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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210909T113000
DTEND;TZID=Europe/Madrid:20210909T133000
DTSTAMP:20260405T214759
CREATED:20210727T101114Z
LAST-MODIFIED:20210727T101114Z
UID:86553-1631187000-1631194200@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Adrianna Glinkowska
DESCRIPTION:Formulation and screening of drug nanocarriers using microfluidic technology\nAdrianna Glinkowska\, Nanoscopy for nanomedicine \nThe defence will take place online\, if you wish to attend to this defence you can find the link and more information here \n 
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-adrianna-glinkowska/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210903T110000
DTEND;TZID=Europe/Madrid:20210903T130000
DTSTAMP:20260405T214759
CREATED:20210811T082116Z
LAST-MODIFIED:20210811T082205Z
UID:86797-1630666800-1630674000@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Ana Candida Lopes Hortelão
DESCRIPTION:Enzyme Powered Nanomotors Towards Biomedical Applications\nAna Candida Lopes Hortelão\, Smart Nano-bio-devices group \nThe defence will take place online\, if you wish to attend to this defence you can find the link and more information here
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-ana-candida-lopes-hortelao/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210716T100000
DTEND;TZID=Europe/Madrid:20210716T120000
DTSTAMP:20260405T214759
CREATED:20210628T090824Z
LAST-MODIFIED:20210628T105106Z
UID:85642-1626429600-1626436800@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Pau Gorostiza
DESCRIPTION:Electrochemically Gated Charge Transport in Redox Proteins and Photosynthetic Complexes\n\nPau Gorostiza\, group leader of the Nanoprobes and nanoswitches group at IBEC \nInterprotein electron transport is an essential process in cell respiration and photosynthesis. It takes place between redox proteins and complexes\, and it displays an outstanding efficiency and environmental adaptability. Although the biochemistry of electron transport processes is well characterized\, nanoscale experimental methods are needed to understand electronic pathways in these redox protein structures\, both for fundamental and for technological purposes. Electrochemical scanning tunneling microscopy (ECSTM) is an excellent tool to study electronic materials and redox molecules including proteins. It offers single molecule resolution and allows working in aqueous solution\, in nearly physiological conditions in the case of proteins\, and under full electrochemical control. ECSTM also allows performing conductance measurements by current-potential and current-distance tunneling spectroscopy. An overview of these methods and current projects in the laboratory will be presented\, with special emphasis on cytochromes of the respiratory chain and on photosystem I complexes. \nMore information about Pau Gorostiza’s research here \nThis seminar will be held using the TEAMS app
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-pau-gorostiza/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210709T100000
DTEND;TZID=Europe/Madrid:20210709T120000
DTSTAMP:20260405T214759
CREATED:20210628T090521Z
LAST-MODIFIED:20210628T105718Z
UID:85638-1625824800-1625832000@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Xavier Fernàndez-Busquets
DESCRIPTION:Nanomalaria group: 20 years at IBEC\nXavier Fernàndez-Busques\, group leader of the Nanomalaria group at IBEC \nWe will start by briefly looking at the origins of our group back in 2001 as part of IBEC’s embryo\, the Research Center for Bioelectronics and Nanobioscience. Our current activities integrate two decades of cumulative research oriented to the development of targeted nanocarriers for parasitic diseases with focus on malaria but currently expanding to leishmaniasis. \nBecause eventual antimalarial nanomedicines need to be deployed in low per capita income regions\, their final components must take into account this particular economic landscape. Liposomes and polymeric nanocarriers offer advantages and suffer from limitations depending on the severity of the disease in each particular clinical case. Entering erythrocytes\, the host cell of Plasmodium in the blood circulation\, is a challenge in itself due to their lack of endocytic processes. Antibodies\, polysaccharides like heparin\, synthetic polymers and DNA aptamers have been used to target and eventually penetrate red blood cells. \nFinally\, we have recently launched an effort to discover new antimalarial drugs that should constitute the third and final element in the design of targeted nanocarriers for malaria. The know-how acquired in the development of nanocapsules\, targeting elements and drugs has the capacity of being exported to other infectious diseases. Because\, no matter how cost-efficient you can make a nanomedicine\, clinical trials will significantly increase its cost\, we are exploring a radical alternative: designing nanocarriers to target the parasites in their arthropod vectors. \nMore information about Xavier’s research here \nThis seminar will be held using the TEAMS app \n 
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-xavier-fernandez-busquets/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210702T100000
DTEND;TZID=Europe/Madrid:20210702T120000
DTSTAMP:20260405T214759
CREATED:20210628T090118Z
LAST-MODIFIED:20210629T084516Z
UID:85634-1625220000-1625227200@ibecbarcelona.eu
SUMMARY:PhD Discussions: Ignasi Granero
DESCRIPTION:Ignasi Granero\, Celular and molecular mechanobiology group \nIn eukaryotic cells\, the cell nucleus contains the DNA and directs the reaction to important signalling cascades\, both biochemical and biomechanical. At the Cellular and Molecular Mechanobiology lab we study how forces and the physical characteristics of the cell environment affect cell behaviour and homeostasis. In my case\, I am interested in how the cell nucleus senses physical changes and triggers a cell response to them.\nFor this purpose\, we have engineered a battery of fluorescent proteins\, which change their location depending on the physical state of the nucleus. Higher forces in the nucleus correspond with higher nuclear accumulation of these proteins. Indicating that these proteins react to mechanical/morphological stimuli. Then\, we have chosen the variant that can be used as a mechano-sensor. Currently\, we are testing the sensor in single- and multi-cell approaches to understand its behaviour in different systems and the ruling principles under its functioning. \nThis PhD Discussion will be held online using the GoToMeeting app
URL:https://ibecbarcelona.eu/event/phd-discussions-ignasi-granero/
CATEGORIES:PhD Discussions Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210701T093000
DTEND;TZID=Europe/Madrid:20210701T120000
DTSTAMP:20260405T214759
CREATED:20210622T093545Z
LAST-MODIFIED:20210622T093651Z
UID:85344-1625131800-1625140800@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Ferran Velasco
DESCRIPTION:Carboxymethyl cellulose-based cryogels as scaffolds for pancreatic and skeletal muscle tissue engineering\nFerran Velasco\, Biosensors for bioengineering group \nThe defence will take place online\, if you wish to attend to this defence\, you have to send an email to doctoratmedicina@ub.edu and you  can find more information here \n 
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-ferran-velasco/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210628T100000
DTEND;TZID=Europe/Madrid:20210628T120000
DTSTAMP:20260405T214759
CREATED:20210621T135519Z
LAST-MODIFIED:20210621T135842Z
UID:85281-1624874400-1624881600@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Maria Arista
DESCRIPTION:Unveiling viral structures by single-molecule localization microscopy\nMaria Arista\, Nanoscopy for nanomedicine group \nThe defence will take place online\, if you wish to attend to this defence\, you can find the link to access here and you can find more information here
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-maria-arista/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210623T100000
DTEND;TZID=Europe/Madrid:20210623T120000
DTSTAMP:20260405T214759
CREATED:20210622T131947Z
LAST-MODIFIED:20210622T131947Z
UID:85480-1624442400-1624449600@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Xarxa Quiroga
DESCRIPTION:Plasma membrane mechanosensing upon stretch-induced topography remodelling\nXarxa Quiroga\, Cellular and molecular mechanobiology group. \nThe thesis defence takes place tomorrow at 10AM in the “Antoni Caparrós” auditorium\, located at the PCB Tower D\, with limited capacity.
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-xarxa-quiroga/
LOCATION:Auditori Antoni Caparrós – PCB
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210618T100000
DTEND;TZID=Europe/Madrid:20210618T120000
DTSTAMP:20260405T214759
CREATED:20210611T070229Z
LAST-MODIFIED:20210611T070255Z
UID:84958-1624010400-1624017600@ibecbarcelona.eu
SUMMARY:IBEC Online Seminar: Jessica Ilenburg
DESCRIPTION:Tissue Engineering in Microgravity\nJessica Ilenburg\, Gravitational Biotechnologist at Yuri gravity \nTissue Engineering and regenerative medicine are two fast growing and fast moving research fields. With the invention of bioprinting and tissue chips two breakthrough innovations have been made and now research in microgravity (for example on the ISS) promises even more and faster progress. A lot of advantages\, like less contact inhibition and unrestrained growth in all 3 dimensions make the cell structures grow bigger and more complex. This presentation focuses on the qualities of the unique research environment of microgravity and introduces a couple of research findings. \nJessica Ilenburg is doing her master studies in molecular biotechnology at Bielefeld University in Germany. Currently she is working at yuri GmbH as a gravitational biotechnologist focusing on Tissue Engineering\, bioprinting and protein crystal growth in microgravity. Previously she has worked at the Novo Nordisk Foundation Center for Biosustainability in Copenhagen working with thermophilic organisms and isolating proteins of the butanol pathway.
URL:https://ibecbarcelona.eu/event/ibec-online-seminar-jessica-ilenburg/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210608T080000
DTEND;TZID=Europe/Madrid:20210613T170000
DTSTAMP:20260405T214759
CREATED:20210607T145823Z
LAST-MODIFIED:20210607T145823Z
UID:84812-1623139200-1623603600@ibecbarcelona.eu
SUMMARY:Biennal Ciutat i Ciència
DESCRIPTION:Durant els dies 8 i 13 de juny tindrà lloc la segona edició de la Biennal Ciutat-Ciència de Barcelona\, i l’IBEC serà un dels centres que hi contribuirà\, a través dels seus experts. A més a més\, aquesta Biennal culmina amb la 14ª edició de la Festa de la Ciència\, amb moltes propostes per viure la ciència en primera persona.\n \nDes de l’IBEC\, diversos experts participen en les activitats programades per enguany: \n\nSamuel Sánchez\, Professor de Recerca ICREA\, i líder del grup “Smart Nano-bio-devices”\, paraticipa a   – “Pecha Kucha express: art\, ciència\, tecnologia”\nNuria Montserrat\, participa amb una  micro-xerrada sobre “Miniòrgans humans per entendre la covid-19”\nL´Anke Kleff\, Senior HR Development Officer a l´IBEC\, participarà en una taula rodona sobre “Expandim l´influència de la dona a la ciència”\, dins d’una nova Trobada de #100tífiques
URL:https://ibecbarcelona.eu/event/biennal-ciutat-i-ciencia-4/
CATEGORIES:Outreach / Fair / Festival
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210604T143000
DTEND;TZID=Europe/Madrid:20210604T180000
DTSTAMP:20260405T214759
CREATED:20210513T114527Z
LAST-MODIFIED:20210513T114410Z
UID:84281-1622817000-1622829600@ibecbarcelona.eu
SUMMARY:M-CELS Workshop Barcelona Satellite
DESCRIPTION:EMBL and IBEC aim to contribute to the discussion on challenges and opportunities in the expanding field of Multi-cellular engineered living systems (M-CELS). \nWe have organized a satellite session to the M-CELS Workshop 2021 organized by the Center for Emergent Behaviors of Integrated Cellular Systems. The session aims also to be an appetizer to the 2nd EMBL-IBEC Winter Conference on Engineering Multicellular Systems to be held on 9-11th February 2022 in Barcelona. \n\n\n\n\n\n\n\n\nMulti-cellular engineered living systems are purpose-driven living systems with multiple interacting living components. They are engineered for specific goals or functions but take emergence into account during the design process\, allowing the final system to emerge through natural and non-natural biological processes. M-CELS research is intended to provide a fundamental engineering understanding that enables a quantitative approach bridging between single cells and organs or organisms. The field is still developing\, so M-CELS as a field of research is still rapidly expanding \nRegistration here
URL:https://ibecbarcelona.eu/event/m-cels-workshop-barcelona-satellite/
CATEGORIES:Joint seminar / workshop / symposium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210525T030000
DTEND;TZID=Europe/Madrid:20210525T170000
DTSTAMP:20260405T214759
CREATED:20210518T071812Z
LAST-MODIFIED:20210518T071846Z
UID:84387-1621911600-1621962000@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Enara Larrañaga
DESCRIPTION:Effects of substrate-derived cues in driving the self-organization of organoid-derived intestinal epithelia\nEnara Larrañaga\, Biomimetic systems for cell engineering \nThe defence will take place online\, if you wish to attend to this defence\, you can find the link to access here and you can find more information here \n 
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-enara-larranaga/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210521T093000
DTEND;TZID=Europe/Madrid:20210521T133000
DTSTAMP:20260405T214759
CREATED:20210408T144743Z
LAST-MODIFIED:20210408T145058Z
UID:83289-1621589400-1621603800@ibecbarcelona.eu
SUMMARY:Research4Talent 2021
DESCRIPTION:On Friday 21st May we’ll open our doors virtually to UNDERGRADUATE & MASTER’s students interested in a research career\n \n  \nThe day is a chance for you to talk to our researchers and ask them questions about their day-to-day work in the lab\, career paths\, work-life balance\, mobility etc\, as well as a visit to our labs. \nIn 2020 IBEC signed more that 120 internship agreements for Undergraduate and Master Students with a wide range of national and international universities. \nThis year’s edition will be held virtually. If you are interested in IBEC’s seventh edition of reSEARCH4TALENT please stay connected\, we will soon provide more info with the links to acces the event. \nVisit the website here \n 
URL:https://ibecbarcelona.eu/event/research4talent-2021/
CATEGORIES:Outreach / Fair / Festival
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210514T100000
DTEND;TZID=Europe/Madrid:20210514T120000
DTSTAMP:20260405T214759
CREATED:20210506T071033Z
LAST-MODIFIED:20210506T074133Z
UID:84141-1620986400-1620993600@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Mónica Marro
DESCRIPTION:A new molecular dimension: exploiting Raman spectroscopy in Biomedicine\nMónica Marro\, ICFO\, The Institute of Photonic Sciences\n \nRaman spectroscopy is a promising optical technique that enables the investigation of the molecular content of biological samples in a rapid\, non-invasive\, label-free and multiplexed approach. In the biomedical field\, it is of special interest because the device can be portable and cost-effective. \nIn this seminar\, I will show my work exploiting Raman spectroscopy in a broad range of biomedical applications from the molecular\, to cellular and tissue level. I will present how Raman spectroscopy can represent a step forward into different fields\, namely: cancer diagnosis\, patient stratification\, and personalized medicine; neurodegeneration; and mechanobiology. I will show also optical developments that can improve Raman spectroscopy in the speed of image acquisition\, like the Raman light sheet approach\, or Surface Enhanced Raman spectroscopy. \nOverall\, I will show how Raman spectroscopy coupled with data science and developments in photonics and nano-engineering could revolutionize the biomedical field in the next years\, providing new and other-wise inaccessible molecular information\, and giving an unprecedented step towards a more rapid\, accurate\, personalized diagnosis and treatments.
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-monica-marro/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210512T100000
DTEND;TZID=Europe/Madrid:20210512T120000
DTSTAMP:20260405T214759
CREATED:20210507T092710Z
LAST-MODIFIED:20210507T094146Z
UID:84243-1620813600-1620820800@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Harishankar Balakrishnan
DESCRIPTION:Nanoscale Tomography based in Electrostatic Force Microscopy\nHarishankar Balakrishnan\, Nanoscale bioelectrical characterization group \nThe defence will take place online\, if you wish to attend to this defence\, you can find the link to access here and you can find more information here \nPlease join the meeting few minutes before the mentioned time to avoid session interruption.  \nIf you are joining after the mentioned time\, please make sure your microphone is muted before joining the session.
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-harishankar-balakrishnan/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210511T100000
DTEND;TZID=Europe/Madrid:20210511T120000
DTSTAMP:20260405T214759
CREATED:20210507T154643Z
LAST-MODIFIED:20210507T154643Z
UID:84258-1620727200-1620734400@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Martina Di Muzio
DESCRIPTION:Nanoscale dielectric mapping of biomembranes with in-liquid Scanning Dielectric Microscopy\nMartina Di Muzio\, Nanoscale bioelectrical characterization group \nThe defence will take place online\, if you wish to attend to this defence\, you can find the link to access here and you can find more information here \nPlease join the meeting few minutes before the mentioned time to avoid session interruption. \nIf you are joining after the mentioned time\, please make sure your microphone is muted before joining the session.
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-martina-di-muzio/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210430T100000
DTEND;TZID=Europe/Madrid:20210430T120000
DTSTAMP:20260405T214759
CREATED:20210419T121756Z
LAST-MODIFIED:20210420T103321Z
UID:83514-1619776800-1619784000@ibecbarcelona.eu
SUMMARY:PhD Discussion Sessions: Teodora Andrian and Xavier Arqué
DESCRIPTION:Correlating super-resolution microscopy and transmission electron microscopy for nanoparticle characterisation\nTeodora Andrian\, Nanoscopy for nanomedicine group \nThe functionalization of nanoparticles with surface functional moieties is a key strategy to achieve bioactivity and cell targeting in nanomedicine. The interplay between size and ligand number and distribution is crucial for the formulation performance and needs to be properly characterized to understand nanoparticle structure-activity relations. However\, the particle-to-particle heterogeneity poses a serious challenge due to the lack of methods able to measure both size and ligand number and distribution at the same time and at the single particle level. Here we address this issue by introducing a correlative method combining super-resolution microscopy (SRM) and transmission electron microscopy (TEM) imaging. Correlative light and electron microscopy (CLEM) techniques proved their potential in structural biology but to the best of our knowledge\, they have not yet been explored for the structural characterization of nanoparticles. Here we apply our super-resCLEM method to characterize the relationship between size and ligand number\, and ligand density in PLGA-PEG nanoparticles at the single particle and single-molecule level.  We highlight how heterogeneity found in nanoparticle size can impact ligand distribution\, and we discuss the implications on formulation performance. We show how a significant part of the nanoparticle population goes completely undetected in the single-technique analysis\, demonstrating that the characterization of nanomaterials using a multiparametric correlative method outplays the information obtained compared to a one-method-at-a-time approach. Using SRM alone\, we demonstrated how PEG architecture can influence ligand conjugation efficiency and accessibility. The applicability of our method spans beyond PLGA-PEG nanoparticles and holds great promise for the multiparametric analysis of several other parameters and nanomaterials. \nUnraveling the fundamental aspects of enzyme-powered micromotors\nXavier Arqué\, Smart Nano-Bio-Devices group \nEnzyme-coated micro- and nanomotors self-propel by the biocatalytic conversion of substrates into products and show great promise as actively navigating agents in the fields of biomedicine and environmental applications. However\, many of the fundamental aspects underlying enzyme-powered self-propulsion have yet to be fully understood and are crucial for their optimal implementation. Under this framework\, this research is focused on elucidating and studying the intrinsic (catalytic turnover or structural flexibility) and extrinsic (bulk and local ionic media) enzymatic properties that lead to an improved active motion powered by bio-catalysis. This is enabled by exploring novel types of both i) enzymes that can act as active motion engines and ii) platforms with appealing properties to be used as chassis of enzymatic micro- and nanomotors. Overall\, this work contributes to a better understanding of the mechanism of motion of enzymatic active motion\, expands the current library of enzymatic engines and chassis materials available\, and provides new insights into the feasibility of implementation of enzyme-powered micro- and nanomotors. \nThe session will be held online using the GoToMeeting Platform
URL:https://ibecbarcelona.eu/event/phd-discussion-sessions-teodora-andrian-and-xavier-arque/
CATEGORIES:PhD Discussions Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210426T100000
DTEND;TZID=Europe/Madrid:20210426T120000
DTSTAMP:20260405T214759
CREATED:20210422T071047Z
LAST-MODIFIED:20210422T071132Z
UID:83625-1619431200-1619438400@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Laura Moya
DESCRIPTION:Deciphering the utility of Galleria mellonella as an infection and toxicity in vivo model\nLaura Moya\, Bacterial infections: Antimicrobial therapies \nThe defence will take place online\, if you wish to attend to this defence\, you will find the link to access and all the information here
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-laura-moya/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210416T100000
DTEND;TZID=Europe/Madrid:20210416T120000
DTSTAMP:20260405T214759
CREATED:20210409T065700Z
LAST-MODIFIED:20210409T065700Z
UID:83305-1618567200-1618574400@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Núria Blanco-Cabra
DESCRIPTION:Noves metodologies per al tractament de bacteris creixent en forma de biofilm\nNúria Blanco-Cabra\, Bacterial infections and antimicrobial therapies group at IBEC \nThe defence will take place online\, if you wish to attend to this defence\, write an email to doctoratmedicina@ub.edu at least 48 hours before the defence.
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-nuria-blanco-cabra/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210416T100000
DTEND;TZID=Europe/Madrid:20210416T120000
DTSTAMP:20260405T214759
CREATED:20210329T143157Z
LAST-MODIFIED:20210407T090510Z
UID:83098-1618567200-1618574400@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Núria Montserrat
DESCRIPTION:Study on the of the interplay between glucose metabolism and SARS-CoV-2 infection exploiting human kidney organoids\n \nNúria Montserrat\, group leader “Pluripotency for organ regeneration” at IBEC \nSevere acute respiratory syndrome 2 (SARS-CoV-2) infection leads to a high risk of hospitalization and mortality in diabetic patients. SARS-CoV-2 binds to angiotensin-converting enzyme 2 (ACE2) receptor\, which is expressed in key metabolic organs such as pancreas\, muscle\, heart\, adipose tissue\, the small intestine\, and the kidneys. As a result\, it is likely that SARS-CoV-2 may cause alterations of glucose metabolism that could complicate the pathophysiology of pre-existing diabetes or lead to new mechanisms of disease. \nThanks to an international collaboration we have previously shown that SARS-CoV-2 can directly infect engineered human blood vessel organoids and human kidney organoids. In these last months we have started to collectively addressed how to study on the interplay between glucose metabolism and SARS-CoV-2 infections making use of kidney organoid technology. We have first developed culture regime conditions in human kidney organoids mirroring cellular responses similar to those encountered in the human diabetic kidney. Through an exhaustive characterization including single cell RNA profiling and ulterior validation in organoids and kidney patient cells we are starting to dissect the different transcriptional programs that are differently regulated in these different contexts. To further assess on the key role of ACE2 in these processes we have make use of CRISPR/Cas9 technology to generate human pluripotent stem cells lines knock out (KO) for ACE2. Kidney organoids ACE2KO have been further subjected to SARS-CoV-2 infections in normoglycemic and oscillatory glucose conditions further demonstrating the central role of ACE2 in early steps of infection in these organoid model systems. Thanks to our international collaborators we have also explored on the role of ACE2 in early steps of SARS-CoV-2 infection in other organoid platforms including gastric and vascular organoids. \nTogether\, our results provide evidence that SARS-CoV-2 infection altered glucose metabolism and support the use of kidney organoids as a platform to investigate the cellular susceptibility\, disease mechanisms\, and treatment strategies for SARS-CoV-2 infection in hyperglycaemic condition. \nMore information about Núria Montserrat’s research here \nThis seminar will be held using the GoToMeeting Platform
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-nuria-montserrat/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210407T100000
DTEND;TZID=Europe/Madrid:20210407T120000
DTSTAMP:20260405T214759
CREATED:20210326T095201Z
LAST-MODIFIED:20210326T095226Z
UID:83020-1617789600-1617796800@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Patrica Prado Peralta
DESCRIPTION:Developing new strategies to understand human kidney development and target human disease\nPatricia Prado Peralta\, Pluripotency for organ regeneration group \nThe defence will take place online using the BBCollab platform
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-patrica-prado-peralta/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210326T100000
DTEND;TZID=Europe/Madrid:20210326T120000
DTSTAMP:20260405T214759
CREATED:20210315T105812Z
LAST-MODIFIED:20210315T105812Z
UID:82816-1616752800-1616760000@ibecbarcelona.eu
SUMMARY:PhD Discussions Sessions: Héctor López Carral
DESCRIPTION:Subjective ratings of emotive stimuli predict the impact of the COVID-19 quarantine on affective states\nHéctor López Carral\, SPECS lab\, IBEC \nThe COVID-19 crisis resulted in a large proportion of the world’s population having to employ social distancing measures and self-quarantine. Given that limiting social interaction impacts mental health\, we assessed the effects of quarantine on emotive perception as a proxy of affective states. To this end\, we conducted an online experiment whereby 112 participants provided affective ratings for a set of normative images and reported on their well-being during COVID-19 self-isolation. We found that current valence ratings were significantly lower than the original ones from 2015. This negative shift correlated with key aspects of the personal situation during the confinement\, including working and living status\, and subjective well-being. These findings indicate that quarantine impacts mood negatively\, resulting in a negatively biased perception of emotive stimuli. Moreover\, our online assessment method shows its validity for large-scale population studies on the impact of COVID-19 related mitigation methods and well-being. \nThe PhD discussions session will be held ONLINE at the GoToMeeting platform
URL:https://ibecbarcelona.eu/event/phd-discussions-sessions-hector-lopez-carral/
CATEGORIES:PhD Discussions Session
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210319T100000
DTEND;TZID=Europe/Madrid:20210319T120000
DTSTAMP:20260405T214759
CREATED:20210203T121424Z
LAST-MODIFIED:20210315T124852Z
UID:81339-1616148000-1616155200@ibecbarcelona.eu
SUMMARY:Clinical Colloquia: Anna Novials
DESCRIPTION:Diabetes\, where are we?\nAnna Novials\, PI of the group “Pathogenesis and Prevention of Diabetes” at IDIBAPS/Clinic Hospital of Barcelona and member of CIBERDEM network. \nDiabetes mellitus (DM) is a group of chronic metabolic disorders all characterized by hyperglycemia. It occurs either when the pancreas does not produce enough insulin or when the peripheral tissues cannot effectively use the insulin it produces. The global prevalence of diabetes and impaired glucose tolerance (the intermediate transition between normal blood glucose levels and diabetes) has been increasing over recent decades. The International Diabetes Federation (IDF) reported that in 2019 there were 463 million people between 20-79 years worldwide with diabetes\, accounting for the 9.3 % of the global adult population. If this trend continues\, it is expected to increase to 700 million by 2045. Furthermore persistent high blood glucose levels cause generalized vascular damage affecting the kidneys (nephropathy)\, the eyes (retinopathy)\, the nerves (neuropathy) and the heart (cardiovascular disease)\, leading to disabilities and premature death. The World Health Organization (WHO) reported diabetes to be the seventh leading cause of death. As a consequence the economic burden of diabetes has a high impact on the global health-care system. \nThe first national study in Spain published in 2012 (the Di@bet.es Study) revealed that the overall prevalence of DM in individuals ≥18 years old in our country was 13.8% and\, about a half of them (6%) had unknown diabetes. In addition to this alarming values\, the prevalence rates of isolated impaired fasting glucose (IFG)  and isolated impaired glucose tolerance (IGT)  3.4% and 9.2%\, respectively (2). Taken together\, this study uncovered that almost 30% of the study population had some carbohydrate disturbance. \nType 2 Diabetes (T2D) accounts for the vast majority (around 90%) of diabetes worldwide. It can be effectively managed through education\, adoption of healthy lifestyles\, combined with medication as required. The pathogeny of T2D is extremely complex and comprises all the organs that work coordinately to maintain energy and glucose homeostasis.  It is established that when the cross-talk between organs (pancreas\, liver\, muscle\, adipose tissue\, brain \,etc )is altered\, then the main pathogenic events which are insulin secretory defects and insulin resistance appear as a hallmark of T2D. All current treatment for T2D are adressed to  target molecular pathways in different tissues. \nType 1 diabetes (T1D) is the major cause of diabetes in childhood. Patients need an uninterrupted supply of insulin for life. The pathogeny of diabetes consists in alteration in the autoinmunity. The main cause is not yet been stablished. The advances in the treatment remain  dissapointing . Although technology applied to diabetes is in continuos progress\, patients are still using the same treatment as 100 years ago\, when insulin was discovered. \nCollectively\, these results  evidence the need for more clinical and preventive intervention programs and highlight the importance of carrying out more basic research in order to understand the underlying mechanisms of the disease. \n\nDr. Anna Novials is endocrinologist at Hospital Clinic de Barcelona and  leader group of research at IDIBAPS. She received her PhD from the University of Barcelona\, in 1989\, focusing her studies on the chronic effect of glucotoxicity on pancreatic function in patients with type 2 diabetes. A postdoctoral stay at the University of Cambridge and collaborations with the University of Oxford enriched her scientific and technical knowledge of molecular biology\, turning her research objectives toward the molecular mechanisms that affect pancreatic islet function in diabetes\, which she would then develop at the Hospital Clinic de Barcelona\, going on to lead her own research group. \nFrom 1998 to 2008\, Dr. Novials conducted her clinical activity at the Sardà Farriol Foundation in Barcelona\, first as Head of the Diabetology Unit and later as Executive Director. Here she devoted her efforts to promoting educational tools to help patients adhere to exercise programs as part of their diabetes treatment plan. In 2008\, she rejoined the IDIBAPS as leader of a clinical and basic research team. Since 2010\, she has also served as an Executive Committee member of the Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM). Finally\, Dr. Novials is the former  President of the Spanish Diabetes Society and as served as member of the EASD-EU Committee of the European Association for the Study of Diabetes to advocate for diabetes research. \nThis clinical colloquia will take place online at the GoToMeeting platform
URL:https://ibecbarcelona.eu/event/clinical-colloquia-anna-novials/
CATEGORIES:IBEC Seminar
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210312T100000
DTEND;TZID=Europe/Madrid:20210312T120000
DTSTAMP:20260405T214759
CREATED:20210203T123720Z
LAST-MODIFIED:20210303T105835Z
UID:81355-1615543200-1615550400@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Paolo Arosio
DESCRIPTION:Membraneless compartments based on intrinsically disordered proteins: from biology towards new protein materials\nPaolo Arosio\, Institute for Chemical and Bioengineering\, ETH Zurich \nIn the last few years\, discoveries in biology are revealing that a class of intrinsically disordered protein sequences plays an important role in the formation of cellular membraneless compartments by spontaneous liquid-liquid phase separation of proteins and nucleic acids. These compartments underlie several important functions and can act as microreactors\, in which environment and composition are carefully regulated in space and time. These observations inspired us to exploit these biological sequences to mimic these membraneless compartments on the bench\, towards the development of high-performance open microreactors\, with applications for instance in biocatalysis. With these sequences we can regulate not only the dynamic process of phase separation but also several properties of the resulting compartments\, including uptake of client molecules\, polarity and material properties. With this control we can\, in turn\, regulate biochemical reactions occurring within the compartments. \nWe further show the development of droplet microfluidic platforms to characterize multiple properties of the open compartments\, including both thermodynamics and dynamics of phase separation. We illustrate these concepts by investigating an established in vitro model of Processing bodies consisting of the phase separation of the DEAD-box protein ATPase Dhh1 in the presence of ATP and RNA. \nThis seminar will take place online \nKnow more about Paolo Arosio’s research here
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-paolo-arosio/
CATEGORIES:IBEC Seminar
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210310T120000
DTEND;TZID=Europe/Madrid:20210310T140000
DTSTAMP:20260405T214759
CREATED:20210218T161413Z
LAST-MODIFIED:20210301T092607Z
UID:81895-1615377600-1615384800@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Ester Caffarel
DESCRIPTION:Breaking Paradigms: Delivering insulin orally\nEster Caffarel\, MIT \nBiologics have revolutionized disease treatment; however\, their rapid degradation and poor absorption in the gastrointestinal (GI) tract generally limit their administration to parenteral routes. Devices for the oral delivery of biologics must aid in both localization and permeation to achieve systemic drug uptake. For this purpose\, we have developed various ingestible devices that rapidly propel drug-loaded posts into the tissue wall of the different organs of the GI tract.
URL:https://ibecbarcelona.eu/event/online-ibec-seminar-ester-caffarel/
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210310T090000
DTEND;TZID=Europe/Madrid:20210310T230000
DTSTAMP:20260405T214759
CREATED:20210301T090512Z
LAST-MODIFIED:20210308T082914Z
UID:82191-1615366800-1615417200@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Maider Badiola
DESCRIPTION:Compartmentalised microfluidic culture systems for in vitro modelling of neurological and neuromuscular microenvironments\nMaider Badiola\, Nanobioengineering group \nMovement of skeletal-muscle fibres is generated by the locomotion circuit. Failures in any part of the circuit can cause or define the severity of neuromuscular diseases (NMD)\, such as amyotrophic lateral sclerosis (ALS). Conventional in vitro study models coculturing motoneurons and skeletal muscle cells are not physiologically relevant. Moreover\, studying fragments of the circuit cannot provide a comprehensive and complete view of the pathological process. \nThis thesis aims to study the neuromuscular context in vitro through compartmentalised microfluidic culture systems (cµFCS) and to create physiologically relevant study models. It offers an evolving prospective of in vitro models\, moving from mice to human cells\, from 2D to 3D cell cultures\, from primary cells to human induced pluripotent stem cells (hiPSC)\, and analysing both healthy and diseased cells. \nThis thesis gathers many technological innovations from a Bioengineering point of view\, paving the way for future studies in the neuromuscular field. It shows that the integration of the entire neuromuscular circuit components in the developed in vitro systems provides a wider view of the neuromuscular physiology and the pathological processes. These results show first steps towards future 3D physiological neuromuscular circuit models on a chip for NMD studies. \nThe defence will take place online using the Microsoft Teams Platform
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-maider-badiola/
CATEGORIES:PhD Thesis Defence
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210225T090000
DTEND;TZID=Europe/Madrid:20210225T120000
DTSTAMP:20260405T214759
CREATED:20210223T121026Z
LAST-MODIFIED:20210223T121801Z
UID:82042-1614243600-1614254400@ibecbarcelona.eu
SUMMARY:Barcelona Tribuna «La innovació\, la gestió del talent i la recerca científica a Barcelona»
DESCRIPTION:Emmarcat dins del cicle (Re)Imaginem Barcelona\, Barcelona Tribuna reuneix Jordi Marin\, director general de l’Associació Catalana d’Empreses Consultores (ACEC); Josep Samitier\, director de l’Institut de Bioenginyeria de Catalunya; Núria Bayó\, cap de programes acadèmics i eficàcia organitzativa del Barcelona Institute of Science and Technology (BIST); i Alexis Roig\, director del SciTech DiploHub\, per parlar de “La innovació\, la gestió del talent i la recerca científica a Barcelona“. \n 
URL:https://ibecbarcelona.eu/event/barcelona-tribuna-la-innovacio-la-gestio-del-talent-i-la-recerca-cientifica-a-barcelona/
CATEGORIES:External symposium / conference / congress
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210224T113000
DTEND;TZID=Europe/Madrid:20210224T133000
DTSTAMP:20260405T214759
CREATED:20210203T123103Z
LAST-MODIFIED:20210218T150416Z
UID:81350-1614166200-1614173400@ibecbarcelona.eu
SUMMARY:Nano Rare Diseases Day 2021
DESCRIPTION:Nano Rare Diseases Day es un evento organizado en el marco del Día Mundial de las Enfermedades Minoritarias donde se darán a conocer las últimas innovaciones en materia de Nanomedicina para el tratamiento y diagnóstico de dichas enfermedades\, con temas que van desde el diagnóstico precoz\, la liberación controlada de fármacos o el desarrollo de nuevas terapia\nDurante esta jornada\, expertos en Nanomedicina de diferentes campos -investigación\, empresa\, práctica clínica\, autoridades sanitarias\, pacientes\, etc.-\,  expondrán los últimos avances y nos darán la oportunidad de descubrir el generador de progreso que la Nanomedicina significa para la salud como creador de nuevas oportunidades en el diagnóstico y el tratamiento de las enfermedades minoritarias. \nMás información e inscripciones aquí
URL:https://ibecbarcelona.eu/event/nano-rare-diseases-day-2021/
CATEGORIES:Joint seminar / workshop / symposium
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210223T150000
DTEND;TZID=Europe/Madrid:20210223T170000
DTSTAMP:20260405T214759
CREATED:20210217T122107Z
LAST-MODIFIED:20210217T122142Z
UID:81819-1614092400-1614099600@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Davia Prischich
DESCRIPTION:Development and applications of photoswitchable small molecules and peptides to control protein-protein interactions and GPCR activity\nDavia Prischich\, Nanoprobes and Nanoswitches group\, IBEC \nThe defense will be held online through the platform provided by the UB. For those who are interested in joining\, please remember that you have to write an email to vd.quimica.recerca@ub.edu at least 48 hours before the event.
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-davia-prischich/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20210219T100000
DTEND;TZID=Europe/Madrid:20210219T120000
DTSTAMP:20260405T214759
CREATED:20210203T121136Z
LAST-MODIFIED:20210209T085017Z
UID:81329-1613728800-1613736000@ibecbarcelona.eu
SUMMARY:PhD Complementary Skills Session: Lab greening – how you can play your part!
DESCRIPTION:Lab greening – how you can play your part!\nUna FitzGerald\, Galway Neuroscience Centre\, Founder – ‘Galway Green Labs’ initiative \nDr FitzGerald will share her motivation for getting involved in promoting and implementing green lab practices at first\, within her own University in Galway\, and then\, across Ireland and Europe. She will describe the experience of recruiting researchers and technical staff to join a green team and how this idea has spread to other labs on-campus\, eventually being adopted as a University Strategy for 2020-2025. Some recommendations on how young researchers might go through the same process\, are provided. In the end\, the talk should encourage anyone working within the Biomedical Engineering sector\, to implement new protocols that will minimise the impact that their daily work has on the environment. \n\nAfter completing a BE (Ind Eng) and MSc in Biotechnology at NUIG\, Dr FitzGerald worked in the pharmaceutical sector for five years in France and the UK\, before embarking on a PhD in Molecular Biology at the University of Strathclyde\, Glasgow. Following a brief spell in cancer research\, on joining Prof. Sue Barnett’s lab in Glasgow Uni. she discovered her true passion – neuroscience and in particular\, research on brain disorders including multiple sclerosis and Parkinson’s disease. Since returning to the University in Galway\, Ireland\, Dr FitzGerald has built a track record in MS research\, is a funded investigator in CÚRAM\, the SFI Centre for Research on Medical Devices and is ex-director of the Galway Neuroscience Centre. She is the lead PI and Coordinator of a €3.9M EU-funded Innovative Training Network which is training 15 PhD students across Europe\, with the aim of developing a novel device for treating the progressive phase of MS. In 2019 she led the CÚRAM lab to be the first in Europe to gain Green Lab Certification from My Green Lab and she now chairs a national working group on sustainable public sector labs. Dr FitzGerald’s talk will describe her journey from neuroscience research to climate activism. \nThis seminar will take place online using the GoToMeeting platform
URL:https://ibecbarcelona.eu/event/phd-complementary-skills-session-lab-greening-how-you-can-play-your-part/
CATEGORIES:PhD Discussions Complementary Skills Session
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END:VCALENDAR