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DTSTART;TZID=Europe/Madrid:20190802T120000
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CREATED:20190730T070132Z
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UID:96491-1564747200-1564754400@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Kara Spiller
DESCRIPTION:Immunomodulatory Biomaterials for Limb Salvage\nKara Spiller\, School of Biomedical Engineering\, Science\, and Health Systems\, Drexel University \nDiabetes and peripheral arterial disease affect hundreds of millions of people worldwide. Patients with these conditions frequently develop chronic wounds on the lower limbs that lead to amputation\, with a 5-year mortality rate as high as 77%. Macrophages\, the primary cell of the innate immune system\, are critical regulators of angiogenesis and wound healing. Their dysfunction is strongly implicated in arterial dysfunction\, limb ischemia\, and poorly healing chronic wounds. The goal of the Biomaterials and Regenerative Medicine Laboratory at Drexel University is to understand the mechanisms by which macrophages orchestrate successful angiogenesis and tissue regeneration and to develop novel biomaterial strategies that apply these principles to pathological situations\, in order to ultimately prevent limb amputation. This talk will focus on the effects of temporal changes in macrophage phenotype on angiogenesis\, the design of biomaterials and drug delivery systems to modulate macrophage phenotype for enhanced angiogenesis\, and the development of macrophage phenotype-related biomarkers to assist in clinical decision making for a personalized medicine approach to wound care. \nDr. Kara Spiller is an Associate Professor in Drexel University’s School of Biomedical Engineering\, Science\, and Health Systems. Her research interests include the role of immune cells in tissue regeneration\, the design of immunomodulatory biomaterials\, and international engineering education. Her research is funded by the NIH\, the NSF\, and private foundations. Her awards include a Fulbright fellowship\, the NSF CAREER award\, and the United States nomination for the ASPIRE prize.
URL:https://ibecbarcelona.eu/event/ibec-seminar-kara-spiller-3/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20190802T120000
DTEND;TZID=Europe/Madrid:20190802T140000
DTSTAMP:20260503T183254
CREATED:20190730T070132Z
LAST-MODIFIED:20190730T070146Z
UID:67507-1564747200-1564754400@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Kara Spiller
DESCRIPTION:Immunomodulatory Biomaterials for Limb Salvage\nKara Spiller\, School of Biomedical Engineering\, Science\, and Health Systems\, Drexel University \nDiabetes and peripheral arterial disease affect hundreds of millions of people worldwide. Patients with these conditions frequently develop chronic wounds on the lower limbs that lead to amputation\, with a 5-year mortality rate as high as 77%. Macrophages\, the primary cell of the innate immune system\, are critical regulators of angiogenesis and wound healing. Their dysfunction is strongly implicated in arterial dysfunction\, limb ischemia\, and poorly healing chronic wounds. The goal of the Biomaterials and Regenerative Medicine Laboratory at Drexel University is to understand the mechanisms by which macrophages orchestrate successful angiogenesis and tissue regeneration and to develop novel biomaterial strategies that apply these principles to pathological situations\, in order to ultimately prevent limb amputation. This talk will focus on the effects of temporal changes in macrophage phenotype on angiogenesis\, the design of biomaterials and drug delivery systems to modulate macrophage phenotype for enhanced angiogenesis\, and the development of macrophage phenotype-related biomarkers to assist in clinical decision making for a personalized medicine approach to wound care. \nDr. Kara Spiller is an Associate Professor in Drexel University’s School of Biomedical Engineering\, Science\, and Health Systems. Her research interests include the role of immune cells in tissue regeneration\, the design of immunomodulatory biomaterials\, and international engineering education. Her research is funded by the NIH\, the NSF\, and private foundations. Her awards include a Fulbright fellowship\, the NSF CAREER award\, and the United States nomination for the ASPIRE prize.
URL:https://ibecbarcelona.eu/event/ibec-seminar-kara-spiller/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20190802T120000
DTEND;TZID=Europe/Madrid:20190802T140000
DTSTAMP:20260503T183254
CREATED:20190730T070132Z
LAST-MODIFIED:20190730T070132Z
UID:96490-1564747200-1564754400@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Kara Spiller
DESCRIPTION:Immunomodulatory Biomaterials for Limb Salvage\nKara Spiller\, School of Biomedical Engineering\, Science\, and Health Systems\, Drexel University \nDiabetes and peripheral arterial disease affect hundreds of millions of people worldwide. Patients with these conditions frequently develop chronic wounds on the lower limbs that lead to amputation\, with a 5-year mortality rate as high as 77%. Macrophages\, the primary cell of the innate immune system\, are critical regulators of angiogenesis and wound healing. Their dysfunction is strongly implicated in arterial dysfunction\, limb ischemia\, and poorly healing chronic wounds. The goal of the Biomaterials and Regenerative Medicine Laboratory at Drexel University is to understand the mechanisms by which macrophages orchestrate successful angiogenesis and tissue regeneration and to develop novel biomaterial strategies that apply these principles to pathological situations\, in order to ultimately prevent limb amputation. This talk will focus on the effects of temporal changes in macrophage phenotype on angiogenesis\, the design of biomaterials and drug delivery systems to modulate macrophage phenotype for enhanced angiogenesis\, and the development of macrophage phenotype-related biomarkers to assist in clinical decision making for a personalized medicine approach to wound care. \nDr. Kara Spiller is an Associate Professor in Drexel University’s School of Biomedical Engineering\, Science\, and Health Systems. Her research interests include the role of immune cells in tissue regeneration\, the design of immunomodulatory biomaterials\, and international engineering education. Her research is funded by the NIH\, the NSF\, and private foundations. Her awards include a Fulbright fellowship\, the NSF CAREER award\, and the United States nomination for the ASPIRE prize.
URL:https://ibecbarcelona.eu/event/ibec-seminar-kara-spiller-2/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20190802T120000
DTEND;TZID=Europe/Madrid:20190802T140000
DTSTAMP:20260503T183254
CREATED:20190730T070132Z
LAST-MODIFIED:20190730T070132Z
UID:96492-1564747200-1564754400@ibecbarcelona.eu
SUMMARY:IBEC Seminar: Kara Spiller
DESCRIPTION:Immunomodulatory Biomaterials for Limb Salvage\nKara Spiller\, School of Biomedical Engineering\, Science\, and Health Systems\, Drexel University \nDiabetes and peripheral arterial disease affect hundreds of millions of people worldwide. Patients with these conditions frequently develop chronic wounds on the lower limbs that lead to amputation\, with a 5-year mortality rate as high as 77%. Macrophages\, the primary cell of the innate immune system\, are critical regulators of angiogenesis and wound healing. Their dysfunction is strongly implicated in arterial dysfunction\, limb ischemia\, and poorly healing chronic wounds. The goal of the Biomaterials and Regenerative Medicine Laboratory at Drexel University is to understand the mechanisms by which macrophages orchestrate successful angiogenesis and tissue regeneration and to develop novel biomaterial strategies that apply these principles to pathological situations\, in order to ultimately prevent limb amputation. This talk will focus on the effects of temporal changes in macrophage phenotype on angiogenesis\, the design of biomaterials and drug delivery systems to modulate macrophage phenotype for enhanced angiogenesis\, and the development of macrophage phenotype-related biomarkers to assist in clinical decision making for a personalized medicine approach to wound care. \nDr. Kara Spiller is an Associate Professor in Drexel University’s School of Biomedical Engineering\, Science\, and Health Systems. Her research interests include the role of immune cells in tissue regeneration\, the design of immunomodulatory biomaterials\, and international engineering education. Her research is funded by the NIH\, the NSF\, and private foundations. Her awards include a Fulbright fellowship\, the NSF CAREER award\, and the United States nomination for the ASPIRE prize.
URL:https://ibecbarcelona.eu/event/ibec-seminar-kara-spiller-4/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:IBEC Seminar
END:VEVENT
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