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DTSTART;TZID=Europe/Madrid:20150203T100000
DTEND;TZID=Europe/Madrid:20150203T110000
DTSTAMP:20260424T020605
CREATED:20150119T102254Z
LAST-MODIFIED:20150119T102254Z
UID:95821-1422957600-1422961200@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Ralph G. Andrzejak
DESCRIPTION:Application of nonlinear signal analysis to electroencephalographic recordings from epilepsy patients\n \nTenure Associate Professor · Department of Information and Communication Technologies · Universitat Pompeu Fabra\nNonlinear time series analysis allows characterizing dynamical systems in which nonlinearity gives rise to a complex\, seemingly irregular temporal evolution. Importantly\, these nonlinear techniques can extract information from real-world experimental signals that cannot be resolved by classical linear techniques\, such as spectral analysis. Nonlinear time series analysis can\, for example\, help to discriminate nonlinear deterministic and linear stochastic dynamics or to characterize directional interactions between dynamics. In application to signals measured from the brain\, this analysis can contribute to the understanding of brain functions and dysfunctions. It can thereby advance cognitive neuroscience and neurology. \nIn this seminar\, I will at first illustrate some fundamental concepts of nonlinear time series analysis. Subsequently\, we will review some basic facts about the disease epilepsy\, epilepsy surgery and intracranial electroencephalographic recordings (EEG) from epilepsy patients. I will then show an application of nonlinear time series analysis to EEG recordings from the seizure-free interval of epilepsy patients undergoing pre-surgical diagnostics.  Results of this application allowed us to localize the seizure generating brain area without the necessity of observing actual seizure activity – a finding of clear clinical relevance.
URL:https://ibecbarcelona.eu/event/ibec-seminar-danny-van-noort-2/
CATEGORIES:IBEC Seminar
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20150116T100000
DTEND;TZID=Europe/Madrid:20150116T110000
DTSTAMP:20260424T020605
CREATED:20141113T150633Z
LAST-MODIFIED:20141113T150633Z
UID:95816-1421402400-1421406000@ibecbarcelona.eu
SUMMARY:IBEC Seminar: David Caballero
DESCRIPTION:The cell ratchet: interplay between protrusion activity and adhesion determines cell motion\n \nDavid Caballero\, Nanobioengineering group\, IBEC\nMany physiological and pathological processes involve directed cell motion\, either collective or as single cells. Typically\, migrating cells are characterized by a polarized morphology with extending and retracting protrusions at the leading edge. However\, cell motion is a much more complex phenomenon. Cells show heterogeneous morphologies and high protrusive dynamics. This prevents the quantitative prediction of cell motion and the identification of the cellular mechanism responsible of directionality. In this seminar\, I discuss about the importance of protrusion fluctuations in the physicochemical mechanism of directed cell motion. I show how their spatiotemporal distribution and dynamics determines univocally the direction of cell motion on NIH3T3 fibroblasts deposited on micropatterned adhesive ratchets. Novel physical concepts describing short-term cell motility are introduced which allows the prediction of parameters characteristic of long-term motion of cells. The obtained results may have important implications for the study of biological phenomena where directed cell migration is involved\, such as morphogenesis or cancer.
URL:https://ibecbarcelona.eu/event/ibec-seminar-david-caballero-ibec-2/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20150116T100000
DTEND;TZID=Europe/Madrid:20150116T110000
DTSTAMP:20260424T020605
CREATED:20141113T150633Z
LAST-MODIFIED:20150112T161125Z
UID:2488-1421402400-1421406000@ibecbarcelona.eu
SUMMARY:IBEC Seminar: David Caballero
DESCRIPTION:The cell ratchet: interplay between protrusion activity and adhesion determines cell motion\n \nDavid Caballero\, Nanobioengineering group\, IBEC\nMany physiological and pathological processes involve directed cell motion\, either collective or as single cells. Typically\, migrating cells are characterized by a polarized morphology with extending and retracting protrusions at the leading edge. However\, cell motion is a much more complex phenomenon. Cells show heterogeneous morphologies and high protrusive dynamics. This prevents the quantitative prediction of cell motion and the identification of the cellular mechanism responsible of directionality. In this seminar\, I discuss about the importance of protrusion fluctuations in the physicochemical mechanism of directed cell motion. I show how their spatiotemporal distribution and dynamics determines univocally the direction of cell motion on NIH3T3 fibroblasts deposited on micropatterned adhesive ratchets. Novel physical concepts describing short-term cell motility are introduced which allows the prediction of parameters characteristic of long-term motion of cells. The obtained results may have important implications for the study of biological phenomena where directed cell migration is involved\, such as morphogenesis or cancer.
URL:https://ibecbarcelona.eu/event/ibec-seminar-david-caballero-ibec/
CATEGORIES:IBEC Seminar
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