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DTSTART;VALUE=DATE:20201031
DTEND;VALUE=DATE:20201108
DTSTAMP:20260506T011752
CREATED:20201015T093105Z
LAST-MODIFIED:20201015T093524Z
UID:78235-1604102400-1604793599@ibecbarcelona.eu
SUMMARY:3rd EIT Health Innovation Day
DESCRIPTION:EIT Health Innovation Day\n \nIBEC is participating\, once more\, in the organization of this year’s EIT Health Innovation Day that will be held on-line from 31st October to 7th November 2020 (Dedication per day: 30-45 min. aprox. (flexible schedule)). \nInnovation Days (i-Days) promote health innovation among university students through dozens of one-to-two-day programmes held at academic institutions around Europe. Students receive an introduction to practical health innovation tools and compete in multidisciplinary teams to tackle real-life health challenges posed by EIT Health projects\, local organisations and private corporations. \ni-Day Barcelona will invite inspirational speakers and experts within the field of health innovation. Participants will form multidisciplinary teams to develop real and viable innovations\, compete for i-Day prizes and learn practical skills in innovation. The team with the most sparkling solution will participate in the European Winners event. At the Winners event\, participants will meet fellow EIT Health Innovation Day winners from universities across Europe\, and will further develop their ideas with the support from experienced business developers. \n\nThe i-Day is open to undergraduate and postgraduate students. \nWe invite you to  register here. Registrations will be open until October 26th. \nThe best projects of the day will be candidates for 4 prizes. \nYou can also see the calendar of i-Day events.
URL:https://ibecbarcelona.eu/es/event/3rd-eit-health-innovation-day/
CATEGORIES:Joint seminar / workshop / symposium
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20201109T150000
DTEND;TZID=Europe/Madrid:20201109T170000
DTSTAMP:20260506T011752
CREATED:20201104T112844Z
LAST-MODIFIED:20201104T112904Z
UID:78885-1604934000-1604941200@ibecbarcelona.eu
SUMMARY:PhD Thesis Defense: Dolores Blanco
DESCRIPTION:Noninvasive multimodal analysis of thoracic bioimpedance and myographic signals for the assessment of chronic obstructive pulmonary disease\nDolores Blanco\, Biomedical Signal Processing and Interpretation \nChronic respiratory diseases cause morbidity and premature mortality in adult population. In particular\, chronic obstructive pulmonary disease (COPD) represents a socioeconomic burden worldwide. COPD is usually evaluated by a spirometry test to quantify the airflow limitation. Classical spirometry requires the patients to move to the medical centers making difficult the continuous monitoring. Alternatively\, other noninvasive methods have been studied to monitor respiration because of their capability to provide valuable respiratory-related information. These techniques would lighten the intrusiveness of the measurements and ease the ambulatory monitoring of respiration. However\, the applicability of these methods into the clinics is still limited because of the lack of evidence in these applications. \nThe objective of this thesis is to propose and evaluate novel noninvasive methods to monitor respiration and assess obstructive diseases. We proposed a setup and a protocol to evaluate the applicability of thoracic bioimpedance and surface myographic signals for respiration assessment in healthy subjects and COPD patients. We acquired bioimpedance\, airflow and surface myographic signals in ten healthy subjects and fifty COPD patients. The physiological data was measured during an inspiratory threshold loading protocol to evaluate the methods during restrictive conditions. The thesis consisted of three different studies published in high impact factor journals. The two first studies delved into the changes of thoracic bioimpedance during restrictive breathing and\, the third one focused on the combination of bioimpedance and myographic signals for the assessment of COPD. \nPrevious studies showed a linear relationship between thoracic bioimpedance and respiratory volume during normal breathing. Firstly\, we assessed this linear relationship in healthy subjects for the first time\, during a loading protocol. We found a strong correlation between the signals even during highest loads. Nevertheless\, bioimpedance measurement is the combination of the different impedances of body tissues\, organs and fluids and consequently\, not only volume contributes to its measurement. Accordingly\, our second study aimed to evaluate the relevance of volume and chest movement to bioimpedance measurement at different levels of inspiratory muscle activity. We characterized bioimpedance using chest movement and volume signals by linear models and neural networks for different muscle effort. The results agreed with our previous results\, indicating that respiratory volume was the main contribution to bioimpedance\, but chest movement contributed substantially and more notably at high muscle activity. Both studies provided better knowledge of thoracic bioimpedance measurements which reinforces its use for noninvasive respiratory monitoring. \nFinally\, we evaluated the combination of thoracic bioimpedance and surface myographic signals in the COPD population. We proposed two novel ratios derived from the bioimpedance amplitude and myographic activity. These ratios showed significant differences between the mild and severe COPD patients meaning that the severest patients had lower inspiratory ventilation contribution of the inspiratory muscles. Consequently\, we suggest these novel ratios to provide valuable information to noninvasively monitor and complement the classical assessment of COPD. \nThe multimodal approach proposed in this thesis supports the application of thoracic bioimpedance for respiratory monitoring during normal and restrictive breathing. Furthermore\, the combination of bioimpedance and myographic information exhibited differences between COPD severity. The proposed methods will provide additional information about COPD condition which will be easily tracked by a single wearable device. Consequently\, the results of this thesis open up the way for a high-quality noninvasive monitoring of chronic respiratory patients. \n\nThis thesis defense will take place on Monday\, 9th November\, at 15:00 hours. \nLocation: The defense will be online using Microsoft Teams. People are invited to attend upon receiving a link that you have to request to Dolores Blanco (dblanco@ibecbarcelona.eu) or Raimon Jané (rjane@ibecbarcelona.eu).
URL:https://ibecbarcelona.eu/es/event/phd-thesis-defense-dolores-blanco/
CATEGORIES:PhD Thesis Defence
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20201113T100000
DTEND;TZID=Europe/Madrid:20201113T120000
DTSTAMP:20260506T011752
CREATED:20201030T121221Z
LAST-MODIFIED:20201110T121252Z
UID:78777-1605261600-1605268800@ibecbarcelona.eu
SUMMARY:Online IBEC Seminar: Xavier Trepat
DESCRIPTION:Mechanobiology of intestinal organoids\n \nXavier Trepat\, IBEC \nIntestinal organoids capture essential features of the intestinal epithelium such as folding of the crypt\, spatial compartmentalization of different cell types\, and cellular movements from crypt to villus-like domains. Each of these processes and their coordination in time and space requires patterned physical forces that are currently unknown. In this study\, we map the three-dimensional cell-ECM and cell-cell forces in mouse intestinal organoids grown on soft hydrogels. We show that these organoids exhibit a non-monotonic stress distribution that defines mechanical and functional compartments. The stem cell compartment pushes the ECM and folds through apical constriction\, whereas the transit amplifying zone pulls the ECM and elongates through basal constriction. Tension measurements establish that the transit amplifying zone isolates mechanically the stem cell compartment and the villus-like domain. A 3D vertex model shows that the shape and force distribution of the crypt can be largely explained by cell surface tensions following the measured apical and basal actomyosin density. Finally\, we show that cells are pulled out of the crypt along a gradient of increasing tension\, rather than pushed by a compressive stress downstream of mitotic pressure as previously assumed. Our study unveils how patterned forces enable folding and collective migration in the intestinal crypt. \nThis seminar will take place online at the Microsoft Teams Platform \nKnow more about Xavier Trepat’s research here
URL:https://ibecbarcelona.eu/es/event/online-ibec-seminar-xavier-trepat/
CATEGORIES:IBEC Seminar
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20201124T090000
DTEND;TZID=Europe/Madrid:20201125T182000
DTSTAMP:20260506T011752
CREATED:20200921T110920Z
LAST-MODIFIED:20201102T104949Z
UID:77365-1606208400-1606328400@ibecbarcelona.eu
SUMMARY:Bioengineering and MedTtech against cancer
DESCRIPTION:Bioengineering & MedTtech against cancer\n \n\n  \nTo meet the challenges in healthcare of the 21st century\, it is important to combined bioengineering and MedTech to develop biological system analyze and treatment to treat specifically cancer cells and protect the rest of the patient’s body by limiting side effects. To accomplish this\, we need to promote an innovation model where scientists\, engineers and doctors works together. \nIt’s in this optic that the digital oncology short course will take place the 24th and 25th of November 2020. This short course is part of ToHealth program\, an EIT Health activity. The course is organized by Medicen Paris and the Institute for Bioengineering of Catalonia (IBEC)\, with the collaboration of Biocat\, “la Caixa” Foundation and Meditecnologia\, under the framework of B·Debate. \nA 2 days workshop reviewing different bioengineering and medtech technologies (liquid biopsies\, targeted drug delivery\, tumor on chip\, mechanobiology and Car-T therapies…) which can significantly contribute to meet the challenges that the increasing prevalence of cancer poses on society and healthcare systems and what would be the difficulties that must be solved before these technologies are a reality in daily clinical practice. And also\, a transversal session to discuss barriers and opportunities for the translation of these technologies to the clinical practice. \n\nLocation: Online Event \n\nWe invite you to register at https://event.meetmaps.com/bioengineeringandmedtech/en/landing \n 
URL:https://ibecbarcelona.eu/es/event/bioengineering-and-medttech-against-cancer/
CATEGORIES:Joint seminar / workshop / symposium
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BEGIN:VEVENT
DTSTART;TZID=Europe/Madrid:20201125T000000
DTEND;TZID=Europe/Madrid:20201125T140000
DTSTAMP:20260506T011752
CREATED:20201120T124114Z
LAST-MODIFIED:20201120T124114Z
UID:79838-1606262400-1606312800@ibecbarcelona.eu
SUMMARY:PhD Thesis Defense: Jesús Ordoño
DESCRIPTION:Lactate: unraveling the regenerative potential for cardiac tissue engineering\nJesús Ordoño\, Biometerials for regenerative therapies grouop \nThis thesis defense will take place on the 25th November at 12.00 at Sala d’Actes de la Facultat de Matemàtiques i Estadística (FME)\, Campus Diagonal Sud. It is possible to attend to this defense but it will also be transmitted online at Google meet (meet.google.com/ufd-vtgp-gmd). \n  \n 
URL:https://ibecbarcelona.eu/es/event/phd-thesis-defense-jesus-ordono/
LOCATION:Sala d’Actes de la Facultat de Matemàtiques i Estadística (FME)\, Carrer de Pau Gargallo\, Barcelona\, 08028\, Spain
CATEGORIES:PhD Thesis Defence
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