BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Institute for Bioengineering of Catalonia - ECPv6.16.3//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-ORIGINAL-URL:https://ibecbarcelona.eu
X-WR-CALDESC:Events for Institute for Bioengineering of Catalonia
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:Europe/Madrid
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20250330T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20251026T010000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20260329T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20261025T010000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20270328T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20271031T010000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20260619T100000
DTEND;TZID=Europe/Madrid:20260619T110000
DTSTAMP:20260616T193555
CREATED:20260616T123335Z
LAST-MODIFIED:20260616T123335Z
UID:134204-1781863200-1781866800@ibecbarcelona.eu
SUMMARY:Ibec Seminar. Ezequiel Coscueta
DESCRIPTION:Bioactives Beyond Screening: From Molecular Potential to Local Gut Function\nBioactive molecules are often selected through simplified screening assays\, where antioxidant\, antimicrobial\, anti-inflammatory or cytotoxic responses provide an initial indication of biological potential. However\, in the gastrointestinal context\, this potential can be profoundly reshaped by digestion\, solubility\, mucus\, microbiota metabolism\, epithelial interactions and the local biochemical conditions of health or disease. Moving beyond screening therefore requires asking not only whether a molecule is active\, but whether it can remain accessible\, transform into relevant metabolites\, interact with biological barriers and produce function where it is needed. \nThis talk will discuss how bioactives from complex biological matrices can be studied across this transition from molecular potential to gut-relevant function. Drawing on examples involving peptide-rich fractions\, peptidomics\, phenethyl isothiocyanate\, gastrointestinal simulation\, microbiota-oriented assays and delivery systems\, the talk will reflect on the experimental challenges of assigning biological meaning to bioactive molecules intended for local action in the gut. \nThe broader aim is to present a nutraceutical and molecular biotechnology perspective that connects naturally with current questions in gastrointestinal health\, local delivery and human-relevant models. In this context\, emerging biopolymeric and biocatalytic micro/nanosystems will be introduced as part of an ongoing effort to design bioactive-based strategies that respond more closely to the inflammatory gastrointestinal microenvironment. \n  \nEzequiel Coscueta is an Assistant Researcher at the Centro de Biotecnologia e Química Fina (CBQF) and an Invited Assistant Professor at the Faculty of Biotechnology\, Universidade Católica Portuguesa\, in Porto\, Portugal. He is currently undertaking a three-month research mobility at IBEC as a Visiting Researcher in the Smart Nano-Bio-Devices Group\, through an ongoing collaboration with the group leader\, Samuel Sánchez Ordóñez. He holds a PhD in Biological Sciences from Universidad Nacional de Rosario\, Argentina\, and a BSc in Biotechnology from Universidad Nacional del Litoral\, Argentina. His research combines molecular and analytical biotechnology\, peptidomics\, bioactive characterisation\, gastrointestinal digestion and colon fermentation models\, microbiota-oriented assays\, and bio-based delivery systems. \nHis scientific trajectory has evolved from bioprocessing and the study of complex biological matrices toward a broader interest in how bioactive molecules can become functionally relevant within the gastrointestinal environment. Rather than focusing only on simplified bioactivity screening\, his work addresses how digestion\, bioaccessibility\, microbial transformation\, biological barriers and local inflammatory conditions influence the functional potential of bioactives. \nHe is Principal Investigator of gBiOT\, a project funded by FCT\, the Fundação para a Ciência e a Tecnologia\, Portugal’s national public agency for science\, technology and innovation. He was also Co-Principal Investigator of GastroCure\, an ERDF-supported project\, funded through the European Regional Development Fund\, focused on bioactives for gastrointestinal inflammatory disorders. His current research explores bioactive-based strategies\, biopolymeric systems and biocatalytic micro/nanosystems designed for local action in inflammatory gastrointestinal microenvironments. In parallel\, he is working on bioactive peptides as modulators of the gut-skin axis\, with a particular focus on psoriasis\, expanding his research from local gastrointestinal function toward systemic inflammatory communication. Together\, these lines create natural points of contact with human-relevant models\, biological barriers\, local delivery and nanomedicine-oriented research.
URL:https://ibecbarcelona.eu/event/ibec-seminar-ezequiel-coscueta/
LOCATION:Baobab room\, Floor 11\, Tower 1
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20260703T113000
DTEND;TZID=Europe/Madrid:20260703T123000
DTSTAMP:20260616T193555
CREATED:20260615T100943Z
LAST-MODIFIED:20260615T101020Z
UID:134198-1783078200-1783081800@ibecbarcelona.eu
SUMMARY:Ibec seminar. Dr Remy Chiaffarelli
DESCRIPTION:Hybrid PET/MR Imaging of Tumour Physiology: from Perfusion to Extracellular Lactate\nDr Remy Chiaffarelli\, Eberhard Karls University Tübingen \n\nTumour progression is driven by metabolic and vascular changes that shape the tumour microenvironment. We developed new hybrid PET/MRI probes to detect and quantify tumour physiology and its compartmentalization\, with a focus on extracellular lactate and perfusion. By combining responsive CEST MRI contrast agents with PET-based quantification\, these probes provide complementary functional and quantitative information for preclinical metabolic imaging. Our findings demonstrate the value of these approaches for characterising tumour heterogeneity and metabolic dynamics\, providing insights into cancer biology and supporting the development of more precise imaging biomarker.
URL:https://ibecbarcelona.eu/event/ibec-seminar-dr-remy-chiaffarelli/
LOCATION:Baobab room\, Floor 11\, Tower 1
CATEGORIES:IBEC Seminar
END:VEVENT
END:VCALENDAR