BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Institute for Bioengineering of Catalonia - ECPv6.15.20//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-WR-CALNAME:Institute for Bioengineering of Catalonia X-ORIGINAL-URL:https://ibecbarcelona.eu X-WR-CALDESC:Events for Institute for Bioengineering of Catalonia REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:Europe/Madrid BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20140330T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20141026T010000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20150329T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20151025T010000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:20160327T010000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:20161030T010000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150320T100000 DTEND;TZID=Europe/Madrid:20150320T110000 DTSTAMP:20260427T022413 CREATED:20150119T103657Z LAST-MODIFIED:20150119T103657Z UID:95834-1426845600-1426849200@ibecbarcelona.eu SUMMARY:IBEC Seminar: Romain Quidant DESCRIPTION:Biomedical applications of nanoplasmonics\n \nRomain Quidant\, ICREA professor at Institut de Ciències Fotòniques (ICFO)\nGold nanostructures\, supporting localized surface plasmon resonances\, can be designed to act upon illumination as efficient point-like sources of either light or heat\, opening plenty of new science and applications in biology and medicine. In this talk we discuss how both their optical and photothermal properties can be exploited to develop alternative\, minimally invasive strategies for the detection and therapy of cancer. \nThe first part of this presentation focuses on the use of the intense and confined optical fields bound to gold nanostructures for biosensing and optical trapping. In the frame of sensing\, we show that gold nanostructures lithographically prepared on glass can be engineered as compact and highly sensitive sensors to detect low concentrations of cancer markers in serum. As for optical trapping\, we demonstrate that plasmonic fields enable creating on-a-chip nano-optical tweezers able to trap a large number of micro- and nano- specimens with a single laser beam of low laser intensity. \nIn the second part we talk about the use of gold nanoparticles as remotely controlled point-like sources of heat for photothermal cancer therapy. We first discuss\, both theoretically and experimentally\, the physics of heat generation at the nanoscale along with the effect of the particle shape and the illumination. We then present the use of conjugated gold nanoparticles for specific cancer cell hyperthermia. URL:https://ibecbarcelona.eu/event/ibec-seminar-romain-quidant-2/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150227T120000 DTEND;TZID=Europe/Madrid:20150227T130000 DTSTAMP:20260427T022413 CREATED:20150216T094336Z LAST-MODIFIED:20150224T111247Z UID:13751-1425038400-1425042000@ibecbarcelona.eu SUMMARY:IBEC Seminar: Gilles Subra DESCRIPTION:Hybrid inorganic–biorganic peptide materials and polymers: a bottom-up approach\n \nGilles Subra\, Institut des Biomolécules Max Mousseron (IBBMM)\, Montpellier\nThe preparation of hybrid materials containing peptides relies most of the time on physical entrapment of the bioorganic moiety or on a ‘post-grafting’ procedure. In the later case\, introduction of the peptide requires surface modification and ligation chemistry performed after the synthesis of the material. In contrast\, we designed a new family of bioorganic-inorganic hybrid materials relying on the synthesis of hybrid peptide-trialkoxsilyl building blocks that can be engaged directly in a sol gel process requiring no extra reagents. \nThis bottom-up approach permits the introduction of any type of peptide in the material\, providing different functionalities\, structural features\, biological and physicochemical properties. The hybrid peptide block can be either grafted or introduced by direct synthesis. Several applications will be presented including the synthesis of silica multifunctional nanoparticles for imaging\, peptide-catalytic mesopous materials\, anti fouling glass surfaces and hydrogels. At last\, the self-assembling properties of the peptide unit can be exploited to yield a range of bio-inspired nanostructured materials. \nIn an effort to develop polymerization systems suitable for peptide sequences\, we also describe a new class of silicone-peptides biopolymers. We used well defined chlorosilyl hybrid peptides as mononeric units\, synthesized in solution or on dedicated solid support to yield linear or comb-like peptide polymers. URL:https://ibecbarcelona.eu/event/ibec-seminar-gilles-subra/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150227T120000 DTEND;TZID=Europe/Madrid:20150227T130000 DTSTAMP:20260427T022413 CREATED:20150216T094336Z LAST-MODIFIED:20150216T094336Z UID:95838-1425038400-1425042000@ibecbarcelona.eu SUMMARY:IBEC Seminar: Gilles Subra DESCRIPTION:Hybrid inorganic–biorganic peptide materials and polymers: a bottom-up approach\n \nGilles Subra\, Institut des Biomolécules Max Mousseron (IBBMM)\, Montpellier\nThe preparation of hybrid materials containing peptides relies most of the time on physical entrapment of the bioorganic moiety or on a ‘post-grafting’ procedure. In the later case\, introduction of the peptide requires surface modification and ligation chemistry performed after the synthesis of the material. In contrast\, we designed a new family of bioorganic-inorganic hybrid materials relying on the synthesis of hybrid peptide-trialkoxsilyl building blocks that can be engaged directly in a sol gel process requiring no extra reagents. \nThis bottom-up approach permits the introduction of any type of peptide in the material\, providing different functionalities\, structural features\, biological and physicochemical properties. The hybrid peptide block can be either grafted or introduced by direct synthesis. Several applications will be presented including the synthesis of silica multifunctional nanoparticles for imaging\, peptide-catalytic mesopous materials\, anti fouling glass surfaces and hydrogels. At last\, the self-assembling properties of the peptide unit can be exploited to yield a range of bio-inspired nanostructured materials. \nIn an effort to develop polymerization systems suitable for peptide sequences\, we also describe a new class of silicone-peptides biopolymers. We used well defined chlorosilyl hybrid peptides as mononeric units\, synthesized in solution or on dedicated solid support to yield linear or comb-like peptide polymers. URL:https://ibecbarcelona.eu/event/ibec-seminar-gilles-subra-2/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150227T100000 DTEND;TZID=Europe/Madrid:20150227T110000 DTSTAMP:20260427T022413 CREATED:20150119T112620Z LAST-MODIFIED:20150218T142126Z UID:11716-1425031200-1425034800@ibecbarcelona.eu SUMMARY:PhD Discussion Sessions: Silvia Pittolo and Noelia Campillo DESCRIPTION:Alloswitch: an allosteric modulator for the control of a G protein-coupled receptor with light\nSilvia Pittolo\, Nanoprobes and nanoswitches group\nControlling drug activity with light offers the possibility of enhancing pharmacological selectivity with spatial and temporal regulation\, thus enabling highly localized therapeutic effects and precise dosing patterns. We have developed and characterized what is to our knowledge the first photoswitchable allosteric modulator of a G protein–coupled receptor. Alloswitch-1 is selective for the metabotropic glutamate receptor mGlu5 and enables the optical control of endogenous mGlu5 receptors. \n  \nEffect of cyclic hypoxia mimicking obstructive sleep apnea on the expression of hypoxia-inducible factor\nNoelia Campillo\, Cellular and respiratory biomechanics group\nIntermittent hypoxia (IH)\, the process whereby tissues are recurrently subjected to episodes of low oxygen tension\, is commonly associated with several pathological conditions\, such as obstructive sleep apnea (OSA) or cancer. Increasing evidence suggests that the cyclic frequency of IH is directly related to the emergence of OSA-associated morbidities. Although HIF-1 has been identified as the critical factor regulating cell responses to hypoxia\, the molecular mechanisms supporting the pathological effects of IH remain poorly understood. This is partly due to the lack of experimental systems to study the in vitro consequences of IH patterns realistically mimicking OSA. Here we present a simple polydimethylsiloxane (PDMS) chip aimed to apply high-frequency IH patterns and cyclic stretch simulating OSA at the cell level. The device was used to study the effect of different IH frequencies on HIF-1 expression. URL:https://ibecbarcelona.eu/event/phd-discussion-sessions-silvia-pittolo-and-noelia-campillo/ CATEGORIES:PhD Discussions Session END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150227T100000 DTEND;TZID=Europe/Madrid:20150227T110000 DTSTAMP:20260427T022413 CREATED:20150119T112620Z LAST-MODIFIED:20150119T112620Z UID:95835-1425031200-1425034800@ibecbarcelona.eu SUMMARY:PhD Discussion Sessions: Silvia Pittolo and Noelia Campillo DESCRIPTION:Alloswitch: an allosteric modulator for the control of a G protein-coupled receptor with light\nSilvia Pittolo\, Nanoprobes and nanoswitches group\nControlling drug activity with light offers the possibility of enhancing pharmacological selectivity with spatial and temporal regulation\, thus enabling highly localized therapeutic effects and precise dosing patterns. We have developed and characterized what is to our knowledge the first photoswitchable allosteric modulator of a G protein–coupled receptor. Alloswitch-1 is selective for the metabotropic glutamate receptor mGlu5 and enables the optical control of endogenous mGlu5 receptors. \n  \nEffect of cyclic hypoxia mimicking obstructive sleep apnea on the expression of hypoxia-inducible factor\nNoelia Campillo\, Cellular and respiratory biomechanics group\nIntermittent hypoxia (IH)\, the process whereby tissues are recurrently subjected to episodes of low oxygen tension\, is commonly associated with several pathological conditions\, such as obstructive sleep apnea (OSA) or cancer. Increasing evidence suggests that the cyclic frequency of IH is directly related to the emergence of OSA-associated morbidities. Although HIF-1 has been identified as the critical factor regulating cell responses to hypoxia\, the molecular mechanisms supporting the pathological effects of IH remain poorly understood. This is partly due to the lack of experimental systems to study the in vitro consequences of IH patterns realistically mimicking OSA. Here we present a simple polydimethylsiloxane (PDMS) chip aimed to apply high-frequency IH patterns and cyclic stretch simulating OSA at the cell level. The device was used to study the effect of different IH frequencies on HIF-1 expression. URL:https://ibecbarcelona.eu/event/phd-discussion-sessions-silvia-pittolo-and-noelia-campillo-2/ CATEGORIES:PhD Discussions Session END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150213T100000 DTEND;TZID=Europe/Madrid:20150213T110000 DTSTAMP:20260427T022413 CREATED:20141211T155529Z LAST-MODIFIED:20150114T110203Z UID:9306-1423821600-1423825200@ibecbarcelona.eu SUMMARY:IBEC Seminar: Pia Cosma DESCRIPTION:Studying Wnt signaling activity in cell reprogramming and tissue regeneration\n \nPia Cosma\, Center for Genomic Regulation (CRG) / ICREA \nIn our group\, we are investigating the mechanisms controlling the reprogramming of somatic cells\, and our final goal is to determine if this reprogramming contributes to tissue regeneration in higher vertebrates. \nDifferentiation from zygotes has been considered as a unidirectional route in all cells of the body. Recently\, however\, it has become clear that the reverse path is also possible: the reprogramming of somatic nuclei\, i.e. the de-differentiation of somatic cells into pluripotent stem-like cells. To date\, reprogramming has been induced in vitro by transferring somatic nuclei into enucleated oocytes\, by fusing embryonic stem cells (ESCs) with somatic cells\, and by transferring specific factors into different types of somatic cell. \nWhether reprogramming can occur in vivo in higher vertebrates and what the molecular mechanisms and genes driving reprogramming are remain to be defined. We have recently shown that activation of the Wnt/β-catenin signalling pathway enhances reprogramming of somatic cells after their fusion with ESCs. Remarkably\, the activation of this signalling pathway also controls regeneration in response to damage in lower and higher vertebrates; furthermore\, cell fusion is one possible mechanism of regeneration in vertebrates. Our main goal is to determine whether in mice activation of Wnt/β-catenin signalling controls tissue regeneration by enhancing cell-fusion-mediated reprogramming. URL:https://ibecbarcelona.eu/event/ibec-seminar-pia-cosma/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150213T100000 DTEND;TZID=Europe/Madrid:20150213T110000 DTSTAMP:20260427T022413 CREATED:20141211T155529Z LAST-MODIFIED:20141211T155529Z UID:95817-1423821600-1423825200@ibecbarcelona.eu SUMMARY:IBEC Seminar: Pia Cosma DESCRIPTION:Studying Wnt signaling activity in cell reprogramming and tissue regeneration\n \nPia Cosma\, Center for Genomic Regulation (CRG) / ICREA \nIn our group\, we are investigating the mechanisms controlling the reprogramming of somatic cells\, and our final goal is to determine if this reprogramming contributes to tissue regeneration in higher vertebrates. \nDifferentiation from zygotes has been considered as a unidirectional route in all cells of the body. Recently\, however\, it has become clear that the reverse path is also possible: the reprogramming of somatic nuclei\, i.e. the de-differentiation of somatic cells into pluripotent stem-like cells. To date\, reprogramming has been induced in vitro by transferring somatic nuclei into enucleated oocytes\, by fusing embryonic stem cells (ESCs) with somatic cells\, and by transferring specific factors into different types of somatic cell. \nWhether reprogramming can occur in vivo in higher vertebrates and what the molecular mechanisms and genes driving reprogramming are remain to be defined. We have recently shown that activation of the Wnt/β-catenin signalling pathway enhances reprogramming of somatic cells after their fusion with ESCs. Remarkably\, the activation of this signalling pathway also controls regeneration in response to damage in lower and higher vertebrates; furthermore\, cell fusion is one possible mechanism of regeneration in vertebrates. Our main goal is to determine whether in mice activation of Wnt/β-catenin signalling controls tissue regeneration by enhancing cell-fusion-mediated reprogramming. URL:https://ibecbarcelona.eu/event/ibec-seminar-pia-cosma-2/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150212T000000 DTEND;TZID=Europe/Madrid:20150212T130000 DTSTAMP:20260427T022413 CREATED:20150206T085944Z LAST-MODIFIED:20150206T085944Z UID:12342-1423699200-1423746000@ibecbarcelona.eu SUMMARY:IBEC Seminar: Daniel Oliver DESCRIPTION:Crowdfunding for scientific and health projects\n \nDaniel Oliver\, Asociación Española de Crowdfunding\nMr. Oliver\, president of Spain CrowdFund\, will share his expertise fundraising for spinoff biotech companies. He will unveil the tricks that lead Iproteos to its success financing more than 100k€ through crowdfunding. Finally\, he will present Capital Cell as the first co-investment platform specialized in scientific and health projects. URL:https://ibecbarcelona.eu/event/ibec-seminar-daniel-oliver/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150212T000000 DTEND;TZID=Europe/Madrid:20150212T130000 DTSTAMP:20260427T022413 CREATED:20150206T085944Z LAST-MODIFIED:20150206T085944Z UID:95837-1423699200-1423746000@ibecbarcelona.eu SUMMARY:IBEC Seminar: Daniel Oliver DESCRIPTION:Crowdfunding for scientific and health projects\n \nDaniel Oliver\, Asociación Española de Crowdfunding\nMr. Oliver\, president of Spain CrowdFund\, will share his expertise fundraising for spinoff biotech companies. He will unveil the tricks that lead Iproteos to its success financing more than 100k€ through crowdfunding. Finally\, he will present Capital Cell as the first co-investment platform specialized in scientific and health projects. URL:https://ibecbarcelona.eu/event/ibec-seminar-daniel-oliver-2/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150203T100000 DTEND;TZID=Europe/Madrid:20150203T110000 DTSTAMP:20260427T022413 CREATED:20150119T102254Z LAST-MODIFIED:20150119T102254Z UID:95821-1422957600-1422961200@ibecbarcelona.eu SUMMARY:IBEC Seminar: Ralph G. Andrzejak DESCRIPTION:Application of nonlinear signal analysis to electroencephalographic recordings from epilepsy patients\n \nTenure Associate Professor · Department of Information and Communication Technologies · Universitat Pompeu Fabra\nNonlinear time series analysis allows characterizing dynamical systems in which nonlinearity gives rise to a complex\, seemingly irregular temporal evolution. Importantly\, these nonlinear techniques can extract information from real-world experimental signals that cannot be resolved by classical linear techniques\, such as spectral analysis. Nonlinear time series analysis can\, for example\, help to discriminate nonlinear deterministic and linear stochastic dynamics or to characterize directional interactions between dynamics. In application to signals measured from the brain\, this analysis can contribute to the understanding of brain functions and dysfunctions. It can thereby advance cognitive neuroscience and neurology. \nIn this seminar\, I will at first illustrate some fundamental concepts of nonlinear time series analysis. Subsequently\, we will review some basic facts about the disease epilepsy\, epilepsy surgery and intracranial electroencephalographic recordings (EEG) from epilepsy patients. I will then show an application of nonlinear time series analysis to EEG recordings from the seizure-free interval of epilepsy patients undergoing pre-surgical diagnostics. Results of this application allowed us to localize the seizure generating brain area without the necessity of observing actual seizure activity – a finding of clear clinical relevance. URL:https://ibecbarcelona.eu/event/ibec-seminar-danny-van-noort-2/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150203T100000 DTEND;TZID=Europe/Madrid:20150203T110000 DTSTAMP:20260427T022413 CREATED:20150119T102254Z LAST-MODIFIED:20150128T103719Z UID:11712-1422957600-1422961200@ibecbarcelona.eu SUMMARY:IBEC Seminar: Ralph G. Andrzejak DESCRIPTION:Application of nonlinear signal analysis to electroencephalographic recordings from epilepsy patients\n \nTenure Associate Professor · Department of Information and Communication Technologies · Universitat Pompeu Fabra\nNonlinear time series analysis allows characterizing dynamical systems in which nonlinearity gives rise to a complex\, seemingly irregular temporal evolution. Importantly\, these nonlinear techniques can extract information from real-world experimental signals that cannot be resolved by classical linear techniques\, such as spectral analysis. Nonlinear time series analysis can\, for example\, help to discriminate nonlinear deterministic and linear stochastic dynamics or to characterize directional interactions between dynamics. In application to signals measured from the brain\, this analysis can contribute to the understanding of brain functions and dysfunctions. It can thereby advance cognitive neuroscience and neurology. \nIn this seminar\, I will at first illustrate some fundamental concepts of nonlinear time series analysis. Subsequently\, we will review some basic facts about the disease epilepsy\, epilepsy surgery and intracranial electroencephalographic recordings (EEG) from epilepsy patients. I will then show an application of nonlinear time series analysis to EEG recordings from the seizure-free interval of epilepsy patients undergoing pre-surgical diagnostics. Results of this application allowed us to localize the seizure generating brain area without the necessity of observing actual seizure activity – a finding of clear clinical relevance. URL:https://ibecbarcelona.eu/event/ibec-seminar-danny-van-noort/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150130T100000 DTEND;TZID=Europe/Madrid:20150130T110000 DTSTAMP:20260427T022413 CREATED:20150112T161709Z LAST-MODIFIED:20150123T110636Z UID:11431-1422612000-1422615600@ibecbarcelona.eu SUMMARY:PhD Discussions Complementary Skills Session: Intellectual and industrial property DESCRIPTION:“Turning science into business”\n \nErnest Mendoza\, Universitat Politècnica de Catalunya / Goldemar Solutions \n\n(with an introduction by Dr. Arantxa Sanz\, IBEC) \nDr Ernest Mendoza\, leader of the Applied Nanomaterials research group at the Universitat Politècnica of Catalunya and General Manager and Founder of Goldemar Solution\, a spin-off of the same university\, will talk about his experience as an entrepreneur and how he succeeded in setting up a new company based on the results of his research. \nThe session will be introduced by Arantxa Sanz\, Head of the Knowledge Exchange Unit at IBEC\, who will give a short review of Intellectual Property and Tech Transfer issues at the institute. URL:https://ibecbarcelona.eu/event/phd-discussions-complementary-skills-session-intellectual-and-industrial-property/ CATEGORIES:PhD Discussions Complementary Skills Session END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150130T100000 DTEND;TZID=Europe/Madrid:20150130T110000 DTSTAMP:20260427T022413 CREATED:20150112T161709Z LAST-MODIFIED:20150112T161709Z UID:95820-1422612000-1422615600@ibecbarcelona.eu SUMMARY:PhD Discussions Complementary Skills Session: Intellectual and industrial property DESCRIPTION:“Turning science into business”\n \nErnest Mendoza\, Universitat Politècnica de Catalunya / Goldemar Solutions \n\n(with an introduction by Dr. Arantxa Sanz\, IBEC) \nDr Ernest Mendoza\, leader of the Applied Nanomaterials research group at the Universitat Politècnica of Catalunya and General Manager and Founder of Goldemar Solution\, a spin-off of the same university\, will talk about his experience as an entrepreneur and how he succeeded in setting up a new company based on the results of his research. \nThe session will be introduced by Arantxa Sanz\, Head of the Knowledge Exchange Unit at IBEC\, who will give a short review of Intellectual Property and Tech Transfer issues at the institute. URL:https://ibecbarcelona.eu/event/phd-discussions-complementary-skills-session-intellectual-and-industrial-property-2/ CATEGORIES:PhD Discussions Complementary Skills Session END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150116T100000 DTEND;TZID=Europe/Madrid:20150116T110000 DTSTAMP:20260427T022413 CREATED:20141113T150633Z LAST-MODIFIED:20150112T161125Z UID:2488-1421402400-1421406000@ibecbarcelona.eu SUMMARY:IBEC Seminar: David Caballero DESCRIPTION:The cell ratchet: interplay between protrusion activity and adhesion determines cell motion\n \nDavid Caballero\, Nanobioengineering group\, IBEC\nMany physiological and pathological processes involve directed cell motion\, either collective or as single cells. Typically\, migrating cells are characterized by a polarized morphology with extending and retracting protrusions at the leading edge. However\, cell motion is a much more complex phenomenon. Cells show heterogeneous morphologies and high protrusive dynamics. This prevents the quantitative prediction of cell motion and the identification of the cellular mechanism responsible of directionality. In this seminar\, I discuss about the importance of protrusion fluctuations in the physicochemical mechanism of directed cell motion. I show how their spatiotemporal distribution and dynamics determines univocally the direction of cell motion on NIH3T3 fibroblasts deposited on micropatterned adhesive ratchets. Novel physical concepts describing short-term cell motility are introduced which allows the prediction of parameters characteristic of long-term motion of cells. The obtained results may have important implications for the study of biological phenomena where directed cell migration is involved\, such as morphogenesis or cancer. URL:https://ibecbarcelona.eu/event/ibec-seminar-david-caballero-ibec/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150116T100000 DTEND;TZID=Europe/Madrid:20150116T110000 DTSTAMP:20260427T022413 CREATED:20141113T150633Z LAST-MODIFIED:20141113T150633Z UID:95816-1421402400-1421406000@ibecbarcelona.eu SUMMARY:IBEC Seminar: David Caballero DESCRIPTION:The cell ratchet: interplay between protrusion activity and adhesion determines cell motion\n \nDavid Caballero\, Nanobioengineering group\, IBEC\nMany physiological and pathological processes involve directed cell motion\, either collective or as single cells. Typically\, migrating cells are characterized by a polarized morphology with extending and retracting protrusions at the leading edge. However\, cell motion is a much more complex phenomenon. Cells show heterogeneous morphologies and high protrusive dynamics. This prevents the quantitative prediction of cell motion and the identification of the cellular mechanism responsible of directionality. In this seminar\, I discuss about the importance of protrusion fluctuations in the physicochemical mechanism of directed cell motion. I show how their spatiotemporal distribution and dynamics determines univocally the direction of cell motion on NIH3T3 fibroblasts deposited on micropatterned adhesive ratchets. Novel physical concepts describing short-term cell motility are introduced which allows the prediction of parameters characteristic of long-term motion of cells. The obtained results may have important implications for the study of biological phenomena where directed cell migration is involved\, such as morphogenesis or cancer. URL:https://ibecbarcelona.eu/event/ibec-seminar-david-caballero-ibec-2/ CATEGORIES:IBEC Seminar END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150115T110000 DTEND;TZID=Europe/Madrid:20150115T130000 DTSTAMP:20260427T022413 CREATED:20150112T160445Z LAST-MODIFIED:20150112T161247Z UID:11429-1421319600-1421326800@ibecbarcelona.eu SUMMARY:PhD Thesis defence: Marta Sanmartí DESCRIPTION:“Study of natural nanovesicles carrying olfactory receptors for the development of biosensing platforms”\n \nMarta Sanmartí-Espinal\, Nanobioengineering group\, IBEC\nMarta will be defending her PhD thesis on Thursday 15th January at 11:00 in the Aula Magna Enric Casassas\, Facultat de Química\, UB. \nEverybody is welcome to attend. \n—\nIf you’re an IBEC PhD student and would like to advertise your PhD defense on the IBEC calendar\, please contact vleigh@ibecbarcelona.eu URL:https://ibecbarcelona.eu/event/phd-thesis-defence-marta-sanmarti/ LOCATION:Aula Magna Enric Casassas\, Facultat de Química\, UB\, Carrer Martí i Franquès\, 1\, 08028 Barcelona\, Spain CATEGORIES:PhD Thesis Defence END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150115T110000 DTEND;TZID=Europe/Madrid:20150115T130000 DTSTAMP:20260427T022413 CREATED:20150112T160445Z LAST-MODIFIED:20150112T160445Z UID:95819-1421319600-1421326800@ibecbarcelona.eu SUMMARY:PhD Thesis defence: Marta Sanmartí DESCRIPTION:“Study of natural nanovesicles carrying olfactory receptors for the development of biosensing platforms”\n \nMarta Sanmartí-Espinal\, Nanobioengineering group\, IBEC\nMarta will be defending her PhD thesis on Thursday 15th January at 11:00 in the Aula Magna Enric Casassas\, Facultat de Química\, UB. \nEverybody is welcome to attend. \n—\nIf you’re an IBEC PhD student and would like to advertise your PhD defense on the IBEC calendar\, please contact vleigh@ibecbarcelona.eu URL:https://ibecbarcelona.eu/event/phd-thesis-defence-marta-sanmarti-2/ LOCATION:Aula Magna Enric Casassas\, Facultat de Química\, UB\, Carrer Martí i Franquès\, 1\, 08028 Barcelona\, Spain CATEGORIES:PhD Thesis Defence END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150109T110000 DTEND;TZID=Europe/Madrid:20150109T130000 DTSTAMP:20260427T022413 CREATED:20150112T155824Z LAST-MODIFIED:20150112T161326Z UID:11427-1420801200-1420808400@ibecbarcelona.eu SUMMARY:PhD Thesis defence: Riccardo Levato DESCRIPTION:“Injectable biodegradable carriers for the delivery of therapeutic agents and tissue engineering”\n \nRiccardo Levato\, Biomaterials for regenerative therapies group\, IBEC\nRiccardo will be defending his PhD thesis on Friday 9th January at 11:00 in the Sala d’Actes de la Facultat de Matemàtiques i Estadística\, c. Pau Gargallo 5\, 08028 Barcelona. \nEverybody is welcome to attend. \n—\nIf you’re an IBEC PhD student and would like to advertise your PhD defense on the IBEC calendar\, please contact vleigh@ibecbarcelona.eu URL:https://ibecbarcelona.eu/event/phd-thesis-defence-riccardo-levato/ LOCATION:Sala d’Actes de la Facultat de Matemàtiques i Estadística\, c. Pau Gargallo 5\, 08028 Barcelona\, Spain CATEGORIES:PhD Thesis Defence END:VEVENT BEGIN:VEVENT DTSTART;TZID=Europe/Madrid:20150109T110000 DTEND;TZID=Europe/Madrid:20150109T130000 DTSTAMP:20260427T022413 CREATED:20150112T155824Z LAST-MODIFIED:20150112T155824Z UID:95818-1420801200-1420808400@ibecbarcelona.eu SUMMARY:PhD Thesis defence: Riccardo Levato DESCRIPTION:“Injectable biodegradable carriers for the delivery of therapeutic agents and tissue engineering”\n \nRiccardo Levato\, Biomaterials for regenerative therapies group\, IBEC\nRiccardo will be defending his PhD thesis on Friday 9th January at 11:00 in the Sala d’Actes de la Facultat de Matemàtiques i Estadística\, c. Pau Gargallo 5\, 08028 Barcelona. \nEverybody is welcome to attend. \n—\nIf you’re an IBEC PhD student and would like to advertise your PhD defense on the IBEC calendar\, please contact vleigh@ibecbarcelona.eu URL:https://ibecbarcelona.eu/event/phd-thesis-defence-riccardo-levato-2/ LOCATION:Sala d’Actes de la Facultat de Matemàtiques i Estadística\, c. Pau Gargallo 5\, 08028 Barcelona\, Spain CATEGORIES:PhD Thesis Defence END:VEVENT END:VCALENDAR