research Professor\, Instituto Biofisika (CSIC-UPV/EHU)\, Leioa\, Spain) Title: How to seal epithelial gaps: Mechanosensing and control of tissue mechanics during embryonic wound healing \n16:15 – 16:30 Closing Remarks \nTo register click here
URL:https://ibecbarcelona.eu/event/thematic-network-net-quasi-workshop-4/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:IBEC Seminar
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DTSTART;TZID=Europe/Madrid:20260922T090000
DTEND;TZID=Europe/Madrid:20260922T133000
DTSTAMP:20260731T085046Z
CREATED:20260731T085046Z
LAST-MODIFIED:20260731T085046Z
UID:135425-1790067600-1790083800@ibecbarcelona.eu
SUMMARY:Jornada informativa 2026: Oportunidades de financiación para proyectos de investigación en salud
DESCRIPTION:Nanomed Spain e IBEC organizan esta Jornada Informativa para acercar a la comunidad investigadora y empresarial las principales oportunidades de financiación para proyectos de I+D+i en salud. \nA través de las intervenciones de representantes del CDTI y de la Fundación Científica de la AECC\, la jornada presentará las próximas convocatorias del programa Horizonte Europa\, los instrumentos nacionales de apoyo a la innovación y otras iniciativas de financiación estratégicas para impulsar la investigación\, la transferencia de tecnología y el desarrollo de soluciones innovadoras en salud. \nLa jornada culminará con una sesión de networking diseñada para identificar sinergias\, promover nuevas colaboraciones y facilitar la generación de consorcios para futuras propuestas nacionales e internacionales. \nUna oportunidad única para mantenerse al día de las novedades en financiación y ampliar la red de contactos dentro del ecosistema de innovación en salud. \n  \nPara registrarse hacer click aquí
URL:https://ibecbarcelona.eu/event/jornada-informativa-2026-oportunidades-de-financiacion-para-proyectos-de-investigacion-en-salud/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20261120T120000
DTEND;TZID=Europe/Madrid:20261120T130000
DTSTAMP:20260922T104004Z
CREATED:20260922T104004Z
LAST-MODIFIED:20260922T104004Z
UID:136182-1795176000-1795179600@ibecbarcelona.eu
SUMMARY:Ibec Seminar. Sara Mederos
DESCRIPTION:Brainwide circuits for adaptive decisions in response to threat\nSara Mederos\, neuroscientist and Ramón y Cajal group leader of NeuCompLab at the Hospital del Mar Research Institute  \nTo understand adaptive behavior\, we must understand how decisions are computed and updated through experience. For example\, when facing a potential threat\, animals may initially rely on  instinctive responses\, such as escape\, yet with experience they can suppress these reactions as the environment is reinterpreted. In this talk\, I will show how these transformations arise from  interactions between cortical and subcortical circuits that dynamically reshape decision  variables in aversive contexts. \nUsing an ethologically grounded paradigm in which mice escape from an overhead looming  stimulus that mimics an aerial predator\, I will show that repeated exposure leads to suppression of this instinctive response. We find that higher visual areas instruct this learning through projections to the inhibitory ventrolateral geniculate nucleus (vLGN). Neural population recordings reveal that specific vLGN neurons increase their activity across learning and are necessary for the expression of escape suppression\, indicating that cortical inputs instruct learning\, while plasticity within vLGN implements the learned behavioral change. \nI will then extend this framework to show how vLGN integrates inputs from retrosplenial cortex and hypothalamic circuits to regulate decisions between safety and exploration. These pathways carry distinct signals related to prior experience and internal state\, and their coordinated activity shapes when animals decide to leave safety. ogether\, these results reveal circuit mechanisms through which experience reshapes decision-making in aversive environments.\nFinally\, I will present ongoing work showing how acute stress induces persistent changes in hippocampal dynamics\, linking experience-dependent updating of threat with longer-lasting circuit adaptations that may be relevant for anxiety and PTSD. \n\nSara Mederos is a neuroscientist and Ramón y Cajal group leader of NeuCompLab at the Hospital del Mar Research Institute in Barcelona (neucomplab.com). She trained in \nBiochemistry and Neuroscience and completed her PhD in Perea’s lab at the Instituto Cajal (CSIC)\, where she studied communication between neurons and astrocytes\, contributing to \ndemonstrate that these cells actively participate in synaptic plasticity\, learning\, and goaldirected behaviour (Glia\, 2019; Nature Neuroscience\, 2021). During this period she also developed short research stays at the Buzsáki Lab (NYU) and the Ponomarenko Lab (HHU Düsseldorf). She subsequently developed her postdoctoral research in Hofer’s lab at the \nSainsbury Wellcome Centre\, University College London\, and later as an independent PI supported by a Wellcome Trust Early Career Award\, where she dissected the neuronal circuits and mechanisms underlying how experience and learning can modify instinctive responses such as fear (Science\, 2025). Her laboratory studies how the brain integrates information about the environment\, prior experience\, and internal states to make flexible decisions. Her research integrates advanced neuroscience techniques\, including in vivo electrophysiology in freely moving mice\, optogenetics\, in vitro electrophysiology\, and serial-section two-photon imaging\, to dissect the neural circuits underlying flexible decision-making. This work has provided new insights into how cortical and subcortical circuits interact to support learned safety and adaptive behaviour. Her research is supported by competitive international funding from the European Research Council\, the Wellcome Trust\, the AEI\, the BBRF\, and the BBVA Foundation. Among other recognitions\, she has received the FENS EJN Young Investigator Prize\, the Janett Rosenberg Trubatch Career Development Award\, and the L’Oréal-UNESCO For Women in Science Spain Award\, and was selected as a finalist for the Eppendorf & Science Prize for Neurobiology
URL:https://ibecbarcelona.eu/event/ibec-seminar-sara-mederos/
LOCATION:Baobab room\, Floor 11\, Tower 1
CATEGORIES:IBEC Seminar
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