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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170227T093000
DTEND;TZID=Europe/Madrid:20170302T163000
DTSTAMP:20260405T175911
CREATED:20170214T121749Z
LAST-MODIFIED:20170214T121749Z
UID:95995-1488187800-1488472200@ibecbarcelona.eu
SUMMARY:YoMo:
The Youth Mobile Festival
DESCRIPTION:IBEC at the Mobile World Congress\nIBEC will take part in the Youth Mobile Festival (YOMO) of the Mobile World Congress\, the world’s largest gathering for the mobile industry\, at the end of February with an interactive stand about bioengineering for cardiac regeneration. \nWith the aid of a 3D pen\, attendees will be able to replicate one of the techniques that are used for research in this area. The activity will reflect on the advantages and disadvantages of these types of therapies\, and visitors will also have the opportunity to examine some tissue samples made with IBEC’s 3D bioprinter using a microscope. \nYOMO\, with 1200 hours of live theatre shows\, interactive workshops\, and dozens of hands-on activities\, is expected to attract up to 20\,000 10-16 year olds from across Catalonia and Spain.
URL:https://ibecbarcelona.eu/event/yomo-the-youth-mobile-festival-2/
LOCATION:Fira de Barcelona\, Montjuïc Hall 1\, Barcelona\, Spain
CATEGORIES:Outreach / Fair / Festival
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170227T093000
DTEND;TZID=Europe/Madrid:20170302T163000
DTSTAMP:20260405T175911
CREATED:20170214T121749Z
LAST-MODIFIED:20170214T121749Z
UID:95996-1488187800-1488472200@ibecbarcelona.eu
SUMMARY:YoMo:
The Youth Mobile Festival
DESCRIPTION:IBEC at the Mobile World Congress\nIBEC will take part in the Youth Mobile Festival (YOMO) of the Mobile World Congress\, the world’s largest gathering for the mobile industry\, at the end of February with an interactive stand about bioengineering for cardiac regeneration. \nWith the aid of a 3D pen\, attendees will be able to replicate one of the techniques that are used for research in this area. The activity will reflect on the advantages and disadvantages of these types of therapies\, and visitors will also have the opportunity to examine some tissue samples made with IBEC’s 3D bioprinter using a microscope. \nYOMO\, with 1200 hours of live theatre shows\, interactive workshops\, and dozens of hands-on activities\, is expected to attract up to 20\,000 10-16 year olds from across Catalonia and Spain.
URL:https://ibecbarcelona.eu/event/yomo-the-youth-mobile-festival-3/
LOCATION:Fira de Barcelona\, Montjuïc Hall 1\, Barcelona\, Spain
CATEGORIES:Outreach / Fair / Festival
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170227T093000
DTEND;TZID=Europe/Madrid:20170302T163000
DTSTAMP:20260405T175911
CREATED:20170214T121749Z
LAST-MODIFIED:20170801T105201Z
UID:27632-1488187800-1488472200@ibecbarcelona.eu
SUMMARY:YoMo:
The Youth Mobile Festival
DESCRIPTION:IBEC at the Mobile World Congress\nIBEC will take part in the Youth Mobile Festival (YOMO) of the Mobile World Congress\, the world’s largest gathering for the mobile industry\, at the end of February with an interactive stand about bioengineering for cardiac regeneration. \nWith the aid of a 3D pen\, attendees will be able to replicate one of the techniques that are used for research in this area. The activity will reflect on the advantages and disadvantages of these types of therapies\, and visitors will also have the opportunity to examine some tissue samples made with IBEC’s 3D bioprinter using a microscope. \nYOMO\, with 1200 hours of live theatre shows\, interactive workshops\, and dozens of hands-on activities\, is expected to attract up to 20\,000 10-16 year olds from across Catalonia and Spain.
URL:https://ibecbarcelona.eu/event/yomo%e2%80%a8the-youth-mobile-festival/
LOCATION:Fira de Barcelona\, Montjuïc Hall 1\, Barcelona\, Spain
CATEGORIES:Outreach / Fair / Festival
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170224T090000
DTEND;TZID=Europe/Madrid:20170224T180000
DTSTAMP:20260405T175911
CREATED:20170214T155207Z
LAST-MODIFIED:20170214T155207Z
UID:95999-1487926800-1487959200@ibecbarcelona.eu
SUMMARY:Bioengineering Workshop - ASBTEC & IBEC
DESCRIPTION:Després de l’èxit del Workshop de Biologia Sintètica que vam organitzar des de l’ASBTEC ara fa un any\, tenim l’honor de presentar-vos un nou Workshop sobre Bioenginyeria\, organitzat conjuntament amb l’Institut de Bioenginyeria de Catalunya (IBEC). Aquest camp de les biociències s’ha posat tant de moda per la incorporació sistemàtica de noves tecnologies (especialment les d’escales microscòpiques) a la biologia clàssica per tal de tirar endavant nous projectes i possibilitats. \n\nEl dia 24 de Febrer us tenim preparat una jornada completa de presentació de la Bioenginyeria. Amb un programa completíssim i variat (ja el podeu consultar al cartell oficial)\, centrarem el Workshop en tres grans blocs: \n\nPresentació de les principals branques de la Bioenginyeria. Pentintarem\, entre d’altres\, els biomaterials\, la manipulació cel·lular\, la nanotecnologia\, així com els principals projectes catalans i europeus. Quatre investigadors pioners en els seus camps ens mostraran els grans potencials d’aquestes branques.\nIntroducció a les principals tècniques que han fet avançar la bioenginyeria: Impresora 3D\, Organ-on-a-chip i CRISPR. Descobrirem aquestes tècniques les quals tots hem sentit a parlar i seran imprescindibles en un futur ben pròxim.\nTaula rodona i discussió informal amb joves bioenginyers i bioenginyeres. Tindrem la oportunitat de sentir l’experiència i compartir un pica-pica amb diferents perfils de doctorands i doctors en bioenginyeria. Des de la microscopia o l’optogenètica\, fins la indústria mèdica\, passant per la reprogramació cel·lular.\n\nQualsevol estudiant o professional amb motivacions per la Bioenginyeria serà més que benvingut. Amb una rigurositat científica ben estricte\, aquest esdeveniment està pensat per tots els estrats de biociències (estudiants de Grau\, estudiants de Màster i professionals del sector) \nAquest Workshop serà íntegrament en anglès. \n\nLloc: Sala Dolors Aleu\, Institut de Bioenginyeria de Catalunya (IBEC)\nData: 24 de Febrer de 2017\nHorari: 09h – 18h\n\nPreu: 5€ socis d’ASBTEC o membres de l’IBEC. 20€ no socis.\n15€ inscripció + associar-se a l’ASBTEC\nRegister at http://asbtec.blogspot.com.es/
URL:https://ibecbarcelona.eu/event/bioengineering-workshop-asbtec-ibec-3/
LOCATION:Sala Dolors Aleu\, Cluster II\, Parc Científic de Barcelona\, Barcelona\, Spain
CATEGORIES:Joint seminar / workshop / symposium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170224T090000
DTEND;TZID=Europe/Madrid:20170224T180000
DTSTAMP:20260405T175911
CREATED:20170214T155207Z
LAST-MODIFIED:20170214T155207Z
UID:96000-1487926800-1487959200@ibecbarcelona.eu
SUMMARY:Bioengineering Workshop - ASBTEC & IBEC
DESCRIPTION:Després de l’èxit del Workshop de Biologia Sintètica que vam organitzar des de l’ASBTEC ara fa un any\, tenim l’honor de presentar-vos un nou Workshop sobre Bioenginyeria\, organitzat conjuntament amb l’Institut de Bioenginyeria de Catalunya (IBEC). Aquest camp de les biociències s’ha posat tant de moda per la incorporació sistemàtica de noves tecnologies (especialment les d’escales microscòpiques) a la biologia clàssica per tal de tirar endavant nous projectes i possibilitats. \n\nEl dia 24 de Febrer us tenim preparat una jornada completa de presentació de la Bioenginyeria. Amb un programa completíssim i variat (ja el podeu consultar al cartell oficial)\, centrarem el Workshop en tres grans blocs: \n\nPresentació de les principals branques de la Bioenginyeria. Pentintarem\, entre d’altres\, els biomaterials\, la manipulació cel·lular\, la nanotecnologia\, així com els principals projectes catalans i europeus. Quatre investigadors pioners en els seus camps ens mostraran els grans potencials d’aquestes branques.\nIntroducció a les principals tècniques que han fet avançar la bioenginyeria: Impresora 3D\, Organ-on-a-chip i CRISPR. Descobrirem aquestes tècniques les quals tots hem sentit a parlar i seran imprescindibles en un futur ben pròxim.\nTaula rodona i discussió informal amb joves bioenginyers i bioenginyeres. Tindrem la oportunitat de sentir l’experiència i compartir un pica-pica amb diferents perfils de doctorands i doctors en bioenginyeria. Des de la microscopia o l’optogenètica\, fins la indústria mèdica\, passant per la reprogramació cel·lular.\n\nQualsevol estudiant o professional amb motivacions per la Bioenginyeria serà més que benvingut. Amb una rigurositat científica ben estricte\, aquest esdeveniment està pensat per tots els estrats de biociències (estudiants de Grau\, estudiants de Màster i professionals del sector) \nAquest Workshop serà íntegrament en anglès. \n\nLloc: Sala Dolors Aleu\, Institut de Bioenginyeria de Catalunya (IBEC)\nData: 24 de Febrer de 2017\nHorari: 09h – 18h\n\nPreu: 5€ socis d’ASBTEC o membres de l’IBEC. 20€ no socis.\n15€ inscripció + associar-se a l’ASBTEC\nRegister at http://asbtec.blogspot.com.es/
URL:https://ibecbarcelona.eu/event/bioengineering-workshop-asbtec-ibec-4/
LOCATION:Sala Dolors Aleu\, Cluster II\, Parc Científic de Barcelona\, Barcelona\, Spain
CATEGORIES:Joint seminar / workshop / symposium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170224T090000
DTEND;TZID=Europe/Madrid:20170224T180000
DTSTAMP:20260405T175911
CREATED:20170214T155207Z
LAST-MODIFIED:20170801T110449Z
UID:27662-1487926800-1487959200@ibecbarcelona.eu
SUMMARY:Bioengineering Workshop - ASBTEC & IBEC
DESCRIPTION:Després de l’èxit del Workshop de Biologia Sintètica que vam organitzar des de l’ASBTEC ara fa un any\, tenim l’honor de presentar-vos un nou Workshop sobre Bioenginyeria\, organitzat conjuntament amb l’Institut de Bioenginyeria de Catalunya (IBEC). Aquest camp de les biociències s’ha posat tant de moda per la incorporació sistemàtica de noves tecnologies (especialment les d’escales microscòpiques) a la biologia clàssica per tal de tirar endavant nous projectes i possibilitats. \n\nEl dia 24 de Febrer us tenim preparat una jornada completa de presentació de la Bioenginyeria. Amb un programa completíssim i variat (ja el podeu consultar al cartell oficial)\, centrarem el Workshop en tres grans blocs: \n\nPresentació de les principals branques de la Bioenginyeria. Pentintarem\, entre d’altres\, els biomaterials\, la manipulació cel·lular\, la nanotecnologia\, així com els principals projectes catalans i europeus. Quatre investigadors pioners en els seus camps ens mostraran els grans potencials d’aquestes branques.\nIntroducció a les principals tècniques que han fet avançar la bioenginyeria: Impresora 3D\, Organ-on-a-chip i CRISPR. Descobrirem aquestes tècniques les quals tots hem sentit a parlar i seran imprescindibles en un futur ben pròxim.\nTaula rodona i discussió informal amb joves bioenginyers i bioenginyeres. Tindrem la oportunitat de sentir l’experiència i compartir un pica-pica amb diferents perfils de doctorands i doctors en bioenginyeria. Des de la microscopia o l’optogenètica\, fins la indústria mèdica\, passant per la reprogramació cel·lular.\n\nQualsevol estudiant o professional amb motivacions per la Bioenginyeria serà més que benvingut. Amb una rigurositat científica ben estricte\, aquest esdeveniment està pensat per tots els estrats de biociències (estudiants de Grau\, estudiants de Màster i professionals del sector) \nAquest Workshop serà íntegrament en anglès. \n\nLloc: Sala Dolors Aleu\, Institut de Bioenginyeria de Catalunya (IBEC)\nData: 24 de Febrer de 2017\nHorari: 09h – 18h\n\nPreu: 5€ socis d’ASBTEC o membres de l’IBEC. 20€ no socis.\n15€ inscripció + associar-se a l’ASBTEC\nRegister at http://asbtec.blogspot.com.es/
URL:https://ibecbarcelona.eu/event/bioengineering-workshop-asbtec-ibec/
LOCATION:Sala Dolors Aleu\, Cluster II\, Parc Científic de Barcelona\, Barcelona\, Spain
CATEGORIES:Joint seminar / workshop / symposium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170224T090000
DTEND;TZID=Europe/Madrid:20170224T180000
DTSTAMP:20260405T175911
CREATED:20170214T155207Z
LAST-MODIFIED:20170214T155207Z
UID:95998-1487926800-1487959200@ibecbarcelona.eu
SUMMARY:Bioengineering Workshop - ASBTEC & IBEC
DESCRIPTION:Després de l’èxit del Workshop de Biologia Sintètica que vam organitzar des de l’ASBTEC ara fa un any\, tenim l’honor de presentar-vos un nou Workshop sobre Bioenginyeria\, organitzat conjuntament amb l’Institut de Bioenginyeria de Catalunya (IBEC). Aquest camp de les biociències s’ha posat tant de moda per la incorporació sistemàtica de noves tecnologies (especialment les d’escales microscòpiques) a la biologia clàssica per tal de tirar endavant nous projectes i possibilitats. \n\nEl dia 24 de Febrer us tenim preparat una jornada completa de presentació de la Bioenginyeria. Amb un programa completíssim i variat (ja el podeu consultar al cartell oficial)\, centrarem el Workshop en tres grans blocs: \n\nPresentació de les principals branques de la Bioenginyeria. Pentintarem\, entre d’altres\, els biomaterials\, la manipulació cel·lular\, la nanotecnologia\, així com els principals projectes catalans i europeus. Quatre investigadors pioners en els seus camps ens mostraran els grans potencials d’aquestes branques.\nIntroducció a les principals tècniques que han fet avançar la bioenginyeria: Impresora 3D\, Organ-on-a-chip i CRISPR. Descobrirem aquestes tècniques les quals tots hem sentit a parlar i seran imprescindibles en un futur ben pròxim.\nTaula rodona i discussió informal amb joves bioenginyers i bioenginyeres. Tindrem la oportunitat de sentir l’experiència i compartir un pica-pica amb diferents perfils de doctorands i doctors en bioenginyeria. Des de la microscopia o l’optogenètica\, fins la indústria mèdica\, passant per la reprogramació cel·lular.\n\nQualsevol estudiant o professional amb motivacions per la Bioenginyeria serà més que benvingut. Amb una rigurositat científica ben estricte\, aquest esdeveniment està pensat per tots els estrats de biociències (estudiants de Grau\, estudiants de Màster i professionals del sector) \nAquest Workshop serà íntegrament en anglès. \n\nLloc: Sala Dolors Aleu\, Institut de Bioenginyeria de Catalunya (IBEC)\nData: 24 de Febrer de 2017\nHorari: 09h – 18h\n\nPreu: 5€ socis d’ASBTEC o membres de l’IBEC. 20€ no socis.\n15€ inscripció + associar-se a l’ASBTEC\nRegister at http://asbtec.blogspot.com.es/
URL:https://ibecbarcelona.eu/event/bioengineering-workshop-asbtec-ibec-2/
LOCATION:Sala Dolors Aleu\, Cluster II\, Parc Científic de Barcelona\, Barcelona\, Spain
CATEGORIES:Joint seminar / workshop / symposium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170216T100000
DTEND;TZID=Europe/Madrid:20170216T110000
DTSTAMP:20260405T175911
CREATED:20170213T100423Z
LAST-MODIFIED:20170213T100423Z
UID:95993-1487239200-1487242800@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Jesús Martínez de la Fuente
DESCRIPTION:Designing Hybrid Nanoparticles for Therapy and Diagnosis\nJesús Martínez de la Fuente\, Instituto de Ciencia de Materiales de Aragón\, CSIC/University of Zaragoza\nIn the last decades\, inorganic nanoparticles have been steadily gaining more attention from scientists from a wide variety of fields such as material science\, engineering\, physics or chemistry. The very different properties compared to that of the respective bulk\, and thus intriguing characteristics of materials in the nanometre scale\, have driven nanoscience to be the centre of many basic and applied research topics. Moreover\, a wide variety of recently developed methodologies for their surface functionalization provide these materials with very specific properties such as drug delivery and circulating cancer biomarkers detection. In this talk we describe the synthesis and functionalization of gold nanoparticles as therapeutic and diagnosis tools against cancer: \n-Pseudo-spherical gold nanoparticles derivatized with with fluorescent dyes\, cell penetrating peptides and small interfering RNA (siRNA) complementary to the proto-oncogene myc have been tested using a hierarchical approach including three biological systems of increasing complexity: in vitro cultured human cells\, in vivo invertebrate (freshwater polyp\, Hydra) and in vivo vertebrate (mouse) model. Selection of the most active functionalities was assisted step by step through functional testing adopting this hierarchical strategy.(1) Merging these chemical and biological approaches lead to a siRNA/RGD gold nanoparticle capable of targeting tumor cells in lung cancer xenograft mouse model\, resulting in successful and significant c-myc oncogene downregulation followed by tumor growth inhibition and prolonged survival of the animals.(2) \n-Gold nanoprisms (NPRs) have been functionalized with PEG\, glucose\, cell penetrating and RGD peptides\, antibodies and/or fluorescent dyes\, aiming to enhance NPRs stability\, cellular uptake and imaging capabilities\, respectively.(3) Cellular uptake and impact was assayed by a multiparametric investigation on the impact of surface modified NPRs on mice and human primary and transform cell lines. Under NIR illumination\, these nanoprobes can cause apoptosis. Moreover\, these nanoparticles have also been used for optoacoustic imaging and cancer treatment\,(4) as well as for tumoral marker detection using a novel type of thermal ELISA nanobiosensor using a thermosensitive support.(5) \nReferences\n[1] J. Conde\, A. Ambrosone\, V. Sanz\, Y. Hernandez\, F. Tian\, P. V. Baptista\, M. R. Ibarra\, C. Tortiglione\, J. M. de la Fuente. ACS Nano\, 2012\, 6\, 8316.\n[2] J. Conde\, F. Tian\, Y. Hernández\, C. Bao\, D. Cui\, M. R. Ibarra\, P. V. Baptista\, J. M. de la Fuente. Biomaterials. 2013\, 34\, 7744.\n[3] a) B. Pelaz\, V. Grazú\, A. Ibarra\, C. Magén\, P. del Pino\, J. M. de la Fuente. Langmuir\, 2012\, 28\, 8965 ; b) M. Perez-Hernandez\, P. del Pino\, S.G. Mitchell\, M. Moros\, G. Stepien\, B. Pelaz\, W.J. Parak\, E.M. Galvez\, J. Pardo\, J.M. de la Fuente. ACS Nano\, 2015\, 9\, 52\n[4] a) C. Bao\, N. Beziere\, P. del Pino\, B. Pelaz\, G. Estrada\, F. Tian\, V. Ntziachristos\, J. M. de la Fuente\, D. Cui. Small\, 2013\, 9\, 68 ; b) J. Han\, J. Zhang\, M. Yang\, D. Cui\, J.M. de la Fuente. Nanoscale\, 2016 (in press)\n[5] E. Polo\, P. del Pino\,  B. Pelaz\,  V. Grazu\, J.M. de la Fuente. Chemical Communications\, 2013\, 49\, 3676.
URL:https://ibecbarcelona.eu/event/ibec-seminar-jesus-martinez-de-la-fuente-4/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170216T100000
DTEND;TZID=Europe/Madrid:20170216T110000
DTSTAMP:20260405T175911
CREATED:20170213T100423Z
LAST-MODIFIED:20170214T123640Z
UID:27592-1487239200-1487242800@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Jesús Martínez de la Fuente
DESCRIPTION:Designing Hybrid Nanoparticles for Therapy and Diagnosis\nJesús Martínez de la Fuente\, Instituto de Ciencia de Materiales de Aragón\, CSIC/University of Zaragoza\nIn the last decades\, inorganic nanoparticles have been steadily gaining more attention from scientists from a wide variety of fields such as material science\, engineering\, physics or chemistry. The very different properties compared to that of the respective bulk\, and thus intriguing characteristics of materials in the nanometre scale\, have driven nanoscience to be the centre of many basic and applied research topics. Moreover\, a wide variety of recently developed methodologies for their surface functionalization provide these materials with very specific properties such as drug delivery and circulating cancer biomarkers detection. In this talk we describe the synthesis and functionalization of gold nanoparticles as therapeutic and diagnosis tools against cancer: \n-Pseudo-spherical gold nanoparticles derivatized with with fluorescent dyes\, cell penetrating peptides and small interfering RNA (siRNA) complementary to the proto-oncogene myc have been tested using a hierarchical approach including three biological systems of increasing complexity: in vitro cultured human cells\, in vivo invertebrate (freshwater polyp\, Hydra) and in vivo vertebrate (mouse) model. Selection of the most active functionalities was assisted step by step through functional testing adopting this hierarchical strategy.(1) Merging these chemical and biological approaches lead to a siRNA/RGD gold nanoparticle capable of targeting tumor cells in lung cancer xenograft mouse model\, resulting in successful and significant c-myc oncogene downregulation followed by tumor growth inhibition and prolonged survival of the animals.(2) \n-Gold nanoprisms (NPRs) have been functionalized with PEG\, glucose\, cell penetrating and RGD peptides\, antibodies and/or fluorescent dyes\, aiming to enhance NPRs stability\, cellular uptake and imaging capabilities\, respectively.(3) Cellular uptake and impact was assayed by a multiparametric investigation on the impact of surface modified NPRs on mice and human primary and transform cell lines. Under NIR illumination\, these nanoprobes can cause apoptosis. Moreover\, these nanoparticles have also been used for optoacoustic imaging and cancer treatment\,(4) as well as for tumoral marker detection using a novel type of thermal ELISA nanobiosensor using a thermosensitive support.(5) \nReferences\n[1] J. Conde\, A. Ambrosone\, V. Sanz\, Y. Hernandez\, F. Tian\, P. V. Baptista\, M. R. Ibarra\, C. Tortiglione\, J. M. de la Fuente. ACS Nano\, 2012\, 6\, 8316.\n[2] J. Conde\, F. Tian\, Y. Hernández\, C. Bao\, D. Cui\, M. R. Ibarra\, P. V. Baptista\, J. M. de la Fuente. Biomaterials. 2013\, 34\, 7744.\n[3] a) B. Pelaz\, V. Grazú\, A. Ibarra\, C. Magén\, P. del Pino\, J. M. de la Fuente. Langmuir\, 2012\, 28\, 8965 ; b) M. Perez-Hernandez\, P. del Pino\, S.G. Mitchell\, M. Moros\, G. Stepien\, B. Pelaz\, W.J. Parak\, E.M. Galvez\, J. Pardo\, J.M. de la Fuente. ACS Nano\, 2015\, 9\, 52\n[4] a) C. Bao\, N. Beziere\, P. del Pino\, B. Pelaz\, G. Estrada\, F. Tian\, V. Ntziachristos\, J. M. de la Fuente\, D. Cui. Small\, 2013\, 9\, 68 ; b) J. Han\, J. Zhang\, M. Yang\, D. Cui\, J.M. de la Fuente. Nanoscale\, 2016 (in press)\n[5] E. Polo\, P. del Pino\,  B. Pelaz\,  V. Grazu\, J.M. de la Fuente. Chemical Communications\, 2013\, 49\, 3676.
URL:https://ibecbarcelona.eu/event/ibec-seminar-jesus-martinez-de-la-fuente/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170216T100000
DTEND;TZID=Europe/Madrid:20170216T110000
DTSTAMP:20260405T175911
CREATED:20170213T100423Z
LAST-MODIFIED:20170213T100423Z
UID:95987-1487239200-1487242800@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Jesús Martínez de la Fuente
DESCRIPTION:Designing Hybrid Nanoparticles for Therapy and Diagnosis\nJesús Martínez de la Fuente\, Instituto de Ciencia de Materiales de Aragón\, CSIC/University of Zaragoza\nIn the last decades\, inorganic nanoparticles have been steadily gaining more attention from scientists from a wide variety of fields such as material science\, engineering\, physics or chemistry. The very different properties compared to that of the respective bulk\, and thus intriguing characteristics of materials in the nanometre scale\, have driven nanoscience to be the centre of many basic and applied research topics. Moreover\, a wide variety of recently developed methodologies for their surface functionalization provide these materials with very specific properties such as drug delivery and circulating cancer biomarkers detection. In this talk we describe the synthesis and functionalization of gold nanoparticles as therapeutic and diagnosis tools against cancer: \n-Pseudo-spherical gold nanoparticles derivatized with with fluorescent dyes\, cell penetrating peptides and small interfering RNA (siRNA) complementary to the proto-oncogene myc have been tested using a hierarchical approach including three biological systems of increasing complexity: in vitro cultured human cells\, in vivo invertebrate (freshwater polyp\, Hydra) and in vivo vertebrate (mouse) model. Selection of the most active functionalities was assisted step by step through functional testing adopting this hierarchical strategy.(1) Merging these chemical and biological approaches lead to a siRNA/RGD gold nanoparticle capable of targeting tumor cells in lung cancer xenograft mouse model\, resulting in successful and significant c-myc oncogene downregulation followed by tumor growth inhibition and prolonged survival of the animals.(2) \n-Gold nanoprisms (NPRs) have been functionalized with PEG\, glucose\, cell penetrating and RGD peptides\, antibodies and/or fluorescent dyes\, aiming to enhance NPRs stability\, cellular uptake and imaging capabilities\, respectively.(3) Cellular uptake and impact was assayed by a multiparametric investigation on the impact of surface modified NPRs on mice and human primary and transform cell lines. Under NIR illumination\, these nanoprobes can cause apoptosis. Moreover\, these nanoparticles have also been used for optoacoustic imaging and cancer treatment\,(4) as well as for tumoral marker detection using a novel type of thermal ELISA nanobiosensor using a thermosensitive support.(5) \nReferences\n[1] J. Conde\, A. Ambrosone\, V. Sanz\, Y. Hernandez\, F. Tian\, P. V. Baptista\, M. R. Ibarra\, C. Tortiglione\, J. M. de la Fuente. ACS Nano\, 2012\, 6\, 8316.\n[2] J. Conde\, F. Tian\, Y. Hernández\, C. Bao\, D. Cui\, M. R. Ibarra\, P. V. Baptista\, J. M. de la Fuente. Biomaterials. 2013\, 34\, 7744.\n[3] a) B. Pelaz\, V. Grazú\, A. Ibarra\, C. Magén\, P. del Pino\, J. M. de la Fuente. Langmuir\, 2012\, 28\, 8965 ; b) M. Perez-Hernandez\, P. del Pino\, S.G. Mitchell\, M. Moros\, G. Stepien\, B. Pelaz\, W.J. Parak\, E.M. Galvez\, J. Pardo\, J.M. de la Fuente. ACS Nano\, 2015\, 9\, 52\n[4] a) C. Bao\, N. Beziere\, P. del Pino\, B. Pelaz\, G. Estrada\, F. Tian\, V. Ntziachristos\, J. M. de la Fuente\, D. Cui. Small\, 2013\, 9\, 68 ; b) J. Han\, J. Zhang\, M. Yang\, D. Cui\, J.M. de la Fuente. Nanoscale\, 2016 (in press)\n[5] E. Polo\, P. del Pino\,  B. Pelaz\,  V. Grazu\, J.M. de la Fuente. Chemical Communications\, 2013\, 49\, 3676.
URL:https://ibecbarcelona.eu/event/ibec-seminar-jesus-martinez-de-la-fuente-2/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170216T100000
DTEND;TZID=Europe/Madrid:20170216T110000
DTSTAMP:20260405T175911
CREATED:20170213T100423Z
LAST-MODIFIED:20170213T100423Z
UID:95992-1487239200-1487242800@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Jesús Martínez de la Fuente
DESCRIPTION:Designing Hybrid Nanoparticles for Therapy and Diagnosis\nJesús Martínez de la Fuente\, Instituto de Ciencia de Materiales de Aragón\, CSIC/University of Zaragoza\nIn the last decades\, inorganic nanoparticles have been steadily gaining more attention from scientists from a wide variety of fields such as material science\, engineering\, physics or chemistry. The very different properties compared to that of the respective bulk\, and thus intriguing characteristics of materials in the nanometre scale\, have driven nanoscience to be the centre of many basic and applied research topics. Moreover\, a wide variety of recently developed methodologies for their surface functionalization provide these materials with very specific properties such as drug delivery and circulating cancer biomarkers detection. In this talk we describe the synthesis and functionalization of gold nanoparticles as therapeutic and diagnosis tools against cancer: \n-Pseudo-spherical gold nanoparticles derivatized with with fluorescent dyes\, cell penetrating peptides and small interfering RNA (siRNA) complementary to the proto-oncogene myc have been tested using a hierarchical approach including three biological systems of increasing complexity: in vitro cultured human cells\, in vivo invertebrate (freshwater polyp\, Hydra) and in vivo vertebrate (mouse) model. Selection of the most active functionalities was assisted step by step through functional testing adopting this hierarchical strategy.(1) Merging these chemical and biological approaches lead to a siRNA/RGD gold nanoparticle capable of targeting tumor cells in lung cancer xenograft mouse model\, resulting in successful and significant c-myc oncogene downregulation followed by tumor growth inhibition and prolonged survival of the animals.(2) \n-Gold nanoprisms (NPRs) have been functionalized with PEG\, glucose\, cell penetrating and RGD peptides\, antibodies and/or fluorescent dyes\, aiming to enhance NPRs stability\, cellular uptake and imaging capabilities\, respectively.(3) Cellular uptake and impact was assayed by a multiparametric investigation on the impact of surface modified NPRs on mice and human primary and transform cell lines. Under NIR illumination\, these nanoprobes can cause apoptosis. Moreover\, these nanoparticles have also been used for optoacoustic imaging and cancer treatment\,(4) as well as for tumoral marker detection using a novel type of thermal ELISA nanobiosensor using a thermosensitive support.(5) \nReferences\n[1] J. Conde\, A. Ambrosone\, V. Sanz\, Y. Hernandez\, F. Tian\, P. V. Baptista\, M. R. Ibarra\, C. Tortiglione\, J. M. de la Fuente. ACS Nano\, 2012\, 6\, 8316.\n[2] J. Conde\, F. Tian\, Y. Hernández\, C. Bao\, D. Cui\, M. R. Ibarra\, P. V. Baptista\, J. M. de la Fuente. Biomaterials. 2013\, 34\, 7744.\n[3] a) B. Pelaz\, V. Grazú\, A. Ibarra\, C. Magén\, P. del Pino\, J. M. de la Fuente. Langmuir\, 2012\, 28\, 8965 ; b) M. Perez-Hernandez\, P. del Pino\, S.G. Mitchell\, M. Moros\, G. Stepien\, B. Pelaz\, W.J. Parak\, E.M. Galvez\, J. Pardo\, J.M. de la Fuente. ACS Nano\, 2015\, 9\, 52\n[4] a) C. Bao\, N. Beziere\, P. del Pino\, B. Pelaz\, G. Estrada\, F. Tian\, V. Ntziachristos\, J. M. de la Fuente\, D. Cui. Small\, 2013\, 9\, 68 ; b) J. Han\, J. Zhang\, M. Yang\, D. Cui\, J.M. de la Fuente. Nanoscale\, 2016 (in press)\n[5] E. Polo\, P. del Pino\,  B. Pelaz\,  V. Grazu\, J.M. de la Fuente. Chemical Communications\, 2013\, 49\, 3676.
URL:https://ibecbarcelona.eu/event/ibec-seminar-jesus-martinez-de-la-fuente-3/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170210T100000
DTEND;TZID=Europe/Madrid:20170210T110000
DTSTAMP:20260405T175911
CREATED:20170202T092723Z
LAST-MODIFIED:20170202T092723Z
UID:95980-1486720800-1486724400@ibecbarcelona.eu
SUMMARY:IBEC PhD Discussions Sessions: Elisabeth Pain
DESCRIPTION:Planning your academic career with an open mind\nElisabeth Pain\, Contributing Editor for Science Careers\, Europe\nAcademic careers are very competitive these days and the decisions you make as a PhD. student can greatly influence your chances of success. Choosing a good postdoc is particularly important\, as the experience should help you develop new skills and knowledge but also a name for yourself. When should you start looking for a postdoc? What aspects should you consider? When are postdocs too many? What are the alternatives? In this session\, we will explore how to plan your academic career ahead while keeping an open mind on other possible opportunities.
URL:https://ibecbarcelona.eu/event/ibec-phd-discussions-sessions-elisabeth-pain-2/
CATEGORIES:PhD Discussions Complementary Skills Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170210T100000
DTEND;TZID=Europe/Madrid:20170210T110000
DTSTAMP:20260405T175911
CREATED:20170202T092723Z
LAST-MODIFIED:20170202T092723Z
UID:95981-1486720800-1486724400@ibecbarcelona.eu
SUMMARY:IBEC PhD Discussions Sessions: Elisabeth Pain
DESCRIPTION:Planning your academic career with an open mind\nElisabeth Pain\, Contributing Editor for Science Careers\, Europe\nAcademic careers are very competitive these days and the decisions you make as a PhD. student can greatly influence your chances of success. Choosing a good postdoc is particularly important\, as the experience should help you develop new skills and knowledge but also a name for yourself. When should you start looking for a postdoc? What aspects should you consider? When are postdocs too many? What are the alternatives? In this session\, we will explore how to plan your academic career ahead while keeping an open mind on other possible opportunities.
URL:https://ibecbarcelona.eu/event/ibec-phd-discussions-sessions-elisabeth-pain-3/
CATEGORIES:PhD Discussions Complementary Skills Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170210T100000
DTEND;TZID=Europe/Madrid:20170210T110000
DTSTAMP:20260405T175911
CREATED:20170202T092723Z
LAST-MODIFIED:20170202T092723Z
UID:95982-1486720800-1486724400@ibecbarcelona.eu
SUMMARY:IBEC PhD Discussions Sessions: Elisabeth Pain
DESCRIPTION:Planning your academic career with an open mind\nElisabeth Pain\, Contributing Editor for Science Careers\, Europe\nAcademic careers are very competitive these days and the decisions you make as a PhD. student can greatly influence your chances of success. Choosing a good postdoc is particularly important\, as the experience should help you develop new skills and knowledge but also a name for yourself. When should you start looking for a postdoc? What aspects should you consider? When are postdocs too many? What are the alternatives? In this session\, we will explore how to plan your academic career ahead while keeping an open mind on other possible opportunities.
URL:https://ibecbarcelona.eu/event/ibec-phd-discussions-sessions-elisabeth-pain-4/
CATEGORIES:PhD Discussions Complementary Skills Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170210T100000
DTEND;TZID=Europe/Madrid:20170210T110000
DTSTAMP:20260405T175911
CREATED:20170202T092723Z
LAST-MODIFIED:20170202T092723Z
UID:27402-1486720800-1486724400@ibecbarcelona.eu
SUMMARY:IBEC PhD Discussions Sessions: Elisabeth Pain
DESCRIPTION:Planning your academic career with an open mind\nElisabeth Pain\, Contributing Editor for Science Careers\, Europe\nAcademic careers are very competitive these days and the decisions you make as a PhD. student can greatly influence your chances of success. Choosing a good postdoc is particularly important\, as the experience should help you develop new skills and knowledge but also a name for yourself. When should you start looking for a postdoc? What aspects should you consider? When are postdocs too many? What are the alternatives? In this session\, we will explore how to plan your academic career ahead while keeping an open mind on other possible opportunities.
URL:https://ibecbarcelona.eu/event/ibec-phd-discussions-sessions-elisabeth-pain/
CATEGORIES:PhD Discussions Complementary Skills Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170208T120000
DTEND;TZID=Europe/Madrid:20170208T130000
DTSTAMP:20260405T175911
CREATED:20170203T102730Z
LAST-MODIFIED:20170203T102730Z
UID:95985-1486555200-1486558800@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Stijn Mertens
DESCRIPTION:Electrochemical surface science of TiO2 rutile (110)\, graphene and boron nitride\nStijn Mertens\, TU Wien\, Institute of Applied Physics / KU Leuven\, Chemistry Department\nThe rational design of catalysts and other functional materials requires an atomic-level understanding of their structure and of the interface to supporting surfaces. I will present an in situ electrochemical STM study of TiO2 rutile (110) with atomic resolution. This is achieved using a new wet-chemical cleaning procedure for the substrate and with Pt-Ir tips. If tungsten tips are used\, WO3 is spontaneously formed at the tungsten–liquid interface and strongly adsorbs on oxide surfaces below their point of zero charge through an electrostatic mechanism. Under clean conditions\, the TiO2 rutile (110) surface shows a bulk-like\, unreconstructed structure\, which resembles its appearance in vacuum\, even though the surface is probably fully hydroxylated. \nIn the second part of my talk\, I will focus on 2D materials graphene and hexagonal boron nitride. By combining electrochemical grafting of diazonium salts with tip-induced nanolithography\, nanopatterned sp3 defects can be introduced\, opening perspectives towards graphene band gap engineering [1\,2]. Hexagonal boron nitride\, isoelectronic with graphene\, can be grown on Rh(111) and forms a so-called nanomesh superstructure [3]\, characterized by a 3.2-nm lattice constant and strong electronic corrugation\, useful for trapping atoms and molecules. Electrochemical intercalation of hydrogen between the boron nitride layer and the rhodium substrate leads to microscopic flattening within the 2-dimensional material and a macroscopic 10% change in adsorption energy [4]. \n[1] Greenwood et al.\, ACS Nano 9\, 2015\, 5520.\n[2] Huynh et al.\, Nanoscale 9\, 2017\, 362.\n[3] Corso et al.\, Science 303\, 2004\, 217.\n[4] Mertens et al.\, Nature 534\, 2016\, 676.
URL:https://ibecbarcelona.eu/event/ibec-seminar-stijn-mertens-3/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170208T120000
DTEND;TZID=Europe/Madrid:20170208T130000
DTSTAMP:20260405T175911
CREATED:20170203T102730Z
LAST-MODIFIED:20170203T102730Z
UID:95986-1486555200-1486558800@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Stijn Mertens
DESCRIPTION:Electrochemical surface science of TiO2 rutile (110)\, graphene and boron nitride\nStijn Mertens\, TU Wien\, Institute of Applied Physics / KU Leuven\, Chemistry Department\nThe rational design of catalysts and other functional materials requires an atomic-level understanding of their structure and of the interface to supporting surfaces. I will present an in situ electrochemical STM study of TiO2 rutile (110) with atomic resolution. This is achieved using a new wet-chemical cleaning procedure for the substrate and with Pt-Ir tips. If tungsten tips are used\, WO3 is spontaneously formed at the tungsten–liquid interface and strongly adsorbs on oxide surfaces below their point of zero charge through an electrostatic mechanism. Under clean conditions\, the TiO2 rutile (110) surface shows a bulk-like\, unreconstructed structure\, which resembles its appearance in vacuum\, even though the surface is probably fully hydroxylated. \nIn the second part of my talk\, I will focus on 2D materials graphene and hexagonal boron nitride. By combining electrochemical grafting of diazonium salts with tip-induced nanolithography\, nanopatterned sp3 defects can be introduced\, opening perspectives towards graphene band gap engineering [1\,2]. Hexagonal boron nitride\, isoelectronic with graphene\, can be grown on Rh(111) and forms a so-called nanomesh superstructure [3]\, characterized by a 3.2-nm lattice constant and strong electronic corrugation\, useful for trapping atoms and molecules. Electrochemical intercalation of hydrogen between the boron nitride layer and the rhodium substrate leads to microscopic flattening within the 2-dimensional material and a macroscopic 10% change in adsorption energy [4]. \n[1] Greenwood et al.\, ACS Nano 9\, 2015\, 5520.\n[2] Huynh et al.\, Nanoscale 9\, 2017\, 362.\n[3] Corso et al.\, Science 303\, 2004\, 217.\n[4] Mertens et al.\, Nature 534\, 2016\, 676.
URL:https://ibecbarcelona.eu/event/ibec-seminar-stijn-mertens-4/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170208T120000
DTEND;TZID=Europe/Madrid:20170208T130000
DTSTAMP:20260405T175911
CREATED:20170203T102730Z
LAST-MODIFIED:20170213T120656Z
UID:27427-1486555200-1486558800@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Stijn Mertens
DESCRIPTION:Electrochemical surface science of TiO2 rutile (110)\, graphene and boron nitride\nStijn Mertens\, TU Wien\, Institute of Applied Physics / KU Leuven\, Chemistry Department\nThe rational design of catalysts and other functional materials requires an atomic-level understanding of their structure and of the interface to supporting surfaces. I will present an in situ electrochemical STM study of TiO2 rutile (110) with atomic resolution. This is achieved using a new wet-chemical cleaning procedure for the substrate and with Pt-Ir tips. If tungsten tips are used\, WO3 is spontaneously formed at the tungsten–liquid interface and strongly adsorbs on oxide surfaces below their point of zero charge through an electrostatic mechanism. Under clean conditions\, the TiO2 rutile (110) surface shows a bulk-like\, unreconstructed structure\, which resembles its appearance in vacuum\, even though the surface is probably fully hydroxylated. \nIn the second part of my talk\, I will focus on 2D materials graphene and hexagonal boron nitride. By combining electrochemical grafting of diazonium salts with tip-induced nanolithography\, nanopatterned sp3 defects can be introduced\, opening perspectives towards graphene band gap engineering [1\,2]. Hexagonal boron nitride\, isoelectronic with graphene\, can be grown on Rh(111) and forms a so-called nanomesh superstructure [3]\, characterized by a 3.2-nm lattice constant and strong electronic corrugation\, useful for trapping atoms and molecules. Electrochemical intercalation of hydrogen between the boron nitride layer and the rhodium substrate leads to microscopic flattening within the 2-dimensional material and a macroscopic 10% change in adsorption energy [4]. \n[1] Greenwood et al.\, ACS Nano 9\, 2015\, 5520.\n[2] Huynh et al.\, Nanoscale 9\, 2017\, 362.\n[3] Corso et al.\, Science 303\, 2004\, 217.\n[4] Mertens et al.\, Nature 534\, 2016\, 676.
URL:https://ibecbarcelona.eu/event/ibec-seminar-stijn-mertens/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170208T120000
DTEND;TZID=Europe/Madrid:20170208T130000
DTSTAMP:20260405T175911
CREATED:20170203T102730Z
LAST-MODIFIED:20170203T102730Z
UID:95984-1486555200-1486558800@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Stijn Mertens
DESCRIPTION:Electrochemical surface science of TiO2 rutile (110)\, graphene and boron nitride\nStijn Mertens\, TU Wien\, Institute of Applied Physics / KU Leuven\, Chemistry Department\nThe rational design of catalysts and other functional materials requires an atomic-level understanding of their structure and of the interface to supporting surfaces. I will present an in situ electrochemical STM study of TiO2 rutile (110) with atomic resolution. This is achieved using a new wet-chemical cleaning procedure for the substrate and with Pt-Ir tips. If tungsten tips are used\, WO3 is spontaneously formed at the tungsten–liquid interface and strongly adsorbs on oxide surfaces below their point of zero charge through an electrostatic mechanism. Under clean conditions\, the TiO2 rutile (110) surface shows a bulk-like\, unreconstructed structure\, which resembles its appearance in vacuum\, even though the surface is probably fully hydroxylated. \nIn the second part of my talk\, I will focus on 2D materials graphene and hexagonal boron nitride. By combining electrochemical grafting of diazonium salts with tip-induced nanolithography\, nanopatterned sp3 defects can be introduced\, opening perspectives towards graphene band gap engineering [1\,2]. Hexagonal boron nitride\, isoelectronic with graphene\, can be grown on Rh(111) and forms a so-called nanomesh superstructure [3]\, characterized by a 3.2-nm lattice constant and strong electronic corrugation\, useful for trapping atoms and molecules. Electrochemical intercalation of hydrogen between the boron nitride layer and the rhodium substrate leads to microscopic flattening within the 2-dimensional material and a macroscopic 10% change in adsorption energy [4]. \n[1] Greenwood et al.\, ACS Nano 9\, 2015\, 5520.\n[2] Huynh et al.\, Nanoscale 9\, 2017\, 362.\n[3] Corso et al.\, Science 303\, 2004\, 217.\n[4] Mertens et al.\, Nature 534\, 2016\, 676.
URL:https://ibecbarcelona.eu/event/ibec-seminar-stijn-mertens-2/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170203T100000
DTEND;TZID=Europe/Madrid:20170203T110000
DTSTAMP:20260405T175911
CREATED:20170202T075031Z
LAST-MODIFIED:20170202T075031Z
UID:95975-1486116000-1486119600@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Giuseppe Battaglia
DESCRIPTION:Bionic nanoscopic carriers for precision drug delivery\nGiuseppe Battaglia\, Department of Chemistry and Department of Chemical Engineering\, University College London\nGetting across biological barriers and deliver therapeutic cargo to the right site is indeed a very challenging task that requires the judicious combination of physiological information with carrier engineering. In the last decade\, we have approached this problem\, applying a constructionist approach where we mimic biological complexity in the form of design principles to produce functional bionic units from simple building blocks and their interactions. We combine synthetic and supramolecular chemistry to tune inter/intramolecular interactions and self-assembly processes to form dynamic soft materials. Among the different bionic efforts\, we have focussed our attention to possibly one of the few that encompasses polymerisation\, compartmentalisation and positional self-assembly in the same unit; Polymersomes. These are vesicles formed by the self-assembly of amphiphilic block copolymers in water. We have equipped polymersomes with the critical elements to address the challenges for getting across biological barriers. They have surface engineered to control both attractive (binding) and repulsive (anti-fouling) interaction with proteins and receptors to create systems that can avoid opsonisation and yet target specific cell populations. We have engineered their mechanical properties so as to be flexible and able to penetrate dense tissues exploiting size-exclusion percolation patterns. We have equipped them with both asymmetric topology and enzymes to control their fluid-dynamics and diffusion so as to create chemotactic and active propulsion toward endogenous signalling molecules. Finally\, we have engineered their shape and size to guide cellular endocytosis as well as to escape the endocytic sorting accessing and delivering cargo within the cell interior. \nI will present our design efforts discussing each structural and functional elements as a function of the respective biological challenge\, I will conclude presenting applications where these precision systems are being applied to address challenges in oncology\, immunology and neurology.
URL:https://ibecbarcelona.eu/event/ibec-seminar-giuseppe-battaglia-2/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170203T100000
DTEND;TZID=Europe/Madrid:20170203T110000
DTSTAMP:20260405T175911
CREATED:20170202T075031Z
LAST-MODIFIED:20170202T075031Z
UID:95976-1486116000-1486119600@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Giuseppe Battaglia
DESCRIPTION:Bionic nanoscopic carriers for precision drug delivery\nGiuseppe Battaglia\, Department of Chemistry and Department of Chemical Engineering\, University College London\nGetting across biological barriers and deliver therapeutic cargo to the right site is indeed a very challenging task that requires the judicious combination of physiological information with carrier engineering. In the last decade\, we have approached this problem\, applying a constructionist approach where we mimic biological complexity in the form of design principles to produce functional bionic units from simple building blocks and their interactions. We combine synthetic and supramolecular chemistry to tune inter/intramolecular interactions and self-assembly processes to form dynamic soft materials. Among the different bionic efforts\, we have focussed our attention to possibly one of the few that encompasses polymerisation\, compartmentalisation and positional self-assembly in the same unit; Polymersomes. These are vesicles formed by the self-assembly of amphiphilic block copolymers in water. We have equipped polymersomes with the critical elements to address the challenges for getting across biological barriers. They have surface engineered to control both attractive (binding) and repulsive (anti-fouling) interaction with proteins and receptors to create systems that can avoid opsonisation and yet target specific cell populations. We have engineered their mechanical properties so as to be flexible and able to penetrate dense tissues exploiting size-exclusion percolation patterns. We have equipped them with both asymmetric topology and enzymes to control their fluid-dynamics and diffusion so as to create chemotactic and active propulsion toward endogenous signalling molecules. Finally\, we have engineered their shape and size to guide cellular endocytosis as well as to escape the endocytic sorting accessing and delivering cargo within the cell interior. \nI will present our design efforts discussing each structural and functional elements as a function of the respective biological challenge\, I will conclude presenting applications where these precision systems are being applied to address challenges in oncology\, immunology and neurology.
URL:https://ibecbarcelona.eu/event/ibec-seminar-giuseppe-battaglia-3/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170203T100000
DTEND;TZID=Europe/Madrid:20170203T110000
DTSTAMP:20260405T175911
CREATED:20170202T075031Z
LAST-MODIFIED:20170202T075031Z
UID:95977-1486116000-1486119600@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Giuseppe Battaglia
DESCRIPTION:Bionic nanoscopic carriers for precision drug delivery\nGiuseppe Battaglia\, Department of Chemistry and Department of Chemical Engineering\, University College London\nGetting across biological barriers and deliver therapeutic cargo to the right site is indeed a very challenging task that requires the judicious combination of physiological information with carrier engineering. In the last decade\, we have approached this problem\, applying a constructionist approach where we mimic biological complexity in the form of design principles to produce functional bionic units from simple building blocks and their interactions. We combine synthetic and supramolecular chemistry to tune inter/intramolecular interactions and self-assembly processes to form dynamic soft materials. Among the different bionic efforts\, we have focussed our attention to possibly one of the few that encompasses polymerisation\, compartmentalisation and positional self-assembly in the same unit; Polymersomes. These are vesicles formed by the self-assembly of amphiphilic block copolymers in water. We have equipped polymersomes with the critical elements to address the challenges for getting across biological barriers. They have surface engineered to control both attractive (binding) and repulsive (anti-fouling) interaction with proteins and receptors to create systems that can avoid opsonisation and yet target specific cell populations. We have engineered their mechanical properties so as to be flexible and able to penetrate dense tissues exploiting size-exclusion percolation patterns. We have equipped them with both asymmetric topology and enzymes to control their fluid-dynamics and diffusion so as to create chemotactic and active propulsion toward endogenous signalling molecules. Finally\, we have engineered their shape and size to guide cellular endocytosis as well as to escape the endocytic sorting accessing and delivering cargo within the cell interior. \nI will present our design efforts discussing each structural and functional elements as a function of the respective biological challenge\, I will conclude presenting applications where these precision systems are being applied to address challenges in oncology\, immunology and neurology.
URL:https://ibecbarcelona.eu/event/ibec-seminar-giuseppe-battaglia-4/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170203T100000
DTEND;TZID=Europe/Madrid:20170203T110000
DTSTAMP:20260405T175911
CREATED:20170202T075031Z
LAST-MODIFIED:20170202T075031Z
UID:27390-1486116000-1486119600@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Giuseppe Battaglia
DESCRIPTION:Bionic nanoscopic carriers for precision drug delivery\nGiuseppe Battaglia\, Department of Chemistry and Department of Chemical Engineering\, University College London\nGetting across biological barriers and deliver therapeutic cargo to the right site is indeed a very challenging task that requires the judicious combination of physiological information with carrier engineering. In the last decade\, we have approached this problem\, applying a constructionist approach where we mimic biological complexity in the form of design principles to produce functional bionic units from simple building blocks and their interactions. We combine synthetic and supramolecular chemistry to tune inter/intramolecular interactions and self-assembly processes to form dynamic soft materials. Among the different bionic efforts\, we have focussed our attention to possibly one of the few that encompasses polymerisation\, compartmentalisation and positional self-assembly in the same unit; Polymersomes. These are vesicles formed by the self-assembly of amphiphilic block copolymers in water. We have equipped polymersomes with the critical elements to address the challenges for getting across biological barriers. They have surface engineered to control both attractive (binding) and repulsive (anti-fouling) interaction with proteins and receptors to create systems that can avoid opsonisation and yet target specific cell populations. We have engineered their mechanical properties so as to be flexible and able to penetrate dense tissues exploiting size-exclusion percolation patterns. We have equipped them with both asymmetric topology and enzymes to control their fluid-dynamics and diffusion so as to create chemotactic and active propulsion toward endogenous signalling molecules. Finally\, we have engineered their shape and size to guide cellular endocytosis as well as to escape the endocytic sorting accessing and delivering cargo within the cell interior. \nI will present our design efforts discussing each structural and functional elements as a function of the respective biological challenge\, I will conclude presenting applications where these precision systems are being applied to address challenges in oncology\, immunology and neurology.
URL:https://ibecbarcelona.eu/event/ibec-seminar-giuseppe-battaglia/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170202T080000
DTEND;TZID=Europe/Madrid:20170202T170000
DTSTAMP:20260405T175911
CREATED:20170112T091424Z
LAST-MODIFIED:20170112T091424Z
UID:95978-1486022400-1486054800@ibecbarcelona.eu
SUMMARY:Nano World Cancer Day 2017
DESCRIPTION: \n \nBienvenido al NANO WORLD CANCER DAY 2017!\nEl próximo 2 de febrero se celebrará la cuarta edición del NANO WORLD CANCER DAY (NWCD)\, un evento de alcance mundial organizado en el marco del Día Mundial del Cáncer. Su principal objetivo es dar a conocer las últimas innovaciones en materia de nanomedicina contra el cáncer\, con temas que van desde el diagnóstico precoz\, la liberación controlada de fármacos o la radioterapia con nanopartículas. \nDurante el NANO WORLD CANCER DAY 2017 se organizarán eventos simultáneos en diferentes países de toda Europa\, con la presencia de la prensa. Este año los países participantes en el acontecimiento internacional serán: Alemania\, Austria\, Francia\, Grecia\, Irlanda\, Italia\, Países Bajos\, Portugal\, España\, Suiza\, Turquía y Reino Unido.\nDurante este día\, expertos en Nanomedicina de cada país\, y desde los diferentes campos (investigadores\, médicos\, oncólogos\, emprendedores\, etc.) expondrán los últimos adelantos y nos darán la oportunidad de descubrir el generador de progreso que la Nanomedicina significa para la salud como creador de nuevas oportunidades en el diagnóstico y el tratamiento del cáncer. \nNANO WORLD CANCER DAY es un evento que se inició en 2013 y está organizado a nivel europeo por  ETP Nanomedicine (European Technology Platform)\, en el marco del proyecto europeo ENATRANS (Enabling Nanomodicine Translation)\, y de manera local por los diferentes componentes de la plataforma en cada país\, en España\, NanomedSpain. \n 
URL:https://ibecbarcelona.eu/event/nano-world-cancer-day-2017-barcelona-3/
LOCATION:Vall d’Hebron\, Barcelona\, Spain
CATEGORIES:External symposium / conference / congress
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170202T080000
DTEND;TZID=Europe/Madrid:20170202T170000
DTSTAMP:20260405T175911
CREATED:20170112T091424Z
LAST-MODIFIED:20170112T091424Z
UID:95979-1486022400-1486054800@ibecbarcelona.eu
SUMMARY:Nano World Cancer Day 2017
DESCRIPTION: \n \nBienvenido al NANO WORLD CANCER DAY 2017!\nEl próximo 2 de febrero se celebrará la cuarta edición del NANO WORLD CANCER DAY (NWCD)\, un evento de alcance mundial organizado en el marco del Día Mundial del Cáncer. Su principal objetivo es dar a conocer las últimas innovaciones en materia de nanomedicina contra el cáncer\, con temas que van desde el diagnóstico precoz\, la liberación controlada de fármacos o la radioterapia con nanopartículas. \nDurante el NANO WORLD CANCER DAY 2017 se organizarán eventos simultáneos en diferentes países de toda Europa\, con la presencia de la prensa. Este año los países participantes en el acontecimiento internacional serán: Alemania\, Austria\, Francia\, Grecia\, Irlanda\, Italia\, Países Bajos\, Portugal\, España\, Suiza\, Turquía y Reino Unido.\nDurante este día\, expertos en Nanomedicina de cada país\, y desde los diferentes campos (investigadores\, médicos\, oncólogos\, emprendedores\, etc.) expondrán los últimos adelantos y nos darán la oportunidad de descubrir el generador de progreso que la Nanomedicina significa para la salud como creador de nuevas oportunidades en el diagnóstico y el tratamiento del cáncer. \nNANO WORLD CANCER DAY es un evento que se inició en 2013 y está organizado a nivel europeo por  ETP Nanomedicine (European Technology Platform)\, en el marco del proyecto europeo ENATRANS (Enabling Nanomodicine Translation)\, y de manera local por los diferentes componentes de la plataforma en cada país\, en España\, NanomedSpain. \n 
URL:https://ibecbarcelona.eu/event/nano-world-cancer-day-2017-barcelona-4/
LOCATION:Vall d’Hebron\, Barcelona\, Spain
CATEGORIES:External symposium / conference / congress
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170202T080000
DTEND;TZID=Europe/Madrid:20170202T170000
DTSTAMP:20260405T175911
CREATED:20170112T091424Z
LAST-MODIFIED:20170801T110457Z
UID:27062-1486022400-1486054800@ibecbarcelona.eu
SUMMARY:Nano World Cancer Day 2017
DESCRIPTION: \n \nBienvenido al NANO WORLD CANCER DAY 2017!\nEl próximo 2 de febrero se celebrará la cuarta edición del NANO WORLD CANCER DAY (NWCD)\, un evento de alcance mundial organizado en el marco del Día Mundial del Cáncer. Su principal objetivo es dar a conocer las últimas innovaciones en materia de nanomedicina contra el cáncer\, con temas que van desde el diagnóstico precoz\, la liberación controlada de fármacos o la radioterapia con nanopartículas. \nDurante el NANO WORLD CANCER DAY 2017 se organizarán eventos simultáneos en diferentes países de toda Europa\, con la presencia de la prensa. Este año los países participantes en el acontecimiento internacional serán: Alemania\, Austria\, Francia\, Grecia\, Irlanda\, Italia\, Países Bajos\, Portugal\, España\, Suiza\, Turquía y Reino Unido.\nDurante este día\, expertos en Nanomedicina de cada país\, y desde los diferentes campos (investigadores\, médicos\, oncólogos\, emprendedores\, etc.) expondrán los últimos adelantos y nos darán la oportunidad de descubrir el generador de progreso que la Nanomedicina significa para la salud como creador de nuevas oportunidades en el diagnóstico y el tratamiento del cáncer. \nNANO WORLD CANCER DAY es un evento que se inició en 2013 y está organizado a nivel europeo por  ETP Nanomedicine (European Technology Platform)\, en el marco del proyecto europeo ENATRANS (Enabling Nanomodicine Translation)\, y de manera local por los diferentes componentes de la plataforma en cada país\, en España\, NanomedSpain. \n 
URL:https://ibecbarcelona.eu/event/nano-world-cancer-day-2017-barcelona/
LOCATION:Vall d’Hebron\, Barcelona\, Spain
CATEGORIES:External symposium / conference / congress
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170202T080000
DTEND;TZID=Europe/Madrid:20170202T170000
DTSTAMP:20260405T175911
CREATED:20170112T091424Z
LAST-MODIFIED:20170112T091424Z
UID:95967-1486022400-1486054800@ibecbarcelona.eu
SUMMARY:Nano World Cancer Day 2017
DESCRIPTION: \n \nBienvenido al NANO WORLD CANCER DAY 2017!\nEl próximo 2 de febrero se celebrará la cuarta edición del NANO WORLD CANCER DAY (NWCD)\, un evento de alcance mundial organizado en el marco del Día Mundial del Cáncer. Su principal objetivo es dar a conocer las últimas innovaciones en materia de nanomedicina contra el cáncer\, con temas que van desde el diagnóstico precoz\, la liberación controlada de fármacos o la radioterapia con nanopartículas. \nDurante el NANO WORLD CANCER DAY 2017 se organizarán eventos simultáneos en diferentes países de toda Europa\, con la presencia de la prensa. Este año los países participantes en el acontecimiento internacional serán: Alemania\, Austria\, Francia\, Grecia\, Irlanda\, Italia\, Países Bajos\, Portugal\, España\, Suiza\, Turquía y Reino Unido.\nDurante este día\, expertos en Nanomedicina de cada país\, y desde los diferentes campos (investigadores\, médicos\, oncólogos\, emprendedores\, etc.) expondrán los últimos adelantos y nos darán la oportunidad de descubrir el generador de progreso que la Nanomedicina significa para la salud como creador de nuevas oportunidades en el diagnóstico y el tratamiento del cáncer. \nNANO WORLD CANCER DAY es un evento que se inició en 2013 y está organizado a nivel europeo por  ETP Nanomedicine (European Technology Platform)\, en el marco del proyecto europeo ENATRANS (Enabling Nanomodicine Translation)\, y de manera local por los diferentes componentes de la plataforma en cada país\, en España\, NanomedSpain. \n 
URL:https://ibecbarcelona.eu/event/nano-world-cancer-day-2017-barcelona-2/
LOCATION:Vall d’Hebron\, Barcelona\, Spain
CATEGORIES:External symposium / conference / congress
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170120T120000
DTEND;TZID=Europe/Madrid:20170120T140000
DTSTAMP:20260405T175911
CREATED:20170116T144347Z
LAST-MODIFIED:20170116T145142Z
UID:27082-1484913600-1484920800@ibecbarcelona.eu
SUMMARY:PhD thesis defence: Pilar Rodríguez
DESCRIPTION:“Mechanics of boundary formation in epithelial monolayers by Eph-ephrin interactions”\nPilar Rodríguez\, Integrative cell and tissue dynamics group\nPilar will be defending her PhD thesis on Friday 20th January at 12:00 at the UB’s Faculty of Medicine (Hospital Clinic)\, room 9\, 3rd floor. \nEverybody is welcome to attend. \n—\nIf you’re an IBEC PhD student and would like to advertise your PhD defence on the IBEC calendar\, please contact vleigh@ibecbarcelona.eu
URL:https://ibecbarcelona.eu/event/27082/
LOCATION:room 9\, 3rd floor\, Faculty of Medicine\, c/ Casanova 143\, Barcelona\, Spain
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170120T120000
DTEND;TZID=Europe/Madrid:20170120T140000
DTSTAMP:20260405T175911
CREATED:20170116T144347Z
LAST-MODIFIED:20170116T144347Z
UID:95974-1484913600-1484920800@ibecbarcelona.eu
SUMMARY:PhD thesis defence: Pilar Rodríguez
DESCRIPTION:“Mechanics of boundary formation in epithelial monolayers by Eph-ephrin interactions”\nPilar Rodríguez\, Integrative cell and tissue dynamics group\nPilar will be defending her PhD thesis on Friday 20th January at 12:00 at the UB’s Faculty of Medicine (Hospital Clinic)\, room 9\, 3rd floor. \nEverybody is welcome to attend. \n—\nIf you’re an IBEC PhD student and would like to advertise your PhD defence on the IBEC calendar\, please contact vleigh@ibecbarcelona.eu
URL:https://ibecbarcelona.eu/event/27082-2/
LOCATION:room 9\, 3rd floor\, Faculty of Medicine\, c/ Casanova 143\, Barcelona\, Spain
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20170116T120000
DTEND;TZID=Europe/Madrid:20170116T130000
DTSTAMP:20260405T175911
CREATED:20170111T111500Z
LAST-MODIFIED:20170111T111500Z
UID:27046-1484568000-1484571600@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Christian A. Nijhuis
DESCRIPTION:Molecular Diodes with Rectification Ratios of Nearly Six Orders of Magnitude\nChristian A. Nijhuis\, Department of Chemistry\, National University of Singapore\nOne of the major goals of molecular electronics is to relate the performance and electronic function of molecular devices to the chemical structure and intermolecular interactions of the organic molecules inside them. Molecular electronic devices are complex physical-organic systems that consist of at least two electrodes\, the organic component\, and two (different) organic/inorganic interfaces. Singling out the contribution of each of these components to the device performance is not straightforward. Besides\, fabrication of molecular junctions is still challenging and defects have to be minimized. \nDuring the talk\, I will discuss our recent progress of molecular diodes based on self-assembled monolayers (SAMs) of ferrocene-alkanethiolates of the form H(CH2)nFc (Fc = ferrocene) sandwiched between two electrodes. I will discuss in detail how we fabricate the junctions (using the well-characterized “EGaIn”-technique) and characterize our junctions and SAMs. We have investigated the various sources of defects in the junctions caused by the impurities in the SAM precursors\,[1] defects in the electrode material\,[2] or subtle changes to the electronic[3] and supramolecular structure of the junctions.[4] We used this accumulated knowledge to develop a well-performing diode that blocks the current in one direction of bias\, but allows it to pass through in the other\, with a difference of a factor of 6.3 x 105.[5\,6] \nWe hope that our findings will help to guide future experiments and to explain why some on paper promising diodes had disappointing performances.[7] \nReferences\n1) Jiang\, L.; Yuan\, L.; Cao\, L.; Nijhuis\, C. A. J. Am. Chem. Soc. 2014\, 136\, 1982.\n2) Yuan\, L.; jiang\, L.; Thompson\, D.; Nijhuis\, C. A. J. Am. Chem. Soc. 2014\, 136\, 6554.\n3) Yuan\, L.; Nerngchamnong\, N.; Cao\, L.; Hamoudi\, H.; Del Barco\, E.; Roemer\, M.; Sriramula\, R.; Thompson\, D.; Nijhuis\, C. A. Nat. Commun. 2015\, 6.\n4) Nerngchanmnong\, N.; Yuan\, L.; Qi\, D. C.; Jiang\, L.; Thompson\, D.; Nijhuis\, C. A. Nat. Nanotechnol. 2013\, 8\, 113.\n5) Yuan\, L.; Breuer\, R.; Jiang\, L.; Schmittel\, M.; Nijhuis\, C. A. Nano Lett. 2015\, 15\, 5506.\n6) Chen\, X.; Roemer\, M.; Yuan\, L.; Wei\, D.; Del Barco\, E.; Thompson\, D.; Nijhuis\, C.A. submitted\n7) Thompson\, D.; Nijhuis\, C. A. Acc. Chem. Res. 2016\, 49\, 2061
URL:https://ibecbarcelona.eu/event/ibec-seminar-christian-a-nijhuis/
CATEGORIES:IBEC Seminar
END:VEVENT
END:VCALENDAR