Breaking Paradigms: Delivering insulin orally Ester Caffarel, MIT Biologics have revolutionized disease treatment; however, their rapid degradation and poor absorption in the gastrointestinal (GI) tract generally limit their administration to parenteral routes. Devices for the oral delivery of biologics must aid in both localization and permeation to achieve systemic drug uptake. For this purpose, we ... Read more

Membraneless compartments based on intrinsically disordered proteins: from biology towards new protein materials Paolo Arosio, Institute for Chemical and Bioengineering, ETH Zurich In the last few years, discoveries in biology are revealing that a class of intrinsically disordered protein sequences plays an important role in the formation of cellular membraneless compartments by spontaneous liquid-liquid phase ... Read more

Diabetes, where are we? Anna Novials, PI of the group “Pathogenesis and Prevention of Diabetes” at IDIBAPS/Clinic Hospital of Barcelona and member of CIBERDEM network. Diabetes mellitus (DM) is a group of chronic metabolic disorders all characterized by hyperglycemia. It occurs either when the pancreas does not produce enough insulin or when the peripheral tissues ... Read more