Institute for Bioengineering of Catalonia

IBEC Seminar: Francesco Ricci
2018-05-02 12:00 - 13:00 (Europe/Madrid) | IBEC, floor 11, Tower I, Baldiri Reixac 4-8, 08028 Barcelona, Spain
DNA-based nanodevices for diagnostic and drug-delivery applications
Francesco Ricci, Chemistry Department, University of Rome, Tor Vergata, Rome, Italy
DNA nanotechnology uses DNA (or nucleic acids) as a versatile material to rationally engineer tools and molecular devices that can find a multitude of different applications (e.g., in-vivo and in-vitro diagnostics, drug delivery, genetic circuits etc.).
During this presentation I will introduce the field of DNA nanotechnology and I will talk about some of the most exciting examples of the last decade.
I will show how to exploit the “designability” of DNA to fabricate nature-inspired DNA-based nanoswitches and nanodevices that are specifically designed to undergo a conformational change (switch) upon binding to a specific input (i.e. target). This input-triggered conformational change can be used for diagnostic, drug-delivery or synthetic-biology applications.
I will demonstrate how to characterize and recreate in-vitro several mechanisms to control the response of DNA-based nanodevices (1-2) and how to regulate their activity with different chemical and environmental stimuli including pH (3-8), antibodies (2-3), enzymes (9), small molecules (10) and electronic inputs (11).
References
[1] Porchetta. A., et al., J. Am. Chem. Soc., 2013, 135, 13238.
[2] Ranallo, S. et al., Angew. Chem., 2015, 54, 13214.
[3] Ranallo, S. et al., Nat. Commun., 2017, 8, 15150.
[4] Idili, A. et al., Nano Lett., 2015, 15, 5539.
[5] Porchetta, A, et al. Nano Lett., 2015, 15, 4467.
[6] Amodio, A. et al., J. Am. Chem. Soc., 2014, 136, 16469.
[7] Idili, A. et al., J. Am. Chem. Soc., 2014, 136, 5836.
[8] Mariottini, D. et al., Nano Lett., 2017, 17, 3225.
[9] Amodio, A. et al., J. Am. Chem. Soc., 2016, , 138, 12735.
[10] Del Grosso, E. et al., Nano Lett., 2015, 15, 8407.
[11] Ranallo, S. et al., Chem. Sc., 2016, 7, 66-71.

PhD thesis defence: Berta Gumí
2018-04-27 11:00 - 13:00 | Sala Antiga de Graus, Faculty of Physics, UB, Barcelona, 08028, Spain
“Structural organization of model membranes: a complementary approach combining atomic force microscopy and x-ray techniques”
Berta Gumí, Nanoprobes and Nanoswitches group
Berta will be defending her PhD thesis on Friday 27th April at 11:00 in the Sala Antiga de Graus, Faculty of Physics, University of Barcelona.
Everybody is welcome to attend.
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If you’re an IBEC PhD student and would like to advertise your PhD defence on the IBEC calendar, please contact vleigh@ibecbarcelona.eu

IBEC PhD Discussions Complementary Skills Session: Equity crowdfunding
2018-04-27 10:00 - 11:00 | IBEC, floor 11, Tower I, Baldiri Reixac 4-8, 08028 Barcelona, Spain
Equity crowdfunding to link entrepreneurs and investors in life sciences
Pilar Puig-Sàrries PhD, Head of the BioExpert Network & Lead Analyst at Capital Cell
Capital Cell is Europe’s first equity crowdfunding platform specialising in life sciences. From their offices in Cambridge and Barcelona they source innovative, early stage companies in biotech and healthcare from across Europe to help fund their growth. In this process, the contribution of experts in science and business is crucial to help filter the best investment opportunities. From her experience, Pilar Puig-Sàrries will talk about how we can get funding for our innovative projects through crowdfunding and how we can also become investors from as little as 100€.

SciDF@Bars: "Del Laboratorio al Parlamento: Asesoramiento Científico"
2018-04-26 19:00 - 21:30 | Mau Mau, 35 Calle de Fontrodona, 08004 Barcelona, Spain
Many political issues are related to science and technology: climate change, vaccines, ciber-security or the use of glyphosate are some examples of how science gets onto the politic agenda.
For all those issues scientific advice is needed: How does it work? Which different models exist? How is science advice organised in different regions of the world and, specially, in Spain and Catalunya?
In this SciDF@Bars, we will discuss with experts and perform a study case to talk about it while having some beers and networking with friends.
Join us next Thursday, 26th April at 19:15h in Mau Mau!
The entrance fee is 5€, with one beer included*. Event language: SPANISH
*The fee for the event helps to finance the activities of Scientists Dating Forum, whose complete spectrum of activities you can find on www.scientistsdatingforum.org.

IBEC Seminar: (David) Dagan Feng
2018-04-20 10:00 - 11:00 | IBEC, floor 11, Tower I, Baldiri Reixac 4-8, 08028 Barcelona, Spain
Biomedical Engineering and Technology Research at USYD and beyond
(David) Dagan Feng, PhD, FACS, FATSE, FHKIE, FIEEE, & FIET
Recent advances in engineering, information technology and imaging have revolutionized biotechnology, biomedical research and healthcare. This talk will initially focus on some of his core theories and enabling techniques research in molecular imaging for E-Healthcare and its impact to clinical practice, in particular in cancer and metabolic diseases. This talk will then give an overview of the Biomedical Engineering and Technology research at the University of Sydney and beyond, in particular several University new initiatives and the USYD-SJTU Joint Research Alliance.

International PhD Programme interviews
2018-04-18 08:00 - 2018-04-19 17:00 | PCB, Baldiri Reixa 4-8, 10-12, 15-21, Barcelona, Spain
In 2018, four fellowships will be funded by the Spanish Ministry of Economy, Industry and Competitiveness through the ‘Ayudas para contratos predoctorales para la formación de doctores’ 2018 call. Three additional fellowships will be funded by IBEC through the Severo Ochoa Excellence Award (IBEC Severo Ochoa Fellowship), Fundación Bancaria La Caixa and Fundación Cellex.
April 18th-19th 2018: Interviews in Barcelona with selection committee and group leaders responsible for research projects.
April 27th 2018: Publication of final list of selected candidates. Letter of acceptance to be signed by candidates.
May-October 2018: Start of the fellowships funded by Fundación Bancaria La Caixa and Fundación Cellex, to be agreed with the Group Leader responsible.
Beginning of 2019 (To be confirmed, based on the resolution of the call ‘Ayudas para contratos predoctorales para la formación de doctores’ by the Spanish Ministry of Economy, Industry and Competitivity): Start of the rest of the fellowships.
https://ibecbarcelona.eu/phd/IIPPfellowships

International PhD Programme interviews
2018-04-18 08:00 - 2018-04-19 17:00 | PCB, Baldiri Reixa 4-8, 10-12, 15-21, Barcelona, Spain
In 2018, four fellowships will be funded by the Spanish Ministry of Economy, Industry and Competitiveness through the ‘Ayudas para contratos predoctorales para la formación de doctores’ 2018 call. Three additional fellowships will be funded by IBEC through the Severo Ochoa Excellence Award (IBEC Severo Ochoa Fellowship), Fundación Bancaria La Caixa and Fundación Cellex.
April 18th-19th 2018: Interviews in Barcelona with selection committee and group leaders responsible for research projects.
April 27th 2018: Publication of final list of selected candidates. Letter of acceptance to be signed by candidates.
May-October 2018: Start of the fellowships funded by Fundación Bancaria La Caixa and Fundación Cellex, to be agreed with the Group Leader responsible.
Beginning of 2019 (To be confirmed, based on the resolution of the call ‘Ayudas para contratos predoctorales para la formación de doctores’ by the Spanish Ministry of Economy, Industry and Competitivity): Start of the rest of the fellowships.
http://ibecbarcelona.eu/phd/IIPPfellowships

IBEC Seminar: Joan Seoane
2018-04-13 10:00 - 11:00 | IBEC, floor 11, Tower I, Baldiri Reixac 4-8, 08028 Barcelona, Spain
Intratumor heterogeneity in brain cancer
Joan Seoane, Group Leader / Director of Translational Research at Vall d’Hebron Institute of Oncology (VHIO)
Joan Seoane is a Group Leader and Director of the Translational Research program at the Vall d’Hebron Institute of Oncology (VHIO) within the Vall d’Hebron University Hospital since 2011.
In 1998, Joan obtained his PhD in Biochemistry and Molecular Biology from the University of Barcelona. Previously, in 1993, he obtained his BSc degree in Chemistry. Joan joined the Memorial Sloan-Kettering Cancer Center (MSKCC) in New York as a post-doctoral fellow in 1998.
From 1998 to 2001, he worked as a Research Fellow and subsequently, from 2001 to 2003, as a Research Associate. He was appointed ICREA Research Professor in 2004 and joined VHIO.
In 2007, he became a member of the EMBO Young Investigator program and the recipient of a European Research Council (ERC) grant in 2008. Later, he obtained two ERC Proof of Concept grants (2011, 2013). In 2008, he became Board member of the European Association of Cancer Research (EACR) and Professor of the Autonomous University of Barcelona.
In 2012, founded Mosaic Biomedicals as a spin-off company from his lab and, in 2013, he was the recipient of the Dr. Josef Steiner Award. In 2016, he became Secretary General of the EACR.

hPSCs training course
2018-04-12 09:00 - 2018-04-13 15:00 | IBEC, Baldiri Reixac 10-12, Barcelona, 08028, Spain
Reprogramming, Differentiation and Molecular Genetics
This two-day course comprises lectures and practical hands-on workshops run by specialized trainers from academia and industry. The course will provide an overview of reprogramming techniques, molecular genetics (including CRISPR/Cas9 and hPSCs), differentiation, and organoid derivation. It will be of particular interest to PhD students and postdoctoral fellows aiming to work or already trained in the field of hPSCs.
Register: http://events.ibecbarcelona.eu/hPSCs-training-course/

Fira de Recerca en Directe 2018
2018-04-11 10:00 - 2018-04-14 15:00 | CosmoCaixa Barcelona, Carrer d'Isaac Newton, 08022 Barcelona, Spain
Posa’t a la pell d’un científic!
De l’11 al 14 d’abril i en el marc de la 16a edició de la Fira Recerca en Directe –organitzada pel Parc Científic de Barcelona i Obra Social “la Caixa”– més de 75 investigadors d’onze centres capdavanters de Catalunya traslladaran els seus laboratoris a CosmoCaixa Barcelona per convidar als ciutadans a participar en els seus projectes de recerca i resoldre enigmes tot seguint el mètode científic.
Enguany l’IBEC participa amb l’activitat: La mecànica cel·lular, la membrana de més a prop.

Els participants coneixeran com s’adapta la membrana cel·lular als estímuls del seu entorn acompanyats dels investigadors del grup de Mecanobiologia Cel·lular i Molecular i Dinàmica Integrativa de Cèl·lules i Teixits de l’IBEC.
La Xarxa Quiroga, el Carlos Pérez, l’Ariadna Marín i el Macià Esteve us explicaran quins són els mecanismes que utilitzen les cèl·lules per detectar i respondre a estímuls mecànics i com les forces i el control molecular cooperen per aconseguir que els teixits duguin a terme la seva funció biològica.
ACTIVITAT: 16a edició de la Fira Recerca en Directe
LLOC: CosmoCaixa Barcelona · Carrer d’Isaac Newton, 26 · 08022 Barcelona
DIES: Escoles: De l’11 al 13 d’abril (Entrada gratuïta prèvia reserva).
Públic general: Dissabte 14 d’abril (Visita inclosa amb l’entrada de CosmoCaixa Barcelona).
HORARI: De l’11 al 13 d’abril: de 10.00 h a 15.00 h
Dissabte 14 d’abril: de 10.00 h a 14.00 h / A les 12.00 h: Activitat conduïda per Francesc Orella (Protagonista de la sèrie Merlí).
Aforament limitat. Reserves: 934 031 134 / difusiociencia@pcb.ub.cat
