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DTSTART;TZID=Europe/Madrid:20250613T100000
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DTSTAMP:20260418T041250
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SUMMARY:IBEC Seminar. Prof. Brendan Kennedy
DESCRIPTION:Optical coherence elastography: imaging cell and tissue mechanics on the micro-scale\nProfessor Brendan Kennedy. Department of Electrical\, Electronic and Computer Engineering\, School of Engineering\, The University of Western Australia. Group Leader\, BRITElab\, Harry Perkins Institute of Medical Research\, Western Australia. Institute of Physics\, Nicolaus Copernicus University in Torun\, Poland \nAbstract: As the importance of mechanical properties in the origin and progression of disease becomes ever clearer\, new elastography tools are required to map cell and tissue mechanics on the micro-scale. Elastography has been developed over a wide range of spatial scales\, from the cellular\, for example\, using atomic force microscopy\, through to the whole organ\, using ultrasound elastography and magnetic resonance elastography. However\, existing techniques are not capable of probing tissue mechanical properties on the intermediate micro- to milli-scale: a scale critical in the onset and progression of many diseases. Optical coherence elastography (OCE) aims to bridge the scale gap in elastography techniques. Through the utilization of optical coherence tomography (OCT) to measure tissue motion\, OCE is endowed with spatial resolution as high as 1-10 mm\, much higher than is possible using ultrasound or magnetic resonance imaging\, and a sensitivity to tissue displacement on the nanometer-scale\, providing the prospect to detect much finer changes in mechanical properties. \nIn this talk\, I will describe methods we have developed at The University of Western Australia and Nicolaus Copernicus University to quantify tissue elasticity\, ranging from mechanical loading methods to signal processing techniques to map the full strain tensor. I will focus on main two application areas. Firstly\, the application of OCE to tumour margin assessment in breast cancer\, where we have developed both ex vivo and in vivo OCE methods to detect tumour during surgery to enable surgeons to more accurately remove cancer. Secondly\, in mechanobiology\, I will describe the development of optical coherence microscopy-based elastography for imaging sub-cellular mechanics in three dimensions. I will describe a study we performed on tumour cell spheroids that reveals distinct stiffness in non-metastatic and metastatic spheroids embedded in both soft and stiff hydrogels. \nShort Bio: Prof. Brendan Kennedy is Professor in the School of Engineering at The University of Western Australia (UWA) and is Head of BRITElab at the Harry Perkins Institute of Medical Research\, also in Western Australia. He is currently Visiting Professor in the Institute of Physics at Nicolaus Copernicus University in Torun\, Poland. Prof. Kennedy received his PhD from Dublin City University\, Ireland\, in 2006. His doctoral thesis focussed on the use of nonlinear polarization rotation in semiconductor optical amplifiers for all-optical switching. His current research focusses on the development of optical coherence tomography and optical elastography and their application in a range of fields\, particularly in surgery\, mechanobiology and tissue engineering. He has published 1 book\, 15 book chapters and >100 peer-reviewed journal papers. Prof. Kennedy has delivered >30 invited talks at national and international conferences. He has been Principal Investigator on competitive research funding of >€12 million and industry-sponsored research contracts of >€3 million.  His work has been cited >8\,000 times and he has a H-index of 39 (source: Google Scholar). He has won a number of awards and recognitions\, including being elected as Optica Fellow in 2025. Prof. Kennedy is co-founder of OncoRes Medical\, a medical device company developing OCE for use in surgery. He served as Chief Scientific Officer at OncoRes from 2017 to 2021. OncoRes has received >€30 million in venture capital funding and currently employs >40 people. In 2021\, the company received the breakthrough designation from the US Food and Drugs Administration. Prof. Kennedy holds >40 granted patents from 8 patent families.
URL:https://ibecbarcelona.eu/es/event/ibec-seminar-prof-brendan-kennedy/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:IBEC Seminar
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DTSTART;TZID=Europe/Madrid:20250626T123000
DTEND;TZID=Europe/Madrid:20250626T133000
DTSTAMP:20260418T041250
CREATED:20250612T131516Z
LAST-MODIFIED:20250612T131603Z
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SUMMARY:Ibec Seminar. Dr. Maribel Vazquez
DESCRIPTION:Microfluidic Modeling of Aging Retina\nDr. Maribel Vazquez\,\, Professor of Biomedical Engineering Rutgers\, The State University of New Jersey. https://vazlab.org \nThe dramatic rise of chronic and age-related eye diseases is expected to increase the number of adults with vision loss by 50% in the next decade. Health Disparities with age\, sex\, and geography will further exacerbate impacts of vision loss worldwide. The retinal neurovascular unit plays critical roles in preserving vision from dysfunction caused by common diseases of diabetic retinopathy\, age-related macular degeneration\, and glaucoma. Our group has developed micro-physiological systems to examine cellular and molecular dysfunction across blood retinal barriers produced by food-derived\, advanced glycation end-products (AGEs) in circulating blood. Current projects measure changes in the permeability and resistivity of diabetic retinal barriers\, evaluate the use of electric fields to replace photoreceptors in the macula\, and examine newfound roles of glia in mediating retinal integrity within age-related and chronic\, pathological environments. Results highlight the role of microfluidics-based systems in identifying mechanisms of neurovascular response and evaluating effectiveness of pharmacology at different stages of disease. The laboratory also highlights the blending of Health Disparities in the development of biomedical therapies and training of biomedical engineers. \nDr. Vazquez is a Professor of Biomedical Engineering at Rutgers\, The State University of New Jersey. She began her career in industry at Intel Corporation and then completed a Doctor of Science in Mechanical Engineering at the Massachusetts Institute of Technology (MIT). She is an inducted Fellow of the American Institute of Medical and Biological Engineers (AIMBE) and Biomedical Engineering Society (BMES) for the contributions of microfluidic systems in the visual system. She received the 2023 AIMBE Professional Impact Award for the inclusion of Health Disparities within under/graduate training and was honored as the 2024 Plenary Speaker to the BMES Council of Chairs for integration of health disparities in Biomedical Engineering. She is an invited speaker in the special session of Retinal Engineering at the 2025 Tissue Engineering and Regenerative Medicine International Society (TERMIS).
URL:https://ibecbarcelona.eu/es/event/ibec-seminar-dr-maribel-vazquez/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:IBEC Seminar
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DTSTART;TZID=Europe/Madrid:20250627T093000
DTEND;TZID=Europe/Madrid:20250627T163000
DTSTAMP:20260418T041250
CREATED:20250610T102050Z
LAST-MODIFIED:20250611T072243Z
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SUMMARY:NET-AI. Workshop 3: "Deep learning for biomedical applications: fundamentals\, trustworthiness and explainability"
DESCRIPTION:This third workshop will focus on Deep Learning. It will start with an introductory session where the fundamental concepts of the subject will be presented\, which will then be put into practice during a hands-on activity focused on biomedical imaging. Then\, two more sessions with international speakers will address critical issues such as trustworthiness and explainability of these models\, two crucial aspects in the biomedical field.  \nSchedule programme:   \n9:40 – Registration   \n9:50 – Welcome from Network Coordinator  \n10:00 – Invited national speaker: Petia Radeva\, University of Barcelona (UB)\, “Deep learning – why everybody talks about it?»  \n11:00 – Coffee break  \n11:30 – Invited national speaker: Roser Sala-Llonch\, University of Barcelona\, “Deep Learning in Biomedical Imaging: Hands-on with Neural Networks and CNNs”  Practical activity – own computer required \n13:30 –  Lunch   \n14:15 – Invited international speaker: Lorin Werthen-Brabants\, Ghent University\,  “Trustworthy and Reliable (Deep) Machine Learning for Healthcare”  \n15:15 – Invited international speaker: Aray Karjauv\, University of Berlin\, “Explainability Beyond Labels: Why We Need XAI for Self-Supervised Learning”  \n16:15 – Final remarks and closing  \nTo registres click here \n 
URL:https://ibecbarcelona.eu/es/event/net-ai-workshop-3-deep-learning-for-biomedical-applications-fundamentals-trustworthiness-and-explainability/
LOCATION:Sala Dolors Aleu\, Cluster II\, IBEC\, Baldiri i Reixac\, Barcelona
CATEGORIES:IBEC Seminar
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