BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Institute for Bioengineering of Catalonia - ECPv6.15.20//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-WR-CALNAME:Institute for Bioengineering of Catalonia X-ORIGINAL-URL:https://ibecbarcelona.eu X-WR-CALDESC:Events for Institute for Bioengineering of Catalonia REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:Europe/Madrid BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20140330T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20141026T010000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20150329T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20151025T010000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20160327T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20161030T010000 END:STANDARD END:VTIMEZONE BEGIN:VTIMEZONE TZID:UTC BEGIN:STANDARD TZOFFSETFROM:+0000 TZOFFSETTO:+0000 TZNAME:UTC DTSTART:20140101T000000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20151023T100000 DTEND;TZID=Europe/Madrid:20151023T110000 DTSTAMP:20260426T155926 CREATED:20150803T123423Z LAST-MODIFIED:20150803T123423Z UID:95866-1445594400-1445598000@ibecbarcelona.eu SUMMARY:IBEC Seminar: Miquel Bosch Pita DESCRIPTION:The molecular mechanisms of memory persistence: imaging how single synapses learn in real time\nMiquel Bosch Pita\, Nanoprobes and nanoswitches group\, IBEC\nMemories are stored in our brain through the ability of synaptic connections to modify their structure and function in a long-lasting way. However\, nobody has ever observed how these changes occur in a single synapse in real time.\nI will explain how we used a new combination of optical technologies to reveal the molecular remodeling that takes place inside a synapse during the creation of a memory. We used two-photon microscopy to stimulate individual synapses and to visualize protein trafficking in real time. We identified a unique protein that is rapidly and persistently captured in potentiated synapses\, forming a new macromolecule that could serve as a memory tag. We developed a novel photo-marking technique that allowed us to localize the same synapses under both two-photon and electron microscopies. This way we observed how different synaptic structures evolve asynchronously in three temporal phases during synaptic potentiation. URL:https://ibecbarcelona.eu/event/ibec-seminar-miquel-bosch-pita-2/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=UTC:20151022T110000 DTEND;TZID=UTC:20151022T120000 DTSTAMP:20260426T155926 CREATED:20151013T090618Z LAST-MODIFIED:20170801T131050Z UID:19216-1445511600-1445515200@ibecbarcelona.eu SUMMARY:Nanomalaria joint unit seminar: Konstantinos Mitsakakis\, University of Freiburg DESCRIPTION:LabDisk\, a multi-purpose\, multi-target diagnostic platform for patient management and surveillance at the point-of-care\nDr. Konstantinos Mitsakakis\, Hahn-Schickard & IMTEK\, Department of Microsystems Engineering\, University of Freiburg\, Germany\nThe LabDisk is a CD-shaped microfluidic platform with all reagents integrated for on-site sample-to-answer diagnosis of single or multiple infectious diseases stemming from parasites\, bacteria\, viruses\, or co-infections of theirs. Through “composite” diagnosis\, by combining molecular diagnostics and protein biomarker detection\, the LabDisk offers increased reliability in pathogen species identification. Its modular nature enables the creation of a “disc library” for different sample matrices\, and the rapid adaptation to end-users’ requests (endemic needs\, sudden epidemics outbreaks). \nThe presentation will consist of two sections: (1) description of the LabDisk and its operating principle (modularity\, multiplexity\, fully integrated sample preparation); and (2) an overview of the current infectious disease-related applications\, in particular: neonatal sepsis\, respiratory tract infections\, antibiotic resistance\, febrile tropical infections (malaria\, dengue\, pneumonia\, typhoid)\, mosquito/vector control. \nDr. Mitsakakis has been invited by Xavier Fernàndez Busquets\, Head of Nanomalaria Joint Unit URL:https://ibecbarcelona.eu/event/ibec-external-seminar-konstantinos-mitsakakis-university-of-freiburg/ LOCATION:Aula 6\, Faculty of Medicine\, Carrer de Casanova\, 143\, Barcelona CATEGORIES:Joint seminar / workshop / symposium END:VEVENT BEGIN:VEVENT DTSTART;TZID=UTC:20151022T110000 DTEND;TZID=UTC:20151022T120000 DTSTAMP:20260426T155926 CREATED:20151013T090618Z LAST-MODIFIED:20151013T090618Z UID:95870-1445511600-1445515200@ibecbarcelona.eu SUMMARY:Nanomalaria joint unit seminar: Konstantinos Mitsakakis\, University of Freiburg DESCRIPTION:LabDisk\, a multi-purpose\, multi-target diagnostic platform for patient management and surveillance at the point-of-care\nDr. Konstantinos Mitsakakis\, Hahn-Schickard & IMTEK\, Department of Microsystems Engineering\, University of Freiburg\, Germany\nThe LabDisk is a CD-shaped microfluidic platform with all reagents integrated for on-site sample-to-answer diagnosis of single or multiple infectious diseases stemming from parasites\, bacteria\, viruses\, or co-infections of theirs. Through “composite” diagnosis\, by combining molecular diagnostics and protein biomarker detection\, the LabDisk offers increased reliability in pathogen species identification. Its modular nature enables the creation of a “disc library” for different sample matrices\, and the rapid adaptation to end-users’ requests (endemic needs\, sudden epidemics outbreaks). \nThe presentation will consist of two sections: (1) description of the LabDisk and its operating principle (modularity\, multiplexity\, fully integrated sample preparation); and (2) an overview of the current infectious disease-related applications\, in particular: neonatal sepsis\, respiratory tract infections\, antibiotic resistance\, febrile tropical infections (malaria\, dengue\, pneumonia\, typhoid)\, mosquito/vector control. \nDr. Mitsakakis has been invited by Xavier Fernàndez Busquets\, Head of Nanomalaria Joint Unit URL:https://ibecbarcelona.eu/event/ibec-external-seminar-konstantinos-mitsakakis-university-of-freiburg-2/ LOCATION:Aula 6\, Faculty of Medicine\, Carrer de Casanova\, 143\, Barcelona CATEGORIES:Joint seminar / workshop / symposium END:VEVENT BEGIN:VEVENT DTSTART;TZID=UTC:20151021T113000 DTEND;TZID=UTC:20151021T133000 DTSTAMP:20260426T155926 CREATED:20151015T111927Z LAST-MODIFIED:20151015T111927Z UID:95871-1445427000-1445434200@ibecbarcelona.eu SUMMARY:PhD Thesis Defense: Ana Guaman DESCRIPTION:“Multivariate Signal Processing for Quantitative and Qualitative analysis of Ion Mobility Spectrometry applied to Biomedical and Food Applications”\n \nAna Guaman\, Signal and information processing for sensing systems group\nAna will be defending her PhD thesis on Wednesday 21st October at 11:30 in the Sala de grados\, Facultad de Física\, UB. \nEverybody is welcome to attend. \n—\nIf you’re an IBEC PhD student and would like to advertise your PhD defense on the IBEC calendar\, please contact vleigh@ibecbarcelona.eu URL:https://ibecbarcelona.eu/event/phd-thesis-defense-ana-guaman-2/ LOCATION:Sala de Graus Eduard Fontseré\, Martí i Franquès\, 1-11\, Barcelona\, 08028 CATEGORIES:PhD Thesis Defence END:VEVENT BEGIN:VEVENT DTSTART;TZID=UTC:20151021T113000 DTEND;TZID=UTC:20151021T133000 DTSTAMP:20260426T155926 CREATED:20151015T111927Z LAST-MODIFIED:20151015T111927Z UID:19304-1445427000-1445434200@ibecbarcelona.eu SUMMARY:PhD Thesis Defense: Ana Guaman DESCRIPTION:“Multivariate Signal Processing for Quantitative and Qualitative analysis of Ion Mobility Spectrometry applied to Biomedical and Food Applications”\n \nAna Guaman\, Signal and information processing for sensing systems group\nAna will be defending her PhD thesis on Wednesday 21st October at 11:30 in the Sala de grados\, Facultad de Física\, UB. \nEverybody is welcome to attend. \n—\nIf you’re an IBEC PhD student and would like to advertise your PhD defense on the IBEC calendar\, please contact vleigh@ibecbarcelona.eu URL:https://ibecbarcelona.eu/event/phd-thesis-defense-ana-guaman/ LOCATION:Sala de Graus Eduard Fontseré\, Martí i Franquès\, 1-11\, Barcelona\, 08028 CATEGORIES:PhD Thesis Defence END:VEVENT BEGIN:VEVENT DTSTART;TZID=UTC:20151019T100000 DTEND;TZID=UTC:20151019T120000 DTSTAMP:20260426T155926 CREATED:20151006T054804Z LAST-MODIFIED:20151006T054804Z UID:19129-1445248800-1445256000@ibecbarcelona.eu SUMMARY:IBEC Seminar: Cell Imaging Day - Molecular Probes DESCRIPTION:Cell Imaging Day – Molecular Probes\nClara Streiff\, Senior Technical Specialist · Molecular Probes – ThermoFisher Scientific\nSeminar:\n• Marcaje de estructuras celulares en células vivas (Bacmam Cellight)\n• Proliferación celular (Click-iT® EdU)\n• Estrés oxidativo (CellROX®)\n• Fagocitosis (PHrodo)\n• Apoptosis (Cellevent Caspase 3 and 7)\n• Mejorando la señal fluorescente en células vivas y fijadas (ReadyProbes reactivos “ready to use”)\n• Ventajas de la citometría por focalización acústica (Attune®NxT acoustic focusing cytometer) \nAl final del seminario podrás pasar tus muestras en el microscopio EVOS® FL AUTO y prueba nuestros reactivos ReadyProbes de Molecular Probes sin compromiso\, reactivos para imaging que permiten marcar tus células sin necesidad de hacer calculos\, diluciones ni pipetear. URL:https://ibecbarcelona.eu/event/ibec-seminar-cell-imaging-day-molecular-probes/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=UTC:20151019T100000 DTEND;TZID=UTC:20151019T120000 DTSTAMP:20260426T155926 CREATED:20151006T054804Z LAST-MODIFIED:20151006T054804Z UID:95869-1445248800-1445256000@ibecbarcelona.eu SUMMARY:IBEC Seminar: Cell Imaging Day - Molecular Probes DESCRIPTION:Cell Imaging Day – Molecular Probes\nClara Streiff\, Senior Technical Specialist · Molecular Probes – ThermoFisher Scientific\nSeminar:\n• Marcaje de estructuras celulares en células vivas (Bacmam Cellight)\n• Proliferación celular (Click-iT® EdU)\n• Estrés oxidativo (CellROX®)\n• Fagocitosis (PHrodo)\n• Apoptosis (Cellevent Caspase 3 and 7)\n• Mejorando la señal fluorescente en células vivas y fijadas (ReadyProbes reactivos “ready to use”)\n• Ventajas de la citometría por focalización acústica (Attune®NxT acoustic focusing cytometer) \nAl final del seminario podrás pasar tus muestras en el microscopio EVOS® FL AUTO y prueba nuestros reactivos ReadyProbes de Molecular Probes sin compromiso\, reactivos para imaging que permiten marcar tus células sin necesidad de hacer calculos\, diluciones ni pipetear. URL:https://ibecbarcelona.eu/event/ibec-seminar-cell-imaging-day-molecular-probes-2/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20151016T100000 DTEND;TZID=Europe/Madrid:20151016T110000 DTSTAMP:20260426T155926 CREATED:20150713T060412Z LAST-MODIFIED:20150713T060412Z UID:18096-1444989600-1444993200@ibecbarcelona.eu SUMMARY:IBEC Seminar: Lorenzo Albertazzi DESCRIPTION:Nanoscopy for Nanomedicine: looking at nanomaterials in action one molecule at a time\nLorenzo Albertazzi\, IBEC\nThe use of nanomaterials for biomedical purposes such as drug or gene delivery is one of the key applications of nanotechnology. In this framework a variety of materials have been fabricated\, evaluated in cells and in vivo and\, in some cases\, successfully translated into clinical applications. A crucial factor limiting the design of effective nanocarriers is the lack of knowledge about materials-cell interactions that severely limit the rational design of nanosized devices.\nHere I’ll show how advanced optical microscopy techniques can shine a light on nanomaterials behavior in the biological environment\, helping us to understand structure-activity relationships and to design improved and more effective therapeutic devices. In particular I’ll discuss the ability of super resolution microscopy to image with nanometric resolution nanomaterials interactions with target cells. The potential and the applications of the technique will be discussed\, with particular emphasis on the study of self-assembled bio-inspired materials. URL:https://ibecbarcelona.eu/event/ibec-seminar-lorenzo-albertazzi/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20151016T100000 DTEND;TZID=Europe/Madrid:20151016T110000 DTSTAMP:20260426T155926 CREATED:20150713T060412Z LAST-MODIFIED:20150713T060412Z UID:95862-1444989600-1444993200@ibecbarcelona.eu SUMMARY:IBEC Seminar: Lorenzo Albertazzi DESCRIPTION:Nanoscopy for Nanomedicine: looking at nanomaterials in action one molecule at a time\nLorenzo Albertazzi\, IBEC\nThe use of nanomaterials for biomedical purposes such as drug or gene delivery is one of the key applications of nanotechnology. In this framework a variety of materials have been fabricated\, evaluated in cells and in vivo and\, in some cases\, successfully translated into clinical applications. A crucial factor limiting the design of effective nanocarriers is the lack of knowledge about materials-cell interactions that severely limit the rational design of nanosized devices.\nHere I’ll show how advanced optical microscopy techniques can shine a light on nanomaterials behavior in the biological environment\, helping us to understand structure-activity relationships and to design improved and more effective therapeutic devices. In particular I’ll discuss the ability of super resolution microscopy to image with nanometric resolution nanomaterials interactions with target cells. The potential and the applications of the technique will be discussed\, with particular emphasis on the study of self-assembled bio-inspired materials. URL:https://ibecbarcelona.eu/event/ibec-seminar-lorenzo-albertazzi-2/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20151001T090000 DTEND;TZID=Europe/Madrid:20151002T123000 DTSTAMP:20260426T155926 CREATED:20150901T133610Z LAST-MODIFIED:20170801T131104Z UID:18643-1443690000-1443789000@ibecbarcelona.eu SUMMARY:B·Debate: Future Tools for Biomedical Research: in vitro\, in silico and in vivo disease modeling DESCRIPTION:The increasing costs of biomedical research and drug discovery and the continually rising numbers of compound failures provoke an urgent need for novel tools for basic research and preclinical testing of drugs. \nThe cross-breeding of nanotechnologies\, life and computational sciences is harnessing enabling technologies for drug discovery\, development\, toxicity testing and disease modeling. These advances can move in vitro cell and tissue cultures beyond the current state-of-the-art\, which poorly reflect patient physiology\, and create “in vivo human-like” platforms that allow cheaper and efficient drug and toxicity assays. \nAt the same time\, important efforts are being made to create improved animal and computational models to better mimic human physiology in health and disease. \nUnder this framework\, the B·Debate “Future Tools for Biomedical Research: In Vitro\, In Silico and In Vivo Disease Modeling”\, coorganized by B·Debate and  IBEC\, is an opportunity to debate with experts and professionals of the field to review experiences and best practices and to identify and address barriers in the development and adoption of advanced methods for disease modeling\, with a potential to revolutionize preclinical research in particular\, and the validation and commercialization of new therapies and diagnostics at large. \nVisit the website for more details. URL:https://ibecbarcelona.eu/event/b%c2%b7debate-future-tools-for-biomedical-research-in-vitro-in-silico-and-in-vivo-disease-modeling/ LOCATION:CosmoCaixa Barcelona\, Carrer d'Isaac Newton\, 08022 Barcelona\, Spain CATEGORIES:IBEC Symposium / Conference / Congress / Workshop END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20151001T090000 DTEND;TZID=Europe/Madrid:20151002T123000 DTSTAMP:20260426T155926 CREATED:20150901T133610Z LAST-MODIFIED:20150901T133610Z UID:95867-1443690000-1443789000@ibecbarcelona.eu SUMMARY:B·Debate: Future Tools for Biomedical Research: in vitro\, in silico and in vivo disease modeling DESCRIPTION:The increasing costs of biomedical research and drug discovery and the continually rising numbers of compound failures provoke an urgent need for novel tools for basic research and preclinical testing of drugs. \nThe cross-breeding of nanotechnologies\, life and computational sciences is harnessing enabling technologies for drug discovery\, development\, toxicity testing and disease modeling. These advances can move in vitro cell and tissue cultures beyond the current state-of-the-art\, which poorly reflect patient physiology\, and create “in vivo human-like” platforms that allow cheaper and efficient drug and toxicity assays. \nAt the same time\, important efforts are being made to create improved animal and computational models to better mimic human physiology in health and disease. \nUnder this framework\, the B·Debate “Future Tools for Biomedical Research: In Vitro\, In Silico and In Vivo Disease Modeling”\, coorganized by B·Debate and  IBEC\, is an opportunity to debate with experts and professionals of the field to review experiences and best practices and to identify and address barriers in the development and adoption of advanced methods for disease modeling\, with a potential to revolutionize preclinical research in particular\, and the validation and commercialization of new therapies and diagnostics at large. \nVisit the website for more details. URL:https://ibecbarcelona.eu/event/b%c2%b7debate-future-tools-for-biomedical-research-in-vitro-in-silico-and-in-vivo-disease-modeling-2/ LOCATION:CosmoCaixa Barcelona\, Carrer d'Isaac Newton\, 08022 Barcelona\, Spain CATEGORIES:IBEC Symposium / Conference / Congress / Workshop END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150930T080000 DTEND;TZID=Europe/Madrid:20150930T180000 DTSTAMP:20260426T155926 CREATED:20150629T071347Z LAST-MODIFIED:20150803T123238Z UID:17665-1443600000-1443636000@ibecbarcelona.eu SUMMARY:8th IBEC Symposium DESCRIPTION:8th IBEC Symposium: Bioengineering for Regenerative Therapies\nWednesday 30th September 2015\nPlease save the date for the 8th IBEC Symposium on Bioengineering for Regenerative Therapies\, which will take place on Wednesday 30th September 2015. \nThis year\, the IBEC Symposium will focus on one of our three areas of applications for bioengineering\, Regenerative Therapies\, and will bring together high-profile international experts in our fields of expertise. It provides an open forum for interdisciplinary discussions and networking\, benefitting young researchers and established scientists alike. \nConfirmed speakers this year include:\nGiorgio Scita\, Associate Professor of General Pathology at the Department of Health Sciences\, University of Milan.\nManuel Salmeron\, Chair of Biomedical Engineering\, University of Glasgow\nRon Mckay\, Director for Basic Sciences\, Lieber Institute for Brain Development\, Baltimore\nJosep Samitier\, IBEC \nEveryone is welcome to submit abstracts for the posters and flash presentations sessions by Thursday 16th July 2015. Please use this template. \nWe look forward to welcoming you to our symposium in September.\n  \nUseful dates:\nDeadline for abstracts: 16th July 2015\nNotification of acceptance: 8th September 2015\nhttps://ibecbarcelona.eu/events/Symposium2015 URL:https://ibecbarcelona.eu/event/8th-ibec-symposium/ LOCATION:AXA Auditorium\, L'illa Diagonal\, Av. Diagonal 547 \, Barcelona\, 08029 CATEGORIES:IBEC Symposium / Conference / Congress / Workshop END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150930T080000 DTEND;TZID=Europe/Madrid:20150930T180000 DTSTAMP:20260426T155926 CREATED:20150629T071347Z LAST-MODIFIED:20150629T071347Z UID:95858-1443600000-1443636000@ibecbarcelona.eu SUMMARY:8th IBEC Symposium DESCRIPTION:8th IBEC Symposium: Bioengineering for Regenerative Therapies\nWednesday 30th September 2015\nPlease save the date for the 8th IBEC Symposium on Bioengineering for Regenerative Therapies\, which will take place on Wednesday 30th September 2015. \nThis year\, the IBEC Symposium will focus on one of our three areas of applications for bioengineering\, Regenerative Therapies\, and will bring together high-profile international experts in our fields of expertise. It provides an open forum for interdisciplinary discussions and networking\, benefitting young researchers and established scientists alike. \nConfirmed speakers this year include:\nGiorgio Scita\, Associate Professor of General Pathology at the Department of Health Sciences\, University of Milan.\nManuel Salmeron\, Chair of Biomedical Engineering\, University of Glasgow\nRon Mckay\, Director for Basic Sciences\, Lieber Institute for Brain Development\, Baltimore\nJosep Samitier\, IBEC \nEveryone is welcome to submit abstracts for the posters and flash presentations sessions by Thursday 16th July 2015. Please use this template. \nWe look forward to welcoming you to our symposium in September.\n  \nUseful dates:\nDeadline for abstracts: 16th July 2015\nNotification of acceptance: 8th September 2015\nhttp://ibecbarcelona.eu/events/Symposium2015 URL:https://ibecbarcelona.eu/event/8th-ibec-symposium-2/ LOCATION:AXA Auditorium\, L'illa Diagonal\, Av. Diagonal 547 \, Barcelona\, 08029 CATEGORIES:IBEC Symposium / Conference / Congress / Workshop END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150922T000000 DTEND;TZID=Europe/Madrid:20150922T130000 DTSTAMP:20260426T155926 CREATED:20150918T102346Z LAST-MODIFIED:20150918T102346Z UID:18953-1442880000-1442926800@ibecbarcelona.eu SUMMARY:IBEC Seminar: Albert Folch DESCRIPTION:Print-and-Play Microfluidics\nAlbert Folch\, Associate Professor\, University of Washington\nBiologists and clinicians typically do not have access to microfluidic technology because they do not have the engineering expertise or equipment required to fabricate and/or operate microfluidic devices. Furthermore\, the present commercialization path for microfluidic devices is usually restricted to high-volume applications in order to recover the large investment needed to develop the plastic molding processes. We are developing microfluidic devices through stereolithography\, a form of 3D printing\, in order to make microfluidic technology readily available via the web to biomedical scientists. Our lab presently focuses on developing 3D-printable microdevices that facilitate the advancement of basic neuroscience and translational cancer applications. The lab’s long-term mission is to make microfluidic devices as easy to use as smartphones and make them easily available to clinicians in order to enable novel cancer diagnostics and therapies. URL:https://ibecbarcelona.eu/event/ibec-seminar-albert-folch/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150922T000000 DTEND;TZID=Europe/Madrid:20150922T130000 DTSTAMP:20260426T155926 CREATED:20150918T102346Z LAST-MODIFIED:20150918T102346Z UID:95868-1442880000-1442926800@ibecbarcelona.eu SUMMARY:IBEC Seminar: Albert Folch DESCRIPTION:Print-and-Play Microfluidics\nAlbert Folch\, Associate Professor\, University of Washington\nBiologists and clinicians typically do not have access to microfluidic technology because they do not have the engineering expertise or equipment required to fabricate and/or operate microfluidic devices. Furthermore\, the present commercialization path for microfluidic devices is usually restricted to high-volume applications in order to recover the large investment needed to develop the plastic molding processes. We are developing microfluidic devices through stereolithography\, a form of 3D printing\, in order to make microfluidic technology readily available via the web to biomedical scientists. Our lab presently focuses on developing 3D-printable microdevices that facilitate the advancement of basic neuroscience and translational cancer applications. The lab’s long-term mission is to make microfluidic devices as easy to use as smartphones and make them easily available to clinicians in order to enable novel cancer diagnostics and therapies. URL:https://ibecbarcelona.eu/event/ibec-seminar-albert-folch-2/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150918T100000 DTEND;TZID=Europe/Madrid:20150918T110000 DTSTAMP:20260426T155926 CREATED:20150629T072320Z LAST-MODIFIED:20150629T072320Z UID:17667-1442570400-1442574000@ibecbarcelona.eu SUMMARY:IBEC Seminar: Marc Martí-Renom DESCRIPTION:Structure determination of genomes and genomic domains by satisfaction of spatial restraints\nMarc Martí-Renom\, ICREA Research Professor / CNAG / CRG\nThe genome three-dimensional (3D) organization plays important\, yet poorly understood roles in gene regulation. Chromosomes assume multiple distinct conformations in relation to the expression status of resident genes and undergo dramatic alterations in higher order structure through the cell cycle. Despite advances in microscopy\, a general technique to determine the 3D conformation of chromatin has been lacking. We developed a new method for the determination of the 3D conformation of chromatin domains in the interphase nucleus\, which combines 3C-based experiments with the computational Integrative Modeling Platform (IMP). The general approach of our method\, which has been applied to study the 3D conformation of the alpha-globin domain in the human genome [1]\, the Caulobacter crescentus whole genome [2]\, and the dynamic response of Topologically Associating Domains (TADs) to hormone treatment in breast cancer cell lines [3]\, opens the field for comprehensive studies of the 3D conformation of chromosomal domains and contributes to a more complete characterization of genome regulation.\n[1] D. Baù et al. Nat Struct Mol Biol (2011) 18:107.\n[2] M.A. Umbarger\, et al. Molecular Cell (2011) 44:252\n[3] Le Dily\, et al. Genes & Dev (2014) 28:2151 URL:https://ibecbarcelona.eu/event/ibec-seminar-marc-marti-renom/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150918T100000 DTEND;TZID=Europe/Madrid:20150918T110000 DTSTAMP:20260426T155926 CREATED:20150629T072320Z LAST-MODIFIED:20150629T072320Z UID:95859-1442570400-1442574000@ibecbarcelona.eu SUMMARY:IBEC Seminar: Marc Martí-Renom DESCRIPTION:Structure determination of genomes and genomic domains by satisfaction of spatial restraints\nMarc Martí-Renom\, ICREA Research Professor / CNAG / CRG\nThe genome three-dimensional (3D) organization plays important\, yet poorly understood roles in gene regulation. Chromosomes assume multiple distinct conformations in relation to the expression status of resident genes and undergo dramatic alterations in higher order structure through the cell cycle. Despite advances in microscopy\, a general technique to determine the 3D conformation of chromatin has been lacking. We developed a new method for the determination of the 3D conformation of chromatin domains in the interphase nucleus\, which combines 3C-based experiments with the computational Integrative Modeling Platform (IMP). The general approach of our method\, which has been applied to study the 3D conformation of the alpha-globin domain in the human genome [1]\, the Caulobacter crescentus whole genome [2]\, and the dynamic response of Topologically Associating Domains (TADs) to hormone treatment in breast cancer cell lines [3]\, opens the field for comprehensive studies of the 3D conformation of chromosomal domains and contributes to a more complete characterization of genome regulation.\n[1] D. Baù et al. Nat Struct Mol Biol (2011) 18:107.\n[2] M.A. Umbarger\, et al. Molecular Cell (2011) 44:252\n[3] Le Dily\, et al. Genes & Dev (2014) 28:2151 URL:https://ibecbarcelona.eu/event/ibec-seminar-marc-marti-renom-2/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150917T100000 DTEND;TZID=Europe/Madrid:20150917T110000 DTSTAMP:20260426T155926 CREATED:20150803T122810Z LAST-MODIFIED:20150803T122810Z UID:95865-1442484000-1442487600@ibecbarcelona.eu SUMMARY:IBEC Seminar: Richard Reilly DESCRIPTION:All a question of Timing: Sensory processing in Dystonia and Parkinson’s Disease\nProfessor Richard Reilly\, Trinity Centre for Bioengineering · Trinity College Dublin\nThere are many challenges in the diagnosis and management of neurological disorders. Neural Engineering can help address some of these by the development of novel engineering\, computational and experimental methods to help understand the pathogenesis of neurological disorders. This talk will detail results from recent neural engineering studies into understanding cervical dystonia and Parkinson’s disease. \nWhile the pathogenesis of cervical dystonia remains unknown\, recent animal and clinical experimental studies have indicated its probable mechanisms. Human movement involves a complex series of coordinated musculoskeletal but also neural processes. A breakdown in any of these processes can result in irregular movement. The temporal discrimination threshold is the shortest time interval at which two sensory stimuli presented sequentially are detected as asynchronous by the observer. Studies in our group and that of others have shown that abnormal temporal discrimination is a mediational endophenotype of cervical dystonia and informs new concepts of disease pathogenesis. Our hypothesis is that both abnormal temporal discrimination and cervical dystonia are due to a disorder of the midbrain network for covert attentional orienting caused by reduced gamma-aminobutyric acid inhibition\, resulting from\, in turn\, from as yet undetermined\, genetic mutations. Such disinhibition is a) subclinically manifested by abnormal temporal discrimination due to prolonged duration firing of the visual sensory neurons in the superficial laminae of the superior colliculus\, b) clinically manifested by cervical dystonia due to disinhibited burst activity of the cephalomotor neurons of the intermediate and deep laminae of the superior colliculus. Abnormal temporal discrimination in unaffected first-degree relatives of patients with cervical dystonia represents a subclinical manifestation of defective gamma-aminobutyric acid activity both within the superior colliculus and from the substantia nigra pars reticulata. This talk will review some our recent experiments addressing this hypothesis. \nSensory and perceptual disturbances are common in Parkinson’s disease. Subtle deficits of the sensory system\, often not detected by routine examination\, occur in people with Parkinson’s disease. From simple anosmia and impaired kinesthetic perception\, to more complex visual hallucinations and spatiotemporal perceptual abnormalities\, altered sensory processing is found across multiple modalities. Of note\, integration of multiple environmental sensory inputs is crucial for a refined but complex goal-directed motor output (e.g. locomotion through a crowded environment). There is increasing evidence that these sensory deficits contribute to the pathophysiology of some of the abnormal motor features of Parkinson’s disease. This talk will review some of our recent experiments to probe multisensory deficits in Parkinson’s disease and introduce one intervention developed around sensory and cognitive processing. URL:https://ibecbarcelona.eu/event/ibec-seminar-richard-reilly-2/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150917T100000 DTEND;TZID=Europe/Madrid:20150917T110000 DTSTAMP:20260426T155926 CREATED:20150803T122810Z LAST-MODIFIED:20150803T122810Z UID:18430-1442484000-1442487600@ibecbarcelona.eu SUMMARY:IBEC Seminar: Richard Reilly DESCRIPTION:All a question of Timing: Sensory processing in Dystonia and Parkinson’s Disease\nProfessor Richard Reilly\, Trinity Centre for Bioengineering · Trinity College Dublin\nThere are many challenges in the diagnosis and management of neurological disorders. Neural Engineering can help address some of these by the development of novel engineering\, computational and experimental methods to help understand the pathogenesis of neurological disorders. This talk will detail results from recent neural engineering studies into understanding cervical dystonia and Parkinson’s disease. \nWhile the pathogenesis of cervical dystonia remains unknown\, recent animal and clinical experimental studies have indicated its probable mechanisms. Human movement involves a complex series of coordinated musculoskeletal but also neural processes. A breakdown in any of these processes can result in irregular movement. The temporal discrimination threshold is the shortest time interval at which two sensory stimuli presented sequentially are detected as asynchronous by the observer. Studies in our group and that of others have shown that abnormal temporal discrimination is a mediational endophenotype of cervical dystonia and informs new concepts of disease pathogenesis. Our hypothesis is that both abnormal temporal discrimination and cervical dystonia are due to a disorder of the midbrain network for covert attentional orienting caused by reduced gamma-aminobutyric acid inhibition\, resulting from\, in turn\, from as yet undetermined\, genetic mutations. Such disinhibition is a) subclinically manifested by abnormal temporal discrimination due to prolonged duration firing of the visual sensory neurons in the superficial laminae of the superior colliculus\, b) clinically manifested by cervical dystonia due to disinhibited burst activity of the cephalomotor neurons of the intermediate and deep laminae of the superior colliculus. Abnormal temporal discrimination in unaffected first-degree relatives of patients with cervical dystonia represents a subclinical manifestation of defective gamma-aminobutyric acid activity both within the superior colliculus and from the substantia nigra pars reticulata. This talk will review some our recent experiments addressing this hypothesis. \nSensory and perceptual disturbances are common in Parkinson’s disease. Subtle deficits of the sensory system\, often not detected by routine examination\, occur in people with Parkinson’s disease. From simple anosmia and impaired kinesthetic perception\, to more complex visual hallucinations and spatiotemporal perceptual abnormalities\, altered sensory processing is found across multiple modalities. Of note\, integration of multiple environmental sensory inputs is crucial for a refined but complex goal-directed motor output (e.g. locomotion through a crowded environment). There is increasing evidence that these sensory deficits contribute to the pathophysiology of some of the abnormal motor features of Parkinson’s disease. This talk will review some of our recent experiments to probe multisensory deficits in Parkinson’s disease and introduce one intervention developed around sensory and cognitive processing. URL:https://ibecbarcelona.eu/event/ibec-seminar-richard-reilly/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150724T100000 DTEND;TZID=Europe/Madrid:20150724T110000 DTSTAMP:20260426T155926 CREATED:20150720T092247Z LAST-MODIFIED:20150720T102616Z UID:18148-1437732000-1437735600@ibecbarcelona.eu SUMMARY:IBEC Seminar: Dr. François St. Pierre DESCRIPTION:Imaging electrical activity in vivo with ultrafast protein sensors \nDr. François St. Pierre\, Department of Neuroscience\, Baylor College of Medicine / \nDepartment of Electrical and Computer Engineering\, Rice University\nImaging of rapid brain electrical activity has been on the wish list of neurobiologists for many years and has received renewed attention with the launch of the BRAIN initiative by the White House in the U.S.A. In particular\, neuroscientists have long sought voltage sensors based on proteins to reveal brain activity in genetically defined neuronal circuits. I will present novel protein voltage sensors that leverage optimized parts and creative new designs to report neural activity with unprecedented temporal resolution in vitro\, in brain slices and in vivo. Importantly\, these synthetic sensors report neural activity at the millisecond timescale over which key information processing functions are thought to take place. I will show how these new optical tools enable us to follow neural information processing in the fly visual system with subcellular resolution. I will also present our recent success at monitoring spontaneous electrical activity in stem cell-derived cardiomyocytes. URL:https://ibecbarcelona.eu/event/ibec-seminar-dr-francois-st-pierre/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150724T100000 DTEND;TZID=Europe/Madrid:20150724T110000 DTSTAMP:20260426T155926 CREATED:20150720T092247Z LAST-MODIFIED:20150720T092247Z UID:95864-1437732000-1437735600@ibecbarcelona.eu SUMMARY:IBEC Seminar: Dr. François St. Pierre DESCRIPTION:Imaging electrical activity in vivo with ultrafast protein sensors \nDr. François St. Pierre\, Department of Neuroscience\, Baylor College of Medicine / \nDepartment of Electrical and Computer Engineering\, Rice University\nImaging of rapid brain electrical activity has been on the wish list of neurobiologists for many years and has received renewed attention with the launch of the BRAIN initiative by the White House in the U.S.A. In particular\, neuroscientists have long sought voltage sensors based on proteins to reveal brain activity in genetically defined neuronal circuits. I will present novel protein voltage sensors that leverage optimized parts and creative new designs to report neural activity with unprecedented temporal resolution in vitro\, in brain slices and in vivo. Importantly\, these synthetic sensors report neural activity at the millisecond timescale over which key information processing functions are thought to take place. I will show how these new optical tools enable us to follow neural information processing in the fly visual system with subcellular resolution. I will also present our recent success at monitoring spontaneous electrical activity in stem cell-derived cardiomyocytes. URL:https://ibecbarcelona.eu/event/ibec-seminar-dr-francois-st-pierre-2/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150721T110000 DTEND;TZID=Europe/Madrid:20150721T130000 DTSTAMP:20260426T155926 CREATED:20150714T085454Z LAST-MODIFIED:20150714T085454Z UID:95863-1437476400-1437483600@ibecbarcelona.eu SUMMARY:PhD Thesis Defense: Erola Pairo DESCRIPTION:“Detection of transcription factor binding sites by multivariate signal processing”\n \nErola Pairo\, Signal and information processing for sensing systems group\nErola will be defending her PhD thesis on Tuesday 21st July at 11:00 in the Eduard Fontsere room at the Faculty of Physics. \nEverybody is welcome to attend. \n—\nIf you’re an IBEC PhD student and would like to advertise your PhD defense on the IBEC calendar\, please contact vleigh@ibecbarcelona.eu URL:https://ibecbarcelona.eu/event/phd-thesis-defense-erola-pairo-2/ LOCATION:Sala de Graus Eduard Fontseré\, Martí i Franquès\, 1-11\, Barcelona\, 08028 CATEGORIES:PhD Thesis Defence END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150721T110000 DTEND;TZID=Europe/Madrid:20150721T130000 DTSTAMP:20260426T155926 CREATED:20150714T085454Z LAST-MODIFIED:20150714T085823Z UID:18116-1437476400-1437483600@ibecbarcelona.eu SUMMARY:PhD Thesis Defense: Erola Pairo DESCRIPTION:“Detection of transcription factor binding sites by multivariate signal processing”\n \nErola Pairo\, Signal and information processing for sensing systems group\nErola will be defending her PhD thesis on Tuesday 21st July at 11:00 in the Eduard Fontsere room at the Faculty of Physics. \nEverybody is welcome to attend. \n—\nIf you’re an IBEC PhD student and would like to advertise your PhD defense on the IBEC calendar\, please contact vleigh@ibecbarcelona.eu URL:https://ibecbarcelona.eu/event/phd-thesis-defense-erola-pairo/ LOCATION:Sala de Graus Eduard Fontseré\, Martí i Franquès\, 1-11\, Barcelona\, 08028 CATEGORIES:PhD Thesis Defence END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150717T150000 DTEND;TZID=Europe/Madrid:20150717T170000 DTSTAMP:20260426T155926 CREATED:20150713T053848Z LAST-MODIFIED:20150713T053848Z UID:95861-1437145200-1437152400@ibecbarcelona.eu SUMMARY:PhD Thesis Defense: Carlos Ruiz DESCRIPTION:“A computational study of intervertebral disc degeneration in relation to changes in regional tissue composition and disc nutrition”\n \nCarlos Ruiz Wills\, Biomechanics & Mechanobiology group\nCarles will be defending his PhD thesis on Friday 17th July at 15:00 in the Aula Capella\, Facultad de Ingeniería Industrial (ETSEIB)\, Av. Diagonal 647. \nEverybody is welcome to attend. \n—\nIf you’re an IBEC PhD student and would like to advertise your PhD defense on the IBEC calendar\, please contact vleigh@ibecbarcelona.eu URL:https://ibecbarcelona.eu/event/phd-thesis-defense-carlos-ruiz-2/ LOCATION:Aula Capella\, Facultad de Ingeniería Industrial (ETSEIB)\, Av. Diagonal 647\, Barcelona\, Spain CATEGORIES:PhD Thesis Defence END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150717T150000 DTEND;TZID=Europe/Madrid:20150717T170000 DTSTAMP:20260426T155926 CREATED:20150713T053848Z LAST-MODIFIED:20150714T085909Z UID:18094-1437145200-1437152400@ibecbarcelona.eu SUMMARY:PhD Thesis Defense: Carlos Ruiz DESCRIPTION:“A computational study of intervertebral disc degeneration in relation to changes in regional tissue composition and disc nutrition”\n \nCarlos Ruiz Wills\, Biomechanics & Mechanobiology group\nCarles will be defending his PhD thesis on Friday 17th July at 15:00 in the Aula Capella\, Facultad de Ingeniería Industrial (ETSEIB)\, Av. Diagonal 647. \nEverybody is welcome to attend. \n—\nIf you’re an IBEC PhD student and would like to advertise your PhD defense on the IBEC calendar\, please contact vleigh@ibecbarcelona.eu URL:https://ibecbarcelona.eu/event/phd-thesis-defense-carlos-ruiz/ LOCATION:Aula Capella\, Facultad de Ingeniería Industrial (ETSEIB)\, Av. Diagonal 647\, Barcelona\, Spain CATEGORIES:PhD Thesis Defence END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150710T100000 DTEND;TZID=Europe/Madrid:20150710T110000 DTSTAMP:20260426T155926 CREATED:20150527T073448Z LAST-MODIFIED:20150527T073448Z UID:16868-1436522400-1436526000@ibecbarcelona.eu SUMMARY:PhD Discussions Session: Verónica Hortigüela & Anna Crespo DESCRIPTION:Developing a platform for receptor clustering studies\nVerónica Hortigüela\, Biomimetic systems for cell engineering group\nReceptors are signaling units that usually require interactions and associations with other molecules in complexes to trigger a signaling pathway. This process is known as receptor clustering and comes typically along with a simultaneous ligand clustering underneath the cell membrane. We have developed a strategy to precisely control the ligand distribution on a substrate at the nanoscale to study in detail receptor clustering processes. Herein we present a tunable platform based on self-assembled di-block copolymers that tend to segregate into nanostructures. Di-block copolymers are confined to a thin film providing a template for ligand patterning. \n  \nRibonucleotide Reductase anaerobic enzymes are essential for biofilm formation of Pseudomonas aeruginosa\nAnna Crespo\, Bacterial infections: antimicrobial therapies group\nMost chronic infections in humans are caused by communities of microorganisms living in organized structures\, known as biofilms. Biofilm-related infections\, such as pneumonia (in patients suffering for cystic fibrosis or chronic obstructive pulmonary disease –COPD-) and catheter-associated infections\, affect millions of people in the developed world. \nCell clusters in biofilms are characterized by presenting\, in its extracellular polymeric matrix\, gradients of oxygen\, nutrients and metabolic waste products. The so-formed chemical heterogeneity (e.g.\, the presence of anoxic areas) leads to the appearance of different metabolic activities. \nPseudomonas aeruginosa has been used as a model bacterium for biofilm research; it causes biofilm-related chronic infections and presents high metabolic versatility\, together with an extreme antibiotic resistance. \nIn this work we have studied P. aeruginosa\, focusing in an essential enzyme for its growth\, Ribonucleotide Reductase (RNR). Ribonucleotide Reductases catalyse the reduction of ribonucleotides (NTPs) to deoxyribonucleotides (dNTPs)\, thereby providing the building blocks for DNA synthesis. There are three different RNR classes\, named class I\, class II and class III\, which are\, respectively\, oxygen-dependent\, oxygen-independent and oxygen-sensitive. The last two ones\, essential for anaerobic growth in Pseudomonas aeruginosa\, have been proved to be necessary for biofilm formation\, and therefore putative targets for new therapies against P. aeruginosa chronic infections. URL:https://ibecbarcelona.eu/event/phd-discussions-session-veronica-hortiguela-anna-crespo/ CATEGORIES:PhD Discussions Session END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150710T100000 DTEND;TZID=Europe/Madrid:20150710T110000 DTSTAMP:20260426T155926 CREATED:20150527T073448Z LAST-MODIFIED:20150527T073448Z UID:95855-1436522400-1436526000@ibecbarcelona.eu SUMMARY:PhD Discussions Session: Verónica Hortigüela & Anna Crespo DESCRIPTION:Developing a platform for receptor clustering studies\nVerónica Hortigüela\, Biomimetic systems for cell engineering group\nReceptors are signaling units that usually require interactions and associations with other molecules in complexes to trigger a signaling pathway. This process is known as receptor clustering and comes typically along with a simultaneous ligand clustering underneath the cell membrane. We have developed a strategy to precisely control the ligand distribution on a substrate at the nanoscale to study in detail receptor clustering processes. Herein we present a tunable platform based on self-assembled di-block copolymers that tend to segregate into nanostructures. Di-block copolymers are confined to a thin film providing a template for ligand patterning. \n  \nRibonucleotide Reductase anaerobic enzymes are essential for biofilm formation of Pseudomonas aeruginosa\nAnna Crespo\, Bacterial infections: antimicrobial therapies group\nMost chronic infections in humans are caused by communities of microorganisms living in organized structures\, known as biofilms. Biofilm-related infections\, such as pneumonia (in patients suffering for cystic fibrosis or chronic obstructive pulmonary disease –COPD-) and catheter-associated infections\, affect millions of people in the developed world. \nCell clusters in biofilms are characterized by presenting\, in its extracellular polymeric matrix\, gradients of oxygen\, nutrients and metabolic waste products. The so-formed chemical heterogeneity (e.g.\, the presence of anoxic areas) leads to the appearance of different metabolic activities. \nPseudomonas aeruginosa has been used as a model bacterium for biofilm research; it causes biofilm-related chronic infections and presents high metabolic versatility\, together with an extreme antibiotic resistance. \nIn this work we have studied P. aeruginosa\, focusing in an essential enzyme for its growth\, Ribonucleotide Reductase (RNR). Ribonucleotide Reductases catalyse the reduction of ribonucleotides (NTPs) to deoxyribonucleotides (dNTPs)\, thereby providing the building blocks for DNA synthesis. There are three different RNR classes\, named class I\, class II and class III\, which are\, respectively\, oxygen-dependent\, oxygen-independent and oxygen-sensitive. The last two ones\, essential for anaerobic growth in Pseudomonas aeruginosa\, have been proved to be necessary for biofilm formation\, and therefore putative targets for new therapies against P. aeruginosa chronic infections. URL:https://ibecbarcelona.eu/event/phd-discussions-session-veronica-hortiguela-anna-crespo-2/ CATEGORIES:PhD Discussions Session END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150706T150000 DTEND;TZID=Europe/Madrid:20150706T160000 DTSTAMP:20260426T155926 CREATED:20150701T122222Z LAST-MODIFIED:20150701T122253Z UID:17897-1436194800-1436198400@ibecbarcelona.eu SUMMARY:IBEC Seminar: Prof. Saman K. Halgamuge DESCRIPTION:Big Data Analytics in Metagenomics\nSaman K. Halgamuge\, Melbourne School of Engineering\, University of Melbourne\, Australia\nIn collaboration with researchers in Academia Sinica and Metabolomics Australia/Department of Botany at Melbourne\, we have been working in two areas of Bioinformatics: Metabolomics focusing on microbes and Metagenomics focusing on plants. Profiling large sets of data resulted from technological advances in whole genome sequencing and MALDI Imaging type technologies that can reveal vital information about the environment and plants\, which is our major or primary source of food on Earth. Recently we have demonstrated considerable success in using unsupervised clustering techniques to analyse genetic and metabolomic data. This includes analysis of viral quasi species\, metabolomics and microbial metagenomes. \nSome microbes in the environment appear to look very similar and found “living together” in communities in non-separable ways\, making them harder to culture in a lab. To make matters worst\, considering our belief\, if it is correct at all\, that we know only about up to 2% of the microbes around us. When we know only so little about the data labels\, in this case\, about the identity of the species. It is even more challenging to recognise patterns associated with the genomes of the quasispecies (a set of genetically related but non-identical viral mutant types\, which can also be referred to as strains\,) that are able to co-exist within the host. Uncovering information about quasi-species populations of microbes significantly benefits the study of disease progression\, antiviral drug design\, vaccine design and viral pathogenesis. We present a new analysis pipeline called ViQuaS for viral quasispecies spectrum reconstruction using short next-generation sequencing reads. ViQuaS is based on a novel reference-assisted de novo assembly algorithm for constructing local haplotypes. URL:https://ibecbarcelona.eu/event/ibec-seminar-prof-saman-k-halgamuge/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150706T150000 DTEND;TZID=Europe/Madrid:20150706T160000 DTSTAMP:20260426T155926 CREATED:20150701T122222Z LAST-MODIFIED:20150701T122222Z UID:95860-1436194800-1436198400@ibecbarcelona.eu SUMMARY:IBEC Seminar: Prof. Saman K. Halgamuge DESCRIPTION:Big Data Analytics in Metagenomics\nSaman K. Halgamuge\, Melbourne School of Engineering\, University of Melbourne\, Australia\nIn collaboration with researchers in Academia Sinica and Metabolomics Australia/Department of Botany at Melbourne\, we have been working in two areas of Bioinformatics: Metabolomics focusing on microbes and Metagenomics focusing on plants. Profiling large sets of data resulted from technological advances in whole genome sequencing and MALDI Imaging type technologies that can reveal vital information about the environment and plants\, which is our major or primary source of food on Earth. Recently we have demonstrated considerable success in using unsupervised clustering techniques to analyse genetic and metabolomic data. This includes analysis of viral quasi species\, metabolomics and microbial metagenomes. \nSome microbes in the environment appear to look very similar and found “living together” in communities in non-separable ways\, making them harder to culture in a lab. To make matters worst\, considering our belief\, if it is correct at all\, that we know only about up to 2% of the microbes around us. When we know only so little about the data labels\, in this case\, about the identity of the species. It is even more challenging to recognise patterns associated with the genomes of the quasispecies (a set of genetically related but non-identical viral mutant types\, which can also be referred to as strains\,) that are able to co-exist within the host. Uncovering information about quasi-species populations of microbes significantly benefits the study of disease progression\, antiviral drug design\, vaccine design and viral pathogenesis. We present a new analysis pipeline called ViQuaS for viral quasispecies spectrum reconstruction using short next-generation sequencing reads. ViQuaS is based on a novel reference-assisted de novo assembly algorithm for constructing local haplotypes. URL:https://ibecbarcelona.eu/event/ibec-seminar-prof-saman-k-halgamuge-2/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150626T100000 DTEND;TZID=Europe/Madrid:20150626T110000 DTSTAMP:20260426T155926 CREATED:20150527T073121Z LAST-MODIFIED:20150527T073212Z UID:16867-1435312800-1435316400@ibecbarcelona.eu SUMMARY:Phd Discussions Complementary Skills Session: Elisabeth Pain\, Science Careers DESCRIPTION:Planning for an Academic Career: A postdoc and beyond\n \nElisabeth Pain\, Contributing Editor for Science Careers\, Europe\nAcademic careers have become very competitive these days\, and the career decisions you make as a Ph.D. student or postdoc may greatly influence your chances of success later on. Choosing well your first postdoc is particularly important\, as you must ensure that you will be developing your skills while starting to make a name for yourself. When you should you start looking for a postdoc? What aspects should you consider? Where is the best place for you? In this session we will explore how to plan ahead and secure a successful postdoc\, and how to prepare for the next steps on the career ladder. \n  \nAfter obtaining an engineering diploma in biotechnology from her native France\, Elisabeth went to the United Kingdom to pursue her Ph.D. in immunology at the University of Bristol. Finding her calling in science journalism\, she went on to obtain a postgraduate diploma in journalism studies from Cardiff University\, with a bursary from the Association of British Science Writers. Since 2002\, Elisabeth has been working for Science Careers\, the online jobs and career guidance magazine of the journal Science – first in Cambridge as U.K. Editor and\, starting in 2004\, in Barcelona as Contributing Editor for Europe. Elisabeth has extensive experience covering a broad range of topics relevant to young scientists\, going from job and funding opportunities in academia to alternative careers and work-life balance. Elisabeth also regularly contributes Spanish and French news stories for Science and its policy blog Science Insider. URL:https://ibecbarcelona.eu/event/phd-discussions-complementary-skills-session-elisabeth-pain-science-careers/ CATEGORIES:PhD Discussions Complementary Skills Session END:VEVENT END:VCALENDAR