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UID:135425-1790067600-1790083800@ibecbarcelona.eu
SUMMARY:Jornada informativa 2026: Oportunidades de financiación para proyectos de investigación en salud
DESCRIPTION:Nanomed Spain e IBEC organizan esta Jornada Informativa para acercar a la comunidad investigadora y empresarial las principales oportunidades de financiación para proyectos de I+D+i en salud. \nA través de las intervenciones de representantes del CDTI y de la Fundación Científica de la AECC\, la jornada presentará las próximas convocatorias del programa Horizonte Europa\, los instrumentos nacionales de apoyo a la innovación y otras iniciativas de financiación estratégicas para impulsar la investigación\, la transferencia de tecnología y el desarrollo de soluciones innovadoras en salud. \nLa jornada culminará con una sesión de networking diseñada para identificar sinergias\, promover nuevas colaboraciones y facilitar la generación de consorcios para futuras propuestas nacionales e internacionales. \nUna oportunidad única para mantenerse al día de las novedades en financiación y ampliar la red de contactos dentro del ecosistema de innovación en salud. \n  \nPara registrarse hacer click aquí
URL:https://ibecbarcelona.eu/event/jornada-informativa-2026-oportunidades-de-financiacion-para-proyectos-de-investigacion-en-salud/
CATEGORIES:IBEC Seminar
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DTSTART;TZID=Europe/Madrid:20261120T120000
DTEND;TZID=Europe/Madrid:20261120T130000
DTSTAMP:20260922T104004Z
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UID:136182-1795176000-1795179600@ibecbarcelona.eu
SUMMARY:Ibec Seminar. Sara Mederos
DESCRIPTION:Brainwide circuits for adaptive decisions in response to threat\nSara Mederos\, neuroscientist and Ramón y Cajal group leader of NeuCompLab at the Hospital del Mar Research Institute  \nTo understand adaptive behavior\, we must understand how decisions are computed and updated through experience. For example\, when facing a potential threat\, animals may initially rely on  instinctive responses\, such as escape\, yet with experience they can suppress these reactions as the environment is reinterpreted. In this talk\, I will show how these transformations arise from  interactions between cortical and subcortical circuits that dynamically reshape decision  variables in aversive contexts. \nUsing an ethologically grounded paradigm in which mice escape from an overhead looming  stimulus that mimics an aerial predator\, I will show that repeated exposure leads to suppression of this instinctive response. We find that higher visual areas instruct this learning through projections to the inhibitory ventrolateral geniculate nucleus (vLGN). Neural population recordings reveal that specific vLGN neurons increase their activity across learning and are necessary for the expression of escape suppression\, indicating that cortical inputs instruct learning\, while plasticity within vLGN implements the learned behavioral change. \nI will then extend this framework to show how vLGN integrates inputs from retrosplenial cortex and hypothalamic circuits to regulate decisions between safety and exploration. These pathways carry distinct signals related to prior experience and internal state\, and their coordinated activity shapes when animals decide to leave safety. ogether\, these results reveal circuit mechanisms through which experience reshapes decision-making in aversive environments.\nFinally\, I will present ongoing work showing how acute stress induces persistent changes in hippocampal dynamics\, linking experience-dependent updating of threat with longer-lasting circuit adaptations that may be relevant for anxiety and PTSD. \n\nSara Mederos is a neuroscientist and Ramón y Cajal group leader of NeuCompLab at the Hospital del Mar Research Institute in Barcelona (neucomplab.com). She trained in \nBiochemistry and Neuroscience and completed her PhD in Perea’s lab at the Instituto Cajal (CSIC)\, where she studied communication between neurons and astrocytes\, contributing to \ndemonstrate that these cells actively participate in synaptic plasticity\, learning\, and goaldirected behaviour (Glia\, 2019; Nature Neuroscience\, 2021). During this period she also developed short research stays at the Buzsáki Lab (NYU) and the Ponomarenko Lab (HHU Düsseldorf). She subsequently developed her postdoctoral research in Hofer’s lab at the \nSainsbury Wellcome Centre\, University College London\, and later as an independent PI supported by a Wellcome Trust Early Career Award\, where she dissected the neuronal circuits and mechanisms underlying how experience and learning can modify instinctive responses such as fear (Science\, 2025). Her laboratory studies how the brain integrates information about the environment\, prior experience\, and internal states to make flexible decisions. Her research integrates advanced neuroscience techniques\, including in vivo electrophysiology in freely moving mice\, optogenetics\, in vitro electrophysiology\, and serial-section two-photon imaging\, to dissect the neural circuits underlying flexible decision-making. This work has provided new insights into how cortical and subcortical circuits interact to support learned safety and adaptive behaviour. Her research is supported by competitive international funding from the European Research Council\, the Wellcome Trust\, the AEI\, the BBRF\, and the BBVA Foundation. Among other recognitions\, she has received the FENS EJN Young Investigator Prize\, the Janett Rosenberg Trubatch Career Development Award\, and the L’Oréal-UNESCO For Women in Science Spain Award\, and was selected as a finalist for the Eppendorf & Science Prize for Neurobiology
URL:https://ibecbarcelona.eu/event/ibec-seminar-sara-mederos/
LOCATION:Baobab room\, Floor 11\, Tower 1
CATEGORIES:IBEC Seminar
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