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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220121T100000
DTEND;TZID=Europe/Madrid:20220121T120000
DTSTAMP:20260404T004035
CREATED:20210901T151240Z
LAST-MODIFIED:20220111T080313Z
UID:86926-1642759200-1642766400@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Carlos Aleman
DESCRIPTION:Smart and multifunctional artificial materials for bioengineering\nCarlos Aleman\, Universitat Politècnica de Catalunta (UPC) \nThe research of the ” Innovation\, Modeling & Engineering in Materials” group in the field of multifunctional materials. Three\, different examples of multifunctional systems will be presented: 1) Magnetic electroconductive and self-healing PEDOT:alginate hydrogels for sensing\, drug-delivery and energy storage; 2) Self-standing PLA/PEDOT films as artificial muscles\, controlled lactate release and selective ion transport; and 3) Permanently polarized hydroxyapatite a biocatalyst for carbon and nitrogen fixation. \nCarlos Alemán graduated in Chemistry from the University of Barcelona (Spain). He received his Ph.D. from the Polytechnic University of Catalonia (UPC) in 1994\, where he was promoted to the position of Full Professor of Physical Chemistry. He was postdoctoral researcher at the ETH in Zürich (Switzerland) and visiting professor at the Università di Napoli Federico II (Italy)\, University of Twente (Holland) and Universidade Federal do Rio Grande do Sul (Brazil). Since 2003 he is the leader of the ‘‘Innovation\, Modeling & Engineering in Materials’’ (IMEM) group. His main research interests focus on conducting polymers and biopolymers with biomedical and technological (energy) applications. \nThis seminar will take place online\, using the go to meeting app
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-carlos-aleman/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220122T040000
DTEND;TZID=Europe/Madrid:20220122T173000
DTSTAMP:20260404T004036
CREATED:20220427T084206Z
LAST-MODIFIED:20220427T084206Z
UID:93892-1642824000-1642872600@ibecbarcelona.eu
SUMMARY:Núria Montserrat at "TEDxBarcelona - 8+3 charlas para vivir una vida saludable"
DESCRIPTION:Evento anual TEDxBarcelona 2022\, una jornada única donde personas extraordinarias presentarán sus ideas para vivir una vida en salud. \n\n\n\nEl evento anual consta de diferentes conferencias divididas en dos sesiones durante toda la jornada\, entre ellas\, los asistentes podrán disfrutar de una feria donde algunas empresas de Barcelona presentarán sus productos innovadores.1ª Ponencia: 16:00h – 17:30h \n\n\n\nJosé Cruset (Director de TEDxBarcelona)Chris Anderson (Curator at TED)Nuria Montserrat (ICREA Research Professor)Violeta Moizé (Profesora asociada de la UB en nutrición)Anneke Stolk (Cofundadora de Instagreen)Carlos Gonzalez y Neus Carol Gres (Proyecto AFIN)Feria y vídeos TED: 17:30h – 18:30h \n\n\n\nDan Buettner (How To Live To Be 100+)Jaime Oliver (Teach Every Child About Food)Tim Urban (Inside the mind of master procrastinator)2ª Ponencia: 18:30h – 20:00h \n\n\n\nChris Anderson (Curator at TED)Carol Blázquez (Directora de innovación y sostenibilidad en ECOALF)Lucía Hernández (Consultora para la ONU)Carlos Alcoba (Presidente de SostreCivic)María Hernández-Alcalá (CEO de Futurlife21) \n\n\n\nEntradas aquí
URL:https://ibecbarcelona.eu/event/nuria-montserrat-at-tedxbarcelona-83-charlas-para-vivir-una-vida-saludable/
CATEGORIES:External symposium / conference / congress
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220127T110000
DTEND;TZID=Europe/Madrid:20220127T140000
DTSTAMP:20260404T004036
CREATED:20220114T093409Z
LAST-MODIFIED:20220114T095350Z
UID:89934-1643281200-1643292000@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Ariadna Marín Llauradó
DESCRIPTION:Mechanical stress in curved epithelia of designed size and shape\nAriadna Marín Llauradó\, Integrative cell and tissue dynamics group \nThe function of organs such as lungs\, kidneys and mammary glands relies on the three-dimensional geometry of their epithelium. How epithelial geometry emerges from mechanical stresses remains poorly understood. To address this question systematically\, here we engineered curved epithelial monolayers of controlled size and shape and mapped their state of stress. We designed pressurized epithelia with spherical\, rectangular and ellipsoidal cross-sections. We developed a computational approach to map the stress tensor these epithelia from the measured pressure and geometry\, without assumptions of material properties.  In epithelia with spherical cross-section spanning more than one order of magnitude in radius\, we show that stress increases with areal strain in a size-independent manner. In epithelia with rectangular and ellipsoidal cross-section we found pronounced stress anisotropies consistent with asymmetric distribution tractions measured at the cell-substrate contact line. Cells tended to align with the direction of maximum principal stress\, but this alignment was non-universal and increased with monolayer anisotropy. Our study establishes how the size and shape of an epithelium depends on luminal pressure and mechanical stress. \nThis thesis defence will take place at Auditori Antoni Caparrós\, located at the Parc Científic de Barcelona\, Tower D with limited capacity\, seats will be assigned on a first come first served basis. The defence will start at 11 AM.
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-ariadna-marin-llaurado/
LOCATION:Auditori Antoni Caparrós\, PCB\, Tower D\, c/Baldiri Reixac 4-8\, Barcelona\, Spain
CATEGORIES:PhD Thesis Defence
ORGANIZER;CN="IBEC":MAILTO:www.ibecbarcelona.eu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220128T110000
DTEND;TZID=Europe/Madrid:20220128T130000
DTSTAMP:20260404T004036
CREATED:20220427T084623Z
LAST-MODIFIED:20220427T084623Z
UID:93895-1643367600-1643374800@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Andrea García Lizarribar
DESCRIPTION:Development of tunable bioinks to fabricate 3D-printed in vitro models: a special focus on skeletal muscle models with potential applications in metabolic alteration studies\n\n\n\nAndrea García Lizarribar\, Nanobioengineering group \n\n\n\nThis thesis defence will be held online using the Teams App\, you can find the link here. You can find more information here
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-andrea-garcia-lizarribar/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220201T100000
DTEND;TZID=Europe/Madrid:20220201T120000
DTSTAMP:20260404T004036
CREATED:20220427T085100Z
LAST-MODIFIED:20220427T085101Z
UID:93896-1643709600-1643716800@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Lucía Selfa Aspiroz
DESCRIPTION:Engineering human pluripotent stem cells to understand kidney development and disease\n\n\n\nLucía Selfa Aspiroz\, Pluripotency for organ regeneration group \n\n\n\nThis thesis defence will start at 10AM. If you wisth to attend to this PhD thesis defence\, you can join here via zoom.
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-lucia-selfa-aspiroz/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220204T100000
DTEND;TZID=Europe/Madrid:20220204T130000
DTSTAMP:20260404T004036
CREATED:20220427T085707Z
LAST-MODIFIED:20220427T085709Z
UID:93899-1643968800-1643979600@ibecbarcelona.eu
SUMMARY:Nanodía mundial contra el cáncer – 2022
DESCRIPTION:El Nanodía Mundial Contra el Cáncer es un evento organizado en el marco del Día Mundial contra el Cáncer donde se darán a conocer las últimas innovaciones en materia de NANOMEDICINA contra el CÁNCER\, con temas que van desde el diagnóstico precoz\, la liberación controlada de fármacos o la radioterapia con nanopartículas. \n\n\n\nUn año más\, expertos en NANOMEDICINA de diferentes campos -investigadores\, empresarios\, médicos oncólogos\, pacientes\, etc.-\,  expondrán los últimos avances y nos darán la oportunidad de descubrir el generador de progreso que la NANOMEDICINA significa para la salud como creador de nuevas oportunidades en el diagnóstico y el tratamiento del cáncer y como podemos contribuir en la misión Europea contra el cáncer. \n\n\n\nIniciado bajo el nombre de NANO WORLD CANCER DAY\, NANOMED Spain organiza la edición de este año de manera virtual con la colaboración del VHIR (Vall d’Hebron Instituto de Investigación) y el VHIO (Vall d’Hebron Instituto de Oncología).  \n\n\n\nMás información y registro aquí.
URL:https://ibecbarcelona.eu/event/nanodia-mundial-contra-el-cancer-2022/
CATEGORIES:Joint seminar / workshop / symposium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220225T100000
DTEND;TZID=Europe/Madrid:20220225T170000
DTSTAMP:20260404T004036
CREATED:20220218T094610Z
LAST-MODIFIED:20220218T094610Z
UID:90539-1645783200-1645808400@ibecbarcelona.eu
SUMMARY:PhD Discussions: Giulia Fornabaio and Shubham Tanwar
DESCRIPTION:Biomechanics of the progression of colorectal carcinomas\nGiulia Fornabaio\, Synthetic morphogenesis group \nAccording to the World Health Organization\, cancer is one of the main causes of death worldwide\, with colorectal carcinoma (CRC) being the second-leading cause of tumour related-death. The high rate of mortality of CRCs is principally attributed to the metastasis of neoplastic cells from the primary tumour to secondary organs such as the liver\, the lung and the peritoneum. These cells can disseminate either as single isolated cells or as collective clusters\, undergoing a series of molecular and cellular changes commonly known as Epithelial to Mesenchymal Transition (EMT). However\, in 2018\, Jaulin and her team described a novel modality of peritoneal metastatic spread characterized by the presence of large clusters of cancer cells\, which maintain their epithelial properties and display an outward apical polarity. These clusters of cells\, termed tumour spheres with inverted polarity (TSIPs)\, were found in peritoneal effusions of CRCs patients showing early KRAS mutation and hypermethylation of CpG Islands. \nTSIPs originate through a series of morphological changes: the first event is the sprouting of hypermethylated epithelia\, followed by their apical budding\, leading to the formation of rounded spherical clusters of cells called buds\, and the subsequent cleavage of the newly formed spheres. How cell and tissue mechanics drive this process is still unclear. To provide novel insights into this metastatic cascade\, our project aims at deciphering the biomechanical and cellular events regulating the formation of buds in colorectal cancer cell lines. Employing a combination between cellular biology techniques with biophysical methods\, we showed that this process is characterized by over-proliferation and local changes in cell adhesion\, coupled with the formation of cellular vortexes surrounding the buds. Our study demonstrates that buds development in colorectal carcinomas epithelia is governed by morphological transitions occurring entirely at multicellular level\, rather than by single cells aggregation or cell extrusion. \nImaging Functional Organic Bioelectronic Platforms at the Nanoscale\nShubham Tanwar\, Nanoscale Bioelectrical Characterization group \nIn recent years\, many organic bioelectronic platforms have emerged to bridge the signaling gap between biology and technology. Organic bioelectronic platforms based on transistor architecture\, commonly known as Electrolyte-Gated Transistors (EGTs)\, are an excellent tool to selectively sense\, record\, and monitor biological signals and states\, and convert them into measurable electrical signals.1 Biological events happening at the nanoscale are now routinely studied and characterized by a millimeter-sized transistor. However\, it is not well understood how these nanoscale events interact with the transistor’s nanoscale properties leading to a change in their macroscale response. This gap in understanding is purely due to the lack of techniques to image the electrical properties in a liquid environment. Towards this goal\, our group has adapted in-Liquid Scanning Dielectric Microscopy to unravel the inner working of EGTs at the nanoscale.2 Besides apparent topographical changes\, electrical properties\, like conductivity and interfacial capacitance\, and mechanical properties are mapped at the nanoscale in a working transistor in liquid. The vast information extracted has made it possible to correlate the nanoscale processes with the macroscale response\, offering improved understanding and the potential for substantial optimization of bioelectronic devices. \nThis PhD Discussion session will be held at Tower I\, 11th floor Baobab room\, there will be 30 avialable seats\, the free spots will be assigned on a first come first served basis.
URL:https://ibecbarcelona.eu/event/phd-discussions-giulia-fornabaio-and-shubham-tanwar-2/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220225T100000
DTEND;TZID=Europe/Madrid:20220225T170000
DTSTAMP:20260404T004036
CREATED:20220218T094610Z
LAST-MODIFIED:20220218T094610Z
UID:96527-1645783200-1645808400@ibecbarcelona.eu
SUMMARY:PhD Discussions: Giulia Fornabaio and Shubham Tanwar
DESCRIPTION:Biomechanics of the progression of colorectal carcinomas\nGiulia Fornabaio\, Synthetic morphogenesis group \nAccording to the World Health Organization\, cancer is one of the main causes of death worldwide\, with colorectal carcinoma (CRC) being the second-leading cause of tumour related-death. The high rate of mortality of CRCs is principally attributed to the metastasis of neoplastic cells from the primary tumour to secondary organs such as the liver\, the lung and the peritoneum. These cells can disseminate either as single isolated cells or as collective clusters\, undergoing a series of molecular and cellular changes commonly known as Epithelial to Mesenchymal Transition (EMT). However\, in 2018\, Jaulin and her team described a novel modality of peritoneal metastatic spread characterized by the presence of large clusters of cancer cells\, which maintain their epithelial properties and display an outward apical polarity. These clusters of cells\, termed tumour spheres with inverted polarity (TSIPs)\, were found in peritoneal effusions of CRCs patients showing early KRAS mutation and hypermethylation of CpG Islands. \nTSIPs originate through a series of morphological changes: the first event is the sprouting of hypermethylated epithelia\, followed by their apical budding\, leading to the formation of rounded spherical clusters of cells called buds\, and the subsequent cleavage of the newly formed spheres. How cell and tissue mechanics drive this process is still unclear. To provide novel insights into this metastatic cascade\, our project aims at deciphering the biomechanical and cellular events regulating the formation of buds in colorectal cancer cell lines. Employing a combination between cellular biology techniques with biophysical methods\, we showed that this process is characterized by over-proliferation and local changes in cell adhesion\, coupled with the formation of cellular vortexes surrounding the buds. Our study demonstrates that buds development in colorectal carcinomas epithelia is governed by morphological transitions occurring entirely at multicellular level\, rather than by single cells aggregation or cell extrusion. \nImaging Functional Organic Bioelectronic Platforms at the Nanoscale\nShubham Tanwar\, Nanoscale Bioelectrical Characterization group \nIn recent years\, many organic bioelectronic platforms have emerged to bridge the signaling gap between biology and technology. Organic bioelectronic platforms based on transistor architecture\, commonly known as Electrolyte-Gated Transistors (EGTs)\, are an excellent tool to selectively sense\, record\, and monitor biological signals and states\, and convert them into measurable electrical signals.1 Biological events happening at the nanoscale are now routinely studied and characterized by a millimeter-sized transistor. However\, it is not well understood how these nanoscale events interact with the transistor’s nanoscale properties leading to a change in their macroscale response. This gap in understanding is purely due to the lack of techniques to image the electrical properties in a liquid environment. Towards this goal\, our group has adapted in-Liquid Scanning Dielectric Microscopy to unravel the inner working of EGTs at the nanoscale.2 Besides apparent topographical changes\, electrical properties\, like conductivity and interfacial capacitance\, and mechanical properties are mapped at the nanoscale in a working transistor in liquid. The vast information extracted has made it possible to correlate the nanoscale processes with the macroscale response\, offering improved understanding and the potential for substantial optimization of bioelectronic devices. \nThis PhD Discussion session will be held at Tower I\, 11th floor Baobab room\, there will be 30 avialable seats\, the free spots will be assigned on a first come first served basis.
URL:https://ibecbarcelona.eu/event/phd-discussions-giulia-fornabaio-and-shubham-tanwar-2/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220225T100000
DTEND;TZID=Europe/Madrid:20220225T170000
DTSTAMP:20260404T004036
CREATED:20220427T110714Z
LAST-MODIFIED:20220503T142126Z
UID:93902-1645783200-1645808400@ibecbarcelona.eu
SUMMARY:PhD Discussions: Giulia Fornabaio and Shubham Tanwar
DESCRIPTION:Biomechanics of the progression of colorectal carcinomas\n\n\n\nGiulia Fornabaio\, Synthetic morphogenesis group \n\n\n\nAccording to the World Health Organization\, cancer is one of the main causes of death worldwide\, with colorectal carcinoma (CRC) being the second-leading cause of tumour related-death. The high rate of mortality of CRCs is principally attributed to the metastasis of neoplastic cells from the primary tumour to secondary organs such as the liver\, the lung and the peritoneum. These cells can disseminate either as single isolated cells or as collective clusters\, undergoing a series of molecular and cellular changes commonly known as Epithelial to Mesenchymal Transition (EMT). However\, in 2018\, Jaulin and her team described a novel modality of peritoneal metastatic spread characterized by the presence of large clusters of cancer cells\, which maintain their epithelial properties and display an outward apical polarity. These clusters of cells\, termed tumour spheres with inverted polarity (TSIPs)\, were found in peritoneal effusions of CRCs patients showing early KRAS mutation and hypermethylation of CpG Islands. \n\n\n\nTSIPs originate through a series of morphological changes: the first event is the sprouting of hypermethylated epithelia\, followed by their apical budding\, leading to the formation of rounded spherical clusters of cells called buds\, and the subsequent cleavage of the newly formed spheres. How cell and tissue mechanics drive this process is still unclear. To provide novel insights into this metastatic cascade\, our project aims at deciphering the biomechanical and cellular events regulating the formation of buds in colorectal cancer cell lines. Employing a combination between cellular biology techniques with biophysical methods\, we showed that this process is characterized by over-proliferation and local changes in cell adhesion\, coupled with the formation of cellular vortexes surrounding the buds. Our study demonstrates that buds development in colorectal carcinomas epithelia is governed by morphological transitions occurring entirely at multicellular level\, rather than by single cells aggregation or cell extrusion. \n\n\n\nImaging Functional Organic Bioelectronic Platforms at the Nanoscale\n\n\n\nShubham Tanwar\, Nanoscale Bioelectrical Characterization group \n\n\n\nIn recent years\, many organic bioelectronic platforms have emerged to bridge the signaling gap between biology and technology. Organic bioelectronic platforms based on transistor architecture\, commonly known as Electrolyte-Gated Transistors (EGTs)\, are an excellent tool to selectively sense\, record\, and monitor biological signals and states\, and convert them into measurable electrical signals.1 Biological events happening at the nanoscale are now routinely studied and characterized by a millimeter-sized transistor. However\, it is not well understood how these nanoscale events interact with the transistor’s nanoscale properties leading to a change in their macroscale response. This gap in understanding is purely due to the lack of techniques to image the electrical properties in a liquid environment. Towards this goal\, our group has adapted in-Liquid Scanning Dielectric Microscopy to unravel the inner working of EGTs at the nanoscale.2 Besides apparent topographical changes\, electrical properties\, like conductivity and interfacial capacitance\, and mechanical properties are mapped at the nanoscale in a working transistor in liquid. The vast information extracted has made it possible to correlate the nanoscale processes with the macroscale response\, offering improved understanding and the potential for substantial optimization of bioelectronic devices. \n\n\n\nThis PhD Discussion session will be held at Tower I\, 11th floor Baobab room\, there will be 30 avialable seats\, the free spots will be assigned on a first come first served basis.
URL:https://ibecbarcelona.eu/event/phd-discussions-giulia-fornabaio-and-shubham-tanwar/
LOCATION:IBEC\, floor 11\, Tower i\, Baldiri Reixac 4-8\, Barcelona\, 08028\, Spain
CATEGORIES:PhD Discussions Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220228T000000
DTEND;TZID=Europe/Madrid:20220228T130000
DTSTAMP:20260404T004036
CREATED:20220429T070900Z
LAST-MODIFIED:20220429T070901Z
UID:93910-1646006400-1646053200@ibecbarcelona.eu
SUMMARY:Nano Rare Diseases Day 2022
DESCRIPTION:Nano Rare Diseases Day es un evento organizado en el marco del Día Mundial de las Enfermedades Minoritarias donde se darán a conocer las últimas innovaciones en materia de Nanomedicina con temas que van desde el diagnóstico precoz\, la liberación controlada de fármacos o el desarrollo de nuevas terapias. \n\n\n\nDurante esta jornada\, expertos en Nanomedicina de diferentes campos -investigación\, empresa\, práctica clínica\, autoridades sanitarias\, pacientes\, etc.-\,  expondrán los últimos avances y nos darán la oportunidad de descubrir el generador de progreso que la Nanomedicina significa para la salud como creador de nuevas oportunidades en el diagnóstico y el tratamiento de las enfermedades minoritarias. \n\n\n\nRegistro a la jornada online\, aquí
URL:https://ibecbarcelona.eu/event/nano-rare-diseases-day-2022/
CATEGORIES:Joint seminar / workshop / symposium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220304T100000
DTEND;TZID=Europe/Madrid:20220304T120000
DTSTAMP:20260404T004036
CREATED:20220222T141809Z
LAST-MODIFIED:20220222T141809Z
UID:96534-1646388000-1646395200@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Stefano Pulchino
DESCRIPTION:Regenerative Neuroimmunology – new generation molecular approaches to restore maladaptive inflammatory responses in the persistently inflamed CNS\nStefano Pulchino\, University of Cambridge \nThere are currently no approved therapies to slow down the accumulation of neurological disability that occurs independently of relapses in multiple sclerosis (MS). International agencies are engaging to expedite the development of novel strategies capable of modifying disease progression\, abrogating persistent CNS inflammation\, and support degenerating axons in people with persistent inflammation of the\, such as that occurring in progressive MS. \nUnderstanding why regeneration fails in the progressive MS brain and developing new regenerative approaches is a key priority for the Pluchino Lab. \nIn particular\, we aim to elucidate how the immune system\, in particular its cells called myeloid cells\, affects brain structure and function under normal healthy conditions and in disease. \nOur objective is to find how myeloid cells communicate with the central nervous system and affect tissue healing and functional recovery by stimulating mechanisms of brain plasticity mechanisms such as the generation of new nerve cells and the reduction of scar formation. \nApplying combination of state-of-the-art omic technologies\, and molecular approaches to study murine and human disease models of inflammation and neurodegeneration\, we aim to develop experimental molecular medicines\, including those with stem cells and gene therapy vectors\, which slow down the accumulation of irreversible disabilities and improve functional recovery after progressive multiple sclerosis\, stroke and traumatic injuries. \nBy understanding the mechanisms of intercellular (neuro-immune) signalling\, diseases of the brain and spinal cord may be treated more effectively\, and significant neuroprotection may be achieved with new tailored molecular therapeutics. \n\nI have received my MD and PhD degrees at the University of Siena\, Italy\, and additional training at Cambridge University\, UK. I am currently Professor of Regenerative Neuroimmunology and Honorary Consultant in Neurology\, within the Department of Clinical Neurosciences at Cambridge University. \nI have a strong interest in Regenerative Neuroimmunology\, and my research over the last 20 years has recalibrated the classical view that cellular grafts only function through structural cell replacement and opened up a new therapeutic avenue by which to use exogenously delivered stem cells\, or even stem cell-derived acellular therapies that include extracellular vesicles and exosomes. \nThe Pluchino team studies whether the accumulation of neurological disability observed in patients with chronic inflammatory neurological conditions can be slowed down using next generation molecular therapies. The overarching aim is to understand the basic mechanisms that allow exogenously delivered stem cells\, gene therapy vectors and/or exosomes to create an environment that preserves damaged axons or prevents neurons from dying. Such mechanisms may be harnessed and used to modulate disease states in an effort to repair and/or regenerate critical components of the nervous system. \nI am recipient of numerous national and international awards\, among which the Italian Multiple Sclerosis Foundation (FISM) Rita Levi-Montalcini prize for outstanding research in MS (2007)\, the 2009 Italian Ministry of Health Young Investigator Award and the 2010 European Research Council (ERC) Starting Independent Award. \nMy laboratory research on Regenerative Neuroimmunology is documented in >230 publications in international journals\, including many recent articles in highly prestigious journals\, such as Nature\, Cell\, Cell Stem Cell\, Nat Cell Biol\, Nat Chem Biol\, PNAS\, PLoS Med\, Brain\, Ann Neurol\, and J Neurosci\, as well as invited review articles in Nat Rev Neurosci\, Physiol Reviews\, Trends in Mol Med and Trends Immunol. My publications have to date received >14.000 citations (ISI-WOK)\, having a Hirsch Factor of 52. \n\nThis seminar will take place online\, using the go to meeting app
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-stefano-pulchino-4/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220304T100000
DTEND;TZID=Europe/Madrid:20220304T120000
DTSTAMP:20260404T004036
CREATED:20220222T141809Z
LAST-MODIFIED:20220222T141809Z
UID:90595-1646388000-1646395200@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Stefano Pulchino
DESCRIPTION:Regenerative Neuroimmunology – new generation molecular approaches to restore maladaptive inflammatory responses in the persistently inflamed CNS\nStefano Pulchino\, University of Cambridge \nThere are currently no approved therapies to slow down the accumulation of neurological disability that occurs independently of relapses in multiple sclerosis (MS). International agencies are engaging to expedite the development of novel strategies capable of modifying disease progression\, abrogating persistent CNS inflammation\, and support degenerating axons in people with persistent inflammation of the\, such as that occurring in progressive MS. \nUnderstanding why regeneration fails in the progressive MS brain and developing new regenerative approaches is a key priority for the Pluchino Lab. \nIn particular\, we aim to elucidate how the immune system\, in particular its cells called myeloid cells\, affects brain structure and function under normal healthy conditions and in disease. \nOur objective is to find how myeloid cells communicate with the central nervous system and affect tissue healing and functional recovery by stimulating mechanisms of brain plasticity mechanisms such as the generation of new nerve cells and the reduction of scar formation. \nApplying combination of state-of-the-art omic technologies\, and molecular approaches to study murine and human disease models of inflammation and neurodegeneration\, we aim to develop experimental molecular medicines\, including those with stem cells and gene therapy vectors\, which slow down the accumulation of irreversible disabilities and improve functional recovery after progressive multiple sclerosis\, stroke and traumatic injuries. \nBy understanding the mechanisms of intercellular (neuro-immune) signalling\, diseases of the brain and spinal cord may be treated more effectively\, and significant neuroprotection may be achieved with new tailored molecular therapeutics. \n\nI have received my MD and PhD degrees at the University of Siena\, Italy\, and additional training at Cambridge University\, UK. I am currently Professor of Regenerative Neuroimmunology and Honorary Consultant in Neurology\, within the Department of Clinical Neurosciences at Cambridge University. \nI have a strong interest in Regenerative Neuroimmunology\, and my research over the last 20 years has recalibrated the classical view that cellular grafts only function through structural cell replacement and opened up a new therapeutic avenue by which to use exogenously delivered stem cells\, or even stem cell-derived acellular therapies that include extracellular vesicles and exosomes. \nThe Pluchino team studies whether the accumulation of neurological disability observed in patients with chronic inflammatory neurological conditions can be slowed down using next generation molecular therapies. The overarching aim is to understand the basic mechanisms that allow exogenously delivered stem cells\, gene therapy vectors and/or exosomes to create an environment that preserves damaged axons or prevents neurons from dying. Such mechanisms may be harnessed and used to modulate disease states in an effort to repair and/or regenerate critical components of the nervous system. \nI am recipient of numerous national and international awards\, among which the Italian Multiple Sclerosis Foundation (FISM) Rita Levi-Montalcini prize for outstanding research in MS (2007)\, the 2009 Italian Ministry of Health Young Investigator Award and the 2010 European Research Council (ERC) Starting Independent Award. \nMy laboratory research on Regenerative Neuroimmunology is documented in >230 publications in international journals\, including many recent articles in highly prestigious journals\, such as Nature\, Cell\, Cell Stem Cell\, Nat Cell Biol\, Nat Chem Biol\, PNAS\, PLoS Med\, Brain\, Ann Neurol\, and J Neurosci\, as well as invited review articles in Nat Rev Neurosci\, Physiol Reviews\, Trends in Mol Med and Trends Immunol. My publications have to date received >14.000 citations (ISI-WOK)\, having a Hirsch Factor of 52. \n\nThis seminar will take place online\, using the go to meeting app
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-stefano-pulchino-2/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220304T100000
DTEND;TZID=Europe/Madrid:20220304T120000
DTSTAMP:20260404T004036
CREATED:20220222T141809Z
LAST-MODIFIED:20220222T141809Z
UID:96531-1646388000-1646395200@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Stefano Pulchino
DESCRIPTION:Regenerative Neuroimmunology – new generation molecular approaches to restore maladaptive inflammatory responses in the persistently inflamed CNS\nStefano Pulchino\, University of Cambridge \nThere are currently no approved therapies to slow down the accumulation of neurological disability that occurs independently of relapses in multiple sclerosis (MS). International agencies are engaging to expedite the development of novel strategies capable of modifying disease progression\, abrogating persistent CNS inflammation\, and support degenerating axons in people with persistent inflammation of the\, such as that occurring in progressive MS. \nUnderstanding why regeneration fails in the progressive MS brain and developing new regenerative approaches is a key priority for the Pluchino Lab. \nIn particular\, we aim to elucidate how the immune system\, in particular its cells called myeloid cells\, affects brain structure and function under normal healthy conditions and in disease. \nOur objective is to find how myeloid cells communicate with the central nervous system and affect tissue healing and functional recovery by stimulating mechanisms of brain plasticity mechanisms such as the generation of new nerve cells and the reduction of scar formation. \nApplying combination of state-of-the-art omic technologies\, and molecular approaches to study murine and human disease models of inflammation and neurodegeneration\, we aim to develop experimental molecular medicines\, including those with stem cells and gene therapy vectors\, which slow down the accumulation of irreversible disabilities and improve functional recovery after progressive multiple sclerosis\, stroke and traumatic injuries. \nBy understanding the mechanisms of intercellular (neuro-immune) signalling\, diseases of the brain and spinal cord may be treated more effectively\, and significant neuroprotection may be achieved with new tailored molecular therapeutics. \n\nI have received my MD and PhD degrees at the University of Siena\, Italy\, and additional training at Cambridge University\, UK. I am currently Professor of Regenerative Neuroimmunology and Honorary Consultant in Neurology\, within the Department of Clinical Neurosciences at Cambridge University. \nI have a strong interest in Regenerative Neuroimmunology\, and my research over the last 20 years has recalibrated the classical view that cellular grafts only function through structural cell replacement and opened up a new therapeutic avenue by which to use exogenously delivered stem cells\, or even stem cell-derived acellular therapies that include extracellular vesicles and exosomes. \nThe Pluchino team studies whether the accumulation of neurological disability observed in patients with chronic inflammatory neurological conditions can be slowed down using next generation molecular therapies. The overarching aim is to understand the basic mechanisms that allow exogenously delivered stem cells\, gene therapy vectors and/or exosomes to create an environment that preserves damaged axons or prevents neurons from dying. Such mechanisms may be harnessed and used to modulate disease states in an effort to repair and/or regenerate critical components of the nervous system. \nI am recipient of numerous national and international awards\, among which the Italian Multiple Sclerosis Foundation (FISM) Rita Levi-Montalcini prize for outstanding research in MS (2007)\, the 2009 Italian Ministry of Health Young Investigator Award and the 2010 European Research Council (ERC) Starting Independent Award. \nMy laboratory research on Regenerative Neuroimmunology is documented in >230 publications in international journals\, including many recent articles in highly prestigious journals\, such as Nature\, Cell\, Cell Stem Cell\, Nat Cell Biol\, Nat Chem Biol\, PNAS\, PLoS Med\, Brain\, Ann Neurol\, and J Neurosci\, as well as invited review articles in Nat Rev Neurosci\, Physiol Reviews\, Trends in Mol Med and Trends Immunol. My publications have to date received >14.000 citations (ISI-WOK)\, having a Hirsch Factor of 52. \n\nThis seminar will take place online\, using the go to meeting app
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-stefano-pulchino-3/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220304T100000
DTEND;TZID=Europe/Madrid:20220304T120000
DTSTAMP:20260404T004036
CREATED:20220429T090715Z
LAST-MODIFIED:20220429T090716Z
UID:93913-1646388000-1646395200@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Stefano Pulchino
DESCRIPTION:Regenerative Neuroimmunology – new generation molecular approaches to restore maladaptive inflammatory responses in the persistently inflamed CNS\n\n\n\nStefano Pulchino\, University of Cambridge \n\n\n\nThere are currently no approved therapies to slow down the accumulation of neurological disability that occurs independently of relapses in multiple sclerosis (MS). International agencies are engaging to expedite the development of novel strategies capable of modifying disease progression\, abrogating persistent CNS inflammation\, and support degenerating axons in people with persistent inflammation of the\, such as that occurring in progressive MS. \n\n\n\nUnderstanding why regeneration fails in the progressive MS brain and developing new regenerative approaches is a key priority for the Pluchino Lab. \n\n\n\nIn particular\, we aim to elucidate how the immune system\, in particular its cells called myeloid cells\, affects brain structure and function under normal healthy conditions and in disease. \n\n\n\nOur objective is to find how myeloid cells communicate with the central nervous system and affect tissue healing and functional recovery by stimulating mechanisms of brain plasticity mechanisms such as the generation of new nerve cells and the reduction of scar formation. \n\n\n\nApplying combination of state-of-the-art omic technologies\, and molecular approaches to study murine and human disease models of inflammation and neurodegeneration\, we aim to develop experimental molecular medicines\, including those with stem cells and gene therapy vectors\, which slow down the accumulation of irreversible disabilities and improve functional recovery after progressive multiple sclerosis\, stroke and traumatic injuries. \n\n\n\nBy understanding the mechanisms of intercellular (neuro-immune) signalling\, diseases of the brain and spinal cord may be treated more effectively\, and significant neuroprotection may be achieved with new tailored molecular therapeutics. \n\n\n\n\n\n\n\nI have received my MD and PhD degrees at the University of Siena\, Italy\, and additional training at Cambridge University\, UK. I am currently Professor of Regenerative Neuroimmunology and Honorary Consultant in Neurology\, within the Department of Clinical Neurosciences at Cambridge University. \n\n\n\nI have a strong interest in Regenerative Neuroimmunology\, and my research over the last 20 years has recalibrated the classical view that cellular grafts only function through structural cell replacement and opened up a new therapeutic avenue by which to use exogenously delivered stem cells\, or even stem cell-derived acellular therapies that include extracellular vesicles and exosomes. \n\n\n\nThe Pluchino team studies whether the accumulation of neurological disability observed in patients with chronic inflammatory neurological conditions can be slowed down using next generation molecular therapies. The overarching aim is to understand the basic mechanisms that allow exogenously delivered stem cells\, gene therapy vectors and/or exosomes to create an environment that preserves damaged axons or prevents neurons from dying. Such mechanisms may be harnessed and used to modulate disease states in an effort to repair and/or regenerate critical components of the nervous system. \n\n\n\nI am recipient of numerous national and international awards\, among which the Italian Multiple Sclerosis Foundation (FISM) Rita Levi-Montalcini prize for outstanding research in MS (2007)\, the 2009 Italian Ministry of Health Young Investigator Award and the 2010 European Research Council (ERC) Starting Independent Award. \n\n\n\nMy laboratory research on Regenerative Neuroimmunology is documented in >230 publications in international journals\, including many recent articles in highly prestigious journals\, such as Nature\, Cell\, Cell Stem Cell\, Nat Cell Biol\, Nat Chem Biol\, PNAS\, PLoS Med\, Brain\, Ann Neurol\, and J Neurosci\, as well as invited review articles in Nat Rev Neurosci\, Physiol Reviews\, Trends in Mol Med and Trends Immunol. My publications have to date received >14.000 citations (ISI-WOK)\, having a Hirsch Factor of 52. \n\n\n\n\n\n\n\nThis seminar will take place online\, using the go to meeting app
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-stefano-pulchino/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220314T110000
DTEND;TZID=Europe/Madrid:20220314T130000
DTSTAMP:20260404T004036
CREATED:20220309T120100Z
LAST-MODIFIED:20220309T120100Z
UID:96542-1647255600-1647262800@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Andrés Marco Giménez
DESCRIPTION:Generation and Validation of a CRISPR Platform for Rapid and Inducible Genome Editing in Human Pluripotent Stem Cells and Kidney Organoids\nAndrés Marco Giménez\, Pluripotency for organ regeneration group \nThis thesis defence will start at 11AM. If you wisth to attend to this PhD thesis defence\, you can join here via zoom.
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-andres-marco-gimenez-3/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220314T110000
DTEND;TZID=Europe/Madrid:20220314T130000
DTSTAMP:20260404T004036
CREATED:20220309T120100Z
LAST-MODIFIED:20220309T120100Z
UID:90898-1647255600-1647262800@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Andrés Marco Giménez
DESCRIPTION:Generation and Validation of a CRISPR Platform for Rapid and Inducible Genome Editing in Human Pluripotent Stem Cells and Kidney Organoids\nAndrés Marco Giménez\, Pluripotency for organ regeneration group \nThis thesis defence will start at 11AM. If you wisth to attend to this PhD thesis defence\, you can join here via zoom.
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-andres-marco-gimenez-4/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220314T110000
DTEND;TZID=Europe/Madrid:20220314T130000
DTSTAMP:20260404T004036
CREATED:20220309T120100Z
LAST-MODIFIED:20220309T120100Z
UID:96540-1647255600-1647262800@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Andrés Marco Giménez
DESCRIPTION:Generation and Validation of a CRISPR Platform for Rapid and Inducible Genome Editing in Human Pluripotent Stem Cells and Kidney Organoids\nAndrés Marco Giménez\, Pluripotency for organ regeneration group \nThis thesis defence will start at 11AM. If you wisth to attend to this PhD thesis defence\, you can join here via zoom.
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-andres-marco-gimenez-2/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220314T110000
DTEND;TZID=Europe/Madrid:20220314T130000
DTSTAMP:20260404T004036
CREATED:20220503T133307Z
LAST-MODIFIED:20220503T133308Z
UID:93986-1647255600-1647262800@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Andrés Marco Giménez
DESCRIPTION:Generation and Validation of a CRISPR Platform for Rapid and Inducible Genome Editing in Human Pluripotent Stem Cells and Kidney Organoids\n\n\n\nAndrés Marco Giménez\, Pluripotency for organ regeneration group \n\n\n\nThis thesis defence will start at 11AM. If you wisth to attend to this PhD thesis defence\, you can join here via zoom.
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-andres-marco-gimenez/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220314T160000
DTEND;TZID=Europe/Madrid:20220314T170000
DTSTAMP:20260404T004036
CREATED:20220309T092904Z
LAST-MODIFIED:20220309T092904Z
UID:90888-1647273600-1647277200@ibecbarcelona.eu
SUMMARY:IBEC Seminar: André Körnig
DESCRIPTION:NanoWizard® V BioScience – The latest Generation AFM for Automated Structural and Mechanical Analysis & NanoRacer® – High-Speed AFM for dynamical processes\nAndré Körnig\, JPK BioAFM\, Bruker Nano GmbH \nThe ability of atomic force microscopy (AFM) to obtain three-dimensional topography images of biological molecules and complexes with nanometer resolution and under near-physiological conditions remains unmatched by other imaging techniques. Bruker BioAFM has recently launched the NanoWizard® V BioScience AFM that combines high spatio-temporal resolution with a large scan area\, flexible experiment design\, and outstanding integration with advanced optical microscope systems. \nThis talk will focus on how the advances in Bruker’s latest BioAFM can be applied to study a wide-range of biological samples: from individual biomolecules to mammalian cells and tissues in-situ. It will be presented how we are able to resolve the nanoscale structure of individual biomolecules\, at high-speed scan rates (400 lines/sec)\, follow the dynamic reorganization of the membrane-associated cytoskeleton of living cells at high temporal and spatial resolution. It will be highlighted\, how the topography of cells across the entire area of the microscope stage can be automatically mapped. Special part will be dedicated to the suite of BioAFM modes\, probes and accessories for studying nanomechanical properties of cells and tissues\, including direct correlation with super-resolution microscopy techniques (STED). \nIn the past\, investigating large and rough samples such as tissues and hydrogels using AFM was challenging due to the limited z-axis of the AFM. Using osteoarthritic cartilage as an example\, we will demonstrate how a newly developed hybrid of a motorized and piezo stage enables multi-region AFM probing over a large\, rough sample area while providing additional correlative optical data sets. \nThe newly developed NanoRacer® High-Speed AFM enables scanning speeds of up to 50 frames per second. In this way\, the high-speed study of the time-resolved dynamics associated with cellular processes and the binding mechanisms of individual biomolecules is possible\, e.g. the dynamics of single molecule binding behavior\, two-dimensional protein assemblies\, motor proteins and membrane trafficking. \nWe will present data on DNA origami nanostructures containing biotin binding sites\, imaged in fluid in the presence of streptavidin\, as well as data on DNA metastable bubble formation and closure (~30 nm in length)\, imaged in fluid in closed-loop at 2000 lines per second. \n\nThis seminar will be held at Tower I\, 11th floor Baobab room\, there will be 30 avialable seats\, the free spots will be assigned on a first come first served basis.
URL:https://ibecbarcelona.eu/event/ibec-seminar-andre-kornig-2/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:IBEC Seminar
ORGANIZER;CN="IBEC":MAILTO:www.ibecbarcelona.eu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220314T160000
DTEND;TZID=Europe/Madrid:20220314T170000
DTSTAMP:20260404T004036
CREATED:20220309T092904Z
LAST-MODIFIED:20220309T092904Z
UID:90890-1647273600-1647277200@ibecbarcelona.eu
SUMMARY:IBEC Seminar: André Körnig
DESCRIPTION:NanoWizard® V BioScience – The latest Generation AFM for Automated Structural and Mechanical Analysis & NanoRacer® – High-Speed AFM for dynamical processes\nAndré Körnig\, JPK BioAFM\, Bruker Nano GmbH \nThe ability of atomic force microscopy (AFM) to obtain three-dimensional topography images of biological molecules and complexes with nanometer resolution and under near-physiological conditions remains unmatched by other imaging techniques. Bruker BioAFM has recently launched the NanoWizard® V BioScience AFM that combines high spatio-temporal resolution with a large scan area\, flexible experiment design\, and outstanding integration with advanced optical microscope systems. \n  \nThis talk will focus on how the advances in Bruker’s latest BioAFM can be applied to study a wide-range of biological samples: from individual biomolecules to mammalian cells and tissues in-situ. It will be presented how we are able to resolve the nanoscale structure of individual biomolecules\, at high-speed scan rates (400 lines/sec)\, follow the dynamic reorganization of the membrane-associated cytoskeleton of living cells at high temporal and spatial resolution. It will be highlighted\, how the topography of cells across the entire area of the microscope stage can be automatically mapped. Special part will be dedicated to the suite of BioAFM modes\, probes and accessories for studying nanomechanical properties of cells and tissues\, including direct correlation with super-resolution microscopy techniques (STED). \nIn the past\, investigating large and rough samples such as tissues and hydrogels using AFM was challenging due to the limited z-axis of the AFM. Using osteoarthritic cartilage as an example\, we will demonstrate how a newly developed hybrid of a motorized and piezo stage enables multi-region AFM probing over a large\, rough sample area while providing additional correlative optical data sets. \nThe newly developed NanoRacer® High-Speed AFM enables scanning speeds of up to 50 frames per second. In this way\, the high-speed study of the time-resolved dynamics associated with cellular processes and the binding mechanisms of individual biomolecules is possible\, e.g. the dynamics of single molecule binding behavior\, two-dimensional protein assemblies\, motor proteins and membrane trafficking. \nWe will present data on DNA origami nanostructures containing biotin binding sites\, imaged in fluid in the presence of streptavidin\, as well as data on DNA metastable bubble formation and closure (~30 nm in length)\, imaged in fluid in closed-loop at 2000 lines per second. \n\nThis seminar will be held at Tower I\, 11th floor Baobab room\, there will be 30 avialable seats\, the free spots will be assigned on a first come first served basis.
URL:https://ibecbarcelona.eu/event/ibec-seminar-andre-kornig-4/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:IBEC Seminar
ORGANIZER;CN="IBEC":MAILTO:www.ibecbarcelona.eu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220314T160000
DTEND;TZID=Europe/Madrid:20220314T170000
DTSTAMP:20260404T004036
CREATED:20220309T092904Z
LAST-MODIFIED:20220309T092904Z
UID:96537-1647273600-1647277200@ibecbarcelona.eu
SUMMARY:IBEC Seminar: André Körnig
DESCRIPTION:NanoWizard® V BioScience – The latest Generation AFM for Automated Structural and Mechanical Analysis & NanoRacer® – High-Speed AFM for dynamical processes\nAndré Körnig\, JPK BioAFM\, Bruker Nano GmbH \nThe ability of atomic force microscopy (AFM) to obtain three-dimensional topography images of biological molecules and complexes with nanometer resolution and under near-physiological conditions remains unmatched by other imaging techniques. Bruker BioAFM has recently launched the NanoWizard® V BioScience AFM that combines high spatio-temporal resolution with a large scan area\, flexible experiment design\, and outstanding integration with advanced optical microscope systems. \n  \nThis talk will focus on how the advances in Bruker’s latest BioAFM can be applied to study a wide-range of biological samples: from individual biomolecules to mammalian cells and tissues in-situ. It will be presented how we are able to resolve the nanoscale structure of individual biomolecules\, at high-speed scan rates (400 lines/sec)\, follow the dynamic reorganization of the membrane-associated cytoskeleton of living cells at high temporal and spatial resolution. It will be highlighted\, how the topography of cells across the entire area of the microscope stage can be automatically mapped. Special part will be dedicated to the suite of BioAFM modes\, probes and accessories for studying nanomechanical properties of cells and tissues\, including direct correlation with super-resolution microscopy techniques (STED). \nIn the past\, investigating large and rough samples such as tissues and hydrogels using AFM was challenging due to the limited z-axis of the AFM. Using osteoarthritic cartilage as an example\, we will demonstrate how a newly developed hybrid of a motorized and piezo stage enables multi-region AFM probing over a large\, rough sample area while providing additional correlative optical data sets. \nThe newly developed NanoRacer® High-Speed AFM enables scanning speeds of up to 50 frames per second. In this way\, the high-speed study of the time-resolved dynamics associated with cellular processes and the binding mechanisms of individual biomolecules is possible\, e.g. the dynamics of single molecule binding behavior\, two-dimensional protein assemblies\, motor proteins and membrane trafficking. \nWe will present data on DNA origami nanostructures containing biotin binding sites\, imaged in fluid in the presence of streptavidin\, as well as data on DNA metastable bubble formation and closure (~30 nm in length)\, imaged in fluid in closed-loop at 2000 lines per second. \n\nThis seminar will be held at Tower I\, 11th floor Baobab room\, there will be 30 avialable seats\, the free spots will be assigned on a first come first served basis.
URL:https://ibecbarcelona.eu/event/ibec-seminar-andre-kornig-3/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:IBEC Seminar
ORGANIZER;CN="IBEC":MAILTO:www.ibecbarcelona.eu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220314T160000
DTEND;TZID=Europe/Madrid:20220314T170000
DTSTAMP:20260404T004036
CREATED:20220503T134023Z
LAST-MODIFIED:20220503T134024Z
UID:93989-1647273600-1647277200@ibecbarcelona.eu
SUMMARY:IBEC Seminar: André Körnig
DESCRIPTION:NanoWizard® V BioScience – The latest Generation AFM for Automated Structural and Mechanical Analysis & NanoRacer® – High-Speed AFM for dynamical processes\n\n\n\nAndré Körnig\, JPK BioAFM\, Bruker Nano GmbH \n\n\n\nThe ability of atomic force microscopy (AFM) to obtain three-dimensional topography images of biological molecules and complexes with nanometer resolution and under near-physiological conditions remains unmatched by other imaging techniques. Bruker BioAFM has recently launched the NanoWizard® V BioScience AFM that combines high spatio-temporal resolution with a large scan area\, flexible experiment design\, and outstanding integration with advanced optical microscope systems. \n\n\n\nThis talk will focus on how the advances in Bruker’s latest BioAFM can be applied to study a wide-range of biological samples: from individual biomolecules to mammalian cells and tissues in-situ. It will be presented how we are able to resolve the nanoscale structure of individual biomolecules\, at high-speed scan rates (400 lines/sec)\, follow the dynamic reorganization of the membrane-associated cytoskeleton of living cells at high temporal and spatial resolution. It will be highlighted\, how the topography of cells across the entire area of the microscope stage can be automatically mapped. Special part will be dedicated to the suite of BioAFM modes\, probes and accessories for studying nanomechanical properties of cells and tissues\, including direct correlation with super-resolution microscopy techniques (STED). \n\n\n\nIn the past\, investigating large and rough samples such as tissues and hydrogels using AFM was challenging due to the limited z-axis of the AFM. Using osteoarthritic cartilage as an example\, we will demonstrate how a newly developed hybrid of a motorized and piezo stage enables multi-region AFM probing over a large\, rough sample area while providing additional correlative optical data sets. \n\n\n\nThe newly developed NanoRacer® High-Speed AFM enables scanning speeds of up to 50 frames per second. In this way\, the high-speed study of the time-resolved dynamics associated with cellular processes and the binding mechanisms of individual biomolecules is possible\, e.g. the dynamics of single molecule binding behavior\, two-dimensional protein assemblies\, motor proteins and membrane trafficking. \n\n\n\nWe will present data on DNA origami nanostructures containing biotin binding sites\, imaged in fluid in the presence of streptavidin\, as well as data on DNA metastable bubble formation and closure (~30 nm in length)\, imaged in fluid in closed-loop at 2000 lines per second. \n\n\n\n\n\n\n\nThis seminar will be held at Tower I\, 11th floor Baobab room\, there will be 30 avialable seats\, the free spots will be assigned on a first come first served basis.
URL:https://ibecbarcelona.eu/event/ibec-seminar-andre-kornig/
LOCATION:IBEC\, floor 11\, Tower i
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220318T100000
DTEND;TZID=Europe/Madrid:20220318T120000
DTSTAMP:20260404T004036
CREATED:20210901T150406Z
LAST-MODIFIED:20220112T144731Z
UID:86918-1647597600-1647604800@ibecbarcelona.eu
SUMMARY:PhD Complementary Skills Session: Fernando T. Maestre
DESCRIPTION:Fernando T. Maestre\, Dryland Ecology and Global Change Lab at Universidad de Alicante. \nThis seminar will be held using the GoToMeeting app
URL:https://ibecbarcelona.eu/event/phd-complementary-skills-session-fernando-t-maestre/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220318T100000
DTEND;TZID=Europe/Madrid:20220318T120000
DTSTAMP:20260404T004036
CREATED:20220503T134531Z
LAST-MODIFIED:20220503T134532Z
UID:93992-1647597600-1647604800@ibecbarcelona.eu
SUMMARY:PhD Complementary Skills Session: Alicia Calvo-Villamañán
DESCRIPTION:Making your science accessible with illustrations and humour\n\n\n\nAlicia Calvo-Villamañán\, CNB – CSIC. \n\n\n\nAs researchers we are accustomed to sharing our science mostly with people that have similar sets of skills to ours. But what happens when we have to share our science with people whose backgrounds are radically different to what we’re used to? In these cases\, we enter the domain of science communication and science outreach\, a radically different way of communicating science that requires equally radically different skills of communication. \n\n\n\nScientific illustration is a great way to make one’s science more accessible to the general public\, as it helps others visualise complex scientific concepts that would be totally foreign to them otherwise. Being able to convert what we do every day in the lab into approachable illustrations takes a bit of imagination\, a lot of trial and error\, and why not\, a bit of humour as well. \n\n\n\nFrom very simple stick figures to more complex illustrations\, from digital art to more classical media\, helping others visualise your work will help you keep your audience more engaged with your work\, as well as help them understand it better. \n\n\n\n\n\n\n\nAlicia a postdoc in the lab of Dr. Álvaro San Millán. Her current research focuses on the understanding of sucessful plasmid-bacteria associations in nosocomimal infections to try to prevent the further dissemination of antimicrobial resistance in hospitals. \n\n\n\nPast research topics have included the study of CRISPR-Cas systems and the development of synthetic biology tools to tackle the challenge of antimicrobial resistance. \n\n\n\n“I am a sleepy\, caffeinated molecular biologist by day and a hyper scientific illustrator by night. You can learn more about my science outreach and scientific illustration work in this website.” \n\n\n\nYou can check here her publications \n\n\n\nThis seminar will be held at Tower I\, 11th floor Baobab room\, there will be 30 avialable seats\, the free spots will be assigned on a first come first served basis.
URL:https://ibecbarcelona.eu/event/phd-complementary-skills-session-alicia-calvo-villamanan/
LOCATION:IBEC\, floor 11\, Tower i
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220323T140000
DTEND;TZID=Europe/Madrid:20220323T170000
DTSTAMP:20260404T004036
CREATED:20220310T162449Z
LAST-MODIFIED:20220310T162449Z
UID:96553-1648044000-1648054800@ibecbarcelona.eu
SUMMARY:ICMS-IBEC Joint Online Symposium
DESCRIPTION:This is the 6th symposium that the two institutions are celebrating together. This Mini-Symposium will take place online\, using the Teams app\, on 23 March from 14.00 – 17.00. \n  \n\n\n\n \nSpeaker\nTitle\n\n\n14.00\nChair: Jan van Hest (ICMS)  \nSamuel Sánchez (IBEC)\nOpening and welcome\n\n\n \nSuccessful joint ventures\n\n\n\n14.05\nShidong Song and Richard Post (IBEC & ICMS) \nPartnership between: \nGroup lead IBEC: Samuel Sánchez \nGroup lead ICMS: Remco van der Hofstad and Jan van Hest\nEngineering transient dynamics of artificial cells by stochastic distribution of enzymes\n\n\n14.30\nSertan Sukas (IBEC & ICMS) \nPartnership between: \nGroup lead IBEC: Josep Samitier (IBEC) \nGroup lead ICMS: Vito Conte\, Jaap den Toonder and Regina Luttge\nAdvanced flow control and quantification of forces for mechanobiology studies\n\n\n14.55\nTania Patiño Padial (IBEC→ICMS) \nTania was a member of the group of Samuel Sánchez at IBEC and is now a member of the group of Jan van Hest at ICMS\nBioengineering life-like nanosystems for biomedical applications\n\n\n15.20\nBreak\n\n\n\n \nFlash talks Exchange program\n\n\n\n15.30\nRobert Dassen (ICMS→IBEC) \nPartnership between: \nGroup leads IBEC: Veronika Magdanz and Samuel Sánchez \nGroup lead ICMS: Hans Wyss\n3D printing of organ models for in vitro testing of microrobots\n\n\n15.38\nLisa van Slagmaat (ICMS→IBEC) \nPartnership between: \nGroup lead IBEC: Josep Samitier \nGroup lead ICMS: Jaap den Toonder\nMicrofluidic herringbone device with self-assembled antibody monolayer for CTC separation\n\n\n15.46\nFloor Ummels (ICMS→IBEC) \nPartnership between: \nGroup lead IBEC: Giuseppe Battaglia \nGroup lead ICMS: Willem Mulder\nCrossing the blood-brain barrier\n\n\n15.54\nLisa Pomp (ICMS→IBEC) \nPartnership between: \nGroup leads IBEC: José Antonio Del Río and Karen Wells \nGroup lead ICMS: Vito Conte\nEstablishment of an in vitro blood-brain barrier model on transwells for transendothelial transport studies\n\n\n16.04\nStan van Wetten (ICMS→IBEC) \nPartnership between: \nGroup lead IBEC: Sílvia Pujals \nGroup lead ICMS: Arthur de Jong\nCorrelating Light and Electron Microscopy for PLGA-PEG nanoparticle charactization\n\n\n16.12\nLaura van de Koppel (ICMS→IBEC) \nPartnership between: \nGroup leads IBEC: Elisabeth Engel and Bárbara Blanco \nGroup lead ICMS: Patricia Dankers\nEngineering a 3D model of lymphoma using a hydrogel for precise screening of therapeutics\n\n\n16.20\nBreak \n\n\n\n16.35\nRoger Riera Brillas (IBEC & ICMS) \nRoger was a member of the  group of Lorenzo Albertazzi at IBEC and is now a member of the group of Lorenzo Albertazzi at ICMS\n Live-cell uPAINT imaging of receptors\n\n\n17.00\nClosing remarks
URL:https://ibecbarcelona.eu/event/icms-ibec-joint-online-symposium-2/
CATEGORIES:Joint seminar / workshop / symposium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220323T140000
DTEND;TZID=Europe/Madrid:20220323T170000
DTSTAMP:20260404T004036
CREATED:20220310T162449Z
LAST-MODIFIED:20220310T162449Z
UID:96555-1648044000-1648054800@ibecbarcelona.eu
SUMMARY:ICMS-IBEC Joint Online Symposium
DESCRIPTION:This is the 6th symposium that the two institutions are celebrating together. This Mini-Symposium will take place online\, using the Teams app\, on 23 March from 14.00 – 17.00. \n  \n\n\n\n \nSpeaker\nTitle\n\n\n14.00\nChair: Jan van Hest (ICMS)  \nSamuel Sánchez (IBEC)\nOpening and welcome\n\n\n \nSuccessful joint ventures\n\n\n\n14.05\nShidong Song and Richard Post (IBEC & ICMS) \nPartnership between: \nGroup lead IBEC: Samuel Sánchez \nGroup lead ICMS: Remco van der Hofstad and Jan van Hest\nEngineering transient dynamics of artificial cells by stochastic distribution of enzymes\n\n\n14.30\nSertan Sukas (IBEC & ICMS) \nPartnership between: \nGroup lead IBEC: Josep Samitier (IBEC) \nGroup lead ICMS: Vito Conte\, Jaap den Toonder and Regina Luttge\nAdvanced flow control and quantification of forces for mechanobiology studies\n\n\n14.55\nTania Patiño Padial (IBEC→ICMS) \nTania was a member of the group of Samuel Sánchez at IBEC and is now a member of the group of Jan van Hest at ICMS\nBioengineering life-like nanosystems for biomedical applications\n\n\n15.20\nBreak\n\n\n\n \nFlash talks Exchange program\n\n\n\n15.30\nRobert Dassen (ICMS→IBEC) \nPartnership between: \nGroup leads IBEC: Veronika Magdanz and Samuel Sánchez \nGroup lead ICMS: Hans Wyss\n3D printing of organ models for in vitro testing of microrobots\n\n\n15.38\nLisa van Slagmaat (ICMS→IBEC) \nPartnership between: \nGroup lead IBEC: Josep Samitier \nGroup lead ICMS: Jaap den Toonder\nMicrofluidic herringbone device with self-assembled antibody monolayer for CTC separation\n\n\n15.46\nFloor Ummels (ICMS→IBEC) \nPartnership between: \nGroup lead IBEC: Giuseppe Battaglia \nGroup lead ICMS: Willem Mulder\nCrossing the blood-brain barrier\n\n\n15.54\nLisa Pomp (ICMS→IBEC) \nPartnership between: \nGroup leads IBEC: José Antonio Del Río and Karen Wells \nGroup lead ICMS: Vito Conte\nEstablishment of an in vitro blood-brain barrier model on transwells for transendothelial transport studies\n\n\n16.04\nStan van Wetten (ICMS→IBEC) \nPartnership between: \nGroup lead IBEC: Sílvia Pujals \nGroup lead ICMS: Arthur de Jong\nCorrelating Light and Electron Microscopy for PLGA-PEG nanoparticle charactization\n\n\n16.12\nLaura van de Koppel (ICMS→IBEC) \nPartnership between: \nGroup leads IBEC: Elisabeth Engel and Bárbara Blanco \nGroup lead ICMS: Patricia Dankers\nEngineering a 3D model of lymphoma using a hydrogel for precise screening of therapeutics\n\n\n16.20\nBreak \n\n\n\n16.35\nRoger Riera Brillas (IBEC & ICMS) \nRoger was a member of the  group of Lorenzo Albertazzi at IBEC and is now a member of the group of Lorenzo Albertazzi at ICMS\n Live-cell uPAINT imaging of receptors\n\n\n17.00\nClosing remarks
URL:https://ibecbarcelona.eu/event/icms-ibec-joint-online-symposium-3/
CATEGORIES:Joint seminar / workshop / symposium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220323T140000
DTEND;TZID=Europe/Madrid:20220323T170000
DTSTAMP:20260404T004036
CREATED:20220310T162449Z
LAST-MODIFIED:20220310T162449Z
UID:90903-1648044000-1648054800@ibecbarcelona.eu
SUMMARY:ICMS-IBEC Joint Online Symposium
DESCRIPTION:This is the 6th symposium that the two institutions are celebrating together. This Mini-Symposium will take place online\, using the Teams app\, on 23 March from 14.00 – 17.00. \n  \n\n\n\n \nSpeaker\nTitle\n\n\n14.00\nChair: Jan van Hest (ICMS)  \nSamuel Sánchez (IBEC)\nOpening and welcome\n\n\n \nSuccessful joint ventures\n\n\n\n14.05\nShidong Song and Richard Post (IBEC & ICMS) \nPartnership between: \nGroup lead IBEC: Samuel Sánchez \nGroup lead ICMS: Remco van der Hofstad and Jan van Hest\nEngineering transient dynamics of artificial cells by stochastic distribution of enzymes\n\n\n14.30\nSertan Sukas (IBEC & ICMS) \nPartnership between: \nGroup lead IBEC: Josep Samitier (IBEC) \nGroup lead ICMS: Vito Conte\, Jaap den Toonder and Regina Luttge\nAdvanced flow control and quantification of forces for mechanobiology studies\n\n\n14.55\nTania Patiño Padial (IBEC→ICMS) \nTania was a member of the group of Samuel Sánchez at IBEC and is now a member of the group of Jan van Hest at ICMS\nBioengineering life-like nanosystems for biomedical applications\n\n\n15.20\nBreak\n\n\n\n \nFlash talks Exchange program\n\n\n\n15.30\nRobert Dassen (ICMS→IBEC) \nPartnership between: \nGroup leads IBEC: Veronika Magdanz and Samuel Sánchez \nGroup lead ICMS: Hans Wyss\n3D printing of organ models for in vitro testing of microrobots\n\n\n15.38\nLisa van Slagmaat (ICMS→IBEC) \nPartnership between: \nGroup lead IBEC: Josep Samitier \nGroup lead ICMS: Jaap den Toonder\nMicrofluidic herringbone device with self-assembled antibody monolayer for CTC separation\n\n\n15.46\nFloor Ummels (ICMS→IBEC) \nPartnership between: \nGroup lead IBEC: Giuseppe Battaglia \nGroup lead ICMS: Willem Mulder\nCrossing the blood-brain barrier\n\n\n15.54\nLisa Pomp (ICMS→IBEC) \nPartnership between: \nGroup leads IBEC: José Antonio Del Río and Karen Wells \nGroup lead ICMS: Vito Conte\nEstablishment of an in vitro blood-brain barrier model on transwells for transendothelial transport studies\n\n\n16.04\nStan van Wetten (ICMS→IBEC) \nPartnership between: \nGroup lead IBEC: Sílvia Pujals \nGroup lead ICMS: Arthur de Jong\nCorrelating Light and Electron Microscopy for PLGA-PEG nanoparticle charactization\n\n\n16.12\nLaura van de Koppel (ICMS→IBEC) \nPartnership between: \nGroup leads IBEC: Elisabeth Engel and Bárbara Blanco \nGroup lead ICMS: Patricia Dankers\nEngineering a 3D model of lymphoma using a hydrogel for precise screening of therapeutics\n\n\n16.20\nBreak \n\n\n\n16.35\nRoger Riera Brillas (IBEC & ICMS) \nRoger was a member of the  group of Lorenzo Albertazzi at IBEC and is now a member of the group of Lorenzo Albertazzi at ICMS\n Live-cell uPAINT imaging of receptors\n\n\n17.00\nClosing remarks
URL:https://ibecbarcelona.eu/event/icms-ibec-joint-online-symposium-2/
CATEGORIES:Joint seminar / workshop / symposium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220323T140000
DTEND;TZID=Europe/Madrid:20220323T170000
DTSTAMP:20260404T004036
CREATED:20220503T134916Z
LAST-MODIFIED:20220503T134917Z
UID:93995-1648044000-1648054800@ibecbarcelona.eu
SUMMARY:ICMS-IBEC Joint Online Symposium
DESCRIPTION:This is the 6th symposium that the two institutions are celebrating together. This Mini-Symposium will take place online\, using the Teams app\, on 23 March from 14.00 – 17.00. \n\n\n\nSpeakerTitle14.00Chair: Jan van Hest (ICMS) Samuel Sánchez (IBEC)Opening and welcomeSuccessful joint ventures 14.05Shidong Song and Richard Post (IBEC & ICMS)Partnership between:Group lead IBEC: Samuel SánchezGroup lead ICMS: Remco van der Hofstad and Jan van HestEngineering transient dynamics of artificial cells by stochastic distribution of enzymes14.30Sertan Sukas (IBEC & ICMS)Partnership between:Group lead IBEC: Josep Samitier (IBEC)Group lead ICMS: Vito Conte\, Jaap den Toonder and Regina LuttgeAdvanced flow control and quantification of forces for mechanobiology studies14.55Tania Patiño Padial (IBEC→ICMS)Tania was a member of the group of Samuel Sánchez at IBEC and is now a member of the group of Jan van Hest at ICMSBioengineering life-like nanosystems for biomedical applications15.20Break Flash talks Exchange program 15.30Robert Dassen (ICMS→IBEC)Partnership between:Group leads IBEC: Veronika Magdanz and Samuel SánchezGroup lead ICMS: Hans Wyss3D printing of organ models for in vitro testing of microrobots15.38Lisa van Slagmaat (ICMS→IBEC)Partnership between:Group lead IBEC: Josep SamitierGroup lead ICMS: Jaap den ToonderMicrofluidic herringbone device with self-assembled antibody monolayer for CTC separation15.46Floor Ummels (ICMS→IBEC)Partnership between:Group lead IBEC: Giuseppe BattagliaGroup lead ICMS: Willem MulderCrossing the blood-brain barrier15.54Lisa Pomp (ICMS→IBEC)Partnership between:Group leads IBEC: José Antonio Del Río and Karen WellsGroup lead ICMS: Vito ConteEstablishment of an in vitro blood-brain barrier model on transwells for transendothelial transport studies16.04Stan van Wetten (ICMS→IBEC)Partnership between:Group lead IBEC: Sílvia PujalsGroup lead ICMS: Arthur de JongCorrelating Light and Electron Microscopy for PLGA-PEG nanoparticle charactization16.12Laura van de Koppel (ICMS→IBEC)Partnership between:Group leads IBEC: Elisabeth Engel and Bárbara BlancoGroup lead ICMS: Patricia DankersEngineering a 3D model of lymphoma using a hydrogel for precise screening of therapeutics16.20Break 16.35Roger Riera Brillas (IBEC & ICMS)Roger was a member of the  group of Lorenzo Albertazzi at IBEC and is now a member of the group of Lorenzo Albertazzi at ICMS Live-cell uPAINT imaging of receptors17.00Closing remarks 
URL:https://ibecbarcelona.eu/event/icms-ibec-joint-online-symposium/
CATEGORIES:Joint seminar / workshop / symposium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220325T100000
DTEND;TZID=Europe/Madrid:20220325T120000
DTSTAMP:20260404T004036
CREATED:20220316T105655Z
LAST-MODIFIED:20220316T105655Z
UID:96562-1648202400-1648209600@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Alejandro Mayorca
DESCRIPTION:Mapping the structure of the extracellular matrix and engineering matrixbased disease models\nAlejandro Mayorca\, Biotech Research and Innovation Centre\, University of Copenhagen \nUnderstanding disease necessitates a precise representation of the extracellular matrix (ECM)\, a vast\, intricate structure made of ~1300 interwoven proteins and glycans supporting all organs and acting as a master cell regulator. In spite of its importance\, there are no high-resolution maps of ECM topography. I will present methods to isolate ECM from mammalian organs and generate a precise\, quantitative\, three-dimensional representation of the ECM in human organs during health and incurable conditions. Further development of these methods uses ECM scaffolds to engineer experimental models that recreate cell niches associated to advanced disease\, aiming to break down the rules of their assembly. \n\nAlejandro Mayorca is an assistant professor at the Biotech Research and Innovation Centre of Copenhagen University. His work focuses on extracellular matrix research and cancer bioengineering. He is an alumnus of the Central University of Venezuela\, obtained his PhD in medical sciences from the University of Ehime\, Japan and later became a postdoc in Janine Erler’s lab at the University of Copenhagen. He isolated and characterised the structure of the extracellular matrix in primary and metastatic tumours (Nature Medicine\, 2017)\, developed techniques for whole-body ECM mapping (Nature Protocols\, 2019) and then designed ECM-based bioreactors to model lung and liver metastasis (Advanced Healthcare Materials\, 2022). \nSala Baobab\, Tower I\, 11 Floor\, IBEC
URL:https://ibecbarcelona.eu/event/ibec-seminar-alejandro-mayorca-2/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220325T100000
DTEND;TZID=Europe/Madrid:20220325T120000
DTSTAMP:20260404T004036
CREATED:20220316T105655Z
LAST-MODIFIED:20220316T105655Z
UID:91013-1648202400-1648209600@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Alejandro Mayorca
DESCRIPTION:Mapping the structure of the extracellular matrix and engineering matrixbased disease models\nAlejandro Mayorca\, Biotech Research and Innovation Centre\, University of Copenhagen \nUnderstanding disease necessitates a precise representation of the extracellular matrix (ECM)\, a vast\, intricate structure made of ~1300 interwoven proteins and glycans supporting all organs and acting as a master cell regulator. In spite of its importance\, there are no high-resolution maps of ECM topography. I will present methods to isolate ECM from mammalian organs and generate a precise\, quantitative\, three-dimensional representation of the ECM in human organs during health and incurable conditions. Further development of these methods uses ECM scaffolds to engineer experimental models that recreate cell niches associated to advanced disease\, aiming to break down the rules of their assembly. \n\nAlejandro Mayorca is an assistant professor at the Biotech Research and Innovation Centre of Copenhagen University. His work focuses on extracellular matrix research and cancer bioengineering. He is an alumnus of the Central University of Venezuela\, obtained his PhD in medical sciences from the University of Ehime\, Japan and later became a postdoc in Janine Erler’s lab at the University of Copenhagen. He isolated and characterised the structure of the extracellular matrix in primary and metastatic tumours (Nature Medicine\, 2017)\, developed techniques for whole-body ECM mapping (Nature Protocols\, 2019) and then designed ECM-based bioreactors to model lung and liver metastasis (Advanced Healthcare Materials\, 2022). \nSala Baobab\, Tower I\, 11 Floor\, IBEC
URL:https://ibecbarcelona.eu/event/ibec-seminar-alejandro-mayorca-3/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:IBEC Seminar
END:VEVENT
END:VCALENDAR