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X-WR-CALNAME:Institute for Bioengineering of Catalonia
X-ORIGINAL-URL:https://ibecbarcelona.eu
X-WR-CALDESC:Events for Institute for Bioengineering of Catalonia
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20240119T100000
DTEND;TZID=Europe/Madrid:20240119T110000
DTSTAMP:20260404T124022
CREATED:20240104T082933Z
LAST-MODIFIED:20240104T083058Z
UID:113766-1705658400-1705662000@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Al Jord
DESCRIPTION:Mechanisms of Organelle Remodeling for Cellular Function\nAl Jord\, Group leader of Mechanisc of organelle remodeling group\, Centre for Genomic Regulation\, Barcelona \nTo function\, organisms rely on vital organs which\, in turn\, rely on specialized cells. At the subcellular scale\, cell specialization is notably driven by robust mechanisms of organelle remodeling. Thus\, discovering these mechanisms is key for the fundamental understanding of organisms in health and disease\, as well as for improved organ engineering. In this seminar\, I will discuss my research on organelle remodeling in somatic and female germ cells. I will first show how multiciliated cells – critical for nervous\, respiratory and reproductive organs – repurpose conserved mechanisms of cell division to remodel organelles for motile ciliogenesis. I will then talk about how oocytes deploy a biophysical mechanism\, based on cytoplasmic force tuning\, to mechanically remodel nuclear RNA-processing organelles for reproductive success. I will conclude with some future research plans\, blending my past and present interests into an interdisciplinary project that will venture into unexplored grounds of nuclear organelle mechano-regulation in somatic cells to deepen our understanding of organ development and homeostasis. \n\nKey relevant publications : \n  \nAl Jord\, A. et al. Centriole amplification by mother and daughter centrioles differs in multiciliated cells. Nature 516\, 104–107 (2014). \n  \nAl Jord\, A. et al. Calibrated mitotic oscillator drives motile ciliogenesis. Science 358\, 803–806 (2017). \n  \nAl Jord\, A. et al. Cytoplasmic forces functionally reorganize nuclear condensates in oocytes. Nat. Commun. 13:5070\, 1–19 (2022).
URL:https://ibecbarcelona.eu/event/ibec-seminar-al-jord/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20240115T100000
DTEND;TZID=Europe/Madrid:20240115T133000
DTSTAMP:20260404T124022
CREATED:20240108T153848Z
LAST-MODIFIED:20240108T155248Z
UID:113853-1705312800-1705325400@ibecbarcelona.eu
SUMMARY:PhD Thesis Defense: Alis Olea
DESCRIPTION:Dynamics of nanoparticles in 3D tumor models\n\n\n\n\nAuthor: Alis Olea\, Nanoscopy for nanomedicine group\n\n\nReading date: 15/01/2024\nReading time: 10:00 \n\n\nReading place: Sala Eduard Fontserè \nIf you want to join online\, you can connect via Teams here.
URL:https://ibecbarcelona.eu/event/phd-thesis-defense-alis-olea/
LOCATION:Eduard Fontseré – Facultat de Física de la UB
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20240112T100000
DTEND;TZID=Europe/Madrid:20240112T110000
DTSTAMP:20260404T124022
CREATED:20231221T143650Z
LAST-MODIFIED:20240103T092736Z
UID:113540-1705053600-1705057200@ibecbarcelona.eu
SUMMARY:Transversal skills: Tess Marschner
DESCRIPTION:ANIMAL REMINDER\nPosthuman\, queer and animate perspectives on (Techno)Sciences \nI will introduce my previous artistic work and share the current state of my project at Ibec. It would be magnificent if my presentation leads to further thoughts and collaborations that are of interest to my project. \nI will focus on my installation work ANIMAL REMINDER in terms of intertwining artistic and scientific knowledge production. The philosopher Martha C. Nussbaum describes animal reminders as parts or aspects of the human body that evoke a strong aversion or even disgust: Blood\, saliva\, urine\, sweat\, amniotic fluid\, pus\, breast milk\, faeces\, ejaculate. Body surfaces of living beings are perforated several times\, ANIMAL REMINDER emerge from pores and body orifices\, interfaces of skins and mucous membranes at the boundary to air\, water and earth. ANIMAL REMINDER are reminiscent of the process of decomposition\, of slimy animals\, the uncontrollable loss of bodily fluids. They remind us that we ourselves are mortal and animal beings. \nIn case you are heavily interested in my work but unable to attend\, feel free to write me a pm and we can figure out a personal meeting.
URL:https://ibecbarcelona.eu/event/transversal-skills-tess-marschner/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:PhD Discussions Complementary Skills Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231220T163000
DTEND;TZID=Europe/Madrid:20231220T183000
DTSTAMP:20260404T124022
CREATED:20231122T105131Z
LAST-MODIFIED:20231122T110757Z
UID:112763-1703089800-1703097000@ibecbarcelona.eu
SUMMARY:PhD Thesis Defense: Marina Martínez Hernández
DESCRIPTION:Promoting cardiac regeneration by biomimetic microenvironments\n\n\n\n\nAuthor: Marina Martínez Hernández\, Biomaterials for Regenerative Therapies\n\n\nReading date: 20/12/2023\nReading time: 16:30 \n\n\nReading place: School of Mathematics and Statistics of UPC (Sala d’actes\, carrer Pau Gargallo)
URL:https://ibecbarcelona.eu/event/phd-thesis-defense-marina-martinez-hernandez/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231219T200000
DTEND;TZID=Europe/Madrid:20231219T220000
DTSTAMP:20260404T124022
CREATED:20231212T131916Z
LAST-MODIFIED:20231212T131928Z
UID:113275-1703016000-1703023200@ibecbarcelona.eu
SUMMARY:Christmas Party 2023
DESCRIPTION:There’ll be food\, drink\, music and some fun surprises at this most wonderful time of the year!\n\n\nVenue \n\n\n\nFifteen restaurant (PCB) \n\n\nProgramme \n\n\n20:00 – 21:00 · Sale of raffle tickets\n20:00 – 22:00 · Christmas appetizer\n22:00 · Raffle and party\n00:30 · End \n\n\n\nWhen you register\, you’ll have a chance to choose a charity to be a beneficiary of our annual raffle. Tickets will be sold at the beginning of the event(€1 each) to support the chosen charity. \nhttps://events.ibecbarcelona.eu/christmas/ \n 
URL:https://ibecbarcelona.eu/event/christmas-party-2023/
LOCATION:Fifteen Restaurant\, PCB
CATEGORIES:Social / Internal / PhD Committee
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231219T100000
DTEND;TZID=Europe/Madrid:20231219T110000
DTSTAMP:20260404T124022
CREATED:20231212T123816Z
LAST-MODIFIED:20231215T121923Z
UID:113273-1702980000-1702983600@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Prof. Aitor Aguirre
DESCRIPTION:Reverse engineering human heart  development with pluripotent stem cells\nProf. Aitor Aguirre\, Institute for Quantitative Health Science and Engineering (IQ) and the Department of Biomedical Engineering at Michigan State University  \nDuring development\, an exquisitely orchestrated series of biological processes lay down the map for the entirety of our bodies and carry it out to perfection. However\, occasional errors occur (due to mutations\, environmental factors\, and other causes) and lead to congenital defects\, the most common birth defect in humans affecting 1% of all newborns. Certain conditions such as obesity\, diabetes\, infections or drug use can increase this risk much further.\nTo tackle CHDs\, we are reverse engineering human heart development on a dish with the use of pluripotent stem cells\, creating heart organoids or synthetic mini-hearts. By recapitulating  aspects of heart development in vitro\, under fully controlled conditions\, we can dissect gene networks and morphological changes that give rise to specific parts of the heart to understand and prevent CHD\, such as single ventricle defects. Furthermore\, we can also use these mini-hearts as models to study the exposure to environmental conditions and other factors that are very poorly known. \n\nDr. Aguirre obtained his B.S. in Biology and M.S. in Biochemistry and Molecular Biology at the University of the Basque Country and his Ph.D. in Material Science at the Institute for Bioengineering of Catalonia (IBEC). For his postdoctoral training Dr. Aguirre joined The Salk Institute under the supervision of J.C. Izpisua-Belmonte\, where he explored in vivo reprogramming applied to cardiac regeneration\, making significant contributions to non-coding RNA biology in human cardiac development (Cell Stem Cell\, 2014; Circulation\, 2015). Dr. Aguirre became Assistant Professor of Medicine at the University of California\, San Diego in 2017 and joined the Institute for Quantitative Health Science and Engineering (IQ) and the Department of Biomedical Engineering at Michigan State University one year later. He became associate professor in 2023 and is currently the Chief of IQ’s Developmental and Stem Cell Biology Division and the Director of MSU’s Stem Cell Core Facility. Dr. Aguirre has extensive experience in cardiac development\, cardiovascular disease\, tissue engineering and -omic approaches. Dr. Aguirre has received numerous awards and nominations including the Hispanic Center of Excellence award at the University of California\, a career development NHLBI K01 award and frequently serves in grant review panels for the NIH and European Commission\, among others.
URL:https://ibecbarcelona.eu/event/ibec-seminar-prof-aitor-aguirre/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231215T140000
DTEND;TZID=Europe/Madrid:20231215T150000
DTSTAMP:20260404T124022
CREATED:20231211T113708Z
LAST-MODIFIED:20231211T113913Z
UID:113211-1702648800-1702652400@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Pavan Kumar Bosukonda
DESCRIPTION:Smart artificial microcompartments: motility and communication\nPavan Kumar Bosukonda\, Assistant Professor at the Department of Chemistry\, Indian Institute of Technology Roorkee \n  \nNature is a continuous source of inspiration for the design of smart and intelligent materials. In particular\, cells which are the building blocks of life display a complex symphony of various chemical/physical processes which make “life” possible and give it the characteristics which enable life to flourish and sustain. The topology of control systems in place within living cells offer many lessons in design of smart artificial microcompartments or microbots. In this talk\, I will be discussing examples of microcompartments which are capable of smart adaptive motility\, self-assembly and chemical-mediated communication with each other. We use simple buoyancy forces to regulate movement of our microcapsules and use antagonistic control to design relatively complex autonomous behavior by employing stratified chemical environments. The motile microcapsules can turn on/off chemical reactions and carry out logistics of molecular cargo. Also\, I will discuss how we can use the combination of a stimuli responsive hydrogel and stratified environments to design a chemo-mechanical oscillator.  Another focus will be our results on multiphase coacervates and how they formulate a pathway for self-assembly of microdroplets into clusters or tissue-like structures and trigger chemical communication between them. \n\nBrief Bio: Dr. Pavan Kumar Bosukonda is an Assistant Professor at the Department of Chemistry\, Indian Institute of Technology Roorkee. He carried out his doctoral studies at Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR)\, Bangalore\, in the field of porous materials wherein his specific interest was to use supramolecular strategies for pore engineering in mesoporous silica. After completing his Ph.D. in 2015\, he moved to the University of Bristol\, UK\, to work with Prof. Stephen Mann as a Marie-Sklodowska-Curie Postdoctoral Fellow in the field of protocells. His current research interests are focused on developing strategies to fabricate motile microcompartments\, study of multiphase dynamics in liquid-liquid phase separation and designing strategies for regulating chemical communication between microcompartments.
URL:https://ibecbarcelona.eu/event/ibec-seminar-pavan-kumar-bosukonda/
LOCATION:Sala Olivera\, Tower I\, Floor 11
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231215T100000
DTEND;TZID=Europe/Madrid:20231215T110000
DTSTAMP:20260404T124022
CREATED:20231127T122753Z
LAST-MODIFIED:20231204T154540Z
UID:112845-1702634400-1702638000@ibecbarcelona.eu
SUMMARY:PhD Discussions: Zhendong Xie and Júlia Alcàcer
DESCRIPTION:Integrating phenotypic targeting in physiologically-based pharmacokinetics modeling.\nZhendong Xie\, Molecular Bionics group \nSelective drugging\, also known as the “magic bullet\,” is the concept that drugs can target specific molecules\, cells\, or targets while minimising interactions with other parts of the body. Nanoparticles (NPs) with functioned ligands target cells with a certain range of receptors due to the multivalent effect. To develop precision drugs\, it is crucial to understand how NPs are distributed in different organs and interact with different cell types in vivo. Our focus is on investigating the distribution of poly(2-(methacryloyloxy)ethylphosphorylcholine)-poly(2-(diisopropyl-amino)ethyl methacrylate) (PMPC-PDPA) polymersome. We use the PMPC polymersome’s interactions with different receptors to target specific cell groups based on phenotypic association theory (PAT)\, a statistical model based on the description between nanocarriers and cell phenotype (receptor density and glycocalyx). \nWe integrate phenotypic targeting in physiologically-based pharmacokinetics modeling (PBPK) to mimic the distribution of NPs in organs in silico to identify the most selective combination of parameters for precision drugs. The PBPK is built based on the circulation system\, anatomy data\, and cell protein atlas to predict the distribution of NPs among different organs\, considering the advection among various biological fluids\, diffusion of NPs in different organs\, and NPs’ interaction with different cells. A non-Langmiur differential rate equation (NLDRE) is applied to extrapolate the PMPC-cell interaction kinetics based on single-cell level uptake experiments. The association constant/affinity kA/j is derived from the PAT to reveal the selectivity of NPs to different cells. We propose that the difference in kA/j results in a larger distribution and cell targeting discrimination. \nThrough experiments in vivo\, we obtained information about drug distribution among different organs\, the selectivity of NPs to different cells\, and some undetectable parameters such as glycocalyx density. Based on these parameters\, we change the injected dose\, the NP radius\, and the polymerization of the PMPC ligand to simulate the distribution of PMPC in silico and develop a better administration strategy. \n\nExploring host-pathogen interactions: Unraveling the dynamics of Pseudomonas aeruginosa and Burkholderia cenocepacia infection in Galleria mellonella\nJúlia Alcàcer\, Bacterial infections: antimicrobial therapies group \nPseudomonas aeruginosa and Burkholderia cenocepacia are two multidrug-resistant opportunistic pathogens often isolated from the lungs of cystic fibrosis patients. It is known that the presence of more than one species in an infection promotes the appearance of a network of interactions that can lead to an increase in their antimicrobial tolerance or to the evasion of the host immune system. Galleria mellonella has been used as an animal model throughout this study\, as its immune system is comparable to that of mammals\, and it presents practical advantages such as their easy maintenance. With the aim of understanding bacterial and host behaviors after infection\, the survival rate of Galleria mellonella after a P. aeruginosa and B. cenocepacia single and dual-species infection was monitored\, as well as the efficacy of antibiotic treatment to such infections. In order to characterize the infection evolution\, the tissue-specific infection dissemination and hemocyte phagocytosis were evaluated through confocal microscopy.
URL:https://ibecbarcelona.eu/event/phd-discussions-zhendong-xie-and-julia-alcacer/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:PhD Discussions Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231214T103000
DTEND;TZID=Europe/Madrid:20231214T140000
DTSTAMP:20260404T124022
CREATED:20231128T140435Z
LAST-MODIFIED:20231128T140435Z
UID:112919-1702549800-1702562400@ibecbarcelona.eu
SUMMARY:Nanomed Spain: JORNADA SOBRE PROYECTOS DE COLABORACIÓN PÚBLICO-PRIVADA 2023 (Spanish)
DESCRIPTION:NANOMEDSPAIN organizes together with the Leitat technology center a conference on the call for Public-Private Collaboration Projects that will open at the beginning of 2024. \nMª Estefanía Freitas\, Deputy Head of the Scientific-Technical Thematic Programs Branch of the State Research Agency\, Ministry of Science and Innovation\, will present the most important aspects and main novelties of the call. \nThe day will also have the possibility of holding meetings between interested parties and Mª Estefanía Freitas\, and B2B meetings between those attending the day. \nThis event will be in Spanish.
URL:https://ibecbarcelona.eu/event/nanomed-spain-jornada-sobre-proyectos-de-colaboracion-publico-privada-2023-spanish/
LOCATION:Cambra de Comerç\, Av. Diagonal\, 452 – 454\, Barcelona
CATEGORIES:External seminar,Professional and Personal Development
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231201T120000
DTEND;TZID=Europe/Madrid:20231201T130000
DTSTAMP:20260404T124022
CREATED:20231122T092220Z
LAST-MODIFIED:20231122T105201Z
UID:112738-1701432000-1701435600@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Dr. Neil Lin
DESCRIPTION:Epithelial Cell Variability is Governed by Physics Principles and Has Mechanobiology Impacts\nDr. Neil Lin\,  Assistant Professor of Mechanical Engineering and Bioengineering at University of California\, Los Angeles (UCLA). \nBiological systems inherently exhibit variability\, seen in diverse cell shapes\, sizes\, and mechanical properties. Despite its prevalence\, our understanding of the role of phenotypic heterogeneity in cell biology is incomplete. This talk explores how basic physics governs cell-to-cell variability in epithelial monolayers and its impact on biological processes. The first part covers how cell shape heterogeneity influences chromatin organization during crowding. The second part demonstrates that in deformed epithelial layers\, nucleo-cytoskeleton coupling regulates intracellular strain distribution\, influencing cellular mechanoresponse and gene expression. Overall\, cell-cell variability significantly shapes tissue development and remodeling. \n\nDr. Neil Lin is an Assistant Professor of Mechanical Engineering and Bioengineering at University of California\, Los Angeles (UCLA). He obtained his Ph.D. in physics at Cornell University\, studying the microscopic mechanisms that underlie the non-Newtonian suspension flow property. From there\, he went on to do a postdoctoral fellowship at Harvard University\, studying approaches to recreate microenvironment cues for recapitulating kidney functions in vitro. He joined UCLA in 2019\, and his research is to utilize mechanobiology principles to engineer epithelial tissues. His honors include an NIH MIRA\, Prostate Cancer Foundation Young Investigator Award\, and BMES CMBE Rising Star Award.
URL:https://ibecbarcelona.eu/event/ibec-seminar-dr-neil-lin/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231130T150000
DTEND;TZID=Europe/Madrid:20231130T170000
DTSTAMP:20260404T124022
CREATED:20231128T162802Z
LAST-MODIFIED:20231128T162802Z
UID:112941-1701356400-1701363600@ibecbarcelona.eu
SUMMARY:She leads: round table
DESCRIPTION:We are excited to announce an upcoming event that promises to be both insightful and empowering – the “She Leads” Round Table Discussion. This event will bring together distinguished participants from IBEC\, including group leaders\, senior researchers\, and professionals from management\, to share their experiences and insights on leadership\, mentoring\, and the challenges they have faced throughout their careers. \n  \nDate: November 30th\,  \nHour: 15:15 – 17:00 h \nPlace: IBEC; Room Baobab\, Tower I Floor 11 \nChairs: Teresa Sanchis (Head of Strategy) & Ainhoa Ferret (Predoctoral researcher) \nSpeakers:  \n\nElena Martínez Fraiz – Group Leader – Biomimetic Systems for Cell Engineering\nIrene Marco Rius – Junior Group Leader – Molecular Imaging for Precision Medicine\nLorena Ruiz Pérez – Senior researcher – Molecular Bionics\nAnabel-Lise Le Roux – Senior researcher – Cellular and Molecular Mechanobiology\nTeresa Galán Cascales – Microfab and Microscopy Characterization Facilities Coordinator – Core Facilities Unit\n\n  \n  \n 
URL:https://ibecbarcelona.eu/event/she-leads-round-table/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:Professional and Personal Development
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231124T173000
DTEND;TZID=Europe/Madrid:20231124T193000
DTSTAMP:20260404T124022
CREATED:20231026T101820Z
LAST-MODIFIED:20231116T114938Z
UID:111876-1700847000-1700854200@ibecbarcelona.eu
SUMMARY:Cloenda de la 6 edició de bojos i boges per la Bioenginyeria
DESCRIPTION:El dia 24 de novembre celebrem la cloenda de la 6a edició del programa Bojos i boges per la Bioenginyeria on els participants d’enguany presentaran les seves idees i rebran els seus diplomes. \nThis event will be in Catalan. \n  \nDivendres 24 de novembre – 17:30h\nSala Dolors Aleu\, Parc Científic de Barcelona (C. Baldiri Reixac\, 4-8\, 08028 Barcelona) \nPrograma:\n17:15-17:30 – Rebuda dels participants \n17:30-17:45 – Inauguració de la sessió \nPere Roca\, Institut de Bioenyingeria de Catalunya \n17:45- 18:00 – Què significa per a una investigadora participar en el programa? \nAlba Herrero\, investigadora del grup “Molecular Imaging for Precision Medicine”\, IBEC \n18:00-19:00 – Presentació de treballs finals \n19:00-19:15 – Lliurament de diplomes \n19:15 – Agraïments i cloenda \nPere Roca\, Institut de Bioenyingeria de Catalunya (7 minuts) \nLluis Farres\, Director Coneixement i Recerca a la Fundació Catalunya la Pedrera (7 minuts) \n19:30 – Final de la jornada \nRegistre aquí.
URL:https://ibecbarcelona.eu/event/cloenda-de-la-6-edicio-de-bojos-i-boges-per-la-bioenginyeria/
LOCATION:Sala Dolors Aleu\, Parc Científic de Barcelona\, Barcelona\, Spain
CATEGORIES:Outreach / Fair / Festival
ORGANIZER;CN="IBEC":MAILTO:www.ibecbarcelona.eu
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20231121
DTEND;VALUE=DATE:20231124
DTSTAMP:20260404T124022
CREATED:20230912T113348Z
LAST-MODIFIED:20230912T113348Z
UID:110812-1700524800-1700783999@ibecbarcelona.eu
SUMMARY:NanoBio&Med2023
DESCRIPTION:The NanoBio&Med2023 is going to present the most recent international developments in the field of Nanobiotechnology and Nanomedicine and will provide a platform for multidisciplinary communication\, new cooperations and projects to participants from both science and industry. Emerging and future trends of the converging fields of Nanotechnology\, Biotechnology and Medicine will be discussed among industry\, academia\, governmental and non-governmental institutions. NanoBio&Med2023 will be the perfect place to get a complete overview into the state of the art in those fields and also to learn about the research carried out and the latest results. The discussion in recent advances\, difficulties and breakthroughs will be at his higher level.\nAn industrial forum will be organized to promote constructive dialogue between business and public leaders and put specific emphasis on the technologies and applications in the nanoBioMed sector.\n \n  \nMore information here.
URL:https://ibecbarcelona.eu/event/nanobiomed2023/
CATEGORIES:External symposium / conference / congress
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231118T120000
DTEND;TZID=Europe/Madrid:20231118T200000
DTSTAMP:20260404T124022
CREATED:20231026T103045Z
LAST-MODIFIED:20231026T104440Z
UID:111883-1700308800-1700337600@ibecbarcelona.eu
SUMMARY:La Medicina del Futur en Vinyetes﻿
DESCRIPTION:Et preguntes com s’està dissenyant la medicina del futur? \nThis activity will be in Catalan and Spanish. \nDes de nanorobots per combatre cèl·lules canceroses fins a músculs en un xip per a tractar la distròfia muscular. Noves estratègies per a vèncer els superbacteris i fàrmacs que s’activen amb la llum per actuar exclusivament en el lloc de la malaltia. \nTot això t’ho expliquem amb les històries de l’IBBI\, la superheroïna de la bioenginyeria. \nParticipa de la ciència més avantguardista explicada pels seus protagonistes. Vine i emporta’t un còmic signat per ells. \nMés informació a l’enllaç.
URL:https://ibecbarcelona.eu/event/la-medicina-del-futur-en-vinyetes/
LOCATION:Centre Comercial El Triangle Plaza Catalunya 4\, 08002 – Barcelona
CATEGORIES:Outreach / Fair / Festival
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231117T090000
DTEND;TZID=Europe/Madrid:20231117T170000
DTSTAMP:20260404T124022
CREATED:20231026T093406Z
LAST-MODIFIED:20260227T115008Z
UID:111872-1700211600-1700240400@ibecbarcelona.eu
SUMMARY:Plan Complementario de Biotecnología Aplicada a la Salud: el futuro de la medicina personalizada
DESCRIPTION:La jornada “Plan Complementario de Biotecnología Aplicada a la Salud: el futuro de la medicina personalizada” es un evento organizado en el marco del Plan Complementario de Biotecnología aplicada a la Salud en Cataluña. \nDurante el evento se presentarán las principales acciones colaborativas coordinadas desde Cataluña que cuentan con la colaboración de las comunidades autónomas participantes en el Plan. Estos proyectos abarcan desde el desarrollo e implementación de modelos integrados de inteligencia artificial para predecir el riesgo de determinadas enfermedades hasta el desarrollo de nuevos métodos para el cribado de fármacos que ayuden a acelerar el descubrimiento de nuevas dianas terapéuticas\, así como el desarrollo de técnicas avanzadas para la mejora de procesos quirúrgicos y técnicas de realidad virtual y aumentada. \nAsimismo\, se presentarán las diferentes plataformas tecnológicas de apoyo a la I+D financiadas por el Plan Complementario en Cataluña\, y que serán de acceso abierto a toda la comunidad de I+D española. Dos de ellas se podrán visitar al final de la jornada:   Plataforma de Cribado de Fármacos del IRB  y  Escáner de Resonancia Magnética nuclear 3T preclínico (MRI)  del IBEC. \nEl objetivo de la jornada es que sea un lugar de encuentro y networking que ayude a estimular y fortalecer colaboraciones entre los diferentes actores del ecosistema de investigación traslacional en salud en Cataluña y con el resto de las comunidades autónomas participantes en el Plan.  \nRegistro aquí \n\nEl Plan Complementario de Biotecnología Aplicada a la Salud ha sido cofinanciado por el Ministerio de Ciencia\, Innovación y Universidades con fondos de la Unión Europea NextGenerationEU\, el Plan de Recuperación\, Transformación y Resiliencia (PRTR-C17.I1). \n 
URL:https://ibecbarcelona.eu/event/plan-complementario-de-biotecnologia-aplicada-a-la-salud-el-futuro-de-la-medicina-personalizada/
LOCATION:Auditori Antoni Caparrós\, PCB\, Tower D\, c/Baldiri Reixac 4-8\, Barcelona\, Spain
CATEGORIES:IBEC Symposium / Conference / Congress / Workshop
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231115T120000
DTEND;TZID=Europe/Madrid:20231115T130000
DTSTAMP:20260404T124022
CREATED:20231108T114522Z
LAST-MODIFIED:20231108T120448Z
UID:112510-1700049600-1700053200@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Martí Duocastella
DESCRIPTION:Toward the next generation of 3D optical microscopes: faster\, deeper\, and label-free\nMartí Duocastella\, Departament de Fisica Aplicada\, Universitat de Barcelona \nThree-dimensional (3D) optical microscopy is the tool of choice for characterizing the structure and dynamics of biological systems at sub-cellular resolution. However\, most microscope architectures are tailored to capture two-dimensional (2D) information from moderately thin samples labeled with fluorophores. Due to constraints posed by light scattering and the requirement for mechanical focus translation\, existing systems provide shallow penetration depth and low volumetric imaging speed\, thus falling short of unraveling biological complexity inside medium-sized organisms or even organoids. In this talk\, I will discuss our efforts to overcome these issues and achieve sub-millisecond imaging at potentially millimeter depths and without labels. Our strategy consists of focusing\, modulating\, and guiding light by exploiting the acousto-optic effect\, that is\, ultrasound-induced refractive index gradients. The unique interaction between ultrasound and light enables rapid 3D light control\, making it suitable for the development of inertia-free light sheet microscopes that lack mechanically moving parts and offer imaging rates of tens of volumes per second. It also facilitates illumination encoding in single-pixel cameras\, enabling scanless 2D imaging at 5 kHz. Interestingly\, applying ultrasonic waves in a scattering medium acts as an instantaneous waveguide embedded in the medium\, helping to redirect light toward a 7-fold deeper focus. I will discuss the advantages and pitfalls of these acousto-optic technologies and illustrate them with applications\, including imaging of spheroids and flowing samples. \n\nMartí Duocastella is a Serra Hunter full professor in the Department of Applied Physics at Universitat de Barcelona (UB) and leader of the Dynamic Optical Systems Lab. He completed his PhD in Physics at UB in 2010 and then moved to Princeton University as a postdoctoral research associate\, where he also became the vice-president of Research and Development of the startup company TAG Optics. In 2014 he joined Istituto Italiano di Tecnologia as a researcher (group leader)\, until returning to Barcelona as a faculty member in 2019. His research focuses on novel optical methods for three-dimensional (3D) light engineering\, with applications in materials science\, sensing\, and biology. He is an ERC Consolidator Grant awardee. \nIn 2012\, he was appointed a Ramon Y Cajal (RyC) researcher\, but after two years as a RyC\, he decided to move back to Switzerland where in 2015 was awarded an ERC starting grant to study and control self-assembly processes of metal-organic based crystalline materials. In 2019\, he was appointed as an ICREA professor and since August 2020 his group is located at the University of Barcelona (UB)
URL:https://ibecbarcelona.eu/event/ibec-seminar-marti-duocastella/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231110T100000
DTEND;TZID=Europe/Madrid:20231110T120000
DTSTAMP:20260404T124022
CREATED:20231004T105307Z
LAST-MODIFIED:20231004T105307Z
UID:111448-1699610400-1699617600@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Josep Puigmartí-Luis
DESCRIPTION:What can microfluidic technologies offer during self-assembly processes?\nJosep Puigmartí-Luis\, Departament de Ciència dels Materials i Química Física\, Institut de Química Teòrica i Computacional (invited by César Rodriguez-Emmenegger) \nSelf-assembly has long being used to control covalent and non-covalent interactions where molecular design has been the major driving force to achieve a desired outcome. Like in nature\, a full control over self-assembly processes could lead to rationalized structure-property correlations\, a long-time sought in chemistry\, physics and materials science. However\, the pathways followed and the mechanisms underlying the formation of supramolecular aggregates are still a major challenge for the scientific community. Accordingly\, the elucidation of nucleation and growth mechanisms will be highly required to push supramolecular chemistry to the next level\, where access to nature inspired functions will be accomplished. In this contribution\, I will present how reaction-diffusion (RD) conditions established within microfluidic devices can be used to uncover pathway complexity as well as to trigger pathway selection. Specifically\, I will show that microfluidic RD conditions provide an unprecedented kinetic control over self-assembly processes; for example\, enabling the isolation of well-defined kinetically trapped states as well as unprecedented metastable intermediates. This research provides a new tool to study and understand supramolecular chemistry\, and opens up new avenues for the engineering of advanced functional assemblies and systems. \n\nProf. Dr. Josep Puigmartí-Luis is a chemist who completed a master in Chemistry and Food Engineering at “Institut Químico de Serrià (IQS)” (2003) and did a PhD in materials science at Institut de Ciència de Materials de Barcelona (ICMAB). His work in supramolecular and flow chemistry\, has been awarded with “Premi Antoni de Martí i Franquès de Ciències Químiques”\, award from the Institut d’Estudis Catalans (2009)\, St. Jordi award from the Institut d’Estudis Catalans and the Societat Catalana de Química (2006) and an ETH fellowship in 2008. \nIn 2012\, he was appointed a Ramon Y Cajal (RyC) researcher\, but after two years as a RyC\, he decided to move back to Switzerland where in 2015 was awarded an ERC starting grant to study and control self-assembly processes of metal-organic based crystalline materials. In 2019\, he was appointed as an ICREA professor and since August 2020 his group is located at the University of Barcelona (UB).
URL:https://ibecbarcelona.eu/event/ibec-seminar-josep-puigmarti-luis/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231108T100000
DTEND;TZID=Europe/Madrid:20231108T170000
DTSTAMP:20260404T124022
CREATED:20231106T110750Z
LAST-MODIFIED:20231106T110750Z
UID:111999-1699437600-1699462800@ibecbarcelona.eu
SUMMARY:PhD Thesis Defense: Maria Gallo
DESCRIPTION:Human Pluripotent stem cells: towards the definition of the new engineering approaches to target heart and kidney disease\n\n\n\n\nAuthor: Maria Gallo\, Pluripotency for organ regeneration group\n\n\nReading date: 8/11/2023\nReading time: 10:00 \n\n\nReading place: Aula Magna of Hospital Clinic
URL:https://ibecbarcelona.eu/event/phd-thesis-defense-maria-gallo/
LOCATION:Aula Marga\, Hospital Clinic
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231027T110000
DTEND;TZID=Europe/Madrid:20231027T170000
DTSTAMP:20260404T124022
CREATED:20231024T143039Z
LAST-MODIFIED:20231024T145618Z
UID:111800-1698404400-1698426000@ibecbarcelona.eu
SUMMARY:PhD Thesis Defense: Karen Wells Cembrano
DESCRIPTION:Development of 3D in vitro platforms for the study of muscle function and axonal growth and regeneration\n\n\n\n\nAuthor: Karen Wells Cembrano\, Molecular and cellular neurobiotechnology group\n\n\nReading date: 27/10/2023\nReading time: 11:00 \n\n\nReading place: Aula de Graus\, Biology Faculty\, UB \n\nTeams Link here.
URL:https://ibecbarcelona.eu/event/phd-thesis-defense-karen-wells-cembrano/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231020T100000
DTEND;TZID=Europe/Madrid:20231020T113000
DTSTAMP:20260404T124022
CREATED:20231005T130733Z
LAST-MODIFIED:20231010T145141Z
UID:111469-1697796000-1697801400@ibecbarcelona.eu
SUMMARY:PhD Discussions: Thomas Wilson and Judith Fuentes
DESCRIPTION:Multiscale buckling of epithelial shells\nThomas Wilson\, Integrative Cell and Tissue Dynamics group \nNumerous natural and engineered structures are shaped as thin curved shells. When subjected to excessive compressive loading\, these shells undergo buckling instabilities that result in wrinkling patterns with complex dynamics. Epithelial tissues such as those enclosing embryos or lining glandular organs are a class of thin shells that displays three distinctive mechanical features: they are viscoelastic over the time scales of physiological loading\, they carry an active surface tension\, and their stress-bearing elements are distributed across scales. The conditions under which these material properties enable buckling\, and the subsequent structural changes are not understood. Here we establish the buckling dynamics of epithelial shells of controlled geometry over several orders of magnitude in time and space. We developed an experimental system that allows us to sculpt epithelial shells and subject them to controlled pressure differentials. We show that\, under rapid pressure reductions relative to a characteristic viscoelastic time of the system\, the tissue develops buckling patterns with different degrees of symmetry that depend on its size and shape. By contrast\, slow deflations allow the tissues to accommodate large strain variations without buckling. Strikingly\, we find that epithelial buckling is a multiscale phenomenon involving supracellular folds but also subcellular wrinkles in the actin cortex. Additionally\, we can harness the active viscoelastic behaviour of the cell cortex to pattern epithelial folds by rationally directed buckling. Our study shows that epithelial tissues can be understood as hierarchical materials with mechanical instabilities that can be harnessed to engineer morphogenetic events. \n\nEvaluation of self-healing properties in skeletal muscle-based bioactuators\nJudith Fuentes\, Smart Nano-Bio-Devices group \nThree dimensional bioprinting has opened new possibilities for the bioengineering of skeletal muscle models with organization and functionality similar to native tissues. This is key to understand the physiological conditions of skeletal muscle to integrate some of their unique properties\, such as self-healing\, adaptability\, and response to external stimuli\, in biohybrid systems. However\, the inherent self-healing capability of skeletal muscle has not been fully exploited in these advanced biohybrid platforms. In vivo\, skeletal muscle tissue may be repaired via the regenerative function of satellite cells (SC). However\, in in vitro conditions\, these cells are difficult to expand without altering their self-healing potential. Myogenic reserve cells (RC) offer an alternative potentially useful source to implement advanced regenerative capabilities in biohybrid systems. RC present similar properties to SC and arise during in vitro myoblast differentiation when a subpopulation escape from terminal differentiation. This work presents a 3D-bioprinted skeletal muscle bioactuator which self-healing properties have been evaluated after generating physical damage to the tissue\, either by creating cuts or crush injuries. Further studying over the underlying biological events related to muscle repair will be key to moving forward with the design of muscle-based bioactuators with on-demand assisted self-healing properties.
URL:https://ibecbarcelona.eu/event/phd-discussions-thomas-wilson-and-judith-fuentes/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:PhD Discussions Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231011T110000
DTEND;TZID=Europe/Madrid:20231011T130000
DTSTAMP:20260404T124022
CREATED:20231004T102504Z
LAST-MODIFIED:20231004T102504Z
UID:111446-1697022000-1697029200@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Jaap den Toonder
DESCRIPTION:Microfluidic technology enabling biomedical applications\nJaap den Toonder\, Microsystems Research Section\, Department of Mechanical Engineering\, and Institute for Complex Molecular Systems\, Eindhoven University of Technology.  \nCurrently\, visiting professor at IBEC\, Barcelona \nMicrofluidics is the science and technology of manipulating and analyzing fluid flow at small scales\, typically from millimeters down to micrometers. At these scales\, fluid flow is almost always laminar which enables excellent control over the flow. Microfluidic devices can be made using a range of microfabrication approaches and materials\, and these enable to integrate tailored electronic or mechanical functions. These unique properties of microfluidic technologies\, and the ongoing further development of the technology\, enable a range of new biomedical applications\, including diagnostic and monitoring devices\, medical implants\, and organ-on-chip. \nIn this lecture\, I will present recent developments within three research lines of our lab. (1) Bio-inspired microfluidics: A novel microfluidic flow generation concept inspired by nature\, which is based on magnetic nano- and micro-actuators we call “artificial cilia”; integrated in microfluidic devices\, these can be used to induce flow\, to manipulate particles\, and as actuators in cellular mechano-transduction research. (2) Microfluidic devices for health: Examples of microfluidic devices for health applications\, specifically a sweat sensing device for non-invasive semi-continuous monitoring of hospitalized patients\, and a smart eye implant to control eye pressure in glaucoma patients after surgery. (3) Organ-on-chip: A game-changing technology in which human cells are cultured in microfluidic chips simulating and predicting the response of healthy and diseased human tissues. I will focus on cancer-on-chip approaches to understand initial stages of cancer metastasis\, and on our lumen-based organ-on-chip models that are enabled by a 3D sugar printing technique we developed.
URL:https://ibecbarcelona.eu/event/ibec-seminar-jaap-den-toonder/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231010T143000
DTEND;TZID=Europe/Madrid:20231010T163000
DTSTAMP:20260404T124022
CREATED:20231004T123727Z
LAST-MODIFIED:20231004T124040Z
UID:111456-1696948200-1696955400@ibecbarcelona.eu
SUMMARY:Workshop “Bioaction: The new tissue engineering approaches in bone infections"
DESCRIPTION:Workshop held in the framework of the EIC Pathfinder project BIOACTION “Bacteria biofilm as bio-factory for tissue regeneration” (Project Number 101098972). \nBIOACTION aims at developing a new methodology in implant technology based on functionalized bio-hydrogels that will convert the negative occurrence of biofilm-associated infections\, the primary cause of implant infections and failure\, into a positive resource. The main goal of BIOACTION is to transform implant-associated bacteria for the programmable production of specific proteins for in vivo cell recruitment and tissue regeneration\, exploiting gene sequences loaded on engineered liposomes and phages\, bound to hydrogel scaffolds. BIOACTION will develop new biomimetic substrates that can transform biofilm into extracellular matrix for the regeneration of target tissues. It will establish a high versatile technology to be used as injectable materials and implant coatings for periodontal and peri-implant infection treatments. The proposed approach will be validated in two clinically relevant animal models: dental implant and permanent transcutaneous bone. \nBIOACTION\, would radically advance the future of infection treatment by revolutionizing the classical approaches leading to the improvement of state of care\, health outcomes and to achieve huge socio-economic benefits. The project is strongly interdisciplinary in nature involving expertise biomaterials\, synthetic biology\, phage and liposome technology\, medicine. \nAs a results\, this innovative approach will bring the research and knowledge far beyond the current state-of-the-art and will lead\, through the planned validation\, as proof-of-concept of new materials and technique with a broader application in regenerative medicine. \nIn this workshop\, participants from all the institutions involved in the project will explain their research and activities. \n  \nChairs: Elisabeth Engel\, Luigi Ambrosio \n14:30 – Claudia Siverini and Marco Chittò (AO Foundation)\, “Bone infections and treatments” \n14:45 – Dorien Van Hede (Université de Liege)\, “Dental infections and treatments” \n15:00 – Diego Cotella (Università degli Studi del Piemonte Orientale)\, “Phages to control biofilms” \n15:15 – Dr. Cecilia Bombelli (Consiglio Nazionale delle Ricerche – Instituto per i Sistemi biologici)\, “Liposomes in gene therapy” \n15:30 – Ramūnas Valiokas (Ferentis)\, “Crosslinked peptide hydrogels for tissue engineering and modeling” \n15:45 – Giovanna Gomez d’Ayala (Consiglio Nazionale delle Ricerche – Instituto per i Polimeri\, Compositi e Biomateriali)\, “Hydrogels for tissue regeneration” \n16:00 – Oscar Castaño (IBEC)\, “Advanced characterization methodology” \n16:15 – Roberta Marzella (Consiglio Nazionale delle Ricerche – IPCB) and Michela Candotti (IN Society) – “Tips on Management and Dissemination of European Projects” \n16:30 Discussion and conclusions
URL:https://ibecbarcelona.eu/event/workshop-bioaction-the-new-tissue-engineering-approaches-in-bone-infections/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:IBEC Symposium / Conference / Congress / Workshop
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231003T090000
DTEND;TZID=Europe/Madrid:20231003T183000
DTSTAMP:20260404T124022
CREATED:20230619T141528Z
LAST-MODIFIED:20230619T141550Z
UID:108734-1696323600-1696357800@ibecbarcelona.eu
SUMMARY:16th IBEC SYMPOSIUM
DESCRIPTION:BIOENGINEERING FOR FUTURE AND PRECISION MEDICINE\n\n\n\n\nOctober 3rd · Auditori Axa\, Barcelona\nThe 16th IBEC annual Symposium brings together high-profile international experts for an open forum for interdisciplinary discussions and networking. This year the symposium is dedicated to Bioengineering for Future and Precision Medicine\, one of IBEC’s three major application areas. \nScientific community is invited to participate. Attendees from IBEC and abroad are welcome to present their research or projects in poster format. Moreover\, some of these contributions will be selected by the scientific committee for an oral flash presentation. \nRegistration here.
URL:https://ibecbarcelona.eu/event/16th-ibec-symposium/
LOCATION:AXA Auditorium\, L'illa Diagonal\, Av. Diagonal 547 \, Barcelona\, 08029
CATEGORIES:IBEC Symposium / Conference / Congress / Workshop
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20231002T120000
DTEND;TZID=Europe/Madrid:20231002T130000
DTSTAMP:20260404T124022
CREATED:20230912T132001Z
LAST-MODIFIED:20230912T132001Z
UID:110817-1696248000-1696251600@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Simone Reber
DESCRIPTION:Conserved nucleocytoplasmic density homeostasis drives cellular organization across eukaryotes\nSimone Reber\, Max Planck Institut for Infection Biology\, Berlin (invited by Pere Roca-Cusachs) \nThe packing and confinement of macromolecules in the cytoplasm and nucleoplasm has profound implications for cellular biochemistry. How intracellular density distributions vary and affect cellular physiology remains largely unknown. We show that the nucleus is less dense than the cytoplasm and that living systems establish and maintain a constant density ratio between these compartments. Using label-free biophotonics and theory\, we show that nuclear density is set by a pressure balance across the nuclear envelope in vitro\, in vivo and during early development. Nuclear transport establishes a specific nuclear proteome that exerts a colloid osmotic pressure\, which\, assisted by entropic chromatin pressure\, draws water into the nucleus. Using C. elegans\, we show that while nuclear-to-cytoplasmic (N/C) volume ratios change during early development\, the N/C density ratio is robustly maintained. We propose that the maintenance of a constant N/C density ratio is the biophysical driver of one of the oldest tenets of cell biology: the N/C volume ratio. In summary\, this study reveals a previously unidentified homeostatic coupling of macromolecular densities that drives cellular organization.
URL:https://ibecbarcelona.eu/event/ibec-seminar-simone-reber/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20230929T100000
DTEND;TZID=Europe/Madrid:20230929T113000
DTSTAMP:20260404T124022
CREATED:20230912T131744Z
LAST-MODIFIED:20230912T131744Z
UID:110815-1695981600-1695987000@ibecbarcelona.eu
SUMMARY:IBEC Seminar: New technologies for accelerating drug discovery and preclinical testing
DESCRIPTION:New technologies for accelerating drug discovery and preclinical testing\nMaria Majellaro\, Chief Scientific Officer of Celtarys. \nAbi J Vazquez. Co-founder and COO of DIVERSA Technologies SL.\nBruno K Rodiño-Janeiro\, Chief Scientific Officer of BFlow. \n  \nCeltarys\, DIVERSA and BFlow belong to the Galician biotechnology ecosystem and are dedicated to provide cutting-edge technologies applied in different and complementary phases of preclinical drug screening\, accelerating the drug development process and reducing the time to market of new therapies. \nThe three companies emerge from technologies developed at public research centers and transferred to the market after participation in validation programs. The speakers will explain their experiences in the process of going from an idea in the laboratory to the final technology transfer as spin-off companies. \nCeltarys is a spin-off of the University of Santiago de Compostela\, focused on the development of innovative fluorescent tools to improve the efficiency of the drug discovery process. In addition to its fluorescent ligand portfolio\, Celtarys specializes in customized fluorescent ligands for target-based drug discovery\, utilizing its proprietary conjugation technology. This unique approach allows to quickly design and develop libraries of different tailor-made fluorescent ligands with their own linkers covering wide chemical architectures for any target of interest. \nDIVERSA is a spin-off from the Santiago de Compostela Health Research Institute (IDIS) and the Galician Health Service (SERGAS)\, devoted to drive the translation of new therapeutic molecules to the clinic through the application of patented safe-by-design lipid nanoemulsions that can efficiently improve the delivery of drugs and biomolecules (RNAs\, proteins and peptides ) to their target\, and thus efficacy. DIVERSA commercialize ready-to-use reagents\, and also provides customized services for the development of tailored and unique formulations that can accomplish all requirements for a specific molecule\, indication\, and route of administration. We also conduct comprehensive R&D activities to advance our own nanomedicines towards the clinic\, answering to current unmet clinical needs. \n  \nBFlow is a spin-off from the University of Santiago de Compostela (USC) and the Health Research Institute of Santiago de Compostela (IDIS)\, which offers advanced Organ-on-a-chip models to improve the physiological relevance of cell cultures. BFlow products are designed to cover the urgent need to improve the data in both research laboratories and the pharmaceutical industry. Regarding the latter\, Organ-on-a-chip models will have a relevant role reducing the cost\, time and use of experimental animal models in the preclinical drug screening process\, accelerating the discovery of new drugs. \n  \nThe seminar will consist of 15 minute talks from each company with 15 minutes of questions and answers.
URL:https://ibecbarcelona.eu/event/ibec-seminar-new-technologies-for-accelerating-drug-discovery-and-preclinical-testing/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20230927T120000
DTEND;TZID=Europe/Madrid:20230927T130000
DTSTAMP:20260404T124022
CREATED:20230803T110925Z
LAST-MODIFIED:20230803T110925Z
UID:110580-1695816000-1695819600@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Mariano Vázquez
DESCRIPTION:Supercomputer-based virtual humans: the future of medicine NOW\nMariano Vázquez\, ELEM Biotech & Barcelona Supercomputing Center \nIn this talk we are going to address the potential of supercomputer-based virtual humans for the biomedical realm. Virtual Humans are computational “avatars” of a patient\, which combines data with a mathematical model which are used to predict (as opposed to measure with experiments) some quantities of interest\, under a context of use and used to support medical decisions. We will show examples of Populations of Virtual Humans used as cohorts for in-silico clinical trials to optimize drug or devise-based therapies. \nOur examples are mostly of the cardiovascular and respiratory domains.
URL:https://ibecbarcelona.eu/event/ibec-seminar-mariano-vazquez/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20230921T080000
DTEND;TZID=Europe/Madrid:20230921T170000
DTSTAMP:20260404T124022
CREATED:20230907T152119Z
LAST-MODIFIED:20230907T152119Z
UID:110774-1695283200-1695315600@ibecbarcelona.eu
SUMMARY:The Future Now: Emerging Leaders in Biomedicine
DESCRIPTION:We are delighted to announce the first edition of the symposium “The Future Now: Emerging Leaders in Biomedicine“. This event is specifically tailored for advanced postdoctoral researchers and junior Group Leaders who are at the forefront of the vibrant biomedical community of the Barcelona area. Join us at the Josep Carreras Leukaemia Research Institute (IJC) on September 21\, 2023. This Symposium is co-organized by the Josep Carreras Leukaemia Research Institute (IJC)\, the Vall d’Hebrón Institute of Oncology (VHIO)\, the Institute for Bioengineering of Catalonia (IBEC)\,the Institute of Molecular Biology of Barcelona (IBMB)\, the Centre for Genomic Regulation (CRG) and the University Pompeu Fabra\, Department of Medicine and Life Science. \n\nThis symposium will be a unique opportunity for emerging leaders in biomedicine of the region to network\, showcase their cutting-edge research\, and foster collaborations. By participating in this event\, early-career researchers will gain visibility\, build valuable connections\, and contribute to strengthening the local scientific ecosystem. \n\nThe program features a rich scientific agenda encompassing diverse disciplines within biomedicine\, with oral presentations from distinguished young researchers covering basic and translational research\, as well as cutting edge technologies. We will hold an engaging round table discussion focused on the relevant challenges faced by researchers at different stages of becoming independent investigators. Please find the program of the Symposium here. \nThe Emerging Leaders Symposium receives the support of Miltenyi Biotec\, Macrogen\, BGI Genomics\, Bonsai Lab & Labclinics. \n\nREGISTRATION:\n\nWe extend a warm invitation to all postdoctoral researchers and junior Group Leaders in the Barcelona area to join us at the “Emerging Leaders in Biomedicine” symposium. \n\n\nAll participants of the event need to register via the following link: https://forms.office.com/e/LfGzP4tMJT\nRegistration is free.\nDeadline for registration is September 8\, 2023.\n\n\nBy coming together\, we can shape the future of biomedicine\, establish enduring connections\, and contribute to the advancement of science in our local community and beyond. \n\nEMERGING LEADERS BOOK\n\nAttendees will have the opportunity to present their research interests through virtual short presentations in the “Emerging Leaders Book”\, fostering in-depth discussions and providing constructive feedback during the networking session and beyond. It’s an excellent opportunity for participants to refine their research ideas and expand their scientific horizons. \n\nAll participants wishing to appear in the “Emerging Leaders Book” must send their information via the following link before September 8\, 2023: https://forms.office.com/e/pWPrj1rhK6
URL:https://ibecbarcelona.eu/event/the-future-now-emerging-leaders-in-biomedicine/
LOCATION:Josep Carreras Leukaemia Research Institute
CATEGORIES:External symposium / conference / congress
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20230915T100000
DTEND;TZID=Europe/Madrid:20230915T113000
DTSTAMP:20260404T124022
CREATED:20230710T085202Z
LAST-MODIFIED:20230710T085202Z
UID:109584-1694772000-1694777400@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Dr. Andy Tay
DESCRIPTION:Biomaterials for cancer study and accelerate wound healing\nDr. Andy Tay \, Assistant Professor\, Presidential Young Professor\, Department of Biomedical Engineering \nMagnetic hydrogels are materials containing magnetic microparticles which help transduce magnetic fields into mechanical forces. In the presence of a static magnet\, the stiffness of magnetic hydrogels can be altered to investigate the reversible effects of matrix softening and stiffening on cellular behaviours. Here\, I will describe how we exploit this unique feature of our material for cancer study. \nThe World Health Organization estimates that 10% of the world’s population suffers from diabetes\, and diabetic patients has a 15-25% lifetime risk of getting diabetic foot ulcers. Every 20s\, there is a lower extremity amputation worldwide. In the second half of my talk\, I will describe the use of magnetic hydrogel for mechanical stimulation of cells to synergistically accelerate diabetic wound healing. \n\nAndy Tay graduated in 2014 from NUS with a First-Class Honours in Biomedical Engineering. He later headed to the University of California\, Los Angeles for his PhD studies and graduated in 2017 as the recipient of the Harry M Showman Commencement Award. Andy next received his postdoctoral training at Stanford University before heading to Imperial College London as an 1851 Royal Commission Brunel Research Fellow. He is currently a Presidential Young Professor in NUS. \nAndy is a recipient of international awards including the Interstellar Initiative Early-Career Faculty Award\, Christopher Hewitt Outstanding Young Investigator Award\, Terasaki Young Innovator Award. He is listed as a 2019 Forbes 30 Under 30 (US/Canada\, Science)\, 2020 World Economic Forum Young Scientist\, 2020 The Straits Times ‘30 and Under’ Young Singaporeans to Watch and 2022 Top 2% Scientist in the World by Stanford University. \n 
URL:https://ibecbarcelona.eu/event/ibec-seminar-dr-andy-tay/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:IBEC Seminar
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DTSTART;TZID=Europe/Madrid:20230905T100000
DTEND;TZID=Europe/Madrid:20230905T120000
DTSTAMP:20260404T124022
CREATED:20230724T080449Z
LAST-MODIFIED:20230724T080449Z
UID:110271-1693908000-1693915200@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Virgil Percec
DESCRIPTION:Reprogramming the Factory of Life to Target the Delivery of mRNA via Helical Chirality\nVirgil Percec\, Roy & Diana Vagelos Laboratories\, Department of Chemistry\, University of Pennsylvania\, Philadelphia \nHomochiral helical self-organizations are known at the macroscopic level in nature\, art\, architecture and science for thousands of years [1a\,b]. However\, molecular helicity was discovered in proteins and DNA [2] only in the early 1950th and in molecular\, macromolecular and supramolecular complex nanosystems emerged soon after [1c\,d\,e\,f]. Our ability to program functions at the supramolecular level based on helical chirality is less advanced than the same process at the macroscopic level during Archimedes and Leonardo da Vinci times. The principles “discover-elucidate mechanism-predict programmed primary structure” elaborated in our laboratory and aided by synthetic methodologies developed also in our laboratory for accelerated modular-orthogonal synthesis of programmed structures such us Ni-catalyzed cross-coupling\, mixed-ligand\, thio-bromo click\, SET-organic and polymerizarion reactions\, self-accelerated and self-interrupted synthesis including selected examples of homochiral helical self-organizations and functions together with the molecular factory of life will be briefly explained. The origins of helical homochirality is equivalent to the origins of life although the origins and the rational of biological membranes homochirality continues to be debated [3]. Inspiration from amphiphilic Janus dendrimers [4a] and Janus glycodendrimers [4b] discovered in our laboratory allowed to transit from the commercial viral and four-component lipid nanoparticle synthetic vectors for delivery of mRNA to the one-component ionizable multifunctional sequence-defined amphiphilic Janus dendrimers (IAJDs) delivery vector [5]. The current status of the molecular design principles providing the least expensive and the simplest access to targeted delivery of mRNA with programmed IAJDs will be discussed in great details. Targeted delivery of mRNA to all organs is expected to change the field of nanomedicine at the most fundamental level by providing unprecedented avenues to new vaccines and therapeutics. \nReferences \n\n(a) Percec\, V.; Xiao\, Q. Bull. Chem. Soc. Jpn. 2021\, 94\, 900-928. (b) Percec\, V.; Adamson\, J.; Gianti\, E. Supramolecular Nanotechnology\, Wiley-VCH\, 2023\, Azzaroni\, O.; Conda-Sheridan\, M. Eds. Vol.1\, p. 1-123. (c) Percec\, V. Lab. Science 1997\, 278\, 449-452. (d) Nature 1998\, 391\,161-164. (e) Nature 2002\, 419\, 384-387. (f) Nature 2004\, 430\, 764-768.\n(a) Pauling\, L.; Corey\, J. Am. Chem. Soc. 1950\, 72\, 5349-5349; (b) Watson\, J. D.; Crick\, F.H.C. Nature 1953\, 171\, 737-738; (c) Percec\, V.; Xiao\, Q. CHEM 2021\, 7\, 529-536; (d) Percec\, V. CHEM 2023\, August issue.\nPercec\, V. Lab. J. Am. Chem. Soc. 2023\, 145\, 4311-4323.\n(a) Percec\, V. Lab. Science\, 2010\, 328\, 1009-1014; (b) Percec\, V. Lab. J. Am. Chem. Soc. 2013\, 135\, 9055-9077.\n(a) Percec\, V. and Weissman D. Labs. J. Am. Chem. Soc. 2021\, 143\, 12315-12325; (b) J. Am. Chem. Soc. 2021\, 143\, 18803-12325; (c) J. Am. Chem. Soc. 2022\, 144\, 4746-4753; (d) Pharmaceutics 2023\, 15\, 1572; (e) J. Am. Chem. Soc. Submitted.\n\n\nVirgil Percec was born and educated in Romania (BS in Organic and Macromolecular Chemistry at the Polytechnic University in Iasi\, PhD in 1976 with C. I. Simionescu. In 1981 he defected his native country and after short postdoctoral stays at the University of Freiburg in Germany (July 1981 with H. -J. Cantow) and University of Akron\, US (August 1981 to March 1982 with J. P. Kennedy) he joined the Department of Macromolecular Science of Case Western Reserve University in Cleveland\, US in March 1982 as an Assistant Professor. He was promoted to Associate Professor in 1984 and to Professor in 1986. In 1993 he was awarded the Leonard Case Jr. Chair at Case Western Reserve University and in 1999 he was invited and moved to the University of Pennsylvania in Philadelphia as P. Roy Vagelos Chair and Professor of Chemistry. He has been repeatedly a Visiting Professor at the Universities of Freiburg\, Ulm and at the Max Planck Institute for Polymer Research in Mainz (all in Germany) and at the Royal Institute of Technology in Stockholm. His research interest is at the interface between organic\, supramolecular\, macromolecular chemistries\, liquid crystals\, nanoscience and biology where he contributed over 820 refereed publications\, 80 patents\, edited 20 books and presented over 1300 endowed\, invited and plenary lectures. He educated over 3509 students and postdocs over 70 of them being in university professors all over the world.
URL:https://ibecbarcelona.eu/event/ibec-seminar-virgil-percec/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:IBEC Seminar
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20230726T150000
DTEND;TZID=Europe/Madrid:20230726T170000
DTSTAMP:20260404T124022
CREATED:20230712T082101Z
LAST-MODIFIED:20230712T082101Z
UID:109742-1690383600-1690390800@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Matthias Schulze
DESCRIPTION:Highlights of 20 years DNP with Merck as partner\nMatthias Schulze\, Merck \nIntroduction of Merck’s capabilities to supply specifically labeled tracers in different grades.\nDescribing the milestones of DNP towards establishing that method as a powerful tool in cancer diagnostics. Outlining the challenges and the scope on projects utilizing 13 C labeled reagents. \n\nMatthias Schulze studied chemistry at the TU Berlin and gained his PhD in 1991 for research in natural product synthesis. Subsequent stays at various sites abroad (Norman\, Oklahoma and Columbus\, Ohio) extended his expertise in analytical and synthetical techniques. Later\, he worked as a group leader at the University Bonn on mechanistic questions in metal-organic chemistry and new ways to access cyclic natural products. He has 20 years of experience in stable isotopes and its applications in a corporate environment. His current role is that of a technology manager for stable isotopes in EMEA. Ever since he worked with numerous researchers to support them in a broad range of fields\, focusing on biochemical and medicinal topics \n 
URL:https://ibecbarcelona.eu/event/ibec-seminar-matthias-schulze/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:IBEC Seminar
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