BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Institute for Bioengineering of Catalonia - ECPv6.15.20//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Institute for Bioengineering of Catalonia
X-ORIGINAL-URL:https://ibecbarcelona.eu
X-WR-CALDESC:Events for Institute for Bioengineering of Catalonia
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:Europe/Madrid
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20220327T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20221030T010000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20230326T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20231029T010000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20240331T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20241027T010000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20250330T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20251026T010000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20260329T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20261025T010000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231215T100000
DTEND;TZID=Europe/Madrid:20231215T110000
DTSTAMP:20260425T022730
CREATED:20231127T122753Z
LAST-MODIFIED:20231204T154540Z
UID:112845-1702634400-1702638000@ibecbarcelona.eu
SUMMARY:PhD Discussions: Zhendong Xie and Júlia Alcàcer
DESCRIPTION:Integrating phenotypic targeting in physiologically-based pharmacokinetics modeling.\nZhendong Xie\, Molecular Bionics group \nSelective drugging\, also known as the “magic bullet\,” is the concept that drugs can target specific molecules\, cells\, or targets while minimising interactions with other parts of the body. Nanoparticles (NPs) with functioned ligands target cells with a certain range of receptors due to the multivalent effect. To develop precision drugs\, it is crucial to understand how NPs are distributed in different organs and interact with different cell types in vivo. Our focus is on investigating the distribution of poly(2-(methacryloyloxy)ethylphosphorylcholine)-poly(2-(diisopropyl-amino)ethyl methacrylate) (PMPC-PDPA) polymersome. We use the PMPC polymersome’s interactions with different receptors to target specific cell groups based on phenotypic association theory (PAT)\, a statistical model based on the description between nanocarriers and cell phenotype (receptor density and glycocalyx). \nWe integrate phenotypic targeting in physiologically-based pharmacokinetics modeling (PBPK) to mimic the distribution of NPs in organs in silico to identify the most selective combination of parameters for precision drugs. The PBPK is built based on the circulation system\, anatomy data\, and cell protein atlas to predict the distribution of NPs among different organs\, considering the advection among various biological fluids\, diffusion of NPs in different organs\, and NPs’ interaction with different cells. A non-Langmiur differential rate equation (NLDRE) is applied to extrapolate the PMPC-cell interaction kinetics based on single-cell level uptake experiments. The association constant/affinity kA/j is derived from the PAT to reveal the selectivity of NPs to different cells. We propose that the difference in kA/j results in a larger distribution and cell targeting discrimination. \nThrough experiments in vivo\, we obtained information about drug distribution among different organs\, the selectivity of NPs to different cells\, and some undetectable parameters such as glycocalyx density. Based on these parameters\, we change the injected dose\, the NP radius\, and the polymerization of the PMPC ligand to simulate the distribution of PMPC in silico and develop a better administration strategy. \n\nExploring host-pathogen interactions: Unraveling the dynamics of Pseudomonas aeruginosa and Burkholderia cenocepacia infection in Galleria mellonella\nJúlia Alcàcer\, Bacterial infections: antimicrobial therapies group \nPseudomonas aeruginosa and Burkholderia cenocepacia are two multidrug-resistant opportunistic pathogens often isolated from the lungs of cystic fibrosis patients. It is known that the presence of more than one species in an infection promotes the appearance of a network of interactions that can lead to an increase in their antimicrobial tolerance or to the evasion of the host immune system. Galleria mellonella has been used as an animal model throughout this study\, as its immune system is comparable to that of mammals\, and it presents practical advantages such as their easy maintenance. With the aim of understanding bacterial and host behaviors after infection\, the survival rate of Galleria mellonella after a P. aeruginosa and B. cenocepacia single and dual-species infection was monitored\, as well as the efficacy of antibiotic treatment to such infections. In order to characterize the infection evolution\, the tissue-specific infection dissemination and hemocyte phagocytosis were evaluated through confocal microscopy.
URL:https://ibecbarcelona.eu/event/phd-discussions-zhendong-xie-and-julia-alcacer/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:PhD Discussions Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20240126T100000
DTEND;TZID=Europe/Madrid:20240126T110000
DTSTAMP:20260425T022730
CREATED:20231128T135726Z
LAST-MODIFIED:20240119T112549Z
UID:112917-1706263200-1706266800@ibecbarcelona.eu
SUMMARY:PhD Discussions: Ainhoa Ferret and Marta Badia
DESCRIPTION:3D bioengineered liver for the study of acute and chronic hepatic damage\nAinhoa Ferret\, Biosensors for bioengineering group \nThe liver\, a vital organ\, faces acute and chronic insults that disrupt its normal function. Understanding the mechanisms underlying acute and chronic liver damage is crucial for developing effective treatments. Traditional liver models face several limitations. As a result\, 3D models have emerged as a more physiologically cellular microenvironment for investigating disease progression\, identifying potential therapeutic targets\, and developing new drugs. We developed a 3D liver using human hepatocytes\, HSCs\, and monocytes. The cells were encapsulated in a mixture of GelMA and CMCMA\, and LAP as a photo-initiator. The 3D livers were kept in culture for up to 30 days in serum-free medium. They were challenged with acetaminophen and LPS (APAP-LPS)\, known hepatotoxic compounds\, to recreate the pathophysiological phenotype of liver damage in vitro. Extensive liver damage characterized by hepatic stellate cell (HSC) activation and proliferation was observed upon challenge with APAP-LPS. In vivo\, these cells exhibited the myofibroblast phenotype typical of activated HSCs. Additionally\, impaired gene expression of hepatocyte functionality markers was observed. The transition from monocytes to proinflammatory cytokine-releasing macrophages measured the inflammation level. Notably\, dexamethasone demonstrated potent beneficial effects\, reducing hepatocyte damage\, inhibiting HSC activation\, and decreasing collagen production. These results were observed in both acute (high APAP-LPS concentration/3 days) and chronic (low APAP-LPS concentration/30 days) models. The 3D model presented here demonstrates its value as a versatile platform for drug screening in both acute and chronic liver damage scenarios. Its ability to reproduce critical features of liver pathophysiology\, including hepatocyte functionality impairment\, HSC activation\, and inflammation\, makes it a valuable tool for studying liver diseases and evaluating potential therapeutic interventions. Furthermore\, the adaptability of this model for high-throughput screening provides an opportunity to accelerate the drug discovery process and improve patient outcomes in liver damage-related conditions. \n  \nDisclosures \nConflict of interest: This study is supported by Grifols. \n  \n\nWhat makes a prion behave like a prion? Lessons from deep mutagenesis\nMarta Badia\, Protein phase transitions in health and disease group \nPrions are proteins capable of promoting conformational changes of other protein isoforms. When prion proteins switch from a soluble (non-prion) state to a misfolded (prion) state\, they can bind to each other forming small nuclei that can rapidly incorporate other monomers and form amyloid-like aggregates. Subtle differences in the sequence of prionic proteins are enough to impair the recruitment of monomers into these small nuclei\, creating a barrier for the nucleation of aggregates. Learning how this barrier is established (and overcome) is fundamental to explain prion nucleation and to understand cross-species prion infection. \nYeast prions serve as a good and tractable model to study amyloid formation and protein aggregation. Sup35 is one of the most intensively studied yeast prions and its N-terminal domain is sufficient for prion nucleation and the maintenance of its prionic state. However\, the mechanisms by which Sup35 starts nucleating amyloid aggregates and the features that prevent this nucleation still need to be elucidated. \nUsing deep mutagenesis\, we built a library encompassing all single amino acid changes in the QN-rich region (aa 2-40) of the Sup35 N-terminal domain. We then employed a massively parallel approach that combines high-throughput sequencing with a selection assay that is able to measure Sup35 nucleation in yeast cells. \nBy systematically quantifying the effect of hundreds of mutants in the QN-rich domain of Sup35 we determined the compatibility of each mutation with an effective Sup35 nucleation. Thanks to this dataset\, we identified a nine-residue segment (residues 17-25) crucial for this process. On the other hand\, our comprehensive dataset also uncovers mutants that increase Sup35 nucleation\, gaining mechanistic insights on the nucleation of this model system and how prion species barriers can be overcome.
URL:https://ibecbarcelona.eu/event/phd-discussions-ainoa-ferret-and-marta-badia/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:PhD Discussions Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20240301T100000
DTEND;TZID=Europe/Madrid:20240301T110000
DTSTAMP:20260425T022730
CREATED:20240219T144047Z
LAST-MODIFIED:20240222T105448Z
UID:115601-1709287200-1709290800@ibecbarcelona.eu
SUMMARY:PhD Discussions: Alba Herrero y Clement Hallopeau
DESCRIPTION:Molecular imaging to unveil the pathophysiology of metabolic associated fatty liver disease\nAlba Herrero\, Molecular Imaging for Precision Medicine group \nMetabolic-associated fatty liver disease (MAFLD)\, a progressive liver condition rapidly rising to lead to chronic liver disease worldwide\, manifests as metabolic dysregulation\, leading to steatosis\, fibrosis\, and cirrhosis if left untreated. Beyond the liver\, it induces high BMI\, insulin resistance\, and elevated plasma glucose amongst others. Age\, genetics\, and sex influence its clinical presentation\, hindering biomarker detection. Currently\, real-time metabolic monitoring is not readily available in clinical settings. Hyperpolarized Magnetic Resonance Spectroscopic Imaging (HP-MRSI) boosts MR signals\, allowing for real-time metabolic tracking of 13C-labelled substrates\, such as pyruvate\, posing as a solution to this problem.\nWe delineated 6 study groups to evaluate the effects on liver metabolism of specific MAFLD risk factors\, these being diet\, sex\, and genetics. Subjects were monitored throughout the experiment for signs of insulin resistance\, increased plasma glucose\, and BMI levels as MAFLD indicators. Analyzed with a 3T preclinical MRI scanner\, and after injection of hyperpolarized [1-13C]-pyruvate\, the metabolism of pyruvate was tracked in situ\, probing downstream metabolic products such as lactate and alanine.\nMetabolic imaging has the potential to be used in clinical settings to diagnose and track metabolic dysfunctions. Real-time monitoring of pyruvate metabolism using HP-MRSI has revealed alterations across various metabolic conditions\, displaying its clinical potential. \n\nMechanisms of mechanical compartmentalisation in intestinal organoids\nClement Hallopeau\, Integrative Cell and Tissue Dynamics group \nMonolayers of intestinal organoids recapitulate the functional compartmentalisation seen in-vivo.\nCrypt-like regions host stem cells\, Paneth cells and transit amplifying cells\, whereas villus-like regions contain differentiated cells. Measurements of traction forces in these organoids have\nestablished that stem cells push the underlying substrate while the transit-amplifying cells pull it\, defining clear mechanical and functional compartments (Pérez-González\, Ceada et al\, Nat Cell Bio\, 2021). Crypt-villus compartmentalisation is attributed to opposed gradients in Eph/ephrin signaling\, but how these gradients are linked to the mechanical pattern is unknown. To address this question\, we studied the mechanical and functional compartmentalisation in organoids derived from mice lacking EphB2 and EphB3 (EphB2-/-\, EphB3-/-). We found that\, unlike in wild type organoids (WT)\, crypts of EphB2-/-EphB3-/- organoids (KO) expand at the expense of the villuslike region. This phenotype is associated to an increased proliferation of the KO crypts and a decreased expression of the stemness marker olfm4. In mechanical terms\, the 3D traction pattern of the KO crypts is qualitatively similar to the WT\, but forces have a decreased amplitude\, suggesting a decreased tension around the KO crypts. Taken together\, these data establish a link between the mechanical features and the size homeostasis of the functional compartments of the intestinal organoid\, governed by Eph/ephrin signaling.
URL:https://ibecbarcelona.eu/event/phd-discussions-alba-herrero-y-clement-hallopeau/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:PhD Discussions Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20240405T100000
DTEND;TZID=Europe/Madrid:20240405T110000
DTSTAMP:20260425T022730
CREATED:20240307T114216Z
LAST-MODIFIED:20240326T130314Z
UID:115873-1712311200-1712314800@ibecbarcelona.eu
SUMMARY:PhD discussions: Gülsun Bagci and Joana Admella
DESCRIPTION:Cell-Derived Extracellular Matrices for 3D in vitro Tumor Models\nGülsun Bagci\, Biomaterials for Regenerative Therapies Group \nDecellularized Extracellular matrices are new scaffolds for bioengineering of 3D tumor-ECM in vitro models. The tunable composition\, properties\, and structure of Cell-derived Matrices (CDMs) make them versatile and easy to use by using desired cell types. Moreover\, deposition of ECM can be achieved by adding specific stimulants such as Macromolecular crowding (MMC) like Ficoll/dextran sulfate or treating with hypoxia/starvation. Our aim is to fabricate CDM by two strategies as 2D culture CDMs from human dermal fibroblasts (hDFs)  or 3D culture CDM from bone marrow human mesenchymal stem cells (BM-hMSCs)/Human Adipose-derived stem cells (hAMSCs) in the presence of MMC/Ascorbic acid/ TGFβ-1  on Poly Lactic acid (PLA) derived microparticles (MPs) to generate 3D and 2D culture CDMs\, which can be used as scaffold for reseeding cancer cells or used as bioinks to generate tumor models for cancer research and for testing anti-cancer drugs. \nIn this study\, we generated 2D culture CDM from hDFs and 3D culture CDMs of BM-hMSCs and hAMSCs. To prepare 2D CDMs\, hDF were treated with Ascorbic acid (AA) or Ficoll\, AA\, TGFβ-1 combination for 2-weeks to increase the deposition of CDM. To fabricate 3D culture CDM\, cells were cultured into PLA MPs. MPs were produced by jet break-up method\, and their size distribution was calculated by ImageJ whereas their porosity was imaged under SEM. Moreover\, MPs were functionalized with fibronectin to enhance the cell adhesion. hMSCs/hAMSCs were seeded on MPs in a spinner flask for 8 hours. Then\, cell-seeded MPs were cultured for 2 weeks to produce CDM. The cellular viability and cell seeding in the MPs were evaluated. The ECM production before and after decellularization was evaluated by BCA\, hydroxyproline\, SEM\, qRT-PCR\, and immunofluorescence. Values were normalized by the total DNA. Microtissues and cells on 2D culture were also decellularized with 50mM NH4OH\, 0.05% TritonX-100 solution and characterized. \nBased on our results\, for hDF cells; Ficoll\, TGFβ-1 and Ascorbic acid combination\, and also ascorbic acid alone treatments increased total protein and total collagen production. For BM-hMSCs\, total collagen and protein after 2-weeks incubation was increased significantly in the presence of Ascorbic acid condition on the fibronectin coated MPs. AA increased total protein and total collagen production for hAMSCs at 3D culture. \nCDMs are promising and tunable biomaterials to establish 3D in vitro tumor models for cancer research. This platform possess a powerful potential for testing anti-cancer drugs  for personalized medicine in the coming years. \n\nExploring the potential of Galleria mellonella for the study of bacterial infections\nJoana Admella\, Bacterial Infections: Antimicrobial Therapies Group \nBacterial infections are becoming more threatening every day. Pathogens such as Pseudomonas aeruginosa\, Staphylococcus aureus\, Mycobacterium abscessus\, or Burkholderia cenocepacia pose significant challenges due to antimicrobial resistance. Our group has extensive experience in studying pathogenic microorganisms\, with a focus on understanding bacterial virulence and biofilm formation. \nThe insect Galleria mellonella is an alternative animal model widely used for studying bacterial infections and evaluating the toxicity of various molecules and materials. It presents a wide range of advantages\, including low cost\, easy maintenance\, and lack of ethical constraints. Furthermore\, very precise doses can be injected\, facilitating the testing of diverse treatments like antibiotics\, nanomedicines\, or even bacteriophages. Notably\, their innate immune system closely resembles that of mammals\, encompassing both cellular and humoral defenses. These features make Galleria mellonella a very valuable model for investigating host-pathogen interactions\, infection dissemination\, and immune response. Here\, we present an overview of this animal model\, showing a variety of methodologies and applications that have enhanced our understanding of bacterial infections and expanded our knowledge of this insect.
URL:https://ibecbarcelona.eu/event/phd-discussions-gulsun-bagci-and-joana-admella/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:PhD Discussions Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20241213T100000
DTEND;TZID=Europe/Madrid:20241213T110000
DTSTAMP:20260425T022730
CREATED:20241122T100707Z
LAST-MODIFIED:20241210T142747Z
UID:121781-1734084000-1734087600@ibecbarcelona.eu
SUMMARY:PhD Discussion: Anna Panteleeva and Miguel Gonzalez Martin
DESCRIPTION:Advancing Neurodegenerative Disease Research with Enhanced Brain-on-a-Chip Technology and Integrated Biosensor Systems \nAnna Panteleeva – Nanobioengineering\nNeurodegenerative disorders (NDDs)\, such as Alzheimer’s disease\, remain a critical global health challenge. A key obstacle in drug development is the blood-brain barrier (BBB)\, which plays a crucial role in regulating the exchange of substances between the bloodstream and the brain. While the BBB protects the brain\, its dysfunction contributes to NDD progression\, and it hinders drug delivery\, leaving most therapeutic candidates unsuccessful in clinical trials.\nTraditional animal models have provided valuable insights into NDDs\, but they fall short in fully replicating the complexity of human neural responses. Brain-on-a-chip (BoC) technology has emerged as a promising tool\, offering controlled environments to study neuronal networks. Integrating a BBB component into BoC systems significantly enhances their physiological relevance\, enabling the study of complex BBB properties.\nOur research advances BoC technology by combining a microfluidic device\, multi-electrode array (MEA) technology and biosensors to create a comprehensive BBB model. By co-culturing endothelial cells\, pericytes\, astrocytes\, and neurons\, we replicate key BBB elements and neural interactions. This setup allows real-time monitoring of BBB permeability and neural activity via MEA electrodes\, and neuronal degradation using biosensors. Preliminary results demonstrate promising outcomes\, though further optimization is required.\nThis innovative approach improves the physiological relevance of BoC systems and accelerates drug development and personalized therapies for NDDs\, providing a pathway toward more effective treatments. \nDesigning synthetic mechanosensitive molecules for the mechanical control of cellular transcription \nMiguel Gonzalez Martin – Cellular and Molecular Mechanobiology\nCells sense mechanical signals in the process of mechanotransduction\, activating pathways that govern cell behavior. However\, it remains a challenge to engineer mechanotransduction pathways in a controllable and predictable manner. Here we aim to engineer a synthetic mechanosensitive transcription factor (msTTA). To this end\, we exploit the force induced changes in nuclear transport\, linking nuclear mechanical perturbations to gene expression. To do so\, we are mechanically tuning the passive and facilitated transport properties of the synthetic msTTA. Through this we aim to recapitulate the localization behavior of endogenous mechanosensitive proteins such as YAP or Twist\, but with a synthetic factor that activates genes of choice in a controlled way. Optimizing our reporter cells\, we have set up a novel screening platform with substrates of different rigidity\, from which we expect to identify highly mechanosensitive TF candidates that function in a tunable manner\, as well as to elucidate which features make a transcription factor mechanosensitive. Overall\, we expect to unlock precise transcriptional control through mechanical forces\, and a state-of-the-art directed evolution platform for msTTAs. With the simplicity of this engineered regulatory module\, we expect to describe the minimal elements of mechano-regulation of gene expression\, as well as enabling the use of mechanotransduction in gene circuits control. This will open the field to use mechanotransduction approaches for complex synthetic biology applications.
URL:https://ibecbarcelona.eu/event/phd-discussion-3/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:PhD Discussions Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20250124T100000
DTEND;TZID=Europe/Madrid:20250124T110000
DTSTAMP:20260425T022730
CREATED:20241122T101514Z
LAST-MODIFIED:20250107T141720Z
UID:121790-1737712800-1737716400@ibecbarcelona.eu
SUMMARY:PhD Discussion: Kristin Fichna and Gian Marco Tuveri
DESCRIPTION:Kristin Fichna – Smart nano-bio-devices \nGian Marco Tuveri –  Molecular bionics \n 
URL:https://ibecbarcelona.eu/event/phd-discussion-kristin-fichna-and-gian-marco/
CATEGORIES:PhD Discussions Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20250411T100000
DTEND;TZID=Europe/Madrid:20250411T110000
DTSTAMP:20260425T022730
CREATED:20250404T103254Z
LAST-MODIFIED:20250404T103254Z
UID:125030-1744365600-1744369200@ibecbarcelona.eu
SUMMARY:PHD Discussion: Miquel Bosch
DESCRIPTION:Force transmission in embryonic-like epithelia\nMiquel Bosch (Integrative Cell and Tissue Dynamics Group) \nDeveloping an adult organism from an embryo is a complex task. Cells need to divide\, differentiate and arrange themselves in complex three-dimensional structures\, a process known as morphogenesis. Apical constriction is a conserved morphogenetic mechanism in the animal kingdom\, but the role of cellular forces during it remains understudied\, especially in the human case. For this reason\, we use human PSCs expressing a novel optogenetic tool\, OptoShroom3. This tool allows to induce apical constriction in vitro on demand\, with precise spatiotemporal control. We study force transmission within the cell layer and to the substrate and find that\, contrary to our intuition\, the apical and basal layer are effectively mechanically decoupled. This decoupling enables long range force transmission in this epiblast-like epithelia. Secondly\, we can study the rheology of the tissue on multiple time and length scales by analyzing the induced deformation field. Since the state of the art for development and disease modelling relies heavily on stem cell systems\, we foresee our study will have broad implications in the field whenever morphogenesis comes at play.
URL:https://ibecbarcelona.eu/event/phd-discussion-miquel-bosch/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:PhD Discussions Session
END:VEVENT
END:VCALENDAR