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X-WR-CALNAME:Institute for Bioengineering of Catalonia
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X-WR-CALDESC:Events for Institute for Bioengineering of Catalonia
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20150410T100000
DTEND;TZID=Europe/Madrid:20150410T110000
DTSTAMP:20260424T003623
CREATED:20150119T102356Z
LAST-MODIFIED:20150119T102356Z
UID:95822-1428660000-1428663600@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Núria Montserrat
DESCRIPTION:Dreaming of organ regeneration: new hopes for regenerative medicine\n \nNúria Montserrat\, Pluripotent stem cells and activation of endogenous tissue programs for organ regeneration group\, IBEC\nDr. Montserrat became interested in organ regeneration and stem cells during her master in biological research and PhD training. She completed her PhD with Dr. Joaquim Gutiérrez and Isabel Navarro at the Faculty of Biology\, University of Barcelona in 2006. During her master and PhD studies\, she set-up in vitro platforms for the study of skeletal muscle stem cells during homeostasis and under different metabolic conditions. During her PhD studies she did several stages at other European laboratories: Manfred Reinecke’s laboratory at the University of Zurich and at Jean-Charles Gabillard’s laboratory in INRA SCRIBE\, France. In 2006\,Dr. Montserrat got her European PhD degree at the University of Barcelona. \nIn 2006 she got a Postdoctoral fellowship from the Fundaçao para a Ciência e Tecnología (Portugal) and in 2007 she was hired as a post-doctoral researcher at at the Hospital of Santa Creu i Sant Pau in Barcelona. Early in 2008 she joined the Center of Regenerative Medicine of Barcelona (CMRB) with the objective to study the molecular mechanisms driving tissue regeneration\, somatic reprogramming and disease modeling. \nThe research line of Dr.Montserrat has been awarded with an ERC Starting Grant within the call of 2014. Recently\, Dr. Montserrat has joined IBEC as Junior Group leader. Her aim is to develop strategies for tissue and organ engineering making use of pluripotent stem cells from patients and the reactivation of tissue endogenous programs.
URL:https://ibecbarcelona.eu/event/ibec-seminar-nuria-montserrat-2/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20150320T100000
DTEND;TZID=Europe/Madrid:20150320T110000
DTSTAMP:20260424T003623
CREATED:20150119T103657Z
LAST-MODIFIED:20150317T104438Z
UID:11715-1426845600-1426849200@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Romain Quidant
DESCRIPTION:Biomedical applications of nanoplasmonics\n \nRomain Quidant\, ICREA professor at Institut de Ciències Fotòniques (ICFO)\nGold nanostructures\, supporting localized surface plasmon resonances\, can be designed to act upon illumination as efficient point-like sources of either light or heat\, opening plenty of new science and applications in biology and medicine.  In this talk we discuss how both their optical and photothermal properties can be exploited to develop alternative\, minimally invasive strategies for the detection and therapy of cancer.   \nThe first part of this presentation focuses on the use of the intense and confined optical fields bound to gold nanostructures for biosensing and optical trapping. In the frame of sensing\, we show that gold nanostructures lithographically prepared on glass can be engineered as compact and highly sensitive sensors to detect low concentrations of cancer markers in serum.  As for optical trapping\, we demonstrate that plasmonic fields enable creating on-a-chip nano-optical tweezers able to trap a large number of micro- and nano- specimens with a single laser beam of low laser intensity.  \nIn the second part we talk about the use of gold nanoparticles as remotely controlled point-like sources of heat for photothermal cancer therapy. We first discuss\, both theoretically and experimentally\, the physics of heat generation at the nanoscale along with the effect of the particle shape and the illumination. We then present the use of conjugated gold nanoparticles for specific cancer cell hyperthermia.
URL:https://ibecbarcelona.eu/event/ibec-seminar-romain-quidant/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20150320T100000
DTEND;TZID=Europe/Madrid:20150320T110000
DTSTAMP:20260424T003623
CREATED:20150119T103657Z
LAST-MODIFIED:20150119T103657Z
UID:95834-1426845600-1426849200@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Romain Quidant
DESCRIPTION:Biomedical applications of nanoplasmonics\n \nRomain Quidant\, ICREA professor at Institut de Ciències Fotòniques (ICFO)\nGold nanostructures\, supporting localized surface plasmon resonances\, can be designed to act upon illumination as efficient point-like sources of either light or heat\, opening plenty of new science and applications in biology and medicine.  In this talk we discuss how both their optical and photothermal properties can be exploited to develop alternative\, minimally invasive strategies for the detection and therapy of cancer.   \nThe first part of this presentation focuses on the use of the intense and confined optical fields bound to gold nanostructures for biosensing and optical trapping. In the frame of sensing\, we show that gold nanostructures lithographically prepared on glass can be engineered as compact and highly sensitive sensors to detect low concentrations of cancer markers in serum.  As for optical trapping\, we demonstrate that plasmonic fields enable creating on-a-chip nano-optical tweezers able to trap a large number of micro- and nano- specimens with a single laser beam of low laser intensity.  \nIn the second part we talk about the use of gold nanoparticles as remotely controlled point-like sources of heat for photothermal cancer therapy. We first discuss\, both theoretically and experimentally\, the physics of heat generation at the nanoscale along with the effect of the particle shape and the illumination. We then present the use of conjugated gold nanoparticles for specific cancer cell hyperthermia.
URL:https://ibecbarcelona.eu/event/ibec-seminar-romain-quidant-2/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20150227T120000
DTEND;TZID=Europe/Madrid:20150227T130000
DTSTAMP:20260424T003623
CREATED:20150216T094336Z
LAST-MODIFIED:20150216T094336Z
UID:95838-1425038400-1425042000@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Gilles Subra
DESCRIPTION:Hybrid inorganic–biorganic peptide materials and polymers: a bottom-up approach\n \nGilles Subra\, Institut des Biomolécules Max Mousseron (IBBMM)\, Montpellier\nThe preparation of hybrid materials containing peptides relies most of the time on physical entrapment of the bioorganic moiety or on a ‘post-grafting’ procedure. In the later case\, introduction of the peptide requires surface modification and ligation chemistry performed after the synthesis of the material. In contrast\, we designed a new family of bioorganic-inorganic hybrid materials relying on the synthesis of hybrid peptide-trialkoxsilyl building blocks that can be engaged directly in a sol gel process requiring no extra reagents.  \nThis bottom-up approach permits the introduction of any type of peptide in the material\, providing different functionalities\, structural features\, biological and physicochemical properties. The hybrid peptide block can be either grafted or introduced by direct synthesis. Several applications will be presented including the synthesis of silica multifunctional nanoparticles for imaging\, peptide-catalytic mesopous materials\, anti fouling glass surfaces and hydrogels. At last\, the self-assembling properties of the peptide unit can be exploited to yield a range of bio-inspired nanostructured materials.  \nIn an effort to develop polymerization systems suitable for peptide sequences\, we also describe a new class of silicone-peptides biopolymers. We used well defined chlorosilyl hybrid peptides as mononeric units\, synthesized in solution or on dedicated solid support to yield linear or comb-like peptide polymers.
URL:https://ibecbarcelona.eu/event/ibec-seminar-gilles-subra-2/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20150227T120000
DTEND;TZID=Europe/Madrid:20150227T130000
DTSTAMP:20260424T003623
CREATED:20150216T094336Z
LAST-MODIFIED:20150224T111247Z
UID:13751-1425038400-1425042000@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Gilles Subra
DESCRIPTION:Hybrid inorganic–biorganic peptide materials and polymers: a bottom-up approach\n \nGilles Subra\, Institut des Biomolécules Max Mousseron (IBBMM)\, Montpellier\nThe preparation of hybrid materials containing peptides relies most of the time on physical entrapment of the bioorganic moiety or on a ‘post-grafting’ procedure. In the later case\, introduction of the peptide requires surface modification and ligation chemistry performed after the synthesis of the material. In contrast\, we designed a new family of bioorganic-inorganic hybrid materials relying on the synthesis of hybrid peptide-trialkoxsilyl building blocks that can be engaged directly in a sol gel process requiring no extra reagents.  \nThis bottom-up approach permits the introduction of any type of peptide in the material\, providing different functionalities\, structural features\, biological and physicochemical properties. The hybrid peptide block can be either grafted or introduced by direct synthesis. Several applications will be presented including the synthesis of silica multifunctional nanoparticles for imaging\, peptide-catalytic mesopous materials\, anti fouling glass surfaces and hydrogels. At last\, the self-assembling properties of the peptide unit can be exploited to yield a range of bio-inspired nanostructured materials.  \nIn an effort to develop polymerization systems suitable for peptide sequences\, we also describe a new class of silicone-peptides biopolymers. We used well defined chlorosilyl hybrid peptides as mononeric units\, synthesized in solution or on dedicated solid support to yield linear or comb-like peptide polymers.
URL:https://ibecbarcelona.eu/event/ibec-seminar-gilles-subra/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20150213T100000
DTEND;TZID=Europe/Madrid:20150213T110000
DTSTAMP:20260424T003623
CREATED:20141211T155529Z
LAST-MODIFIED:20141211T155529Z
UID:95817-1423821600-1423825200@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Pia Cosma
DESCRIPTION:Studying Wnt signaling activity in cell reprogramming and tissue regeneration\n \nPia Cosma\, Center for Genomic Regulation (CRG) / ICREA \nIn our group\, we are investigating the mechanisms controlling the reprogramming of somatic cells\, and our final goal is to determine if this reprogramming contributes to tissue regeneration in higher vertebrates. \nDifferentiation from zygotes has been considered as a unidirectional route in all cells of the body. Recently\, however\, it has become clear that the reverse path is also possible: the reprogramming of somatic nuclei\, i.e. the de-differentiation of somatic cells into pluripotent stem-like cells. To date\, reprogramming has been induced in vitro by transferring somatic nuclei into enucleated oocytes\, by fusing embryonic stem cells (ESCs) with somatic cells\, and by transferring specific factors into different types of somatic cell. \nWhether reprogramming can occur in vivo in higher vertebrates and what the molecular mechanisms and genes driving reprogramming are remain to be defined. We have recently shown that activation of the Wnt/β-catenin signalling pathway enhances reprogramming of somatic cells after their fusion with ESCs. Remarkably\, the activation of this signalling pathway also controls regeneration in response to damage in lower and higher vertebrates; furthermore\, cell fusion is one possible mechanism of regeneration in vertebrates. Our main goal is to determine whether in mice activation of Wnt/β-catenin signalling controls tissue regeneration by enhancing cell-fusion-mediated reprogramming.
URL:https://ibecbarcelona.eu/event/ibec-seminar-pia-cosma-2/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20150213T100000
DTEND;TZID=Europe/Madrid:20150213T110000
DTSTAMP:20260424T003623
CREATED:20141211T155529Z
LAST-MODIFIED:20150114T110203Z
UID:9306-1423821600-1423825200@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Pia Cosma
DESCRIPTION:Studying Wnt signaling activity in cell reprogramming and tissue regeneration\n \nPia Cosma\, Center for Genomic Regulation (CRG) / ICREA \nIn our group\, we are investigating the mechanisms controlling the reprogramming of somatic cells\, and our final goal is to determine if this reprogramming contributes to tissue regeneration in higher vertebrates. \nDifferentiation from zygotes has been considered as a unidirectional route in all cells of the body. Recently\, however\, it has become clear that the reverse path is also possible: the reprogramming of somatic nuclei\, i.e. the de-differentiation of somatic cells into pluripotent stem-like cells. To date\, reprogramming has been induced in vitro by transferring somatic nuclei into enucleated oocytes\, by fusing embryonic stem cells (ESCs) with somatic cells\, and by transferring specific factors into different types of somatic cell. \nWhether reprogramming can occur in vivo in higher vertebrates and what the molecular mechanisms and genes driving reprogramming are remain to be defined. We have recently shown that activation of the Wnt/β-catenin signalling pathway enhances reprogramming of somatic cells after their fusion with ESCs. Remarkably\, the activation of this signalling pathway also controls regeneration in response to damage in lower and higher vertebrates; furthermore\, cell fusion is one possible mechanism of regeneration in vertebrates. Our main goal is to determine whether in mice activation of Wnt/β-catenin signalling controls tissue regeneration by enhancing cell-fusion-mediated reprogramming.
URL:https://ibecbarcelona.eu/event/ibec-seminar-pia-cosma/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20150212T000000
DTEND;TZID=Europe/Madrid:20150212T130000
DTSTAMP:20260424T003623
CREATED:20150206T085944Z
LAST-MODIFIED:20150206T085944Z
UID:95837-1423699200-1423746000@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Daniel Oliver
DESCRIPTION:Crowdfunding for scientific and health projects\n \nDaniel Oliver\, Asociación Española de Crowdfunding\nMr. Oliver\, president of Spain CrowdFund\, will share his expertise fundraising for spinoff biotech companies. He will unveil the tricks that lead Iproteos to its success financing more than 100k€ through crowdfunding. Finally\, he will present Capital Cell as the first co-investment platform specialized in scientific and health projects.
URL:https://ibecbarcelona.eu/event/ibec-seminar-daniel-oliver-2/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20150212T000000
DTEND;TZID=Europe/Madrid:20150212T130000
DTSTAMP:20260424T003623
CREATED:20150206T085944Z
LAST-MODIFIED:20150206T085944Z
UID:12342-1423699200-1423746000@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Daniel Oliver
DESCRIPTION:Crowdfunding for scientific and health projects\n \nDaniel Oliver\, Asociación Española de Crowdfunding\nMr. Oliver\, president of Spain CrowdFund\, will share his expertise fundraising for spinoff biotech companies. He will unveil the tricks that lead Iproteos to its success financing more than 100k€ through crowdfunding. Finally\, he will present Capital Cell as the first co-investment platform specialized in scientific and health projects.
URL:https://ibecbarcelona.eu/event/ibec-seminar-daniel-oliver/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20150203T100000
DTEND;TZID=Europe/Madrid:20150203T110000
DTSTAMP:20260424T003623
CREATED:20150119T102254Z
LAST-MODIFIED:20150119T102254Z
UID:95821-1422957600-1422961200@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Ralph G. Andrzejak
DESCRIPTION:Application of nonlinear signal analysis to electroencephalographic recordings from epilepsy patients\n \nTenure Associate Professor · Department of Information and Communication Technologies · Universitat Pompeu Fabra\nNonlinear time series analysis allows characterizing dynamical systems in which nonlinearity gives rise to a complex\, seemingly irregular temporal evolution. Importantly\, these nonlinear techniques can extract information from real-world experimental signals that cannot be resolved by classical linear techniques\, such as spectral analysis. Nonlinear time series analysis can\, for example\, help to discriminate nonlinear deterministic and linear stochastic dynamics or to characterize directional interactions between dynamics. In application to signals measured from the brain\, this analysis can contribute to the understanding of brain functions and dysfunctions. It can thereby advance cognitive neuroscience and neurology. \nIn this seminar\, I will at first illustrate some fundamental concepts of nonlinear time series analysis. Subsequently\, we will review some basic facts about the disease epilepsy\, epilepsy surgery and intracranial electroencephalographic recordings (EEG) from epilepsy patients. I will then show an application of nonlinear time series analysis to EEG recordings from the seizure-free interval of epilepsy patients undergoing pre-surgical diagnostics.  Results of this application allowed us to localize the seizure generating brain area without the necessity of observing actual seizure activity – a finding of clear clinical relevance.
URL:https://ibecbarcelona.eu/event/ibec-seminar-danny-van-noort-2/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20150203T100000
DTEND;TZID=Europe/Madrid:20150203T110000
DTSTAMP:20260424T003623
CREATED:20150119T102254Z
LAST-MODIFIED:20150128T103719Z
UID:11712-1422957600-1422961200@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Ralph G. Andrzejak
DESCRIPTION:Application of nonlinear signal analysis to electroencephalographic recordings from epilepsy patients\n \nTenure Associate Professor · Department of Information and Communication Technologies · Universitat Pompeu Fabra\nNonlinear time series analysis allows characterizing dynamical systems in which nonlinearity gives rise to a complex\, seemingly irregular temporal evolution. Importantly\, these nonlinear techniques can extract information from real-world experimental signals that cannot be resolved by classical linear techniques\, such as spectral analysis. Nonlinear time series analysis can\, for example\, help to discriminate nonlinear deterministic and linear stochastic dynamics or to characterize directional interactions between dynamics. In application to signals measured from the brain\, this analysis can contribute to the understanding of brain functions and dysfunctions. It can thereby advance cognitive neuroscience and neurology. \nIn this seminar\, I will at first illustrate some fundamental concepts of nonlinear time series analysis. Subsequently\, we will review some basic facts about the disease epilepsy\, epilepsy surgery and intracranial electroencephalographic recordings (EEG) from epilepsy patients. I will then show an application of nonlinear time series analysis to EEG recordings from the seizure-free interval of epilepsy patients undergoing pre-surgical diagnostics.  Results of this application allowed us to localize the seizure generating brain area without the necessity of observing actual seizure activity – a finding of clear clinical relevance.
URL:https://ibecbarcelona.eu/event/ibec-seminar-danny-van-noort/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20150116T100000
DTEND;TZID=Europe/Madrid:20150116T110000
DTSTAMP:20260424T003623
CREATED:20141113T150633Z
LAST-MODIFIED:20141113T150633Z
UID:95816-1421402400-1421406000@ibecbarcelona.eu
SUMMARY:IBEC Seminar: David Caballero
DESCRIPTION:The cell ratchet: interplay between protrusion activity and adhesion determines cell motion\n \nDavid Caballero\, Nanobioengineering group\, IBEC\nMany physiological and pathological processes involve directed cell motion\, either collective or as single cells. Typically\, migrating cells are characterized by a polarized morphology with extending and retracting protrusions at the leading edge. However\, cell motion is a much more complex phenomenon. Cells show heterogeneous morphologies and high protrusive dynamics. This prevents the quantitative prediction of cell motion and the identification of the cellular mechanism responsible of directionality. In this seminar\, I discuss about the importance of protrusion fluctuations in the physicochemical mechanism of directed cell motion. I show how their spatiotemporal distribution and dynamics determines univocally the direction of cell motion on NIH3T3 fibroblasts deposited on micropatterned adhesive ratchets. Novel physical concepts describing short-term cell motility are introduced which allows the prediction of parameters characteristic of long-term motion of cells. The obtained results may have important implications for the study of biological phenomena where directed cell migration is involved\, such as morphogenesis or cancer.
URL:https://ibecbarcelona.eu/event/ibec-seminar-david-caballero-ibec-2/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20150116T100000
DTEND;TZID=Europe/Madrid:20150116T110000
DTSTAMP:20260424T003623
CREATED:20141113T150633Z
LAST-MODIFIED:20150112T161125Z
UID:2488-1421402400-1421406000@ibecbarcelona.eu
SUMMARY:IBEC Seminar: David Caballero
DESCRIPTION:The cell ratchet: interplay between protrusion activity and adhesion determines cell motion\n \nDavid Caballero\, Nanobioengineering group\, IBEC\nMany physiological and pathological processes involve directed cell motion\, either collective or as single cells. Typically\, migrating cells are characterized by a polarized morphology with extending and retracting protrusions at the leading edge. However\, cell motion is a much more complex phenomenon. Cells show heterogeneous morphologies and high protrusive dynamics. This prevents the quantitative prediction of cell motion and the identification of the cellular mechanism responsible of directionality. In this seminar\, I discuss about the importance of protrusion fluctuations in the physicochemical mechanism of directed cell motion. I show how their spatiotemporal distribution and dynamics determines univocally the direction of cell motion on NIH3T3 fibroblasts deposited on micropatterned adhesive ratchets. Novel physical concepts describing short-term cell motility are introduced which allows the prediction of parameters characteristic of long-term motion of cells. The obtained results may have important implications for the study of biological phenomena where directed cell migration is involved\, such as morphogenesis or cancer.
URL:https://ibecbarcelona.eu/event/ibec-seminar-david-caballero-ibec/
CATEGORIES:IBEC Seminar
END:VEVENT
END:VCALENDAR