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X-WR-CALDESC:Events for Institute for Bioengineering of Catalonia
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DTSTART;TZID=Europe/Madrid:20220201T100000
DTEND;TZID=Europe/Madrid:20220201T120000
DTSTAMP:20260501T003749
CREATED:20220427T085100Z
LAST-MODIFIED:20220427T085101Z
UID:93896-1643709600-1643716800@ibecbarcelona.eu
SUMMARY:PhD Thesis Defence: Lucía Selfa Aspiroz
DESCRIPTION:Engineering human pluripotent stem cells to understand kidney development and disease\n\n\n\nLucía Selfa Aspiroz\, Pluripotency for organ regeneration group \n\n\n\nThis thesis defence will start at 10AM. If you wisth to attend to this PhD thesis defence\, you can join here via zoom.
URL:https://ibecbarcelona.eu/event/phd-thesis-defence-lucia-selfa-aspiroz/
CATEGORIES:PhD Thesis Defence
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220204T100000
DTEND;TZID=Europe/Madrid:20220204T130000
DTSTAMP:20260501T003749
CREATED:20220427T085707Z
LAST-MODIFIED:20220427T085709Z
UID:93899-1643968800-1643979600@ibecbarcelona.eu
SUMMARY:Nanodía mundial contra el cáncer – 2022
DESCRIPTION:El Nanodía Mundial Contra el Cáncer es un evento organizado en el marco del Día Mundial contra el Cáncer donde se darán a conocer las últimas innovaciones en materia de NANOMEDICINA contra el CÁNCER\, con temas que van desde el diagnóstico precoz\, la liberación controlada de fármacos o la radioterapia con nanopartículas. \n\n\n\nUn año más\, expertos en NANOMEDICINA de diferentes campos -investigadores\, empresarios\, médicos oncólogos\, pacientes\, etc.-\,  expondrán los últimos avances y nos darán la oportunidad de descubrir el generador de progreso que la NANOMEDICINA significa para la salud como creador de nuevas oportunidades en el diagnóstico y el tratamiento del cáncer y como podemos contribuir en la misión Europea contra el cáncer. \n\n\n\nIniciado bajo el nombre de NANO WORLD CANCER DAY\, NANOMED Spain organiza la edición de este año de manera virtual con la colaboración del VHIR (Vall d’Hebron Instituto de Investigación) y el VHIO (Vall d’Hebron Instituto de Oncología).  \n\n\n\nMás información y registro aquí.
URL:https://ibecbarcelona.eu/event/nanodia-mundial-contra-el-cancer-2022/
CATEGORIES:Joint seminar / workshop / symposium
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220225T100000
DTEND;TZID=Europe/Madrid:20220225T170000
DTSTAMP:20260501T003749
CREATED:20220218T094610Z
LAST-MODIFIED:20220218T094610Z
UID:96527-1645783200-1645808400@ibecbarcelona.eu
SUMMARY:PhD Discussions: Giulia Fornabaio and Shubham Tanwar
DESCRIPTION:Biomechanics of the progression of colorectal carcinomas\nGiulia Fornabaio\, Synthetic morphogenesis group \nAccording to the World Health Organization\, cancer is one of the main causes of death worldwide\, with colorectal carcinoma (CRC) being the second-leading cause of tumour related-death. The high rate of mortality of CRCs is principally attributed to the metastasis of neoplastic cells from the primary tumour to secondary organs such as the liver\, the lung and the peritoneum. These cells can disseminate either as single isolated cells or as collective clusters\, undergoing a series of molecular and cellular changes commonly known as Epithelial to Mesenchymal Transition (EMT). However\, in 2018\, Jaulin and her team described a novel modality of peritoneal metastatic spread characterized by the presence of large clusters of cancer cells\, which maintain their epithelial properties and display an outward apical polarity. These clusters of cells\, termed tumour spheres with inverted polarity (TSIPs)\, were found in peritoneal effusions of CRCs patients showing early KRAS mutation and hypermethylation of CpG Islands. \nTSIPs originate through a series of morphological changes: the first event is the sprouting of hypermethylated epithelia\, followed by their apical budding\, leading to the formation of rounded spherical clusters of cells called buds\, and the subsequent cleavage of the newly formed spheres. How cell and tissue mechanics drive this process is still unclear. To provide novel insights into this metastatic cascade\, our project aims at deciphering the biomechanical and cellular events regulating the formation of buds in colorectal cancer cell lines. Employing a combination between cellular biology techniques with biophysical methods\, we showed that this process is characterized by over-proliferation and local changes in cell adhesion\, coupled with the formation of cellular vortexes surrounding the buds. Our study demonstrates that buds development in colorectal carcinomas epithelia is governed by morphological transitions occurring entirely at multicellular level\, rather than by single cells aggregation or cell extrusion. \nImaging Functional Organic Bioelectronic Platforms at the Nanoscale\nShubham Tanwar\, Nanoscale Bioelectrical Characterization group \nIn recent years\, many organic bioelectronic platforms have emerged to bridge the signaling gap between biology and technology. Organic bioelectronic platforms based on transistor architecture\, commonly known as Electrolyte-Gated Transistors (EGTs)\, are an excellent tool to selectively sense\, record\, and monitor biological signals and states\, and convert them into measurable electrical signals.1 Biological events happening at the nanoscale are now routinely studied and characterized by a millimeter-sized transistor. However\, it is not well understood how these nanoscale events interact with the transistor’s nanoscale properties leading to a change in their macroscale response. This gap in understanding is purely due to the lack of techniques to image the electrical properties in a liquid environment. Towards this goal\, our group has adapted in-Liquid Scanning Dielectric Microscopy to unravel the inner working of EGTs at the nanoscale.2 Besides apparent topographical changes\, electrical properties\, like conductivity and interfacial capacitance\, and mechanical properties are mapped at the nanoscale in a working transistor in liquid. The vast information extracted has made it possible to correlate the nanoscale processes with the macroscale response\, offering improved understanding and the potential for substantial optimization of bioelectronic devices. \nThis PhD Discussion session will be held at Tower I\, 11th floor Baobab room\, there will be 30 avialable seats\, the free spots will be assigned on a first come first served basis.
URL:https://ibecbarcelona.eu/event/phd-discussions-giulia-fornabaio-and-shubham-tanwar-2/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220225T100000
DTEND;TZID=Europe/Madrid:20220225T170000
DTSTAMP:20260501T003749
CREATED:20220218T094610Z
LAST-MODIFIED:20220218T094610Z
UID:90539-1645783200-1645808400@ibecbarcelona.eu
SUMMARY:PhD Discussions: Giulia Fornabaio and Shubham Tanwar
DESCRIPTION:Biomechanics of the progression of colorectal carcinomas\nGiulia Fornabaio\, Synthetic morphogenesis group \nAccording to the World Health Organization\, cancer is one of the main causes of death worldwide\, with colorectal carcinoma (CRC) being the second-leading cause of tumour related-death. The high rate of mortality of CRCs is principally attributed to the metastasis of neoplastic cells from the primary tumour to secondary organs such as the liver\, the lung and the peritoneum. These cells can disseminate either as single isolated cells or as collective clusters\, undergoing a series of molecular and cellular changes commonly known as Epithelial to Mesenchymal Transition (EMT). However\, in 2018\, Jaulin and her team described a novel modality of peritoneal metastatic spread characterized by the presence of large clusters of cancer cells\, which maintain their epithelial properties and display an outward apical polarity. These clusters of cells\, termed tumour spheres with inverted polarity (TSIPs)\, were found in peritoneal effusions of CRCs patients showing early KRAS mutation and hypermethylation of CpG Islands. \nTSIPs originate through a series of morphological changes: the first event is the sprouting of hypermethylated epithelia\, followed by their apical budding\, leading to the formation of rounded spherical clusters of cells called buds\, and the subsequent cleavage of the newly formed spheres. How cell and tissue mechanics drive this process is still unclear. To provide novel insights into this metastatic cascade\, our project aims at deciphering the biomechanical and cellular events regulating the formation of buds in colorectal cancer cell lines. Employing a combination between cellular biology techniques with biophysical methods\, we showed that this process is characterized by over-proliferation and local changes in cell adhesion\, coupled with the formation of cellular vortexes surrounding the buds. Our study demonstrates that buds development in colorectal carcinomas epithelia is governed by morphological transitions occurring entirely at multicellular level\, rather than by single cells aggregation or cell extrusion. \nImaging Functional Organic Bioelectronic Platforms at the Nanoscale\nShubham Tanwar\, Nanoscale Bioelectrical Characterization group \nIn recent years\, many organic bioelectronic platforms have emerged to bridge the signaling gap between biology and technology. Organic bioelectronic platforms based on transistor architecture\, commonly known as Electrolyte-Gated Transistors (EGTs)\, are an excellent tool to selectively sense\, record\, and monitor biological signals and states\, and convert them into measurable electrical signals.1 Biological events happening at the nanoscale are now routinely studied and characterized by a millimeter-sized transistor. However\, it is not well understood how these nanoscale events interact with the transistor’s nanoscale properties leading to a change in their macroscale response. This gap in understanding is purely due to the lack of techniques to image the electrical properties in a liquid environment. Towards this goal\, our group has adapted in-Liquid Scanning Dielectric Microscopy to unravel the inner working of EGTs at the nanoscale.2 Besides apparent topographical changes\, electrical properties\, like conductivity and interfacial capacitance\, and mechanical properties are mapped at the nanoscale in a working transistor in liquid. The vast information extracted has made it possible to correlate the nanoscale processes with the macroscale response\, offering improved understanding and the potential for substantial optimization of bioelectronic devices. \nThis PhD Discussion session will be held at Tower I\, 11th floor Baobab room\, there will be 30 avialable seats\, the free spots will be assigned on a first come first served basis.
URL:https://ibecbarcelona.eu/event/phd-discussions-giulia-fornabaio-and-shubham-tanwar-2/
LOCATION:IBEC\, floor 11\, Tower I\, Baldiri Reixac 4-8\, 08028 Barcelona\, Spain
CATEGORIES:IBEC Seminar
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220225T100000
DTEND;TZID=Europe/Madrid:20220225T170000
DTSTAMP:20260501T003749
CREATED:20220427T110714Z
LAST-MODIFIED:20220503T142126Z
UID:93902-1645783200-1645808400@ibecbarcelona.eu
SUMMARY:PhD Discussions: Giulia Fornabaio and Shubham Tanwar
DESCRIPTION:Biomechanics of the progression of colorectal carcinomas\n\n\n\nGiulia Fornabaio\, Synthetic morphogenesis group \n\n\n\nAccording to the World Health Organization\, cancer is one of the main causes of death worldwide\, with colorectal carcinoma (CRC) being the second-leading cause of tumour related-death. The high rate of mortality of CRCs is principally attributed to the metastasis of neoplastic cells from the primary tumour to secondary organs such as the liver\, the lung and the peritoneum. These cells can disseminate either as single isolated cells or as collective clusters\, undergoing a series of molecular and cellular changes commonly known as Epithelial to Mesenchymal Transition (EMT). However\, in 2018\, Jaulin and her team described a novel modality of peritoneal metastatic spread characterized by the presence of large clusters of cancer cells\, which maintain their epithelial properties and display an outward apical polarity. These clusters of cells\, termed tumour spheres with inverted polarity (TSIPs)\, were found in peritoneal effusions of CRCs patients showing early KRAS mutation and hypermethylation of CpG Islands. \n\n\n\nTSIPs originate through a series of morphological changes: the first event is the sprouting of hypermethylated epithelia\, followed by their apical budding\, leading to the formation of rounded spherical clusters of cells called buds\, and the subsequent cleavage of the newly formed spheres. How cell and tissue mechanics drive this process is still unclear. To provide novel insights into this metastatic cascade\, our project aims at deciphering the biomechanical and cellular events regulating the formation of buds in colorectal cancer cell lines. Employing a combination between cellular biology techniques with biophysical methods\, we showed that this process is characterized by over-proliferation and local changes in cell adhesion\, coupled with the formation of cellular vortexes surrounding the buds. Our study demonstrates that buds development in colorectal carcinomas epithelia is governed by morphological transitions occurring entirely at multicellular level\, rather than by single cells aggregation or cell extrusion. \n\n\n\nImaging Functional Organic Bioelectronic Platforms at the Nanoscale\n\n\n\nShubham Tanwar\, Nanoscale Bioelectrical Characterization group \n\n\n\nIn recent years\, many organic bioelectronic platforms have emerged to bridge the signaling gap between biology and technology. Organic bioelectronic platforms based on transistor architecture\, commonly known as Electrolyte-Gated Transistors (EGTs)\, are an excellent tool to selectively sense\, record\, and monitor biological signals and states\, and convert them into measurable electrical signals.1 Biological events happening at the nanoscale are now routinely studied and characterized by a millimeter-sized transistor. However\, it is not well understood how these nanoscale events interact with the transistor’s nanoscale properties leading to a change in their macroscale response. This gap in understanding is purely due to the lack of techniques to image the electrical properties in a liquid environment. Towards this goal\, our group has adapted in-Liquid Scanning Dielectric Microscopy to unravel the inner working of EGTs at the nanoscale.2 Besides apparent topographical changes\, electrical properties\, like conductivity and interfacial capacitance\, and mechanical properties are mapped at the nanoscale in a working transistor in liquid. The vast information extracted has made it possible to correlate the nanoscale processes with the macroscale response\, offering improved understanding and the potential for substantial optimization of bioelectronic devices. \n\n\n\nThis PhD Discussion session will be held at Tower I\, 11th floor Baobab room\, there will be 30 avialable seats\, the free spots will be assigned on a first come first served basis.
URL:https://ibecbarcelona.eu/event/phd-discussions-giulia-fornabaio-and-shubham-tanwar/
LOCATION:IBEC\, floor 11\, Tower i\, Baldiri Reixac 4-8\, Barcelona\, 08028\, Spain
CATEGORIES:PhD Discussions Session
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20220228T000000
DTEND;TZID=Europe/Madrid:20220228T130000
DTSTAMP:20260501T003749
CREATED:20220429T070900Z
LAST-MODIFIED:20220429T070901Z
UID:93910-1646006400-1646053200@ibecbarcelona.eu
SUMMARY:Nano Rare Diseases Day 2022
DESCRIPTION:Nano Rare Diseases Day es un evento organizado en el marco del Día Mundial de las Enfermedades Minoritarias donde se darán a conocer las últimas innovaciones en materia de Nanomedicina con temas que van desde el diagnóstico precoz\, la liberación controlada de fármacos o el desarrollo de nuevas terapias. \n\n\n\nDurante esta jornada\, expertos en Nanomedicina de diferentes campos -investigación\, empresa\, práctica clínica\, autoridades sanitarias\, pacientes\, etc.-\,  expondrán los últimos avances y nos darán la oportunidad de descubrir el generador de progreso que la Nanomedicina significa para la salud como creador de nuevas oportunidades en el diagnóstico y el tratamiento de las enfermedades minoritarias. \n\n\n\nRegistro a la jornada online\, aquí
URL:https://ibecbarcelona.eu/event/nano-rare-diseases-day-2022/
CATEGORIES:Joint seminar / workshop / symposium
END:VEVENT
END:VCALENDAR