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DTSTART;TZID=Europe/Madrid:20200626T100000
DTEND;TZID=Europe/Madrid:20200626T120000
DTSTAMP:20260403T211323
CREATED:20200605T081203Z
LAST-MODIFIED:20200618T100739Z
UID:74893-1593165600-1593172800@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Pere Roca-Cusachs
DESCRIPTION:Sensing the matrix: transducing mechanical signals from integrins to the nucleus\n \nPere Roca-Cusachs \, IBEC \nCell proliferation and differentiation\, as well as key processes in development\, tumorigenesis\, and wound healing\, are strongly determined by the properties of the extracellular matrix (ECM)\, including its mechanical rigidity and the density and distribution of its ligands. In this talk\, I will explain how we combine molecular biology\, biophysical measurements\, and theoretical modelling to understand the mechanisms by which cells sense and respond to matrix properties. \nI will discuss how the properties under force of integrin-ECM bonds\, and of the adaptor protein talin\, drive and regulate matrix sensing. I will further discuss how this sensing can be understood through a computational molecular clutch model\, which can quantitatively predict the role of integrins\, talin\, myosin\, and ECM receptors\, and their effect on cell response. Finally\, I will analyze how signals triggered by rigidity at cell-ECM adhesions are transmitted to the nucleus\, leading to transcriptional regulation. \nThe seminar will take place online at the GoToMeeting Platform \nKnow more about Pere Roca-Cusachs’ research here
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-pere-roca-cusachs/
LOCATION:IBEC
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200605T100000
DTEND;TZID=Europe/Madrid:20200605T120000
DTSTAMP:20260403T211323
CREATED:20200504T102718Z
LAST-MODIFIED:20200602T070514Z
UID:73835-1591351200-1591358400@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Benedetta Bolognesi
DESCRIPTION:Deep mutagenesis to understand Protein Phase Transitions\n \nBenedetta Bolognesi \, IBEC \nSpecific insoluble protein aggregates are the hallmarks of many neurodegenerative diseases. Whether the protein aggregates themselves or other forms of the proteins are toxic to cells is still unclear in many of these diseases. This lack of understanding of the causes of cellular toxicity is reflected in the general failure of multiple therapeutic approaches so far attempted. The causes of this rely mainly on the lack of systematic approaches able to estimate in parallel the effect of mutations on cell viability as well as on protein conformation. Our lab uses deep mutagenesis as a systematic and unbiased approach to identify and investigate the toxic species of proteins. \nIn this seminar I will explain how we used this approach to report on the toxicity of thousands of protein sequences and how\, more recently\, we adapted this method to track more specific biochemical processes\, such as amyloid nucleation. Overall\, the results I will discuss demonstrate that deep mutagenesis is a powerful approach to study intrinsically disordered proteins and also illustrate that it can be used to genetically validate assays as discovery platforms. \nThe seminar will take place online at the GoToMeeting Platform \nKnow more about Benedetta Bolognesi’s research here
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-benedetta-bolognesi/
CATEGORIES:IBEC Seminar
ORGANIZER;CN="IBEC":MAILTO:www.ibecbarcelona.eu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200529T100000
DTEND;TZID=Europe/Madrid:20200529T120000
DTSTAMP:20260403T211323
CREATED:20200504T102344Z
LAST-MODIFIED:20200525T070522Z
UID:73832-1590746400-1590753600@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Giuseppe Battaglia
DESCRIPTION:Bionics at the molecular level: copying Nature to control Nature\n\n\nGiuseppe Battaglia \, IBEC \n\nA very established approach in medicine involves the replacement of organs or other malfunctioning body parts by synthetic versions\, engineered to mimic (or even augment it\, if you allow the sci-fi digression) the original function. Bionics is a very established medical discipline where engineering spouses the life sciences\, creating exquisite combinations. With the help of nanoscience and nanotechnology\, we can now push such an effort down to the molecular level. In our group\, we fabricate synthetic surrogates of trafficking vesicles\, viruses and\, one day perhaps\, even a whole cell. Such molecular bionic units offer more efficient solutions to deliver drugs\, to probe life at the nanoscale\, and to act as a model to understand biological complexity. \n\n\nOur efforts are intrinsically multidisciplinary\, and we mix chemistry\, physics and biology in all we do. We typically start studying biological complexity\, with a strong focus on transport\, trafficking and multivalent interactions (Physical Biology). To help this\, we develop new tools to look at biological systems in four dimensions capturing life’s spatiotemporal patterns (Microscopy). We thus apply a constructionist approach where we mimic biological complexity in the form of design principles such as compartmentalisation\, multivalency and taxis\, to produce functional units from simple building blocks and their interactions (Molecular Engineering).​ Finally\, we apply the resulting constructs to tackle disorders such as cancer\, neurodegeneration\, inflammation\, and infections (Nanomedicine). \n\n\nToday\, I start introducing our research activities giving a few examples of each segment\, to eventually focus my seminar on one of the latest and most exciting developments\, our understanding of multivalent interaction and how these control crucial biological processes\, such as cellular selectivity and trafficking. \n\nThe seminar will take place online at the GoToMeeting Platform \nKnow more about Giuseppe Battaglia’s research here
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-giuseppe-battaglia/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200520T093000
DTEND;TZID=Europe/Madrid:20200520T133000
DTSTAMP:20260403T211323
CREATED:20200430T105230Z
LAST-MODIFIED:20200506T110053Z
UID:73809-1589967000-1589981400@ibecbarcelona.eu
SUMMARY:Research4Talent
DESCRIPTION:On Wednesday 20th May we’ll open our doors virtually to UNDERGRADUATE & MASTER’s students interested in a research career\n \nThe day is a chance for you to talk to our researchers and ask them questions about their day-to-day work in the lab\, career paths\, work-life balance\, mobility etc\, as well as a visit to our labs. \nIn 2019 IBEC signed more that 145 internship agreements for Undergraduate and Master Students with a wide range of national and international universities. \nThis year’s edition will be held virtually. If you are interested in IBEC’s fifth edition of reSEARCH4TALENT please stay connected\, we will soon provide more info with the links to acces the event. \nVisit the website here
URL:https://ibecbarcelona.eu/event/research4talent-3/
CATEGORIES:Outreach / Fair / Festival
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200515T100000
DTEND;TZID=Europe/Madrid:20200515T120000
DTSTAMP:20260403T211323
CREATED:20200504T102025Z
LAST-MODIFIED:20200508T102953Z
UID:73823-1589536800-1589544000@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Gabriel Gomila
DESCRIPTION:Multiscale approach to bioelectricity\n \nGabriel Gomila \, IBEC \nUnderstanding how electricity is generated and propagated in living systems is key to understand many physiological processes and to develop medical instruments for diagnosis\, monitoring and therapy. \nIn this seminar I will present the multiscale approach to bioelectricity developed in our research group at IBEC\, which covers from multicellular systems to single biomolecules\, with an emphasis on passive electrical properties. Topics will include novel devices for electrophysiological recordings\, novel routes and structures for extracellular electron transfer in bacterial cells\, on-chip impedance flow cytometry\, label-free electrical methods for microbiology and nanoscale electrical mapping of single cells. \nThe seminar will take place online at the GoToMeeting Platform \nKnow more about Gabriel Gomila’s research here
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-gabriel-gomila/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200508T100000
DTEND;TZID=Europe/Madrid:20200508T120000
DTSTAMP:20260403T211323
CREATED:20200421T095637Z
LAST-MODIFIED:20200429T141022Z
UID:73634-1588932000-1588939200@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Elena Martínez
DESCRIPTION:Development of biomimetic models of intestinal tissue: guiding cellular self-organization through biofabrication techniques\n\nElena Martínez \, IBEC \nEpithelial tissues contain three-dimensional (3D) microstructures that guide cell self-organization at the tissue level. In the small intestine\, crypts and finger-like villi microstructures improve its absorbance function\, provides specific microenvironments and compartmentalizes cell types. Despite its physiological relevance\, tissue architecture and multicellular population are neglected in the standard in vitro models\, thus compromising their predictive capabilities. Our efforts in addressing these shortcomings by including key elements to mimic the native tissue in vitro will be discussed in this talk. First\, this will include strategies to promote cell’s self-organization capabilities giving rise to crypt-villus domains on 2D monolayers\, and strategies to engineer cell spatial positioning through micropatterning. Then\, our approach to include the 3D architecture of the tissue will be addressed. In here\, light-based biofabrication techniques to produce 3D villus-like structures will be discussed. Finally\, I will introduce our biofabrication proposal to produce tissue engineered models that include the epithelial and the stromal compartments. Improving the prediction capabilities of cell-based assays is a growing strategy to lead to more efficient drug development processes. As 2D-based systems are showing their limits\, new 3D strategies are gaining acceptance among the scientific community. Our approaches aim to further accelerate this trend by providing feasible strategies to routinely incorporate 3D multicellular structures at the tissue level in cell culture systems. \nThe seminar will take place online at the GoToMeeting Platform \nKnow more about Elena Martínez’s research here
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-elena-martinez/
CATEGORIES:IBEC Seminar
ORGANIZER;CN="IBEC":MAILTO:www.ibecbarcelona.eu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200428T160000
DTEND;TZID=Europe/Madrid:20200428T180000
DTSTAMP:20260403T211323
CREATED:20200421T075141Z
LAST-MODIFIED:20200421T075153Z
UID:73630-1588089600-1588096800@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Samuel Sánchez
DESCRIPTION:BioEngineering Hybrid Robotic Machines: from nanobots to 3D Bioprinted Robots\n \nSamuel Sánchez \, IBEC \nThe combination of biological components and artificial ones emerges into what we called hybrid machines/bots/robots. Here\, I will present two types of hybrid systems that we are currently developing in our lab which span across different length scales\, from a few nanometers to centimeters. \nAlike bacteria or small swimmers found in nature\, these artificial nanobots convert bio-available fuels to generate propulsion force to swim at the nanoscale. One of the dreams in nanotechnology is to engineer small vehicles which can eventually be applied in vivo for medical purposes. In the first part of my talk\, I will present how we bioengineer our hybrid nanobots combining the best from the two worlds: biology (enzymes) and (nano)technology (nano- micro-particles) providing swimming capabilities\, biocompatibility\, remote control\, multifunctionality and actuation. I will present some of the proof-of-concept applications such as the efficient transport of drugs into cancer cells and spheroids\, sensing capabilities and the use of molecular imaging techniques for their tracking and localization both in vitro and in vivo. \nIn the second part of my talk\, I will present the 3D bioprinting technique to fabricate hybrid 3D BIOBOTS which provides flexibility\, scalability\, rapid prototyping and simplicity. This technique has emerged as a powerful tool for the development of functional three-dimensional tissues and\, in particular\, skeletal muscle. By electrical stimulation\, we studied the adaptability of 3D hybrid Robots after long-term trainings and the force evolution during the trainings together with the dynamic gene expression. Two types of devices are bioengineered in our lab: (i) 3D Actuators which useful force measurement platform for drug screening against dystrophies and (ii) 3D BIOBOTS that can be a next generation of living soft robotics systems with swimming capabilities. \nThe seminar will take place online at the GoToMeeting Platform \nKnow more about Samuel Sánchez’s research here
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-samuel-sanchez/
CATEGORIES:IBEC Seminar
ORGANIZER;CN="IBEC":MAILTO:www.ibecbarcelona.eu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200421T160000
DTEND;TZID=Europe/Madrid:20200421T170000
DTSTAMP:20260403T211323
CREATED:20200415T101113Z
LAST-MODIFIED:20200415T101223Z
UID:73449-1587484800-1587488400@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Lorenzo Albertazzi
DESCRIPTION:A super-resolved look at nanomedicine\n \nLorenzo Albertazzi \, IBEC \nNanomaterials revolutionized the field of biomedicine introducing innovative approaches towards drug delivery\, molecular imaging\, regenerative medicine and biosensing. However\, despite the large investments in nanotechnology the translation into clinical applications is still unsatisfactory. One of the main reasons is the lack of knowledge about the behavior of nanostructures in the biological environment that makes the rational design of effective materials extremely challenging. \nThe main aim of our group is to use advanced microscopy techniques to understand the interactions of nanomaterials with living matter and to exploit this information to design novel devices for biomedical applications with a particular focus on drug delivery. To this goal we employ innovative optical imaging techniques such as super resolution microscopy to visualize and understand the molecular interactions of nanomaterials with their cellular targets in unprecedented detail. Super resolution microscopy techniques such as stochastic optical reconstruction microscopy (STORM) and point accumulation for imaging in nanoscale topography (PAINT) offer nanometric resolution and multicolor ability\, therefore they are ideal tools to study nano-sized multicomponent functional objects in vitro and in cells. This allows to get a closer “look” at the mechanisms of the key phenomena responsible for device performances such as particle stability\, protein corona and targeting. The fundamental knowledge acquired will pave the way towards the “microscopy-guided” design of novel nanomaterials for drug and gene delivery. \nThe seminar will take place online at the GoToMeeting Platform \nKnow more about Lorenzo Albertazzi’s research here
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-lorenzo-albertazzi/
CATEGORIES:IBEC Seminar
ORGANIZER;CN="IBEC":MAILTO:www.ibecbarcelona.eu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200417T100000
DTEND;TZID=Europe/Madrid:20200417T120000
DTSTAMP:20260403T211323
CREATED:20200409T075542Z
LAST-MODIFIED:20200414T111359Z
UID:73222-1587117600-1587124800@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Javier Ramón
DESCRIPTION:Bioprinting methods for organ-on-a-chip applications\n \nJavier Ramón \, IBEC \nEngineered tissues in three-dimensional (3D) cell culture platforms that resemble the complex native structure and organization can be used as in vitro models to study tissues physiology and metabolism. Our technology allows us to develop a new platform to model metabolic and muscle diseases in vitro in order to study its response to candidate therapeutics and to better understand disease mechanisms of pathogenesis. To this end\, we monitor the secretion of disease-associated biomarker proteins and metabolites. \nHere\, we present 3D skeletal muscle constructs\, fabricated by encapsulating C2C12 cells and pancreatic mouse islets in a photocrosslinkable Gelatin Methacrylate (GelMA) and Carboxymethylcellulose Methacrylate (GelMA:CMCMA) hydrogel and cryogel scaffolds. These scaffolds present a microgrooved topography that promotes cell alignment and differentiation. These 3D tissues are integrated with biosensors for in situ monitorization of cytokines and hormones released under different external stimuli\, toxins\, drugs or electrical stimulation. \nWe have obtained a new platform to study the evolution of congenital muscle diseases\, specifically myotonic dystrophy 1 and evaluate the functional tissues by metabolic and gene expression analysis. Monitor the secretion of biomarkers proteins\, metabolites\, and the glycolysis pathway of muscle tissues for different drug candidates. Discussion: This platform has been tested with different drugs assays and represent a step toward the goal of producing in vitro drug testing systems for medical and pharmaceutical industry applications. Finally\, such “multi tissue-on-a-chip” devices can be fabricated using patient’s own cells as a major step toward personalized medicine. \nThe seminar will take place online at the GoToMeeting Platform \nKnow more about Javier Ramón’s research here
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-javier-ramon/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200305T100000
DTEND;TZID=Europe/Madrid:20200305T130000
DTSTAMP:20260403T211323
CREATED:20200302T115748Z
LAST-MODIFIED:20200302T115748Z
UID:71933-1583402400-1583413200@ibecbarcelona.eu
SUMMARY:Visita/Taller
DESCRIPTION:Mecanobiologia : les cèl·lules fan forces\nEl cos humà està constantment sotmès a forces físiques; quan et fas una ferida\, les cèl·lules del teixit circumdant apliquen forces per sanar l’àrea danyada. De la mateixa manera\, les cèl·lules canceroses apliquen forces per escampar-se a altres parts sanes del cos en forma de metàstasi. \nEls investigadors de l’IBEC utilitzen les eines\, tecnologies i tècniques de la bioenginyeria per comprendre el comportament mecànic de les cèl·lules i les seves interaccions amb el microentorn\, així com els mecanismes dinàmics que intervenen en la cicatrització de teixits\, la morfogènesi i la invasió cel·lular col·lectiva en el càncer. \nEn aquest taller els estudiants coneixeran els darrers avenços en mecanobiologia de la mà d’investigadors del nostre centre. A més\, podran posar en pràctica alguns dels principis d’aquesta jove disciplina. \nEscola: IPSE
URL:https://ibecbarcelona.eu/event/visita-taller/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:Outreach / Fair / Festival
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200228T100000
DTEND;TZID=Europe/Madrid:20200228T120000
DTSTAMP:20260403T211323
CREATED:20200221T110843Z
LAST-MODIFIED:20200221T110843Z
UID:96627-1582884000-1582891200@ibecbarcelona.eu
SUMMARY:PhD Discussions Sessions: Xarxa Quiroga and Adrián López
DESCRIPTION:Biochemical responses to cell membrane mechanical remodelling\nXarxa Quiroga\, Cellular and molecular mechanobiology\nIn a range of physiological processes\, from extravasation to endocytosis\, cells are constantly submitted to morphological changes\, which eventually entail plasma membrane reshaping and adaptation. This remodelling could be harnessed by cells to detect and respond to shape changes\, enabling mechanosensing mechanisms. However\, how this occurs is still largely unknown.\nTo increase our understanding on how such process can happen\, we have engineered a cell-stretching system that allows us to induce controlled plasma membrane remodelling while monitoring the whole process with the help of a microscope.\nBy using this set up\, we have found that cell de-stretch triggers the formation of transient membrane evaginations whose resorption is actively regulated by BAR protein recruitment and actin polymerisation. The described process may be the first part of a molecular cascade used by cells in response to stretch. \n\nDevelopment of Microphysiological Systems for the Evaluation of Regenerative Therapies\nAdrián López\, Biomaterials for Regenerative Therapies\nThe modelling of human organs has long been a task for scientist in order to lower the costs of therapeutic development and understand the pathological onset of human disease. Animal models remain the gold standard for drug discovery\, despite their widely recognized limitations such as their marked differences with humans in terms of genetics and etiology or their high cost. \nDuring the last decade\, the advancements in tissue engineering and microfabrication gave rise to innovative models known as organs-on-a-chip or microphysiological systems\, which aim to build functional miniaturized tissues in vitro that closely mimic the actual in vivo microenvironment. In this work\, we will present two microphysiological platforms that we are developing with the goal of understanding and evaluating biomaterial-based regenerative therapies. The first model is aimed at replicating the bone healing microenvironment to evaluate the angiogenic potential of calcium-releasing scaffolds. The second model will be focused on the generation of an ischemic injury on a physiologically relevant cardiac tissue to test if lactate-releasing scaffolds are able to stimulate cardiac tissue regeneration.
URL:https://ibecbarcelona.eu/event/phd-discussions-sessions-xarxa-quiroga-and-adrian-lopez-2/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:PhD Discussions Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200228T100000
DTEND;TZID=Europe/Madrid:20200228T120000
DTSTAMP:20260403T211323
CREATED:20200221T110843Z
LAST-MODIFIED:20200221T110843Z
UID:96632-1582884000-1582891200@ibecbarcelona.eu
SUMMARY:PhD Discussions Sessions: Xarxa Quiroga and Adrián López
DESCRIPTION:Biochemical responses to cell membrane mechanical remodelling\nXarxa Quiroga\, Cellular and molecular mechanobiology\nIn a range of physiological processes\, from extravasation to endocytosis\, cells are constantly submitted to morphological changes\, which eventually entail plasma membrane reshaping and adaptation. This remodelling could be harnessed by cells to detect and respond to shape changes\, enabling mechanosensing mechanisms. However\, how this occurs is still largely unknown.\nTo increase our understanding on how such process can happen\, we have engineered a cell-stretching system that allows us to induce controlled plasma membrane remodelling while monitoring the whole process with the help of a microscope.\nBy using this set up\, we have found that cell de-stretch triggers the formation of transient membrane evaginations whose resorption is actively regulated by BAR protein recruitment and actin polymerisation. The described process may be the first part of a molecular cascade used by cells in response to stretch. \n\nDevelopment of Microphysiological Systems for the Evaluation of Regenerative Therapies\nAdrián López\, Biomaterials for Regenerative Therapies\nThe modelling of human organs has long been a task for scientist in order to lower the costs of therapeutic development and understand the pathological onset of human disease. Animal models remain the gold standard for drug discovery\, despite their widely recognized limitations such as their marked differences with humans in terms of genetics and etiology or their high cost. \nDuring the last decade\, the advancements in tissue engineering and microfabrication gave rise to innovative models known as organs-on-a-chip or microphysiological systems\, which aim to build functional miniaturized tissues in vitro that closely mimic the actual in vivo microenvironment. In this work\, we will present two microphysiological platforms that we are developing with the goal of understanding and evaluating biomaterial-based regenerative therapies. The first model is aimed at replicating the bone healing microenvironment to evaluate the angiogenic potential of calcium-releasing scaffolds. The second model will be focused on the generation of an ischemic injury on a physiologically relevant cardiac tissue to test if lactate-releasing scaffolds are able to stimulate cardiac tissue regeneration.
URL:https://ibecbarcelona.eu/event/phd-discussions-sessions-xarxa-quiroga-and-adrian-lopez-2/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:PhD Discussions Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200228T100000
DTEND;TZID=Europe/Madrid:20200228T120000
DTSTAMP:20260403T211323
CREATED:20200221T110843Z
LAST-MODIFIED:20200221T110843Z
UID:96629-1582884000-1582891200@ibecbarcelona.eu
SUMMARY:PhD Discussions Sessions: Xarxa Quiroga and Adrián López
DESCRIPTION:Biochemical responses to cell membrane mechanical remodelling\nXarxa Quiroga\, Cellular and molecular mechanobiology\nIn a range of physiological processes\, from extravasation to endocytosis\, cells are constantly submitted to morphological changes\, which eventually entail plasma membrane reshaping and adaptation. This remodelling could be harnessed by cells to detect and respond to shape changes\, enabling mechanosensing mechanisms. However\, how this occurs is still largely unknown.\nTo increase our understanding on how such process can happen\, we have engineered a cell-stretching system that allows us to induce controlled plasma membrane remodelling while monitoring the whole process with the help of a microscope.\nBy using this set up\, we have found that cell de-stretch triggers the formation of transient membrane evaginations whose resorption is actively regulated by BAR protein recruitment and actin polymerisation. The described process may be the first part of a molecular cascade used by cells in response to stretch. \n\nDevelopment of Microphysiological Systems for the Evaluation of Regenerative Therapies\nAdrián López\, Biomaterials for Regenerative Therapies\nThe modelling of human organs has long been a task for scientist in order to lower the costs of therapeutic development and understand the pathological onset of human disease. Animal models remain the gold standard for drug discovery\, despite their widely recognized limitations such as their marked differences with humans in terms of genetics and etiology or their high cost. \nDuring the last decade\, the advancements in tissue engineering and microfabrication gave rise to innovative models known as organs-on-a-chip or microphysiological systems\, which aim to build functional miniaturized tissues in vitro that closely mimic the actual in vivo microenvironment. In this work\, we will present two microphysiological platforms that we are developing with the goal of understanding and evaluating biomaterial-based regenerative therapies. The first model is aimed at replicating the bone healing microenvironment to evaluate the angiogenic potential of calcium-releasing scaffolds. The second model will be focused on the generation of an ischemic injury on a physiologically relevant cardiac tissue to test if lactate-releasing scaffolds are able to stimulate cardiac tissue regeneration.
URL:https://ibecbarcelona.eu/event/phd-discussions-sessions-xarxa-quiroga-and-adrian-lopez-2/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:PhD Discussions Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200228T100000
DTEND;TZID=Europe/Madrid:20200228T120000
DTSTAMP:20260403T211323
CREATED:20200221T110843Z
LAST-MODIFIED:20200221T110843Z
UID:71615-1582884000-1582891200@ibecbarcelona.eu
SUMMARY:PhD Discussions Sessions: Xarxa Quiroga and Adrián López
DESCRIPTION:Biochemical responses to cell membrane mechanical remodelling\nXarxa Quiroga\, Cellular and molecular mechanobiology\nIn a range of physiological processes\, from extravasation to endocytosis\, cells are constantly submitted to morphological changes\, which eventually entail plasma membrane reshaping and adaptation. This remodelling could be harnessed by cells to detect and respond to shape changes\, enabling mechanosensing mechanisms. However\, how this occurs is still largely unknown.\nTo increase our understanding on how such process can happen\, we have engineered a cell-stretching system that allows us to induce controlled plasma membrane remodelling while monitoring the whole process with the help of a microscope.\nBy using this set up\, we have found that cell de-stretch triggers the formation of transient membrane evaginations whose resorption is actively regulated by BAR protein recruitment and actin polymerisation. The described process may be the first part of a molecular cascade used by cells in response to stretch. \n\nDevelopment of Microphysiological Systems for the Evaluation of Regenerative Therapies\nAdrián López\, Biomaterials for Regenerative Therapies\nThe modelling of human organs has long been a task for scientist in order to lower the costs of therapeutic development and understand the pathological onset of human disease. Animal models remain the gold standard for drug discovery\, despite their widely recognized limitations such as their marked differences with humans in terms of genetics and etiology or their high cost. \nDuring the last decade\, the advancements in tissue engineering and microfabrication gave rise to innovative models known as organs-on-a-chip or microphysiological systems\, which aim to build functional miniaturized tissues in vitro that closely mimic the actual in vivo microenvironment. In this work\, we will present two microphysiological platforms that we are developing with the goal of understanding and evaluating biomaterial-based regenerative therapies. The first model is aimed at replicating the bone healing microenvironment to evaluate the angiogenic potential of calcium-releasing scaffolds. The second model will be focused on the generation of an ischemic injury on a physiologically relevant cardiac tissue to test if lactate-releasing scaffolds are able to stimulate cardiac tissue regeneration.
URL:https://ibecbarcelona.eu/event/phd-discussions-sessions-xarxa-quiroga-and-adrian-lopez/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:PhD Discussions Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200227T110000
DTEND;TZID=Europe/Madrid:20200227T130000
DTSTAMP:20260403T211324
CREATED:20200218T121211Z
LAST-MODIFIED:20200220T082610Z
UID:71495-1582801200-1582808400@ibecbarcelona.eu
SUMMARY:NANO Rare Disease Day 2020
DESCRIPTION:Nano Rare Diseases Day es un evento organizado en el marco del Día Mundial de las Enfermedades Minoritarias donde se darán a conocer las últimas innovaciones en materia de Nanomedicina para el tratamiento y diagnóstico de dichas enfermedades\, con temas que van desde el diagnóstico precoz\, la liberación controlada de fármacos o el desarrollo de nuevas terapia\nDurante esta jornada\, expertos en Nanomedicina de diferentes campos -investigación\, empresa\, práctica clínica\, autoridades sanitarias\, pacientes\, etc.-\,  expondrán los últimos avances y nos darán la oportunidad de descubrir el generador de progreso que la Nanomedicina significa para la salud como creador de nuevas oportunidades en el diagnóstico y el tratamiento de las enfermedades minoritarias. \nInscripciones abiertas \n 
URL:https://ibecbarcelona.eu/event/nano-rare-diseade-day-2020/
LOCATION:Auditori J. Plaza\, Hospital Sant Joan de Déu\, Passeig de Sant Joan de Déu\, 2\, Esplugues de Llobregat\, Barcelona\, 08950 \, Spain
CATEGORIES:External symposium / conference / congress
ATTACH;FMTTYPE=image/png:https://ibecbarcelona.eu/wp-content/uploads/2020/02/rarediseasesday_banner-0x0-1.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200227T110000
DTEND;TZID=Europe/Madrid:20200227T130000
DTSTAMP:20260403T211324
CREATED:20200218T121211Z
LAST-MODIFIED:20200218T121211Z
UID:96624-1582801200-1582808400@ibecbarcelona.eu
SUMMARY:NANO Rare Disease Day 2020
DESCRIPTION:Nano Rare Diseases Day es un evento organizado en el marco del Día Mundial de las Enfermedades Minoritarias donde se darán a conocer las últimas innovaciones en materia de Nanomedicina para el tratamiento y diagnóstico de dichas enfermedades\, con temas que van desde el diagnóstico precoz\, la liberación controlada de fármacos o el desarrollo de nuevas terapias\nDurante esta jornada\, expertos en Nanomedicina de diferentes campos -investigación\, empresa\, práctica clínica\, autoridades sanitarias\, pacientes\, etc.-\,  expondrán los últimos avances y nos darán la oportunidad de descubrir el generador de progreso que la Nanomedicina significa para la salud como creador de nuevas oportunidades en el diagnóstico y el tratamiento de las enfermedades minoritarias. \nInscripciones abiertas \n 
URL:https://ibecbarcelona.eu/event/nano-rare-diseade-day-2020-3/
LOCATION:Auditori J. Plaza\, Hospital Sant Joan de Déu\, Passeig de Sant Joan de Déu\, 2\, Esplugues de Llobregat\, Barcelona\, 08950 \, Spain
CATEGORIES:External symposium / conference / congress
ATTACH;FMTTYPE=image/png:https://ibecbarcelona.eu/wp-content/uploads/2020/02/rarediseasesday_banner-0x0-1.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200227T110000
DTEND;TZID=Europe/Madrid:20200227T130000
DTSTAMP:20260403T211324
CREATED:20200218T121211Z
LAST-MODIFIED:20200218T121211Z
UID:96622-1582801200-1582808400@ibecbarcelona.eu
SUMMARY:NANO Rare Disease Day 2020
DESCRIPTION:Nano Rare Diseases Day es un evento organizado en el marco del Día Mundial de las Enfermedades Minoritarias donde se darán a conocer las últimas innovaciones en materia de Nanomedicina para el tratamiento y diagnóstico de dichas enfermedades\, con temas que van desde el diagnóstico precoz\, la liberación controlada de fármacos o el desarrollo de nuevas terapias\nDurante esta jornada\, expertos en Nanomedicina de diferentes campos -investigación\, empresa\, práctica clínica\, autoridades sanitarias\, pacientes\, etc.-\,  expondrán los últimos avances y nos darán la oportunidad de descubrir el generador de progreso que la Nanomedicina significa para la salud como creador de nuevas oportunidades en el diagnóstico y el tratamiento de las enfermedades minoritarias. \nInscripciones abiertas \n 
URL:https://ibecbarcelona.eu/event/nano-rare-diseade-day-2020-2/
LOCATION:Auditori J. Plaza\, Hospital Sant Joan de Déu\, Passeig de Sant Joan de Déu\, 2\, Esplugues de Llobregat\, Barcelona\, 08950 \, Spain
CATEGORIES:External symposium / conference / congress
ATTACH;FMTTYPE=image/png:https://ibecbarcelona.eu/wp-content/uploads/2020/02/rarediseasesday_banner-0x0-1.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200227T110000
DTEND;TZID=Europe/Madrid:20200227T130000
DTSTAMP:20260403T211324
CREATED:20200218T121211Z
LAST-MODIFIED:20200218T121211Z
UID:96626-1582801200-1582808400@ibecbarcelona.eu
SUMMARY:NANO Rare Disease Day 2020
DESCRIPTION:Nano Rare Diseases Day es un evento organizado en el marco del Día Mundial de las Enfermedades Minoritarias donde se darán a conocer las últimas innovaciones en materia de Nanomedicina para el tratamiento y diagnóstico de dichas enfermedades\, con temas que van desde el diagnóstico precoz\, la liberación controlada de fármacos o el desarrollo de nuevas terapia\nDurante esta jornada\, expertos en Nanomedicina de diferentes campos -investigación\, empresa\, práctica clínica\, autoridades sanitarias\, pacientes\, etc.-\,  expondrán los últimos avances y nos darán la oportunidad de descubrir el generador de progreso que la Nanomedicina significa para la salud como creador de nuevas oportunidades en el diagnóstico y el tratamiento de las enfermedades minoritarias. \nInscripciones abiertas \n 
URL:https://ibecbarcelona.eu/event/nano-rare-diseade-day-2020-4/
LOCATION:Auditori J. Plaza\, Hospital Sant Joan de Déu\, Passeig de Sant Joan de Déu\, 2\, Esplugues de Llobregat\, Barcelona\, 08950 \, Spain
CATEGORIES:External symposium / conference / congress
ATTACH;FMTTYPE=image/png:https://ibecbarcelona.eu/wp-content/uploads/2020/02/rarediseasesday_banner-0x0-1.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200227T080000
DTEND;TZID=Europe/Madrid:20200227T170000
DTSTAMP:20260403T211324
CREATED:20200227T162601Z
LAST-MODIFIED:20200227T162601Z
UID:71805-1582790400-1582822800@ibecbarcelona.eu
SUMMARY:Taula rodona: el futur dels transplantaments
DESCRIPTION:Javier Ramón participará a la taula rodona: quin és el futur dels transplantaments?\nOrganitzat pel màster de comunicació científica\, mèdica i ambiental de la UPF-BSM.
URL:https://ibecbarcelona.eu/event/taula-rodona-el-futur-dels-transplantaments-2/
CATEGORIES:Outreach / Fair / Festival
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200226T183000
DTEND;TZID=Europe/Madrid:20200226T200000
DTSTAMP:20260403T211324
CREATED:20200227T161721Z
LAST-MODIFIED:20200227T161721Z
UID:71804-1582741800-1582747200@ibecbarcelona.eu
SUMMARY:Taula rodona: el futur dels transplantaments
DESCRIPTION:Javier Ramón participará a la taula rodona: quin és el futur dels transplantaments?\nOrganitzat pel màster de comunicació científica\, mèdica i ambiental de la UPF-BSM.
URL:https://ibecbarcelona.eu/event/taula-rodona-el-futur-dels-transplantaments/
LOCATION:UPF-BSM\, Calle Balmes 132 \, Barcelona\, 08008
CATEGORIES:Outreach / Fair / Festival
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200224T113000
DTEND;TZID=Europe/Madrid:20200224T133000
DTSTAMP:20260403T211324
CREATED:20200205T152838Z
LAST-MODIFIED:20200205T154546Z
UID:71058-1582543800-1582551000@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Martí Checa
DESCRIPTION:A Novel Scanning Probe Microscopy technique to study the nanoscale electrical properties of cells\nMartí Checa\, Nanoscale bioelectrical characterization group \nThe goal of this work of thesis is the study of electrical properties in cells. That is the study of how they can conduct electricity\, accumulate charges\, or polarize. Experimental techniques able to measure electrical properties of complex heterogeneous samples (like cells) with excellent spatial resolution are needed to accomplish such characterization at the single-cell level (microscale) or even at the subcellular level (nanoscale). During this work of thesis\, a new experimental technique named “Scanning Dielectric Force Volume Microscopy (SDFVM)” has been developed together with the theoretical modeling for its understanding when operated in a liquid environment. \nThe technique has been validated with known samples (both in dry and liquid) and applied to many different nanometric systems of interest. The first full map of the local dielectric constant of a prokaryotic cell in dry conditions has been obtained with unparalleled accuracy and spatial resolution\, demonstrating its capability for label-free composition and structural mapping. Moreover\, the method has been applied to liquid environment\, obtaining the first-ever local dielectric contrast in fixed eukaryotic cells. Furthermore\, the first preliminary results in living cells have also been shown. SDFVM is expected to have an important impact not only in Life Sciences but also in Material Science\, where the mapping of the dielectric properties of samples showing complex nanoscale topographies is often needed. \n  \n  \n 
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-marti-checa/
LOCATION:Eduard Fontseré – Facultat de Física de la UB
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200224T113000
DTEND;TZID=Europe/Madrid:20200224T133000
DTSTAMP:20260403T211324
CREATED:20200205T152838Z
LAST-MODIFIED:20200205T152838Z
UID:96619-1582543800-1582551000@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Martí Checa
DESCRIPTION:A Novel Scanning Probe Microscopy technique to study the nanoscale electrical properties of cells\nMartí Checa\, Nanoscale bioelectrical characterization group \nThe goal of this work of thesis is the study of electrical properties in cells. That is the study of how they can conduct electricity\, accumulate charges\, or polarize. Experimental techniques able to measure electrical properties of complex heterogeneous samples (like cells) with excellent spatial resolution are needed to accomplish such characterization at the single-cell level (microscale) or even at the subcellular level (nanoscale). During this work of thesis\, a new experimental technique named “Scanning Dielectric Force Volume Microscopy (SDFVM)” has been developed together with the theoretical modeling for its understanding when operated in a liquid environment. \nThe technique has been validated with known samples (both in dry and liquid) and applied to many different nanometric systems of interest. The first full map of the local dielectric constant of a prokaryotic cell in dry conditions has been obtained with unparalleled accuracy and spatial resolution\, demonstrating its capability for label-free composition and structural mapping. Moreover\, the method has been applied to liquid environment\, obtaining the first-ever local dielectric contrast in fixed eukaryotic cells. Furthermore\, the first preliminary results in living cells have also been shown. SDFVM is expected to have an important impact not only in Life Sciences but also in Material Science\, where the mapping of the dielectric properties of samples showing complex nanoscale topographies is often needed. \n  \n  \n 
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-marti-checa-3/
LOCATION:Eduard Fontseré – Facultat de Física de la UB
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200224T113000
DTEND;TZID=Europe/Madrid:20200224T133000
DTSTAMP:20260403T211324
CREATED:20200205T152838Z
LAST-MODIFIED:20200205T152838Z
UID:96617-1582543800-1582551000@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Martí Checa
DESCRIPTION:A Novel Scanning Probe Microscopy technique to study the nanoscale electrical properties of cells\nMartí Checa\, Nanoscale bioelectrical characterization group \nThe goal of this work of thesis is the study of electrical properties in cells. That is the study of how they can conduct electricity\, accumulate charges\, or polarize. Experimental techniques able to measure electrical properties of complex heterogeneous samples (like cells) with excellent spatial resolution are needed to accomplish such characterization at the single-cell level (microscale) or even at the subcellular level (nanoscale). During this work of thesis\, a new experimental technique named “Scanning Dielectric Force Volume Microscopy (SDFVM)” has been developed together with the theoretical modeling for its understanding when operated in a liquid environment. \nThe technique has been validated with known samples (both in dry and liquid) and applied to many different nanometric systems of interest. The first full map of the local dielectric constant of a prokaryotic cell in dry conditions has been obtained with unparalleled accuracy and spatial resolution\, demonstrating its capability for label-free composition and structural mapping. Moreover\, the method has been applied to liquid environment\, obtaining the first-ever local dielectric contrast in fixed eukaryotic cells. Furthermore\, the first preliminary results in living cells have also been shown. SDFVM is expected to have an important impact not only in Life Sciences but also in Material Science\, where the mapping of the dielectric properties of samples showing complex nanoscale topographies is often needed. \n 
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-marti-checa-2/
LOCATION:Eduard Fontseré – Facultat de Física de la UB
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200224T113000
DTEND;TZID=Europe/Madrid:20200224T133000
DTSTAMP:20260403T211324
CREATED:20200205T152838Z
LAST-MODIFIED:20200205T152838Z
UID:96620-1582543800-1582551000@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Martí Checa
DESCRIPTION:A Novel Scanning Probe Microscopy technique to study the nanoscale electrical properties of cells\nMartí Checa\, Nanoscale bioelectrical characterization group \nThe goal of this work of thesis is the study of electrical properties in cells. That is the study of how they can conduct electricity\, accumulate charges\, or polarize. Experimental techniques able to measure electrical properties of complex heterogeneous samples (like cells) with excellent spatial resolution are needed to accomplish such characterization at the single-cell level (microscale) or even at the subcellular level (nanoscale). During this work of thesis\, a new experimental technique named “Scanning Dielectric Force Volume Microscopy (SDFVM)” has been developed together with the theoretical modeling for its understanding when operated in a liquid environment. \nThe technique has been validated with known samples (both in dry and liquid) and applied to many different nanometric systems of interest. The first full map of the local dielectric constant of a prokaryotic cell in dry conditions has been obtained with unparalleled accuracy and spatial resolution\, demonstrating its capability for label-free composition and structural mapping. Moreover\, the method has been applied to liquid environment\, obtaining the first-ever local dielectric contrast in fixed eukaryotic cells. Furthermore\, the first preliminary results in living cells have also been shown. SDFVM is expected to have an important impact not only in Life Sciences but also in Material Science\, where the mapping of the dielectric properties of samples showing complex nanoscale topographies is often needed. \n  \n  \n 
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-marti-checa-4/
LOCATION:Eduard Fontseré – Facultat de Física de la UB
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200214T100000
DTEND;TZID=Europe/Madrid:20200214T170000
DTSTAMP:20260403T211324
CREATED:20200205T084744Z
LAST-MODIFIED:20200205T084744Z
UID:96613-1581674400-1581699600@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Marc Vendrell
DESCRIPTION:Translational chemistry\, optical imaging and precision medicine\nMarc Vendrell \, University of Edinburgh \nOptical imaging has revolutionised our understanding of how biological systems behave at the molecular level. In the last years\, my group has developed dynamic activatable fluorophores (DYNAFLUORS) as chemical tools to image the function and activity of immune cells in disease. We have used the probes to interrogate the dynamics of biology in real time and also translated some of them for clinical applications\, including first-in-human studies. My group is currently focused on creating new probes that can help us understand the roles that specific subsets of immune cells play in the tumour microenvironment and improve personalised therapeutic approaches.\nGroup website: www.dynafluors.co.uk \nMarc Vendrell graduated in Chemistry at the University of Barcelona in 2007. He then joined the Singapore Bioimaging Consortium to work with Young-Tae Chang in the design of synthetic fluorophores for optical imaging. In 2012 he started his independent career as an MRC Academic Fellow at the University of Edinburgh and is now a Senior Lecturer in Biomedical Imaging. He has over 90 publications\, including 11 patents with multiple fluorescent probes being commercialised by Merck and Biolegend and some currently undergoing clinical studies. His research has been recognised with several international awards and distinctions\, including an ERC Consolidator Grant (2017)\, the Marcial Moreno Lectureship (2018) and the SRUK Emerging Talent Award (2019). \nHe has been invited to Sílvia Pujals and Lorenzo Albertazzi
URL:https://ibecbarcelona.eu/event/ibec-seminar-marc-vendrell/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200214T100000
DTEND;TZID=Europe/Madrid:20200214T170000
DTSTAMP:20260403T211324
CREATED:20200205T084744Z
LAST-MODIFIED:20200205T084744Z
UID:96614-1581674400-1581699600@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Marc Vendrell
DESCRIPTION:Translational chemistry\, optical imaging and precision medicine\nMarc Vendrell \, University of Edinburgh \nOptical imaging has revolutionised our understanding of how biological systems behave at the molecular level. In the last years\, my group has developed dynamic activatable fluorophores (DYNAFLUORS) as chemical tools to image the function and activity of immune cells in disease. We have used the probes to interrogate the dynamics of biology in real time and also translated some of them for clinical applications\, including first-in-human studies. My group is currently focused on creating new probes that can help us understand the roles that specific subsets of immune cells play in the tumour microenvironment and improve personalised therapeutic approaches.\nGroup website: www.dynafluors.co.uk \nMarc Vendrell graduated in Chemistry at the University of Barcelona in 2007. He then joined the Singapore Bioimaging Consortium to work with Young-Tae Chang in the design of synthetic fluorophores for optical imaging. In 2012 he started his independent career as an MRC Academic Fellow at the University of Edinburgh and is now a Senior Lecturer in Biomedical Imaging. He has over 90 publications\, including 11 patents with multiple fluorescent probes being commercialised by Merck and Biolegend and some currently undergoing clinical studies. His research has been recognised with several international awards and distinctions\, including an ERC Consolidator Grant (2017)\, the Marcial Moreno Lectureship (2018) and the SRUK Emerging Talent Award (2019). \nHe has been invited to Sílvia Pujals and Lorenzo Albertazzi
URL:https://ibecbarcelona.eu/event/ibec-seminar-marc-vendrell/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200214T100000
DTEND;TZID=Europe/Madrid:20200214T120000
DTSTAMP:20260403T211324
CREATED:20200130T145950Z
LAST-MODIFIED:20200130T145950Z
UID:96600-1581674400-1581681600@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Marc Vendrell
DESCRIPTION:Translational chemistry\, optical imaging and precision medicine\nMarc Vendrell \, University of Edinburgh \nOptical imaging has revolutionised our understanding of how biological systems behave at the molecular level. In the last years\, my group has developed dynamic activatable fluorophores (DYNAFLUORS) as chemical tools to image the function and activity of immune cells in disease. We have used the probes to interrogate the dynamics of biology in real time and also translated some of them for clinical applications\, including first-in-human studies. My group is currently focused on creating new probes that can help us understand the roles that specific subsets of immune cells play in the tumour microenvironment and improve personalised therapeutic approaches.\nGroup website: www.dynafluors.co.uk \nMarc Vendrell graduated in Chemistry at the University of Barcelona in 2007. He then joined the Singapore Bioimaging Consortium to work with Young-Tae Chang in the design of synthetic fluorophores for optical imaging. In 2012 he started his independent career as an MRC Academic Fellow at the University of Edinburgh and is now a Senior Lecturer in Biomedical Imaging. He has over 90 publications\, including 11 patents with multiple fluorescent probes being commercialised by Merck and Biolegend and some currently undergoing clinical studies. His research has been recognised with several international awards and distinctions\, including an ERC Consolidator Grant (2017)\, the Marcial Moreno Lectureship (2018) and the SRUK Emerging Talent Award (2019). \nHe has been invited to Sílvia Pujals and Lorenzo Albertazzi
URL:https://ibecbarcelona.eu/event/ibec-seminar-andela-saric-3/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200214T100000
DTEND;TZID=Europe/Madrid:20200214T120000
DTSTAMP:20260403T211324
CREATED:20200130T145950Z
LAST-MODIFIED:20200203T160844Z
UID:70818-1581674400-1581681600@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Marc Vendrell
DESCRIPTION:Translational chemistry\, optical imaging and precision medicine\nMarc Vendrell \, University of Edinburgh \nOptical imaging has revolutionised our understanding of how biological systems behave at the molecular level. In the last years\, my group has developed dynamic activatable fluorophores (DYNAFLUORS) as chemical tools to image the function and activity of immune cells in disease. We have used the probes to interrogate the dynamics of biology in real time and also translated some of them for clinical applications\, including first-in-human studies. My group is currently focused on creating new probes that can help us understand the roles that specific subsets of immune cells play in the tumour microenvironment and improve personalised therapeutic approaches.\nGroup website: www.dynafluors.co.uk \nMarc Vendrell graduated in Chemistry at the University of Barcelona in 2007. He then joined the Singapore Bioimaging Consortium to work with Young-Tae Chang in the design of synthetic fluorophores for optical imaging. In 2012 he started his independent career as an MRC Academic Fellow at the University of Edinburgh and is now a Senior Lecturer in Biomedical Imaging. He has over 90 publications\, including 11 patents with multiple fluorescent probes being commercialised by Merck and Biolegend and some currently undergoing clinical studies. His research has been recognised with several international awards and distinctions\, including an ERC Consolidator Grant (2017)\, the Marcial Moreno Lectureship (2018) and the SRUK Emerging Talent Award (2019). \nHe has been invited to Sílvia Pujals and Lorenzo Albertazzi
URL:https://ibecbarcelona.eu/event/ibec-seminar-andela-saric/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200211T080000
DTEND;TZID=Europe/Madrid:20200211T170000
DTSTAMP:20260403T211324
CREATED:20200227T160505Z
LAST-MODIFIED:20200227T160505Z
UID:71793-1581408000-1581440400@ibecbarcelona.eu
SUMMARY:100tífiques
DESCRIPTION:On the occasion of the International Day of Woman and Girls in Science researchers from IBEC went to different catalan schools to give a presentation of women in science to encourage all kids to study STEAM digrees. \nFurthermore\, as IBEC has a partnership with the elementary school “Escola Gayarre” within the frame of the “Magnet Projects” some of our researchers visited their classrooms and also gave an oran exposition of women in science.
URL:https://ibecbarcelona.eu/event/100tifiques/
LOCATION:IBEC\, Baldiri Reixac 10-12\, Barcelona\, 08028\, Spain
CATEGORIES:Outreach / Fair / Festival
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20200211T080000
DTEND;TZID=Europe/Madrid:20200211T170000
DTSTAMP:20260403T211324
CREATED:20200227T160505Z
LAST-MODIFIED:20200227T160505Z
UID:96634-1581408000-1581440400@ibecbarcelona.eu
SUMMARY:100tífiques
DESCRIPTION:On the occasion of the International Day of Woman and Girls in Science researchers from IBEC went to different catalan schools to give a presentation of women in science to encourage all kids to study STEAM digrees. \nFurthermore\, as IBEC has a partnership with the elementary school “Escola Gayarre” within the frame of the “Magnet Projects” some of our researchers visited their classrooms and also gave an oran exposition of women in science.
URL:https://ibecbarcelona.eu/event/100tifiques-2/
LOCATION:IBEC\, Baldiri Reixac 10-12\, Barcelona\, 08028\, Spain
CATEGORIES:Outreach / Fair / Festival
END:VEVENT
END:VCALENDAR