Institute for Bioengineering of Catalonia

reSearch4Talent 2017
2017-05-12 11:00 - 14:00 (Europe/Madrid) | Sala Dolors Aleu, Cluster II, Parc Científic de Barcelona, Barcelona, Spain
reSearch4Talent 2017
On Friday 12th May 2017 we’ll open our doors again to undergraduate and masters students interested in a research career.
This will be the third edition of reSearch4Talent.

PROGRAMME:
11:00 Welcome
11:15 Director’s talk, “What is IBEC?” and overview of research groups
11:50 HR Speech
12:00 Careers Fair: a chance for participants to mingle and chat with our researchers
13:00 – 14:00 Lab visits

VENUE:
Institute for Bioengineering of Catalonia (IBEC)
Dolors Aleu Room
Parc Científic de Barcelona (PCB)
C. Baldiri Reixac, 4-8, Barcelona
More details here.

Mentoring skills for Senior Scientists
2017-05-18 08:00 - 17:00
Training activity in Leadership&management skills.
The aim of the two workshops is to prepare Senior Scientists for their roles of Mentor in the IBEC mentoring programme. They will learn key skills to encourage and support the learning of their mentees and consider how to manage the different stages in the process. They will also identify what their personal developmental objectives are in their own career paths.
Dates:
18th and 24th May, from 9.30 -1:30pm
In person class sessions = 8 hours in two half days + Pre-reading material
Target group:
Group Leaders participating in the IBEC’s Mentoring Programme.
Provider: Louise Schubert.

PhD Committee: Laser Tag
2017-05-18 19:00 - 23:30 | Play-Point, Comte Borrell 88, Barcelona, Spain
Change your labcoat for a laser gun and fight with your team for victory!
Play-Point (Comte Borrell 88)
The meeting time will be 7.00pm. It’s only 2€ for IBEC members and 10€ for non-IBEC (give the money to PhD committee before May 15th).
Afterwards, around 9pm, we will go for some tapas and drinks (place to be decided by the winning team).
To register please fill the Doodle. Write your email with the number of people you will come (e.g. David + 1, ddd@ibecbarcelona.eu).

IBEC Seminar: Verena Ruprecht
2017-05-19 10:00 - 11:00
Tuning cell and tissue dynamics by the biomechanical microenvironment
Dr. Verena Ruprecht, Cell & Developmental Biology program, CRG, Barcelona (Spain)
Research in our lab is focused on the control of cell and tissue dynamics in 3D environments. We study how single cells process multifactorial mechanochemical information from their surrounding and generate adaptive output dynamics such as shape change, cell polarization and migration that collectively impact on tissue development and morphogenesis. We use Zebrafish embryos and primary embryonic progenitor stem cells as a model system to study molecular and cellular mechanisms driving complex three-dimensional tissue rearrangements and patterning in the embryo. Our lab follows a highly interdisciplinary approach combining molecular and cell biological tools with quantitative imaging approaches and advanced fluorescence microscopy. We implement a dual experiment strategy of in vivo experiments and minimalistic in vitro culture assays that allow for reconstituting the complexity of tissue morphogenesis in simplified environments.
In this talk I will specifically focus on how the 3D cellular microenvironment modulates cytoskeletal dynamics and motile cell behaviour and how a combination of physics and biology can help to elucidate generic patterns in cell motility.

Technology Transfer
2017-05-23 11:00 - 13:00
Training activity in Innovation skills.
The objective of the session will be to understand what the effective technology transfer is, and what opportunities and constrains brings to a researcher.
Dates:
23rd May 2017, from 11 to 13H. In person class sessions: 2 hours
Target group:
All IBEC members

Good practices in a multidisciplinary lab
2017-05-24 10:00 - 13:00
Training activity in Scientific tools & techniques.
The objective of this workshop is to acquire the good practices necessary in a multidisciplinary laboratory to ensure the highest quality of the results.
Dates:
The workshop will be offered twice a year.

24th May, from 10 to 13pm
October

Target group:
Vocational training Students, Undergraduate students, Master students and PhDs in their first year.
Provider: Internal Trainer, IBEC Risk PRevention representatives.

PhD Discussions Session: Carlos Pérez and Víctor González
2017-05-26 10:00 - 11:00
Active wetting of epithelial tissues
Carlos Pérez, Integrative cell and tissue dynamics group
Key biological processes such as cancer and development are characterized by drastic transitions in tissue morphology. These rearrangements have been classically studied as a wetting problem. According to this theory, wettability of a substrate by an epithelium is determined by the competition between cell-cell and cell-substrate adhesion energies. In contrast, we found that, far from a passive process, tissue dewetting is an active process driven by tissue internal forces. Experimentally, we reproduced epithelial dewetting by promoting a progressive formation of intercellular junctions in a monolayer of epithelial cells. Interestingly, the formation of intercellular junctions produces an increase in cell contractility, with the subsequent increase in traction and intercellular stress. At a certain time, tissue tension overcomes cell-substrate maximum adhesion and the monolayer spontaneously dewets the substrate. We developed an active polar fluid model, finding both theoretically and experimentally that critical contractility to promote wetting-dewetting transition depends on cell-substrate adhesion and, unexpectedly, on tissue size. As a whole, this work generalizes wetting theory to living tissues, unveiling unprecedented properties due to their unique active nature.

Binding of ZO-1 to α5β1 integrins regulates the mechanical properties of α5β1-fibronectin links
Víctor González, Cellular and molecular mechanobiology group
Fundamental processes in cell adhesion, motility, and rigidity adaptation are regulated by integrin-mediated adhesion to the extracellular matrix (ECM). The link between the ECM component fibronectin (fn) and integrin α5β1 forms a complex with ZO-1 in cells at the edge of migrating monolayers, regulating cell migration. However, how this complex affects the α5β1-fn link is unknown. Here we show that the α5β1/ZO-1 complex decreases the resistance to force of α5β1–fn adhesions located at the edge of migrating cell monolayers while also increasing α5β1 recruitment. Consistently with a molecular clutch model of adhesion, this effect of ZO-1 leads to a decrease in the density and intensity of adhesions in cells at the edge of migrating monolayers. Taken together, our results unveil a new mode of integrin regulation through modification of the mechanical properties of integrin–ECM links, which may be harnessed by cells to control adhesion and migration.

11a FESTA DE LA CIÈNCIA
2017-05-27 00:00 - 2017-05-28 23:59, 2017-05-27 - 2017-05-28 | Parc de la Ciutadella
Part of the Festival Barcelona Ciència
Saturday 27th-Sunday 28th May, Parc de la Ciutadella
27/05 – 17:20h
BIOROBOTS HÍBRIDS: LA FUSIÓ DE TECNOLOGIA I LA VIDA
Microxerrada, a partir de 16 anys
A càrrec de Rafael Mestre, Institut de Bioenginyeria de Catalunya (IBEC)
28/05 – 12:40h
CREANT NANOPARTÍCULES PER A LA REGENERACIÓ DE TEIXITS
Microxerrada, a partir de 16 anys
A càrrec d’Andrea Martín, Institut de Bioenginyeria de Catalunya (IBEC)
28/05 – 13:10h
COM ES CREEN LES XARXES DE VASOS SANGUINIS I CAPIL·LARS?
Microxerrada, a partir de 16 anys
A càrrec d’Andrea Malandrino, Institut de Bioenginyeria de Catalunya (IBEC)
28/05 – 14:40h
BIOSENSORS PORTÀTILS A LA CARTA
Microxerrada, a partir de 16 anys
A càrrec d’Agostino Romero, Institut de Bioenginyeria de Catalunya (IBEC)
http://lameva.barcelona.cat/barcelonaciencia/en/

IBEC Seminar: Esteve Trias & Oscar Fariñas, BTB
2017-06-02 10:00 - 11:00 | IBEC, floor 11, Tower I, Baldiri Reixac 4-8, 08028 Barcelona, Spain
Research challenges of the Barcelona Tissue Bank
Esteve Trias, Oscar Fariñas – Barcelona Tissue Bank (Banc de Sang I Teixits)
The Barcelona Tissue Bank (BTB) is a multi-tissue bank which belongs to the Banc de Sang i Teixits (BST), a public company of the Department of Health of the Generalitat de Catalunya, whose mission is to ensure the supply and proper use of blood and Tissue in Catalonia.
The BTB controls the entire process of donation and transplantation globally, from the process of detection and evaluation of the potential donor, obtention or extraction, processing of the different tissues, storage and distribution until transplantation.
In the BTB we can distinguish five major banks: ocular, cardiovascular, skin, musculoskeletal and reproductive.
Musculoskeletal tissue bank represents 50% of the activity of BTB, covering approximately 85% of transplanted tissue in the Spanish state. Different types of tissues are processed through a decontamination process to ensure maximum security. The purpose of the great variety of processed tissues is to meet the different needs of surgeons, being the most common ligament reconstruction, filling bone defects, tumour surgery and meniscal transplantation.
Research, development and innovation of new products and processes are constant priorities to provide the best solution for patients by setting up different lines of R & D in the short, medium and long term.

IBEC's 10th Anniversary Symposium
2017-06-06 15:00 - 2017-06-07 17:00 | AXA Auditorium, L'illa Diagonal, Av. Diagonal 547 , Barcelona, 08029
Bioengineering for future medicine
This year’s symposium is extra special, as it marks ten years of research results since IBEC’s inception at the end of 2006.
Throughout 2017 we’ll be celebrating our first decade of activity with various events, among them this year’s symposium on Bioengineering for Future Medicine.
The IBEC annual symposium brings together high-profile international experts for an open forum for interdisciplinary discussions and networking. The whole scientific community is invited to participate.
Researchers are welcome to present their projects in a poster format for the 10th Symposium. Some of these contributions will be selected, by the scientific committee, for an oral flash presentation.
Visit the symposium website for more details and to register.
Important deadlines:
Abstract submission Alumni: 23rd April 2017 (notification of acceptance: 28th April)
Abstract submission IBEC members: 1st May 2017 (notification of acceptance: 19th May)
Registration deadline: 24th May 2017
